Intact Cord Resuscitation in CDH (CHIC)
Rare Diseases, Congenital Diaphragmatic Hernia
About this trial
This is an interventional treatment trial for Rare Diseases focused on measuring Congenital diaphragmatic hernia, resuscitation, delayed cord clamping, newborn
Eligibility Criteria
Inclusion Criteria:
- Antenatal diagnosis of CDH
- No severe additional malformation or chromosomal diseases
- Full term (>36 weeks gestational age)
- No inclusion in another antenatal trial
- Written informed consents from the parents
Exclusion Criteria:
- Preterm birth less than 37 weeks gestational age
- Other severe malformation(s) or chromosomal diseases
- Twin
- Parents who may have French language understanding difficulties may not participate to the study unless they receive appropriate assistance regarding the understanding of the formal consent forms needed to get included in the study. If included in the study, regarding their French understanding level, the parents may not be proposed the auto questionnaires and interviews led by the psychologist
Sites / Locations
- Chu Amiens PicardieRecruiting
- Hop Jeanne de Flandre Chu LilleRecruiting
- Chu de Nantes -Recruiting
Arms of the Study
Arm 1
Arm 2
Active Comparator
Experimental
Immediate umbilical cord clamping
Intact cord resuscitation
This group includes newborn infants with isolated CDH who will benefit from the standardized CDH management procedure as described in the French national CDH management guidelines ("Programme National de Soins").The resuscitation maneuvers are started after the umbilical cord is clamped.
This group includes newborn infants with isolated CDH who will benefit from the standardized CDH resuscitation maneuvers as described in the French national CDH management guidelines ("Programme National de Soins") before the umbilical cord is clamped. The resuscitation maneuvers are started at birth while the umbilical cord still bridges mother and child.