Evaluate the Efficacy of Herbal Medicine (Shaoyao Gancao Decoction Jiawei) in Sleep-related Leg Cramps
Sleep-related Leg Cramps
About this trial
This is an interventional treatment trial for Sleep-related Leg Cramps
Eligibility Criteria
Inclusion Criteria:
- Aged 60-80
- Complain of muscular spasm and contracture of a limb with difficulty in relaxation and movement during night time, caused by wind-cold dampness chiefly involving the sinews
- SRLCs occur at least once in the past 7 days or twice in the past 14 days
- Visual Analogue Scale (VAS) for leg cramp ≥ 5 (0-10) at the last attack
- Both gender but menopause or sterilization for female subjects
- Able to fill up the VAS for leg cramp
- Written informed consent obtained
Exclusion Criteria:
1. Known mental disorder 2. Known serious organic disease including severe coronary function impairment, post-stroke depression and dementia, and auto-immune diseases 3. Known history of renal or liver function impairment; 4. Patients whose blood tests show exclusion criteria 5. Currently taking anticoagulant or antiplatelet 6. Any contraindications for taking herb confirmed by investigator
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Sites / Locations
- The Chinese University of Hong Kong
Arms of the Study
Arm 1
Experimental
Shaoyao Gancao Decoction Jiawei
Shaoyao Gancao Decoction Jiawei by adding Pueraria montana, Salvia Miltiorrhiza, into Shaoyao Gancao. The medication will be taken twice daily for 28 consecutive days. Each prescription will consist of 4 herbal granules.