Efficacy of Li-SWT on Persistent Storage Symptoms After Transurethral Surgery for BPO
Overactive Bladder, Urinary Incontinence, Urge, Urgency-frequency Syndrome
About this trial
This is an interventional treatment trial for Overactive Bladder focused on measuring low-intensity shock wave therapy, persistent storage symptoms, benign prostatic obstruction
Eligibility Criteria
Inclusion Criteria:
Patients have to fulfill all the following criteria to be included in the study:
- Ability to give informed consent and reply to questionnaires.
- Average urgency episodes per 24 hrs ≥ 1 and average daytime frequency ≥ 8 during the baseline 3-day voiding diary.
- Relief of BOO as proved by non-invasive uroflowmetry, pressure flow study (PFS) or urethrocystoscopy.
Exclusion Criteria:
Patients who have any of the following will be excluded from the study:
- Untreated UTI.
- BOO such as bladder neck contracture (BNC), residual obstructing adenoma or urethral stricture.
- Neurogenic lower urinary tract dysfunction (LUTD).
- Uncontrolled diabetes mellitus.
- Depression or any psychogenic disorders.
- Prior radiation therapy to the pelvic area.
- History of prostate cancer, bladder tumor or intravesical Bacillus Calmette Guerin (BCG) therapy.
- Poor coagulopathy.
- Severe cardiovascular disease.
Sites / Locations
- Urology and Nephrology center
Arms of the Study
Arm 1
Arm 2
Arm 3
Active Comparator
Sham Comparator
Active Comparator
Li-SWT
Sham treatment
antimuscarinics
Patients will be treated by 8 sessions of Li-SWT with one week interval. This group is subdivided into 3 subgroups according to the approach through which Li-SWT is applied; suprapubic, perineal and combined approaches
Patients will be treated by 8 sessions of sham treatment with one week interval, applied through suprapubic and perineal approaches.
Patients will be treated by solifenacin 10 mg once daily for 6 months.