Gut Microbiome and Sex as Risk Factors for Kidney Stones After Bariatric Surgery
Bariatric Surgery Candidate
About this trial
This is an interventional prevention trial for Bariatric Surgery Candidate focused on measuring bariatric surgery, kidney stones
Eligibility Criteria
Inclusion Criteria:
- Participants without history of stone disease, family history of stone disease
- Participants pre-bariatric surgery who are approved and planned for surgery in the Bariatric Surgery Center at University of Chicago Medicine.
Exclusion Criteria:
- Patients with primary renal diseases or renal impairment (eGFR < 90)
- Patients with known bladder voiding problems
- Patients with 25-vitamine D deficiency, as defined by level < 25ng/mL
Sites / Locations
- University of Chicago Medical CenterRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
Experimental
Roux-en-y gastric bypass subjects
Sleeve gastrectomy subjects
Inclusion Criteria: Age 18-70. Participants pre-Roux-en-y gastric bypass (RYGB) who are approved and planned for Roux-en-y gastric bypass surgery in the Bariatric Surgery Center at the UCM. Exclusion Criteria: Patients with primary kidney diseases, kidney stone disease, or kidney impairment (eGFR < 90). Patients with known bladder voiding problems. Participants will complete a diet record and a 24-hour urine collection both before and after surgery. Participants will consume a 3 day fixed diet and present to the clinical research center for timed blood and urine draws. They will do this before and twice after (1 month and 1 year) surgery.
Inclusion Criteria: Age 18-70. Participants pre-sleeve gastrectomy who are approved and sleeve gastrectomy in the Bariatric Surgery Center at the UCM. Exclusion Criteria: Patients with primary kidney diseases, kidney stone disease, or kidney impairment (eGFR < 90). Patients with known bladder voiding problems. Participants will complete a diet record and a 24-hour urine collection both before and after surgery. Participants will consume a 3 day fixed diet and present to the clinical research center for timed blood and urine draws. They will do this before and twice after (1 month and 1 year) surgery.