Use of Tranexamic Acid in Liposculpture
Blood Loss, Surgical
About this trial
This is an interventional treatment trial for Blood Loss, Surgical focused on measuring Tranexamic Acid, Blood Loss, Liposculpture
Eligibility Criteria
Inclusion Criteria:
- Patients that underwent liposculpture as unique procedure, surgical time between 2 and 5 hours, age between 20 and 45 years old and BMI between 20 and 30 m2/kg.
Exclusion Criteria:
- Patients that were operated of liposculpture and any additional procedure (Mammoplasty, tummy tuck, etc.), patients with history of thromboembolic disease or in Treatment with aspirin within 14 days before surgery or anticoagulants within 5 days prior to surgery, patients with history of epilepsy, patients with allergy to tranexamic acid, comorbidity grade III or IV according to ASA (American society of Anesthesiologists) and patients with prothrombin time (PT) and/or activated partial thromboplastin time (aPTT) >1.5 times the baseline.
Sites / Locations
- Dhara clinic
- Innovare hospital
- Centro Medico de las Americas clinic
Arms of the Study
Arm 1
Arm 2
Arm 3
Placebo Comparator
Experimental
Experimental
Placebo group
Intravenous group
Subcutaneous group
No use of tranexamic acid. Subcutaneous infiltration of normal saline solution plus 1 mg of epinephrine as required for the procedure.
A single dose of 1 gr of tranexamic acid (10 ml) IV, thirty minutes previous to the initiation of the surgery. Subcutaneous infiltration of normal saline solution plus 1 mg of epinephrine as required for the procedure.
A single dose of 1 gr of tranexamic acid (10 ml) in the total of the infiltration mixture, as follow: 4 liters of infiltration contents 2.5 ml of tranexamic acid plus 1 mg epinephrine 5 liters of infiltration contents 2 ml of tranexamic acid plus 1 mg epinephrine. 6 liters of infiltration contents 1.6 ml of tranexamic acid plus 1 mg epinephrine.