Oral Colecalciferol Treatment in Spinal Cord Lesion
Spinal Cord Injury
About this trial
This is an interventional treatment trial for Spinal Cord Injury focused on measuring 25(OH)D, hand grip strength, Spinal cord injuries, muscle thickness
Eligibility Criteria
Inclusion Criteria:
- 18-60 years old
- Thoracic level chronic spinal cord injury
- A, B, C, D complete / incomplete patients according to ASIA classification
- 25 (OH) D3 level in serum is <20 ng / ml
- Complete muscle strength in upper extremity
Exclusion Criteria:
- Individuals with chronic liver, kidney, respiratory and parathyroid disease
- Chronic constipation
- Patients who have recently used vitamin D
- Use of drugs that will affect vitamin D and Ca level (Thiazide group diuretics, statins)
- Acute inflammation (may show false low in vitamin D levels)
Sites / Locations
- Istanbul Physical Medicine Rehabilitation Training & Research Hospital
Arms of the Study
Arm 1
Arm 2
Arm 3
Experimental
Experimental
No Intervention
weekly treatment group
daily treatment group
control group
Twenty patients with spinal cord injury with serum 25 (OH) D3 level less than 20 ng / ml will receive 50,000 IU of vitamin D weekly for 8 weeks.
Twenty patients with spinal cord injury with serum 25 (OH) D3 level less than 20 ng / ml will receive 6,000 IU of vitamin D daily for 8 weeks.
20 patients with high calcium (Ca) values in blood tests, patients with kidney and urinary stones, as well as patients who refuse to use vitamin D supplements will be included in the control group