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Efficacy of Hip Strengthening on Dynamic Knee Stability, Disability and Gait in Knee Osteoarthritis

Primary Purpose

Knee Osteoarthritis

Status
Unknown status
Phase
Not Applicable
Locations
Study Type
Interventional
Intervention
hip strengthening
quadriceps strengthening, stretch hamstring,cuff muscles
Sponsored by
Cairo University
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional treatment trial for Knee Osteoarthritis

Eligibility Criteria

40 Years - 65 Years (Adult, Older Adult)All SexesAccepts Healthy Volunteers

Inclusion Criteria:

age 40 to 65 years grade 2-3 on KL grade BMI 25 to 32 kg/m2 medial KOA

Exclusion Criteria:

  • lateral KOA intraarticular corticosteriod injection into knee within pervious 3 months significant comorbidity individuals with known hip osteoarthritis previous trauma affection one or both hips history of other medical conditions affecting the knee joint previous replacement of any joint in the lower extremity low back pain cognitive impairment

Sites / Locations

    Arms of the Study

    Arm 1

    Arm 2

    Arm Type

    Experimental

    Active Comparator

    Arm Label

    hip strengthening

    quadriceps strengthening, stretch for hamstring,cuff muscles

    Arm Description

    resistance training for hip abductor, hip extensor, and hip external rotator will be performed.cuff weights will be used with 80% of 1 repetition maximum at 3 sets of 8 repetitions with 10-15 second rest between repetitions and 1-2 minute rest between sets.

    quadriceps strengthening: multi-angle isometric exercise from sitting position will be performed. cuff weights will be used with 3 sets of 12 repetitions at 40% of 1 reprtition maximum. self stretch for hamstring and cuff muscles from supine position. the procedure will be repeated 4 times.

    Outcomes

    Primary Outcome Measures

    dynamic knee stability
    dynamic knee stability will be measured by frontal plane projection angle

    Secondary Outcome Measures

    Full Information

    First Posted
    August 3, 2020
    Last Updated
    December 28, 2020
    Sponsor
    Cairo University
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    1. Study Identification

    Unique Protocol Identification Number
    NCT04509830
    Brief Title
    Efficacy of Hip Strengthening on Dynamic Knee Stability, Disability and Gait in Knee Osteoarthritis
    Official Title
    Efficacy of Hip Strengthening on Dynamic Knee Stability, Disability and Gait in Knee Osteoarthritis
    Study Type
    Interventional

    2. Study Status

    Record Verification Date
    December 2020
    Overall Recruitment Status
    Unknown status
    Study Start Date
    January 1, 2021 (Anticipated)
    Primary Completion Date
    September 1, 2021 (Anticipated)
    Study Completion Date
    October 2021 (Anticipated)

    3. Sponsor/Collaborators

    Responsible Party, by Official Title
    Principal Investigator
    Name of the Sponsor
    Cairo University

    4. Oversight

    Studies a U.S. FDA-regulated Drug Product
    No
    Studies a U.S. FDA-regulated Device Product
    No

    5. Study Description

    Brief Summary
    this study will be conducted to investigate the role of hip strengthening in improving dynamic knee stability, gait parameter, lower extremity strength and disability in knee osteoarthritis
    Detailed Description
    knee osteoarthritis accounts for more than 80% of the total burden of the diseases. patients with knee osteoarthritis had worse spatiotemporal gait parameter and dynamic instabitity. there are significant hip muscle weakness in knee osteoarthritis. hip muscle weakness leads to improper alignment and stress in knee joint. hip muscle strength can affect knee joint loading and disease progression in knee osteoarthritis. muscles of the lower extremity play a critical role in the preservation of normal knee joint function by providing dynamic knee joint stability and shock absorption, while maintaining safe transfer of forces across the joint.

    6. Conditions and Keywords

    Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
    Knee Osteoarthritis

    7. Study Design

    Primary Purpose
    Treatment
    Study Phase
    Not Applicable
    Interventional Study Model
    Parallel Assignment
    Model Description
    randomized control trial
    Masking
    Care ProviderOutcomes Assessor
    Masking Description
    double blinded
    Allocation
    Randomized
    Enrollment
    88 (Anticipated)

    8. Arms, Groups, and Interventions

    Arm Title
    hip strengthening
    Arm Type
    Experimental
    Arm Description
    resistance training for hip abductor, hip extensor, and hip external rotator will be performed.cuff weights will be used with 80% of 1 repetition maximum at 3 sets of 8 repetitions with 10-15 second rest between repetitions and 1-2 minute rest between sets.
    Arm Title
    quadriceps strengthening, stretch for hamstring,cuff muscles
    Arm Type
    Active Comparator
    Arm Description
    quadriceps strengthening: multi-angle isometric exercise from sitting position will be performed. cuff weights will be used with 3 sets of 12 repetitions at 40% of 1 reprtition maximum. self stretch for hamstring and cuff muscles from supine position. the procedure will be repeated 4 times.
    Intervention Type
    Other
    Intervention Name(s)
    hip strengthening
    Intervention Description
    resistance training for hip abductor, hip extensor, and hip external rotator
    Intervention Type
    Other
    Intervention Name(s)
    quadriceps strengthening, stretch hamstring,cuff muscles
    Intervention Description
    multi-angle isometric quadriceps strengthening and hamstring and cuff self stretch
    Primary Outcome Measure Information:
    Title
    dynamic knee stability
    Description
    dynamic knee stability will be measured by frontal plane projection angle
    Time Frame
    baseline

    10. Eligibility

    Sex
    All
    Minimum Age & Unit of Time
    40 Years
    Maximum Age & Unit of Time
    65 Years
    Accepts Healthy Volunteers
    Accepts Healthy Volunteers
    Eligibility Criteria
    Inclusion Criteria: age 40 to 65 years grade 2-3 on KL grade BMI 25 to 32 kg/m2 medial KOA Exclusion Criteria: lateral KOA intraarticular corticosteriod injection into knee within pervious 3 months significant comorbidity individuals with known hip osteoarthritis previous trauma affection one or both hips history of other medical conditions affecting the knee joint previous replacement of any joint in the lower extremity low back pain cognitive impairment
    Central Contact Person:
    First Name & Middle Initial & Last Name or Official Title & Degree
    heba elsaeed
    Phone
    01066451851
    Email
    hebaelsayed880@yahoo.com
    First Name & Middle Initial & Last Name or Official Title & Degree
    Enas youssef
    Phone
    01127867507
    Email
    enas.fawzy@pt.cu.edu.eg

    12. IPD Sharing Statement

    Learn more about this trial

    Efficacy of Hip Strengthening on Dynamic Knee Stability, Disability and Gait in Knee Osteoarthritis

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