Comparison of BL and KTP Laser for Treatment of Benign Vocal Fold Lesions
Voice Disorders, RRP
About this trial
This is an interventional treatment trial for Voice Disorders focused on measuring KTP, Blue light laser, laryngology, in office procedures
Eligibility Criteria
Inclusion Criteria:
- Provision of signed and dated informed consent form;
- Stated willingness to comply with all study procedures and availability for the duration of the study;
- Male and female, aged ≥ 18 years; and
- Diagnosed with benign vocal fold lesions such as papillomas and polyps and who are candidates for elective in office laser treatment for these lesions.
Exclusion Criteria:
- < 18 years old;
- Current smokers;
- Vocal fold lesions such as vocal fold leukoplakia and vocal fold cancer;
- Systemic steroid use; and
- History of systemic illness that can affect wound healing.
Sites / Locations
Arms of the Study
Arm 1
Arm 2
Active Comparator
Experimental
KTP laser treatment
BL laser treatment
All participants will complete a paper Voice Handicap Index-10 (VHI-10) questionnaire and laryngeal stroboscopy examination at baseline. Local anesthesia will be administered as per standard of care for in-office laryngeal procedures. KTP laser will be utilized to ablate the lesion of interest. Immediately following the procedure, participants will complete a VAS pain scale on paper. Participants will be asked to exercise 3 days of absolute voice rest following the procedure. All patients will have follow-up clinic appointments on POD 7, POD 30, and POD 90 after surgery. At each of the follow-up visit, the patients will fill out a paper VHI-10 questionnaire and undergo stroboscopic examination to assess vocal fold vibratory properties and closure, as well as residual lesions. During the first week post procedure, the participants will continue to complete a daily VAS at home for pain assessment.
The only difference in study procedures between the experimental arm and the control arm is that the experimental arm will use the BL laser. The post-operative instructions and follow-up schedule are identical.