Core Warming of COVID-19 Patients
COVID 19
About this trial
This is an interventional treatment trial for COVID 19 focused on measuring COVID 19, Warming, Mechanical ventilation
Eligibility Criteria
Inclusion Criteria:
- Patients above the age of 18 years old.
- Patients with a diagnosis of COVID-19 on mechanical ventilation.
- Patient maximum baseline temperature (within previous 12 hours) < 38.3°C.
- Patients must have a surrogate or legally authorized representative able to understand and critically review the informed consent form.
Exclusion Criteria:
- Patients without surrogate or legally authorized representative able to provide informed consent.
- Patients with contraindication to core warming using an esophageal core warming device.
- Patients known to be pregnant.
- Patients with <40 kg of body mass.
- Patients with DNR status.
- Patients with acute stroke, post-cardiac arrest, or multiple sclerosis.
- Patients with history of esophageal disease
- Patients with a baseline epinephrine dose greater than 0.6 mcg/kg/min
- Patients with atrial fibrillation, atrial flutter, or other multifocal atrial tachycardia with a heart rate greater than 110 beats per minute.
- Patients on 0.2 mcg/kg/min or more of norepinephrine
Sites / Locations
- Barnes-Jewish Hospital
Arms of the Study
Arm 1
Arm 2
Experimental
No Intervention
Group A - core warming
Group B - Control Group
Patients randomized to Group A will have core warming with the ensoETM device initiated in the ICU or other clinical environment in which they are being treated. The device will be used as indicated (for warming). Patient temperature measurement will be collected for both the core warming and standard of care arms during the study period (72 hours).
Group B is serving as the control group who will not have the ensoETM device used.Control group patients will be managed as per standard of care currently utilized in the ICU, which will include the use of other methods of temperature management as warranted. This would include warming with a forced air blanket only in hypothermic patients (core temperature < 36°C) or antipyretic therapy for febrile patients, as requested by the treating physician.