Clinical Evaluation of Dimethyl Sulfoxide Dentin Pre-treatment
Dental Diseases
About this trial
This is an interventional treatment trial for Dental Diseases focused on measuring DMSO
Eligibility Criteria
Inclusion Criteria:
- Patients with cervical lesions.
- Co-operative patients approving to participate in the study.
- Pulp is asymptomatic vital teeth.
- Presence of favorable occlusion and teeth are in normal contact with the adjacent teeth.
Exclusion Criteria:
- Xerostomia.
- Bruxism and visible wear facets in the posterior dentition.
- Known inability to return for recall appointments.
- Fractured or visibly cracked candidate tooth.
- Current desensitizing therapy, including desensitizing dentifrices or other over-the-counter (OTC) products.
- Long-term use of anti-inflammatory, analgesic, or psychotropic drugs.
- Pregnancy or breastfeeding (potential conflicts with recall dates.
- Allergies to ingredients of resin-based restorative materials.
- Orthodontic appliance treatment within the previous three months.
- Abutment teeth for fixed or removable prostheses.
- Teeth or supporting structures with any symptomatic pathology.
- Existing periodontal disease or periodontal surgery within the previous three months.
Sites / Locations
- Faculty of Dentistry, Cairo University
Arms of the Study
Arm 1
Arm 2
Active Comparator
Experimental
3M single bond, etch and rinse adhesive
DMSO pre-treatment before 3M single bond application
O.I. will clean the labial surface of tooth with polishing paste and brush Roughening of the surface may be needed by diamond point The tooth will be isolated by rubber dam. Apply etchant for 30 s for enamel and 15 s for dentin. Rinse thoroughly with water for 10 s. blot-drying with paper tissue was carefully performed leaving the dentin surface slightly moist. Apply 2 to 3 consecutive coats of the adhesive for 15 s. Gently air for 5 s. Light cure for 10 s. Composite build ups (Filtek Z350 XT, 3 M ESPE, St Paul, MN, USA) were performed in increments and individually light-cured for 40 s. Light curing of all resin materials was performed using a LED device (Bluephase 20i, Ivoclare Vivadent, Schaan, Liechtenstein) delivering 1100 mW/cm2.
The same steps of the comparator group with additional step, after dentin etching and humidity control, dentin pretreatments were performed consisting of active application of 1% DMSO/H2O solutions on etched-dentin followed by blot drying until paper filters no longer absorbed liquids from the bonding surface by capillarity then apply adhesive.