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A Study of MK-3655 in Individuals With Pre-cirrhotic Nonalcoholic Steatohepatitis (NASH) (MK-3655-001)

Primary Purpose

Nonalcoholic Steatohepatitis

Status
Terminated
Phase
Phase 2
Locations
International
Study Type
Interventional
Intervention
MK-3655
Placebo
Sponsored by
Merck Sharp & Dohme LLC
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional treatment trial for Nonalcoholic Steatohepatitis focused on measuring Non-alcoholic fatty liver disease

Eligibility Criteria

18 Years - 80 Years (Adult, Older Adult)All SexesDoes not accept healthy volunteers

Inclusion Criteria:

  1. Has histological confirmation of NASH
  2. Is a male or female aged 18 years to 80 years (in Japan and Taiwan aged 20 to 80 years)
  3. Has a body mass index (BMI) ≥25 kg/m^2 and ≤50 kg/m^2 and stable weight for the past 3 months
  4. Has no history of Type 2 diabetes mellitus (T2DM) OR a history of T2DM controlled by diet or stable doses of antihyperglycemic agents (AHAs)
  5. Contraceptive use by male participants should be consistent with local regulations.
  6. A female participant is eligible to participate if she is not pregnant or breastfeeding, and she is not a woman of child-bearing potential (WOCBP) OR she is a WOCBP and uses a contraceptive method that is highly effective during the intervention period and for at least 16 weeks after the last dose of study intervention.

Exclusion Criteria

  1. Has presence of cirrhosis on liver biopsy
  2. Has Type 1 diabetes
  3. Has a history of malignancy, unless cancer free ≥5 years, or is under evaluation for active or suspected malignancy except for adequately treated basal cell or squamous cell skin cancer or in situ cervical cancer
  4. Has a history of bariatric surgery ≤5 years before study participation
  5. Has undergone a major surgical procedure ≤3 months before study participation or has major surgery planned during the study
  6. Has a history or evidence of chronic liver disease other than NASH. Individuals with a history of Hepatitis B or C may be eligible for participation.
  7. Has significant systemic or major illnesses other than liver disease, including recent events (≤6 months before study entry) of congestive heart failure, unstable coronary artery disease, arterial revascularization, pulmonary disease, renal failure, stroke, transient ischemic attack, or organ transplantation

Sites / Locations

  • Adobe Clinical Research, LLC ( Site 2644)
  • Arizona Liver Health ( Site 9026)
  • Del Sol Research Management ( Site 2674)
  • Arkansas Gastroenterology - North Little Rock ( Site 9015)
  • Hope Clinical Research, Inc. ( Site 2601)
  • Velocity Clinical Research, Huntington Park ( Site 9022)
  • UCSD - Altman Clinical and Translational Research Institute -UC San Diego NAFLD Research Center ( Si
  • Ruane Clinical Research Group, Inc ( Site 9014)
  • Velocity Clinical Research, Westlake ( Site 9013)
  • Catalina Research Institute, LLC ( Site 2643)
  • Velocity Clinical Research, Panorama City ( Site 9001)
  • California Liver Research Institute ( Site 9025)
  • Quest Clinical Research ( Site 9011)
  • Velocity Clinical Research, Santa Ana ( Site 9002)
  • Peak Gastroenterology Associates ( Site 2645)
  • Top Medical Research, Inc ( Site 2673)
  • Covenant Metabolic Specialists, LLC ( Site 9027)
  • North Florida South Georgia Veterans Health System ( Site 2613)
  • Indago Research and Health Center Inc ( Site 2610)
  • Sweet Hope Research Specialty Inc ( Site 2660)
  • Floridian Clinical Research, LLC ( Site 2656)
  • Ocean Blue Medical Research Center Inc ( Site 2667)
  • Genoma Research Group, Inc. ( Site 2669)
  • Sensible Healthcare Llc ( Site 2607)
  • Synexus Research ( Site 2672)
  • Southeast Clinical Research Center ( Site 9003)
  • The University of Iowa ( Site 2655)
  • Legacy Clinical Solutions: Tandem Clinical Research, LLC ( Site 2650)
  • The National Diabetes & Obesity Research Institute ( Site 9017)
  • Kansas City Research Institute ( Site 9018)
  • Excel Clinical Research, LLC ( Site 2603)
  • Velocity Clinical Research, Syracuse ( Site 9016)
  • NYU Langone Health, New York ( Site 2627)
  • Hillmont G.I. ( Site 9019)
  • Regional Gastroenterology Associates of Lancaster, LTD ( Site 9020)
  • Regional Gastroenterology Associates of Lancaster, LTD ( Site 9004)
  • Premier Medical Group ( Site 9010)
  • Texas Clinical Research Institute ( Site 2619)
  • The Liver Institute at Methodist Dallas Medical Center ( Site 2638)
  • DHR Health Institute for Research and Development ( Site 9006)
  • South Texas Research Institute ( Site 9012)
  • Baylor College of Medicine - Advanced Liver Therapies ( Site 2670)
  • The Crofoot Research Center, Inc. ( Site 2611)
  • Quality Research ( Site 9024)
  • American Research Corporation at Texas Liver Institute ( Site 2634)
  • Clinical Trials of Texas, LLC ( Site 2614)
  • Impact Research Institute ( Site 2685)
  • Virginia Commonwealth University Health System ( Site 2657)
  • Instituto de Investigaciones Clínicas Mar del Plata ( Site 0010)
  • Hospital Universitario Austral ( Site 0003)
  • DIM Clínica Privada ( Site 0011)
  • Hospital Británico de Buenos Aires ( Site 0002)
  • Glenny Corp. S.A.-CLINICAL RESEARCH ( Site 0013)
  • Hospital Italiano de Buenos Aires-Hepatology ( Site 0014)
  • Hospital Provincial del Centenario ( Site 0007)
  • Hospital Aleman ( Site 0009)
  • Clinica de nefrologia urologia y enfermedades cardiovasculares ( Site 0008)
  • Royal Prince Alfred Hospital ( Site 0102)
  • St George Hospital ( Site 0104)
  • Flinders Medical Centre ( Site 0107)
  • GIRI GI Research Institute - Vancouver ( Site 0404)
  • University Health Network - Toronto General Hospital ( Site 0401)
  • McGill University Health Centre ( Site 0400)
  • Hospital Regional de Concepcion ( Site 0505)
  • Hospital San Juan de Dios de La Serena ( Site 0500)
  • Clinical Research Chile SpA ( Site 0506)
  • Enroll SpA ( Site 0508)
  • Pontificia Universidad Catolica de Chile ( Site 0501)
  • Centro de Investigaciones Clinicas Vina del Mar ( Site 0502)
  • Beijing YouAn Hospital, Capital Medical University ( Site 0605)
  • Chongqing Three Gorges Central Hospital ( Site 0618)
  • The First People's Hospital of Foshan-Infection Department ( Site 0612)
  • General Hospital of Ningxia Medical University ( Site 0607)
  • Xinhua Hospital Affiliated to Jiaotong University School of Medicine ( Site 0602)
  • The Affiliated Hospital of Hangzhou Normal University ( Site 0600)
  • Fundacion Santa Fe de Bogota ( Site 0705)
  • CHU de Nice Hopital de l Archet II ( Site 0800)
  • hopital haut leveque chu de bordeaux-Service d'Hépato-gastroentérologie ( Site 0805)
  • Hopital de la Croix-Rousse ( Site 0809)
  • CHU Dijon Bourgogne - Hopital F. Mitterrand ( Site 0816)
  • CHU Besançon ( Site 0806)
  • Centre Hospitalier et Universitaire Dupuytren ( Site 0810)
  • Hôpital Beaujon ( Site 0804)
  • C.H.U. Nancy Hopital de Brabois ( Site 0803)
  • Hôpital Claude Huriez ( Site 0811)
  • Hopital Henri Mondor ( Site 0808)
  • A.P.H. Paris, Hopital Saint Antoine ( Site 0807)
  • Hopital de la Pitie Salpetriere ( Site 0813)
  • Hopitaux Universitaires Paris Centre-Hopital Cochin ( Site 0812)
  • Universitaetsklinikum Freiburg ( Site 0446)
  • Universitätsklinikum Frankfurt-Medizinische Klinik 1 ( Site 0445)
  • Johannes Gutenberg Universitat Mainz ( Site 0442)
  • Universitaetsklinikum Leipzig ( Site 0447)
  • Charite Universitaetsmedizin Berlin ( Site 0443)
  • Hippokration University Hopsital-4th Department of Internal Medicine ( Site 3300)
  • Queen Mary Hospital ( Site 1003)
  • Prince of Wales Hospital ( Site 1001)
  • Prince of Wales Hospital ( Site 1002)
  • Rambam Medical Center ( Site 1201)
  • Carmel Medical Center ( Site 1203)
  • Shaare Zedek Medical Center ( Site 1205)
  • Rabin Medical Center ( Site 1204)
  • Chaim Sheba Medical Center ( Site 1200)
  • Maccabi Health Services - Ramat Hasharon ( Site 1206)
  • Sourasky Medical Center ( Site 1202)
  • IRCCS Istituto Clinico Humanitas di Rozzano ( Site 1303)
  • A O U Policlinico di Modena ( Site 1307)
  • Azienda Ospedaliera Policlinico Umberto I ( Site 1300)
  • Azienda Ospedaliera Universitaria Integrata Verona ( Site 1301)
  • Aichi Medical University Hospital ( Site 1402)
  • Ehime University Hospital ( Site 1417)
  • Ogaki Municipal Hospital ( Site 1409)
  • Hokkaido P.W.F.A.C Sapporo-Kosei General Hospital ( Site 1404)
  • Kanazawa University Hospital ( Site 1419)
  • Kagawa University Hospital ( Site 1414)
  • Kagawa Prefectural Central Hospital-liver intemal medicine ( Site 1416)
  • Shinyurigaoka General Hospital ( Site 1420)
  • Yokohama City University Hospital ( Site 1411)
  • Nara Medical University Hospital ( Site 1407)
  • Saiseikai Suita Hospital ( Site 1403)
  • Fukui-ken Saiseikai Hospital ( Site 1410)
  • Gifu Municipal Hospital ( Site 1408)
  • Hiroshima University Hospital ( Site 1413)
  • Kagoshima University Hospital ( Site 1418)
  • University Hospital, Kyoto Prefectural University of Medicine ( Site 1405)
  • Kawasaki Medical School General Medical Center ( Site 1412)
  • Osaka Metropolitan University Hospital ( Site 1415)
  • Toranomon Hospital ( Site 1401)
  • Seoul National University Bundang Hospital-Internal Medicine ( Site 2005)
  • Pusan National University Hospital-Internal Medicine ( Site 2010)
  • Chungang University Hospital ( Site 2007)
  • Asan Medical Center ( Site 2001)
  • Inha University Hospital-Gastroenterolgy/Hepatology ( Site 2006)
  • Seoul National University Hospital ( Site 2003)
  • Hanyang University Seoul Hospital ( Site 2002)
  • Samsung Medical Center-Gastroenterology/Internal Medicine ( Site 2008)
  • Korea University Guro Hospital ( Site 2004)
  • Hospital Kuala Lumpur-Gastroenterology Department ( Site 2701)
  • Medica Sur-Clinica de Enfermedades Digestivas y Obesidad ( Site 1515)
  • Centro de Investigacion Medico Biologica y Terapia Avanzada SC ( Site 1511)
  • Centro de Investigacion Medica de Occidente S.C. ( Site 1514)
  • Medical Care and Research S.A. de C.V. ( Site 1506)
  • Centro de Investigacion y Gastroenterologia SC ( Site 1503)
  • Christchurch Hospital ( Site 1602)
  • Auckland Clinical Studies Limited ( Site 1600)
  • Middlemore Clinical Trials ( Site 1601)
  • Pan American Center for Oncology Trials ( Site 3102)
  • Klinical Investigations Group ( Site 3100)
  • FDI Clinical Research ( Site 3101)
  • City Clinical Hospital named V.M.Buyanova ( Site 1922)
  • Russian University of People Friendship ( Site 1907)
  • Nephrology Clinic of Internal and Prof. Diseases n.a.E.M.Tareev ( Site 1906)
  • Center targetnoy therapy-Gastroenterology ( Site 1918)
  • Medical Rehabilitation Center ( Site 1904)
  • Scientific research center ECO-security ( Site 1920)
  • Surgical Clinic "Parada" ( Site 1921)
  • LLC Astarta ( Site 1912)
  • SPb State Budgetary Institution Health Care City Policlinic 17 ( Site 1910)
  • Hospital Universitario Marqués de Valdecilla-Gastroenterology and Hepatology ( Site 2106)
  • Hospital Clinico Universitario de Santiago ( Site 2104)
  • Hospital Universitario Puerta de Hierro-Majadahonda ( Site 2100)
  • Hospital Universitario Virgen del Rocio ( Site 2105)
  • Hospital Universitari Vall d Hebron ( Site 2101)
  • Hospital Clinic de Barcelona ( Site 2102)
  • Karolinska Universitetssjukhuset Huddinge ( Site 2900)
  • Akademiska sjukhuset ( Site 2901)
  • Chiayi Christian Hospital ( Site 2308)
  • Chung Shan Medical University Hospital ( Site 2307)
  • Chang Gung Memorial Hospital - Linkou Branch ( Site 2305)
  • Kaohsiung Medical University Chung-Ho Memorial Hospital ( Site 2302)
  • Taichung Veterans General Hospital ( Site 2306)
  • National Cheng Kung University Hospital ( Site 2304)
  • National Taiwan University Hospital ( Site 2301)
  • Hacettepe Uni. Ic Hastaliklari Anabilim Dali, Nefroloji BD ( Site 2403)
  • Gazi University Medical Faculty ( Site 2405)
  • Ankara University Cebeci Research and Application Hospital ( Site 2406)
  • Bezmialem Vakf Üniversitesi-Gastroenterology ( Site 2402)
  • Istanbul Universitesi Tip Fakultesi Hastanesi ( Site 2401)
  • Marmara Universitesi Pendik Egitim ve Arastirma Hastanesi ( Site 2400)
  • Ege University Medical Faculty ( Site 2404)

Arms of the Study

Arm 1

Arm 2

Arm 3

Arm 4

Arm Type

Experimental

Experimental

Experimental

Placebo Comparator

Arm Label

MK-3655 Low Dose

MK-3655 Middle Dose

MK-3655 High Dose

Placebo

Arm Description

MK-3655 low dose by subcutaneous (sc) injection once every 4 weeks (Q4W).

MK-3655 middle dose by sc injection Q4W.

MK-3655 high dose by sc injection Q4W.

Matching placebo to MK-3655 by sc injection Q4W.

Outcomes

Primary Outcome Measures

Percentage of Participants With Nonalcoholic Steatohepatitis (NASH) Resolution Without Worsening of Fibrosis After 52 Weeks
The NASH Clinical Research Network (CRN) scoring system evaluated by Blinded Independent Central Review (BICR) is used to assess treatment response. The NASH CRN scoring scales are: lobular inflammation score (0-3); hepatocyte ballooning score (0-2); steatosis score (0-3); and fibrosis score (0-4). NASH resolution is defined as a score of 0-1 for inflammation, 0 for ballooning, and any grade of steatosis.
Percentage of Participants Who Experienced an Adverse Event (AE)
An adverse event (AE) is defined as any unfavorable and unintended sign including an abnormal laboratory finding, symptom or disease associated with the use of a medical treatment or procedure, regardless of whether it is considered related to the medical treatment or procedure, that occurs during the course of the study.
Percentage of Participants Discontinuing Study Medication Due to an AE
An adverse event (AE) is defined as any unfavorable and unintended sign including an abnormal laboratory finding, symptom or disease associated with the use of a medical treatment or procedure, regardless of whether it is considered related to the medical treatment or procedure, that occurs during the course of the study.

Secondary Outcome Measures

Mean Percent Change from Baseline in Liver Fat Content (LFC) After 24 Weeks
LFC % is measured by Magnetic Resonance Imaging-Estimated Proton Density Fat Fraction (MRI-PDFF) and evaluated by BICR. MRI-PDFF is a highly accurate noninvasive measure of the proportion of fat content of a tissue.
Percentage of Participants With ≥1 Stage Improvement in Fibrosis Without Worsening of Steatohepatitis Assessed With the NASH CRN Scoring System After 52 Weeks
Participants evaluated with the NASH CRN scoring system with BICR with ≥1 stage improvement in fibrosis without worsening of steatohepatitis defined as no increase in the ballooning, inflammation, or steatosis scores.
Percentage of Participants With ≥2 Point Improvement in the Nonalcoholic Fatty Liver Disease Activity Score (NAS) Without Worsening of Fibrosis After 52 Weeks
Participants with ≥2 point improvement in the NAS with ≥1 point improvement in inflammation or ballooning without worsening of fibrosis assessed with the NASH CRN scoring system (evaluated by BICR). The NAS is calculated as the unweighted sum of the scores and ranges from 0-8 (highest activity).

Full Information

First Posted
October 5, 2020
Last Updated
April 24, 2023
Sponsor
Merck Sharp & Dohme LLC
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1. Study Identification

Unique Protocol Identification Number
NCT04583423
Brief Title
A Study of MK-3655 in Individuals With Pre-cirrhotic Nonalcoholic Steatohepatitis (NASH) (MK-3655-001)
Official Title
A Phase 2b Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of MK-3655 in Individuals With Pre-cirrhotic Nonalcoholic Steatohepatitis.
Study Type
Interventional

2. Study Status

Record Verification Date
April 2023
Overall Recruitment Status
Terminated
Why Stopped
Business reasons
Study Start Date
November 11, 2020 (Actual)
Primary Completion Date
April 13, 2023 (Actual)
Study Completion Date
April 13, 2023 (Actual)

3. Sponsor/Collaborators

Responsible Party, by Official Title
Sponsor
Name of the Sponsor
Merck Sharp & Dohme LLC

4. Oversight

Studies a U.S. FDA-regulated Drug Product
Yes
Studies a U.S. FDA-regulated Device Product
No
Data Monitoring Committee
Yes

5. Study Description

Brief Summary
This study will evaluate the effect of each dose of MK-3655 versus placebo on the percentage of individuals with NASH resolution without worsening of fibrosis after 52 weeks. The primary hypothesis of the study is that at least 1 dose of MK-3655 is superior to placebo with respect to the percentage of individuals with NASH resolution without worsening of fibrosis after 52 weeks.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Nonalcoholic Steatohepatitis
Keywords
Non-alcoholic fatty liver disease

7. Study Design

Primary Purpose
Treatment
Study Phase
Phase 2
Interventional Study Model
Parallel Assignment
Masking
ParticipantCare ProviderInvestigatorOutcomes Assessor
Allocation
Randomized
Enrollment
187 (Actual)

8. Arms, Groups, and Interventions

Arm Title
MK-3655 Low Dose
Arm Type
Experimental
Arm Description
MK-3655 low dose by subcutaneous (sc) injection once every 4 weeks (Q4W).
Arm Title
MK-3655 Middle Dose
Arm Type
Experimental
Arm Description
MK-3655 middle dose by sc injection Q4W.
Arm Title
MK-3655 High Dose
Arm Type
Experimental
Arm Description
MK-3655 high dose by sc injection Q4W.
Arm Title
Placebo
Arm Type
Placebo Comparator
Arm Description
Matching placebo to MK-3655 by sc injection Q4W.
Intervention Type
Drug
Intervention Name(s)
MK-3655
Other Intervention Name(s)
NGM313
Intervention Description
MK-3655 low, middle, or high dose for injection
Intervention Type
Drug
Intervention Name(s)
Placebo
Intervention Description
Matching placebo to MK-3655
Primary Outcome Measure Information:
Title
Percentage of Participants With Nonalcoholic Steatohepatitis (NASH) Resolution Without Worsening of Fibrosis After 52 Weeks
Description
The NASH Clinical Research Network (CRN) scoring system evaluated by Blinded Independent Central Review (BICR) is used to assess treatment response. The NASH CRN scoring scales are: lobular inflammation score (0-3); hepatocyte ballooning score (0-2); steatosis score (0-3); and fibrosis score (0-4). NASH resolution is defined as a score of 0-1 for inflammation, 0 for ballooning, and any grade of steatosis.
Time Frame
Week 52
Title
Percentage of Participants Who Experienced an Adverse Event (AE)
Description
An adverse event (AE) is defined as any unfavorable and unintended sign including an abnormal laboratory finding, symptom or disease associated with the use of a medical treatment or procedure, regardless of whether it is considered related to the medical treatment or procedure, that occurs during the course of the study.
Time Frame
Up to 56 weeks
Title
Percentage of Participants Discontinuing Study Medication Due to an AE
Description
An adverse event (AE) is defined as any unfavorable and unintended sign including an abnormal laboratory finding, symptom or disease associated with the use of a medical treatment or procedure, regardless of whether it is considered related to the medical treatment or procedure, that occurs during the course of the study.
Time Frame
Up to 52 weeks
Secondary Outcome Measure Information:
Title
Mean Percent Change from Baseline in Liver Fat Content (LFC) After 24 Weeks
Description
LFC % is measured by Magnetic Resonance Imaging-Estimated Proton Density Fat Fraction (MRI-PDFF) and evaluated by BICR. MRI-PDFF is a highly accurate noninvasive measure of the proportion of fat content of a tissue.
Time Frame
Baseline and Week 24
Title
Percentage of Participants With ≥1 Stage Improvement in Fibrosis Without Worsening of Steatohepatitis Assessed With the NASH CRN Scoring System After 52 Weeks
Description
Participants evaluated with the NASH CRN scoring system with BICR with ≥1 stage improvement in fibrosis without worsening of steatohepatitis defined as no increase in the ballooning, inflammation, or steatosis scores.
Time Frame
Week 52
Title
Percentage of Participants With ≥2 Point Improvement in the Nonalcoholic Fatty Liver Disease Activity Score (NAS) Without Worsening of Fibrosis After 52 Weeks
Description
Participants with ≥2 point improvement in the NAS with ≥1 point improvement in inflammation or ballooning without worsening of fibrosis assessed with the NASH CRN scoring system (evaluated by BICR). The NAS is calculated as the unweighted sum of the scores and ranges from 0-8 (highest activity).
Time Frame
Week 52

10. Eligibility

Sex
All
Minimum Age & Unit of Time
18 Years
Maximum Age & Unit of Time
80 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria: Has histological confirmation of NASH Is a male or female aged 18 years to 80 years (in Japan and Taiwan aged 20 to 80 years) Has a body mass index (BMI) ≥25 kg/m^2 and ≤50 kg/m^2 and stable weight for the past 3 months Has no history of Type 2 diabetes mellitus (T2DM) OR a history of T2DM controlled by diet or stable doses of antihyperglycemic agents (AHAs) Contraceptive use by male participants should be consistent with local regulations. A female participant is eligible to participate if she is not pregnant or breastfeeding, and she is not a woman of child-bearing potential (WOCBP) OR she is a WOCBP and uses a contraceptive method that is highly effective during the intervention period and for at least 16 weeks after the last dose of study intervention. Exclusion Criteria Has presence of cirrhosis on liver biopsy Has Type 1 diabetes Has a history of malignancy, unless cancer free ≥5 years, or is under evaluation for active or suspected malignancy except for adequately treated basal cell or squamous cell skin cancer or in situ cervical cancer Has a history of bariatric surgery ≤5 years before study participation Has undergone a major surgical procedure ≤3 months before study participation or has major surgery planned during the study Has a history or evidence of chronic liver disease other than NASH. Individuals with a history of Hepatitis B or C may be eligible for participation. Has significant systemic or major illnesses other than liver disease, including recent events (≤6 months before study entry) of congestive heart failure, unstable coronary artery disease, arterial revascularization, pulmonary disease, renal failure, stroke, transient ischemic attack, or organ transplantation
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Medical Director, MD
Organizational Affiliation
Merck Sharp & Dohme LLC
Official's Role
Study Director
Facility Information:
Facility Name
Adobe Clinical Research, LLC ( Site 2644)
City
Tucson
State/Province
Arizona
ZIP/Postal Code
85712
Country
United States
Facility Name
Arizona Liver Health ( Site 9026)
City
Tucson
State/Province
Arizona
ZIP/Postal Code
85712
Country
United States
Facility Name
Del Sol Research Management ( Site 2674)
City
Tucson
State/Province
Arizona
ZIP/Postal Code
85715
Country
United States
Facility Name
Arkansas Gastroenterology - North Little Rock ( Site 9015)
City
North Little Rock
State/Province
Arkansas
ZIP/Postal Code
72117
Country
United States
Facility Name
Hope Clinical Research, Inc. ( Site 2601)
City
Canoga Park
State/Province
California
ZIP/Postal Code
91303
Country
United States
Facility Name
Velocity Clinical Research, Huntington Park ( Site 9022)
City
Huntington Park
State/Province
California
ZIP/Postal Code
90255
Country
United States
Facility Name
UCSD - Altman Clinical and Translational Research Institute -UC San Diego NAFLD Research Center ( Si
City
La Jolla
State/Province
California
ZIP/Postal Code
92037
Country
United States
Facility Name
Ruane Clinical Research Group, Inc ( Site 9014)
City
Los Angeles
State/Province
California
ZIP/Postal Code
90036
Country
United States
Facility Name
Velocity Clinical Research, Westlake ( Site 9013)
City
Los Angeles
State/Province
California
ZIP/Postal Code
90057
Country
United States
Facility Name
Catalina Research Institute, LLC ( Site 2643)
City
Montclair
State/Province
California
ZIP/Postal Code
91763
Country
United States
Facility Name
Velocity Clinical Research, Panorama City ( Site 9001)
City
Panorama City
State/Province
California
ZIP/Postal Code
91402
Country
United States
Facility Name
California Liver Research Institute ( Site 9025)
City
Pasadena
State/Province
California
ZIP/Postal Code
91105
Country
United States
Facility Name
Quest Clinical Research ( Site 9011)
City
San Francisco
State/Province
California
ZIP/Postal Code
94115
Country
United States
Facility Name
Velocity Clinical Research, Santa Ana ( Site 9002)
City
Santa Ana
State/Province
California
ZIP/Postal Code
92704
Country
United States
Facility Name
Peak Gastroenterology Associates ( Site 2645)
City
Colorado Springs
State/Province
Colorado
ZIP/Postal Code
80920
Country
United States
Facility Name
Top Medical Research, Inc ( Site 2673)
City
Cutler Bay
State/Province
Florida
ZIP/Postal Code
33189
Country
United States
Facility Name
Covenant Metabolic Specialists, LLC ( Site 9027)
City
Fort Myers
State/Province
Florida
ZIP/Postal Code
33912
Country
United States
Facility Name
North Florida South Georgia Veterans Health System ( Site 2613)
City
Gainesville
State/Province
Florida
ZIP/Postal Code
32608
Country
United States
Facility Name
Indago Research and Health Center Inc ( Site 2610)
City
Hialeah
State/Province
Florida
ZIP/Postal Code
33012
Country
United States
Facility Name
Sweet Hope Research Specialty Inc ( Site 2660)
City
Hialeah
State/Province
Florida
ZIP/Postal Code
33016
Country
United States
Facility Name
Floridian Clinical Research, LLC ( Site 2656)
City
Miami Lakes
State/Province
Florida
ZIP/Postal Code
33016-1518
Country
United States
Facility Name
Ocean Blue Medical Research Center Inc ( Site 2667)
City
Miami Springs
State/Province
Florida
ZIP/Postal Code
33166
Country
United States
Facility Name
Genoma Research Group, Inc. ( Site 2669)
City
Miami
State/Province
Florida
ZIP/Postal Code
33173
Country
United States
Facility Name
Sensible Healthcare Llc ( Site 2607)
City
Ocoee
State/Province
Florida
ZIP/Postal Code
34761
Country
United States
Facility Name
Synexus Research ( Site 2672)
City
Orlando
State/Province
Florida
ZIP/Postal Code
32806
Country
United States
Facility Name
Southeast Clinical Research Center ( Site 9003)
City
Dalton
State/Province
Georgia
ZIP/Postal Code
30720
Country
United States
Facility Name
The University of Iowa ( Site 2655)
City
Iowa City
State/Province
Iowa
ZIP/Postal Code
52242
Country
United States
Facility Name
Legacy Clinical Solutions: Tandem Clinical Research, LLC ( Site 2650)
City
Marrero
State/Province
Louisiana
ZIP/Postal Code
70072
Country
United States
Facility Name
The National Diabetes & Obesity Research Institute ( Site 9017)
City
Biloxi
State/Province
Mississippi
ZIP/Postal Code
39532
Country
United States
Facility Name
Kansas City Research Institute ( Site 9018)
City
Kansas City
State/Province
Missouri
ZIP/Postal Code
64131
Country
United States
Facility Name
Excel Clinical Research, LLC ( Site 2603)
City
Las Vegas
State/Province
Nevada
ZIP/Postal Code
89109
Country
United States
Facility Name
Velocity Clinical Research, Syracuse ( Site 9016)
City
East Syracuse
State/Province
New York
ZIP/Postal Code
13057
Country
United States
Facility Name
NYU Langone Health, New York ( Site 2627)
City
New York
State/Province
New York
ZIP/Postal Code
10016
Country
United States
Facility Name
Hillmont G.I. ( Site 9019)
City
Flourtown
State/Province
Pennsylvania
ZIP/Postal Code
19031
Country
United States
Facility Name
Regional Gastroenterology Associates of Lancaster, LTD ( Site 9020)
City
Lancaster
State/Province
Pennsylvania
ZIP/Postal Code
17601
Country
United States
Facility Name
Regional Gastroenterology Associates of Lancaster, LTD ( Site 9004)
City
Wyomissing
State/Province
Pennsylvania
ZIP/Postal Code
19610
Country
United States
Facility Name
Premier Medical Group ( Site 9010)
City
Clarksville
State/Province
Tennessee
ZIP/Postal Code
37040
Country
United States
Facility Name
Texas Clinical Research Institute ( Site 2619)
City
Arlington
State/Province
Texas
ZIP/Postal Code
76012
Country
United States
Facility Name
The Liver Institute at Methodist Dallas Medical Center ( Site 2638)
City
Dallas
State/Province
Texas
ZIP/Postal Code
75203
Country
United States
Facility Name
DHR Health Institute for Research and Development ( Site 9006)
City
Edinburg
State/Province
Texas
ZIP/Postal Code
78539
Country
United States
Facility Name
South Texas Research Institute ( Site 9012)
City
Edinburg
State/Province
Texas
ZIP/Postal Code
78539
Country
United States
Facility Name
Baylor College of Medicine - Advanced Liver Therapies ( Site 2670)
City
Houston
State/Province
Texas
ZIP/Postal Code
77030
Country
United States
Facility Name
The Crofoot Research Center, Inc. ( Site 2611)
City
Houston
State/Province
Texas
ZIP/Postal Code
77098
Country
United States
Facility Name
Quality Research ( Site 9024)
City
San Antonio
State/Province
Texas
ZIP/Postal Code
78209
Country
United States
Facility Name
American Research Corporation at Texas Liver Institute ( Site 2634)
City
San Antonio
State/Province
Texas
ZIP/Postal Code
78215
Country
United States
Facility Name
Clinical Trials of Texas, LLC ( Site 2614)
City
San Antonio
State/Province
Texas
ZIP/Postal Code
78229
Country
United States
Facility Name
Impact Research Institute ( Site 2685)
City
Waco
State/Province
Texas
ZIP/Postal Code
76710
Country
United States
Facility Name
Virginia Commonwealth University Health System ( Site 2657)
City
Richmond
State/Province
Virginia
ZIP/Postal Code
23298
Country
United States
Facility Name
Instituto de Investigaciones Clínicas Mar del Plata ( Site 0010)
City
Mar del Plata
State/Province
Buenos Aires
ZIP/Postal Code
7600
Country
Argentina
Facility Name
Hospital Universitario Austral ( Site 0003)
City
Pilar
State/Province
Buenos Aires
ZIP/Postal Code
B1629AHJ
Country
Argentina
Facility Name
DIM Clínica Privada ( Site 0011)
City
Ramos Mejía
State/Province
Buenos Aires
ZIP/Postal Code
1704
Country
Argentina
Facility Name
Hospital Británico de Buenos Aires ( Site 0002)
City
Buenos Aires
State/Province
Caba
ZIP/Postal Code
1280
Country
Argentina
Facility Name
Glenny Corp. S.A.-CLINICAL RESEARCH ( Site 0013)
City
Buenos Aires
State/Province
Caba
ZIP/Postal Code
C1430CKE
Country
Argentina
Facility Name
Hospital Italiano de Buenos Aires-Hepatology ( Site 0014)
City
Ciudad de Buenos Aires
State/Province
Caba
ZIP/Postal Code
C1199ABB
Country
Argentina
Facility Name
Hospital Provincial del Centenario ( Site 0007)
City
Rosario
State/Province
Santa Fe
ZIP/Postal Code
S2002KDS
Country
Argentina
Facility Name
Hospital Aleman ( Site 0009)
City
Buenos Aires
ZIP/Postal Code
C1118AAT
Country
Argentina
Facility Name
Clinica de nefrologia urologia y enfermedades cardiovasculares ( Site 0008)
City
Santa Fe
ZIP/Postal Code
S3000BPJ
Country
Argentina
Facility Name
Royal Prince Alfred Hospital ( Site 0102)
City
Camperdown
State/Province
New South Wales
ZIP/Postal Code
2050
Country
Australia
Facility Name
St George Hospital ( Site 0104)
City
Kogarah
State/Province
New South Wales
ZIP/Postal Code
2217
Country
Australia
Facility Name
Flinders Medical Centre ( Site 0107)
City
Bedford Park
State/Province
South Australia
ZIP/Postal Code
5042
Country
Australia
Facility Name
GIRI GI Research Institute - Vancouver ( Site 0404)
City
Vancouver
State/Province
British Columbia
ZIP/Postal Code
V5Z 2K5
Country
Canada
Facility Name
University Health Network - Toronto General Hospital ( Site 0401)
City
Toronto
State/Province
Ontario
ZIP/Postal Code
M5G 2C4
Country
Canada
Facility Name
McGill University Health Centre ( Site 0400)
City
Montréal
State/Province
Quebec
ZIP/Postal Code
H4A 3J1
Country
Canada
Facility Name
Hospital Regional de Concepcion ( Site 0505)
City
Concepcion
State/Province
Biobio
ZIP/Postal Code
4070038
Country
Chile
Facility Name
Hospital San Juan de Dios de La Serena ( Site 0500)
City
La Serena
State/Province
Coquimbo
ZIP/Postal Code
1710216
Country
Chile
Facility Name
Clinical Research Chile SpA ( Site 0506)
City
Valdivia
State/Province
Los Rios
ZIP/Postal Code
5110683
Country
Chile
Facility Name
Enroll SpA ( Site 0508)
City
Santiago
State/Province
Region M. De Santiago
ZIP/Postal Code
7500587
Country
Chile
Facility Name
Pontificia Universidad Catolica de Chile ( Site 0501)
City
Santiago
State/Province
Region M. De Santiago
ZIP/Postal Code
8330077
Country
Chile
Facility Name
Centro de Investigaciones Clinicas Vina del Mar ( Site 0502)
City
Vina del Mar
State/Province
Valparaiso
ZIP/Postal Code
2540488
Country
Chile
Facility Name
Beijing YouAn Hospital, Capital Medical University ( Site 0605)
City
Beijing
State/Province
Beijing
ZIP/Postal Code
100069
Country
China
Facility Name
Chongqing Three Gorges Central Hospital ( Site 0618)
City
Wanzhou District
State/Province
Chongqing
ZIP/Postal Code
404100
Country
China
Facility Name
The First People's Hospital of Foshan-Infection Department ( Site 0612)
City
Foshan
State/Province
Guangdong
ZIP/Postal Code
528041
Country
China
Facility Name
General Hospital of Ningxia Medical University ( Site 0607)
City
Yinchuan City
State/Province
Ningxia
ZIP/Postal Code
750004
Country
China
Facility Name
Xinhua Hospital Affiliated to Jiaotong University School of Medicine ( Site 0602)
City
Shanghai
State/Province
Shanghai
ZIP/Postal Code
200092
Country
China
Facility Name
The Affiliated Hospital of Hangzhou Normal University ( Site 0600)
City
Hangzhou
State/Province
Zhejiang
ZIP/Postal Code
310015
Country
China
Facility Name
Fundacion Santa Fe de Bogota ( Site 0705)
City
Bogotá
State/Province
Distrito Capital De Bogota
ZIP/Postal Code
110111
Country
Colombia
Facility Name
CHU de Nice Hopital de l Archet II ( Site 0800)
City
Nice
State/Province
Alpes-Maritimes
ZIP/Postal Code
06202
Country
France
Facility Name
hopital haut leveque chu de bordeaux-Service d'Hépato-gastroentérologie ( Site 0805)
City
Pessac
State/Province
Aquitaine
ZIP/Postal Code
33600
Country
France
Facility Name
Hopital de la Croix-Rousse ( Site 0809)
City
Lyon
State/Province
Auvergne
ZIP/Postal Code
69004
Country
France
Facility Name
CHU Dijon Bourgogne - Hopital F. Mitterrand ( Site 0816)
City
Dijon
State/Province
Bourgogne
ZIP/Postal Code
21079
Country
France
Facility Name
CHU Besançon ( Site 0806)
City
Besançon
State/Province
Franche-Comte
ZIP/Postal Code
25000
Country
France
Facility Name
Centre Hospitalier et Universitaire Dupuytren ( Site 0810)
City
Limoges
State/Province
Haute-Vienne
ZIP/Postal Code
87042
Country
France
Facility Name
Hôpital Beaujon ( Site 0804)
City
Clichy
State/Province
Hauts-de-Seine
ZIP/Postal Code
92110
Country
France
Facility Name
C.H.U. Nancy Hopital de Brabois ( Site 0803)
City
Vandoeuvre les Nancy
State/Province
Meurthe-et-Moselle
ZIP/Postal Code
54500
Country
France
Facility Name
Hôpital Claude Huriez ( Site 0811)
City
Lille
State/Province
Nord
ZIP/Postal Code
59037
Country
France
Facility Name
Hopital Henri Mondor ( Site 0808)
City
Creteil
State/Province
Val-de-Marne
ZIP/Postal Code
94000
Country
France
Facility Name
A.P.H. Paris, Hopital Saint Antoine ( Site 0807)
City
Paris
ZIP/Postal Code
75012
Country
France
Facility Name
Hopital de la Pitie Salpetriere ( Site 0813)
City
Paris
ZIP/Postal Code
75013
Country
France
Facility Name
Hopitaux Universitaires Paris Centre-Hopital Cochin ( Site 0812)
City
Paris
ZIP/Postal Code
75679
Country
France
Facility Name
Universitaetsklinikum Freiburg ( Site 0446)
City
Freiburg
State/Province
Baden-Wurttemberg
ZIP/Postal Code
79106
Country
Germany
Facility Name
Universitätsklinikum Frankfurt-Medizinische Klinik 1 ( Site 0445)
City
Frankfurt
State/Province
Hessen
ZIP/Postal Code
60590
Country
Germany
Facility Name
Johannes Gutenberg Universitat Mainz ( Site 0442)
City
Mainz
State/Province
Rheinland-Pfalz
ZIP/Postal Code
55131
Country
Germany
Facility Name
Universitaetsklinikum Leipzig ( Site 0447)
City
Leipzig
State/Province
Sachsen
ZIP/Postal Code
04103
Country
Germany
Facility Name
Charite Universitaetsmedizin Berlin ( Site 0443)
City
Berlin
ZIP/Postal Code
13353
Country
Germany
Facility Name
Hippokration University Hopsital-4th Department of Internal Medicine ( Site 3300)
City
Thessaloniki
State/Province
Kentriki Makedonia
ZIP/Postal Code
5 46 42
Country
Greece
Facility Name
Queen Mary Hospital ( Site 1003)
City
Hong Kong
ZIP/Postal Code
000000
Country
Hong Kong
Facility Name
Prince of Wales Hospital ( Site 1001)
City
Shatin
Country
Hong Kong
Facility Name
Prince of Wales Hospital ( Site 1002)
City
Shatin
Country
Hong Kong
Facility Name
Rambam Medical Center ( Site 1201)
City
Haifa
ZIP/Postal Code
3109601
Country
Israel
Facility Name
Carmel Medical Center ( Site 1203)
City
Haifa
ZIP/Postal Code
3436212
Country
Israel
Facility Name
Shaare Zedek Medical Center ( Site 1205)
City
Jerusalem
ZIP/Postal Code
9132201
Country
Israel
Facility Name
Rabin Medical Center ( Site 1204)
City
Petah Tikva
ZIP/Postal Code
4941492
Country
Israel
Facility Name
Chaim Sheba Medical Center ( Site 1200)
City
Ramat Gan
ZIP/Postal Code
5265601
Country
Israel
Facility Name
Maccabi Health Services - Ramat Hasharon ( Site 1206)
City
Ramat Hasharon
ZIP/Postal Code
4731001
Country
Israel
Facility Name
Sourasky Medical Center ( Site 1202)
City
Tel Aviv
ZIP/Postal Code
6423906
Country
Israel
Facility Name
IRCCS Istituto Clinico Humanitas di Rozzano ( Site 1303)
City
Rozzano
State/Province
Lombardia
ZIP/Postal Code
20089
Country
Italy
Facility Name
A O U Policlinico di Modena ( Site 1307)
City
Modena
ZIP/Postal Code
41124
Country
Italy
Facility Name
Azienda Ospedaliera Policlinico Umberto I ( Site 1300)
City
Roma
ZIP/Postal Code
00161
Country
Italy
Facility Name
Azienda Ospedaliera Universitaria Integrata Verona ( Site 1301)
City
Verona
ZIP/Postal Code
37134
Country
Italy
Facility Name
Aichi Medical University Hospital ( Site 1402)
City
Nagakute
State/Province
Aichi
ZIP/Postal Code
480-1195
Country
Japan
Facility Name
Ehime University Hospital ( Site 1417)
City
Toon
State/Province
Ehime
ZIP/Postal Code
791-0295
Country
Japan
Facility Name
Ogaki Municipal Hospital ( Site 1409)
City
Ogaki
State/Province
Gifu
ZIP/Postal Code
503-8502
Country
Japan
Facility Name
Hokkaido P.W.F.A.C Sapporo-Kosei General Hospital ( Site 1404)
City
Sapporo
State/Province
Hokkaido
ZIP/Postal Code
060-0033
Country
Japan
Facility Name
Kanazawa University Hospital ( Site 1419)
City
Kanazawa
State/Province
Ishikawa
ZIP/Postal Code
920-8641
Country
Japan
Facility Name
Kagawa University Hospital ( Site 1414)
City
Kita-gun
State/Province
Kagawa
ZIP/Postal Code
761-0793
Country
Japan
Facility Name
Kagawa Prefectural Central Hospital-liver intemal medicine ( Site 1416)
City
Takamatsu
State/Province
Kagawa
ZIP/Postal Code
760-0065
Country
Japan
Facility Name
Shinyurigaoka General Hospital ( Site 1420)
City
Kawasaki
State/Province
Kanagawa
ZIP/Postal Code
215-0026
Country
Japan
Facility Name
Yokohama City University Hospital ( Site 1411)
City
Yokohama
State/Province
Kanagawa
ZIP/Postal Code
236-0004
Country
Japan
Facility Name
Nara Medical University Hospital ( Site 1407)
City
Kashihara
State/Province
Nara
ZIP/Postal Code
634-8522
Country
Japan
Facility Name
Saiseikai Suita Hospital ( Site 1403)
City
Suita
State/Province
Osaka
ZIP/Postal Code
564-0013
Country
Japan
Facility Name
Fukui-ken Saiseikai Hospital ( Site 1410)
City
Fukui
ZIP/Postal Code
918-8503
Country
Japan
Facility Name
Gifu Municipal Hospital ( Site 1408)
City
Gifu
ZIP/Postal Code
500-8513
Country
Japan
Facility Name
Hiroshima University Hospital ( Site 1413)
City
Hiroshima
ZIP/Postal Code
7348551
Country
Japan
Facility Name
Kagoshima University Hospital ( Site 1418)
City
Kagoshima
ZIP/Postal Code
890-8520
Country
Japan
Facility Name
University Hospital, Kyoto Prefectural University of Medicine ( Site 1405)
City
Kyoto
ZIP/Postal Code
602-8566
Country
Japan
Facility Name
Kawasaki Medical School General Medical Center ( Site 1412)
City
Okayama
ZIP/Postal Code
700-8505
Country
Japan
Facility Name
Osaka Metropolitan University Hospital ( Site 1415)
City
Osaka
ZIP/Postal Code
545-8586
Country
Japan
Facility Name
Toranomon Hospital ( Site 1401)
City
Tokyo
ZIP/Postal Code
105-8470
Country
Japan
Facility Name
Seoul National University Bundang Hospital-Internal Medicine ( Site 2005)
City
Seongnam
State/Province
Kyonggi-do
ZIP/Postal Code
13620
Country
Korea, Republic of
Facility Name
Pusan National University Hospital-Internal Medicine ( Site 2010)
City
Busan
State/Province
Pusan-Kwangyokshi
ZIP/Postal Code
49241
Country
Korea, Republic of
Facility Name
Chungang University Hospital ( Site 2007)
City
Dongjak-gu
State/Province
Seoul
ZIP/Postal Code
06973
Country
Korea, Republic of
Facility Name
Asan Medical Center ( Site 2001)
City
Songpagu
State/Province
Seoul
ZIP/Postal Code
05505
Country
Korea, Republic of
Facility Name
Inha University Hospital-Gastroenterolgy/Hepatology ( Site 2006)
City
Incheon
ZIP/Postal Code
22332
Country
Korea, Republic of
Facility Name
Seoul National University Hospital ( Site 2003)
City
Seoul
ZIP/Postal Code
03080
Country
Korea, Republic of
Facility Name
Hanyang University Seoul Hospital ( Site 2002)
City
Seoul
ZIP/Postal Code
04763
Country
Korea, Republic of
Facility Name
Samsung Medical Center-Gastroenterology/Internal Medicine ( Site 2008)
City
Seoul
ZIP/Postal Code
06351
Country
Korea, Republic of
Facility Name
Korea University Guro Hospital ( Site 2004)
City
Seoul
ZIP/Postal Code
08308
Country
Korea, Republic of
Facility Name
Hospital Kuala Lumpur-Gastroenterology Department ( Site 2701)
City
Kuala Lumpur
ZIP/Postal Code
50586
Country
Malaysia
Facility Name
Medica Sur-Clinica de Enfermedades Digestivas y Obesidad ( Site 1515)
City
Mexico City
State/Province
Distrito Federal
ZIP/Postal Code
14050
Country
Mexico
Facility Name
Centro de Investigacion Medico Biologica y Terapia Avanzada SC ( Site 1511)
City
Guadalajara
State/Province
Jalisco
ZIP/Postal Code
44130
Country
Mexico
Facility Name
Centro de Investigacion Medica de Occidente S.C. ( Site 1514)
City
Zapopan
State/Province
Jalisco
ZIP/Postal Code
45116
Country
Mexico
Facility Name
Medical Care and Research S.A. de C.V. ( Site 1506)
City
Merida
State/Province
Yucatan
ZIP/Postal Code
97070
Country
Mexico
Facility Name
Centro de Investigacion y Gastroenterologia SC ( Site 1503)
City
Mexico City
ZIP/Postal Code
06700
Country
Mexico
Facility Name
Christchurch Hospital ( Site 1602)
City
Christchurch
State/Province
Canterbury
ZIP/Postal Code
8011
Country
New Zealand
Facility Name
Auckland Clinical Studies Limited ( Site 1600)
City
Auckland
ZIP/Postal Code
1010
Country
New Zealand
Facility Name
Middlemore Clinical Trials ( Site 1601)
City
Auckland
ZIP/Postal Code
2025
Country
New Zealand
Facility Name
Pan American Center for Oncology Trials ( Site 3102)
City
Rio Piedras
ZIP/Postal Code
00935
Country
Puerto Rico
Facility Name
Klinical Investigations Group ( Site 3100)
City
San Juan
ZIP/Postal Code
00909
Country
Puerto Rico
Facility Name
FDI Clinical Research ( Site 3101)
City
San Juan
ZIP/Postal Code
00927
Country
Puerto Rico
Facility Name
City Clinical Hospital named V.M.Buyanova ( Site 1922)
City
Moscow
State/Province
Moskva
ZIP/Postal Code
115516
Country
Russian Federation
Facility Name
Russian University of People Friendship ( Site 1907)
City
Moscow
State/Province
Moskva
ZIP/Postal Code
117198
Country
Russian Federation
Facility Name
Nephrology Clinic of Internal and Prof. Diseases n.a.E.M.Tareev ( Site 1906)
City
Moscow
State/Province
Moskva
ZIP/Postal Code
119435
Country
Russian Federation
Facility Name
Center targetnoy therapy-Gastroenterology ( Site 1918)
City
Moscow
State/Province
Moskva
ZIP/Postal Code
125008
Country
Russian Federation
Facility Name
Medical Rehabilitation Center ( Site 1904)
City
Moscow
State/Province
Moskva
ZIP/Postal Code
125367
Country
Russian Federation
Facility Name
Scientific research center ECO-security ( Site 1920)
City
Saint Petersburg
State/Province
Sankt-Peterburg
ZIP/Postal Code
196143
Country
Russian Federation
Facility Name
Surgical Clinic "Parada" ( Site 1921)
City
Saint Petersburg
State/Province
Sankt-Peterburg
ZIP/Postal Code
197348
Country
Russian Federation
Facility Name
LLC Astarta ( Site 1912)
City
Saint Petersburg
State/Province
Sankt-Peterburg
ZIP/Postal Code
199226
Country
Russian Federation
Facility Name
SPb State Budgetary Institution Health Care City Policlinic 17 ( Site 1910)
City
St -Petersburg
State/Province
Sankt-Peterburg
ZIP/Postal Code
194358
Country
Russian Federation
Facility Name
Hospital Universitario Marqués de Valdecilla-Gastroenterology and Hepatology ( Site 2106)
City
Santander
State/Province
Cantabria
ZIP/Postal Code
39005
Country
Spain
Facility Name
Hospital Clinico Universitario de Santiago ( Site 2104)
City
Santiago de Compostela
State/Province
La Coruna
ZIP/Postal Code
15706
Country
Spain
Facility Name
Hospital Universitario Puerta de Hierro-Majadahonda ( Site 2100)
City
Majadahonda
State/Province
Madrid
ZIP/Postal Code
28222
Country
Spain
Facility Name
Hospital Universitario Virgen del Rocio ( Site 2105)
City
Sevila
State/Province
Sevilla
ZIP/Postal Code
41013
Country
Spain
Facility Name
Hospital Universitari Vall d Hebron ( Site 2101)
City
Barcelona
ZIP/Postal Code
08035
Country
Spain
Facility Name
Hospital Clinic de Barcelona ( Site 2102)
City
Barcelona
ZIP/Postal Code
08036
Country
Spain
Facility Name
Karolinska Universitetssjukhuset Huddinge ( Site 2900)
City
Huddinge
State/Province
Stockholms Lan
ZIP/Postal Code
141 86
Country
Sweden
Facility Name
Akademiska sjukhuset ( Site 2901)
City
Uppsala
State/Province
Uppsala Lan
ZIP/Postal Code
751 85
Country
Sweden
Facility Name
Chiayi Christian Hospital ( Site 2308)
City
Chiayi City
State/Province
Chiayi
ZIP/Postal Code
600
Country
Taiwan
Facility Name
Chung Shan Medical University Hospital ( Site 2307)
City
Taichung City
State/Province
Taichung
ZIP/Postal Code
402
Country
Taiwan
Facility Name
Chang Gung Memorial Hospital - Linkou Branch ( Site 2305)
City
Taoyuan County
State/Province
Taoyuan
ZIP/Postal Code
333
Country
Taiwan
Facility Name
Kaohsiung Medical University Chung-Ho Memorial Hospital ( Site 2302)
City
Kaohsiung
ZIP/Postal Code
807
Country
Taiwan
Facility Name
Taichung Veterans General Hospital ( Site 2306)
City
Taichung
ZIP/Postal Code
407
Country
Taiwan
Facility Name
National Cheng Kung University Hospital ( Site 2304)
City
Tainan
ZIP/Postal Code
704
Country
Taiwan
Facility Name
National Taiwan University Hospital ( Site 2301)
City
Taipei
ZIP/Postal Code
100
Country
Taiwan
Facility Name
Hacettepe Uni. Ic Hastaliklari Anabilim Dali, Nefroloji BD ( Site 2403)
City
Ankara
ZIP/Postal Code
06230
Country
Turkey
Facility Name
Gazi University Medical Faculty ( Site 2405)
City
Ankara
ZIP/Postal Code
06560
Country
Turkey
Facility Name
Ankara University Cebeci Research and Application Hospital ( Site 2406)
City
Ankara
ZIP/Postal Code
54290
Country
Turkey
Facility Name
Bezmialem Vakf Üniversitesi-Gastroenterology ( Site 2402)
City
Istanbul
ZIP/Postal Code
34093
Country
Turkey
Facility Name
Istanbul Universitesi Tip Fakultesi Hastanesi ( Site 2401)
City
Istanbul
ZIP/Postal Code
34093
Country
Turkey
Facility Name
Marmara Universitesi Pendik Egitim ve Arastirma Hastanesi ( Site 2400)
City
Istanbul
ZIP/Postal Code
34899
Country
Turkey
Facility Name
Ege University Medical Faculty ( Site 2404)
City
Izmir
ZIP/Postal Code
35100
Country
Turkey

12. IPD Sharing Statement

Plan to Share IPD
Yes
IPD Sharing Plan Description
http://engagezone.msd.com/doc/ProcedureAccessClinicalTrialData.pdf
IPD Sharing URL
http://engagezone.msd.com/ds_documentation.php

Learn more about this trial

A Study of MK-3655 in Individuals With Pre-cirrhotic Nonalcoholic Steatohepatitis (NASH) (MK-3655-001)

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