Do Discounted Vouchers for Medical Cannabis Reduce Opioid Use in Adults With Pain (ReLeaf-V)
Opioid Use, Marijuana, Chronic Pain
About this trial
This is an interventional treatment trial for Opioid Use focused on measuring opioid, marijuana, cannabis, pain
Eligibility Criteria
Inclusion Criteria:
- >18 years old
- English or Spanish fluency
- active certification for medical cannabis
- intends to have a soft-gel capsule product dispensed at Vireo Health
- medical cannabis qualifying conditions or complications of (a) chronic pain, or (b) pain that degrades health and functional capability as an alternative to opioid use or substance use disorder or (c) severe or chronic pain
- joint or neuropathic pain
- current severe pain
- dispensed opioids analgesics within the last 60 days
To maintain the integrity of the study, we do not disclose all inclusion criteria to potential participants.
Exclusion Criteria:
- inability to provide informed consent
- inability to complete study visits over 14 weeks
- terminal illness
- current or prior psychotic disorder
- current or prior buprenorphine or methadone treatment for opioid use disorder
- NYS medical marijuana prescriber does not approve changes to product and dosing recommendations listed on the participant's certification form
- Allergy to tapioca or coconut
- currently pregnant, planning to become pregnant within the next 3 months, or breastfeeding
- a condition that is considered by a pharmacist or medical provider to be a clinical contraindication to medical cannabis use (e.g. unstable cardiac arrhythmia or specific drug-drug interaction)
Sites / Locations
- Vireo Health of New YorkRecruiting
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Placebo Comparator
Experimental
Experimental
Experimental
Voucher for a Discounted Placebo Product
Voucher for a Discounted High THC:Low CBD Product
Voucher for a Discounted Equal THC:CBD Product
Voucher for a Discounted Low THC:High CBD Product
Voucher for a Discounted Placebo Soft-Gel Capsule Product
Voucher for a Discounted 4.3mg THC/0.7mg CBD Soft-Gel Capsule Product
Voucher for a Discounted 2.5mg THC/2.5mg CBD Soft-Gel Capsule Product
Voucher for a Discounted 0.2mg THC/4.8mg CBD Soft-Gel Capsule Product