Chlorhexidine Vaginal Preparation for Reduction of Post-cesarean Endometritis and Sepsis
Postpartum Endometritis, Wound Infection, Chlorhexidine Adverse Reaction
About this trial
This is an interventional prevention trial for Postpartum Endometritis focused on measuring post-cesarean endometritis, wound infection, chlorhexidine vaginal preparation, chlorhexidine adverse reaction
Eligibility Criteria
Inclusion Criteria:
- Gestational age ≥28 weeks.
- Cases had cesarean section after start of labor.
Exclusion Criteria:
- Women with known allergy to chlorhexidine gluconate or any of its ingredients.
- Women with diagnosed group B streptococcus (GBS) colonization.
- Women with active infection during the procedure.
- Women did not receive the standard preoperative antibiotic prophylaxis.
- Women with diagnosis of chorioamnionitis.
- Prolonged rupture of membranes >7 days
Sites / Locations
- Armed Forces Hospitals Southern Region
Arms of the Study
Arm 1
Arm 2
Experimental
No Intervention
Chlorhexidine vaginal prep.arm
No vaginal antiseptic arm
Women in labor who will receive vaginal cleaning immediately before cesarean section using 50 ml of chlorhexidine gluconate 0.05% solution and standard abdominal scrub with chlorhexidine gluconate 4%. This concentration is indicated within the British National Formulary for swabbing in obstetrics. A swab soaked in the antiseptic will be used to clean the vagina for 30 seconds prior to CS at the time of urinary catheter insertion by long forceps. After the CS procedure, the vagina is always cleaned of excess blood as with a dry swab.
Women in labor who will receive abdominal scrub with chlorhexidine gluconate 4% only. Vaginal preparation is not including antiseptic or using normal saline only.