Back to resultsEffect of Daily Doses of Rice or Whey Protein on Resistance Training Adaptations
Primary Purpose
Hypertrophy
Status
Completed
Phase
Not Applicable
Locations
United States
Study Type
Interventional
Intervention
Whey Protein
Sponsored by
About this trial
This is an interventional other trial for Hypertrophy
Eligibility Criteria
Inclusion Criteria:
- Between the ages of 18-50 years, although it is anticipated that the majority of participants will be between 18 and 35 years of age.
- Participants will be healthy and free of disease as determined by evaluation of a medical history
- All participants will be required to abstain from taking any additional forms of nutritional supplementation (preworkouts, creatine, beta-alanine, etc.) for four weeks prior to beginning this study and for the entire duration of the study.
Exclusion Criteria:
- Those individuals with less than 12 months of structured resistance training experience will be excluded from the study.
- Individuals whose maximal relative upper body strength is below 1.0 will be excluded.
- Individuals whose maximal relative lower body strength is below 1.50 will be excluded.
- As indicated on a medical history form they complete, any individual who is currently being treated for or diagnosed with a cardiac, respiratory, circulatory, musculoskeletal, metabolic, obesity (defined as body mass index > 30 kg/m2 and body fat greater than 30%), immune, autoimmune, psychiatric, hematological, neurological or endocrinological disorder or disease will be excluded.
- Those individuals who present with any previous injury or illness that would prevent them from appropriately completing all exercise lifts will be excluded from the study.
- Participants who are not able to fit onto the DEXA table will not be able to participate in the research due to size restrictions of the equipment. This typically includes individuals exceeding 300 pounds or those greater than 6 feet 6 inches.
- Those individuals less than 18 and greater than 50 years of age will be excluded. Participants younger than 18 are excluded due to necessity of parental consent. Participants greater than 50 years old lie outside of the target demographic for the current study.
- Participants who are determined to not be weight stable defined as week 0 and week 2 body mass levels deviating by 2% or more.
Sites / Locations
- Lindenwood University
Arms of the Study
Arm 1
Arm 2
Arm Type
Active Comparator
Active Comparator
Arm Label
Rice Protein
Whey Protein
Arm Description
Rice Protein - 24 grams, chocolate, powder
Whey Protein - 24 grams, chocolate, powder
Outcomes
Primary Outcome Measures
Changes in upper- and lower-body strength via Dual-Energy X-ray Absorptiometry
Examining how much strength each participant gains (or loses) from Day 1 to Final day
Changes in fat-free mass via Dual-Energy X-ray Absorptiometry
Examining the differences in fat-free mass from Day 1 to Final day
Secondary Outcome Measures
Changes in muscular endurance by counting repetitions for each exercise test
Examining the differences in muscular endurance from Day 1 to Final day
Changes in resistance training volume by tracking how many pounds were lifted during each exercise
Examining the differences in resistance training volume from Day 1 to Final day
Full Information
1. Study Identification
Unique Protocol Identification Number
NCT04411173
Brief Title
Effect of Daily Doses of Rice or Whey Protein on Resistance Training Adaptations
Official Title
Effect of Daily Doses of Rice or Whey Protein on Resistance Training Adaptations
Study Type
Interventional
2. Study Status
Record Verification Date
May 2020
Overall Recruitment Status
Completed
Study Start Date
September 12, 2018 (Actual)
Primary Completion Date
February 12, 2020 (Actual)
Study Completion Date
February 12, 2020 (Actual)
3. Sponsor/Collaborators
Responsible Party, by Official Title
Sponsor
Name of the Sponsor
Lindenwood University
4. Oversight
Studies a U.S. FDA-regulated Drug Product
No
Studies a U.S. FDA-regulated Device Product
No
Data Monitoring Committee
No
5. Study Description
Brief Summary
The purpose of this study is to compare the ability of isocaloric and isonitrogenous (2 x 15-gram) doses of rice protein or whey protein to stimulate resistance training adaptations in young, healthy, resistance-trained men.
Detailed Description
The study will be conducted using a randomized, double-blind approach with individuals being provided two doses of either 15 grams of rice or 15 grams of whey protein over an 8-week supplementation period while completing a heavy resistance training. One dose will be ingested within one hour of completing each workout and the other dose will be ingested within an hour of going to bed. On non-workout days, one dose of 30 grams will be ingested within 60 minutes of going to bed. The resistance training protocol will follow a linear periodization, split-body resistance training design consisting of two upper body and two lower body workouts each week resulting in each muscle group being trained twice each week. To minimize the influence of training experience and any learning effect, individuals with at least 12 months of resistance training history will be recruited. Participants will also be required to complete a two-week lead-in period (8 total workouts) before beginning the supplementation regimen to become accustomed to the training program and to account for any early neurological adaptations. Participants will then continue to follow the resistance training program for an additional 8 weeks. To assess the efficacy of the two different forms of protein supplementation on resistance training adaptations, changes in fat-free, lean, and fat mass will be determined using DEXA. Maximal strength and endurance of both upper and lower-body muscle groups will be determined while anaerobic capacity markers will be measured with the completion of a Wingate anaerobic capacity test. Participants will also be provided nutritional recommendations in order to ensure adequate energy and macronutrient consumption to facilitate positive training adaptations and eliminate any potential influence of differing dietary intakes.
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Hypertrophy
7. Study Design
Primary Purpose
Other
Study Phase
Not Applicable
Interventional Study Model
Parallel Assignment
Masking
ParticipantInvestigator
Masking Description
The supplements were delivered in identical containers with rather an "A" or "B" marked on the outside of the bag. Once data collection, data entry, and statistical analysis was completely finished, the study code was broken.
Allocation
Randomized
Enrollment
24 (Actual)
8. Arms, Groups, and Interventions
Arm Title
Rice Protein
Arm Type
Active Comparator
Arm Description
Rice Protein - 24 grams, chocolate, powder
Arm Title
Whey Protein
Arm Type
Active Comparator
Arm Description
Whey Protein - 24 grams, chocolate, powder
Intervention Type
Dietary Supplement
Intervention Name(s)
Whey Protein
Other Intervention Name(s)
Rice Protein
Intervention Description
Each condition (both rice and whey protein) match in color, flavor, and serving size.
Primary Outcome Measure Information:
Title
Changes in upper- and lower-body strength via Dual-Energy X-ray Absorptiometry
Description
Examining how much strength each participant gains (or loses) from Day 1 to Final day
Time Frame
Eight weeks
Title
Changes in fat-free mass via Dual-Energy X-ray Absorptiometry
Description
Examining the differences in fat-free mass from Day 1 to Final day
Time Frame
Eight weeks
Secondary Outcome Measure Information:
Title
Changes in muscular endurance by counting repetitions for each exercise test
Description
Examining the differences in muscular endurance from Day 1 to Final day
Time Frame
Eight weeks
Title
Changes in resistance training volume by tracking how many pounds were lifted during each exercise
Description
Examining the differences in resistance training volume from Day 1 to Final day
Time Frame
Eight weeks
10. Eligibility
Sex
Male
Minimum Age & Unit of Time
18 Years
Maximum Age & Unit of Time
50 Years
Accepts Healthy Volunteers
Accepts Healthy Volunteers
Eligibility Criteria
Inclusion Criteria:
Between the ages of 18-50 years, although it is anticipated that the majority of participants will be between 18 and 35 years of age.
Participants will be healthy and free of disease as determined by evaluation of a medical history
All participants will be required to abstain from taking any additional forms of nutritional supplementation (preworkouts, creatine, beta-alanine, etc.) for four weeks prior to beginning this study and for the entire duration of the study.
Exclusion Criteria:
Those individuals with less than 12 months of structured resistance training experience will be excluded from the study.
Individuals whose maximal relative upper body strength is below 1.0 will be excluded.
Individuals whose maximal relative lower body strength is below 1.50 will be excluded.
As indicated on a medical history form they complete, any individual who is currently being treated for or diagnosed with a cardiac, respiratory, circulatory, musculoskeletal, metabolic, obesity (defined as body mass index > 30 kg/m2 and body fat greater than 30%), immune, autoimmune, psychiatric, hematological, neurological or endocrinological disorder or disease will be excluded.
Those individuals who present with any previous injury or illness that would prevent them from appropriately completing all exercise lifts will be excluded from the study.
Participants who are not able to fit onto the DEXA table will not be able to participate in the research due to size restrictions of the equipment. This typically includes individuals exceeding 300 pounds or those greater than 6 feet 6 inches.
Those individuals less than 18 and greater than 50 years of age will be excluded. Participants younger than 18 are excluded due to necessity of parental consent. Participants greater than 50 years old lie outside of the target demographic for the current study.
Participants who are determined to not be weight stable defined as week 0 and week 2 body mass levels deviating by 2% or more.
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Chad Kerksice, PhD
Organizational Affiliation
Laboratory Director
Official's Role
Study Director
Facility Information:
Facility Name
Lindenwood University
City
Saint Charles
State/Province
Missouri
ZIP/Postal Code
63301
Country
United States
12. IPD Sharing Statement
Plan to Share IPD
No
IPD Sharing Plan Description
All approved unidentified study data inside the laboratory will be saved within a research repository bank for future research questions. Otherwise, participant data will be destroyed after three years of study completion to maintain IRB compliance.
Citations:
PubMed Identifier
33261645
Citation
Moon JM, Ratliff KM, Blumkaitis JC, Harty PS, Zabriskie HA, Stecker RA, Currier BS, Jagim AR, Jager R, Purpura M, Kerksick CM. Effects of daily 24-gram doses of rice or whey protein on resistance training adaptations in trained males. J Int Soc Sports Nutr. 2020 Dec 1;17(1):60. doi: 10.1186/s12970-020-00394-1.
Results Reference
derived
Learn more about this trial
Effect of Daily Doses of Rice or Whey Protein on Resistance Training Adaptations
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