Back to resultsA Study to Evaluate Long Term Safety and Efficacy of Recombinant Human Pentraxin-2 (rhPTX-2; PRM-151) in Participants With Idiopathic Pulmonary Fibrosis (STARSCAPE-OLE)
Primary Purpose
Idiopathic Pulmonary Fibrosis
Status
Terminated
Phase
Phase 3
Locations
International
Study Type
Interventional
Intervention
PRM-151 (Zinpentraxin Alfa)
Sponsored by
About this trial
This is an interventional treatment trial for Idiopathic Pulmonary Fibrosis
Eligibility Criteria
Inclusion Criteria:
- Taken part in either of the prior PRM-151 studies: PRM-151-202 or WA42293.
- For women of childbearing potential: agreement to remain abstinent (refrain from heterosexual intercourse) or use contraception.
- For men: agreement to remain abstinent (refrain from heterosexual intercourse) or use a condom, and agreement to refrain from donating sperm.
Exclusion Criteria:
- Acute respiratory or systemic bacterial, viral, or fungal infection at the first visit of the OLE, or within 2 weeks of the first visit for patients joining Cohort A (from Study PRM-151-202).
- History of smoking within 3 months prior to the first visit in the OLE.
- History of alcohol or substance use disorder within 2 years prior to the first visit of the OLE or known or suspected active alcohol or substance-use disorder.
- History of severe allergic reaction or anaphylactic reaction to PRM-151.
- Clinically significant abnormality on ECG during eligibility assessment that, in the opinion of the investigator, may pose an additional risk in administering study drug to the participant.
- Prolonged corrected QT interval > 450 ms (for men) or > 470 ms (for women) based on the Fridericia correction formula.
- Clinically significant laboratory test abnormalities (hematology, serumchemistry, and urinalysis) that, in the opinion of the investigator, may pose an additional risk in administering study drug to the participant.
Sites / Locations
- University of Alabama at Birmingham
- University of California Davis
- Inst. of Healthcare Assessment, Inc.
- UCSF Medical Center
- National Jewish Health Medical Center
- Yale New Haven Hospital
- Georgetown University Medical Center
- Meris Clinical Research
- Florida Lung, Asthma and Sleep Specialists (FLASS) - Celebration
- Advanced Pulmonary & Sleep Research Institute of Florida
- University of Florida Health Pulmonology - Jacksonville
- Advanced Pulmonary Research Institute
- Sarasota County Public Hospital
- Renstar Medical Research
- Florida Pulmonary Research Institute, LLC
- NorthShore University HealthSystem
- University of Iowa Hospitals and Clinics; Investigational Drug Services
- University of Kansas Medical Center
- University of Louisville Health Sciences Center
- Massachusetts General Hospital
- University of Minnesota Medical Center
- Mayo Clinic Rochester
- The Lung Research Center
- Washington University
- University of Nebraska Medical Center
- Lenox Hill Hospital
- Pulmonix Research
- PMG Research of Wilmington
- Oregon Health and Science University
- Jefferson University Physicians (JUP) - Jefferson Pulmonary
- University of Pittsburgh Medical Center
- SleepMed of South Carolina
- Lowcountry Lung and Critical Care
- Spartanburg Medical Center
- Vanderbilt University Medical Center
- University of Texas Medical Branch at Galveston
- Metroplex Pulmonology & Sleep Center
- University Of Utah Hosp & Clin; Investigational Pharmacy
- Inova Fairfax Hospital
- Virginia Commonwealth University
- Hospital Britanico de Buenos Aires
- Fundacion Respirar (Centro Medico Dra. De Salvo)
- Instituto de Medicina Respiratoria, IMeR; Clinic/Outpatient Facility
- Hospital Universitario Austral
- Centro Medico de Enfermedades Respiratorias (CEMER)
- Centro de estudios respiratorios
- INSARES
- Fundacion Scherbovsky
- Instituto Medico de la Fundacion Estudios Clinicos
- Investigaciones en Patologias Respiratorias
- Royal Prince Alfred Hospital
- Cairns Base Hospital; Cancer Care Centre
- Lung Research Queensland
- Princess Alexandra Hospital
- Monash Medical Centre; Medicine
- The Alfred Hospital
- ULB Hôpital Erasme
- Cliniques Universitaires Saint-Luc; Pharmacy
- UZ Leuven
- C. H. U. Sart-Tilman; Laboratory
- CHU UCL Namur / site Godinne
- Synergy Respiratory Care
- Kelowna Respiratory and Allergy Clinic
- The Rhema Research Institute
- Dr. Syed Anees Medicine Profession Corporation
- C.I.C. Mauricie
- Peking Union Medical College Hospital; Pharmacy
- Beijing Friendship Hospital Affiliated of Capital University of Medical Science
- The Second Xiangya Hospital of Central South University
- The Third Xiangya Hospital Of Central South University
- Shengjing Hospital of China Medical University
- Hebei Medical University - The Second Hospital
- Tianjin Medical University General Hospital
- Tongji Hospital Tongji Medical College Huazhong University of Science and Technology
- Wuxi People's Hospital
- The First Affiliated Hospital of Zhengzhou University
- Fakultni nemocnice Brno
- Fakultni Nemocnice; Interni Klinika - odd. Invazivni Kardiologie
- Thomayerova nemocnice; Lekarna - pavilon H
- Krajska nemocnice T. Bati a.s.; Neurologicke oddeleni
- Gentofte Hospital
- Odense Universitetshospital
- Hopital Avicenne
- Centre Hospitalier Regional Universitaire de Brest - Hopital de la Cavale Blanche
- Hopital Louis Pradel
- CHU Hopitaux de Bordeaux
- CHU Dijon Bourgogne Hôpital François Mitterand
- CHU de Grenoble - Hôpital André Michallon; Pole Pharmacie
- Centre Hospitalier Regional Universitaire de Lille
- Servie de Pneumologie et centre de Transplantation Pulmonaire
- CHU Nice - Hôpital Pasteur 2
- Hopital Bichat Claude Bernard; Hepatologie Gastro Enterologie
- Centre Hospitalier Universitaire de Reims; l'Hopital Maison Blanche
- Centre Hospitalier Universitaire de Rennes
- CHU Tours - Hôpital Bretonneau
- Evang. Lungenklinik Berlin Klinik für Pneumologie
- Thoraxklinik-Heidelberg gGmbH; Apotheke der Thoraxklinik
- Lungenfachklinik Immenhausen
- Praxis für Pneumologie Dr. Silke Mronga & Dr. Lukas Jerrentrup
- Lungenklinik Münnerstadt, Thoraxzentrum Bezirk Unterfranken
- Krankenhaus Bethanien gGmbH
- Evangelismos Hospital; Endocrinology, Diabetes & Metabolism
- Attikon University General Hospital
- University General Hospital of Heraklion
- University Hospital of Ioannina; Pulmonology Department
- Athens Medical Center
- University of Thessaly Faculty of Medicine
- University General Hospital of Patras
- "General hospital of Chest Diseases ""Sotiria"", 7th Pulmonary Clinic "
- General Hospital of Thessaloniki G. Papanikolaou
- Prince of Wales Hospital; Dept. of Medicine & Therapeutics
- The University of Hong Kong; Queen Mary Hospital
- Semmelweis University
- Debreceni Egyetem
- Markusovszky Egyetemi Oktatokorhaz ; SZEMESZET
- Szent Borbala Korhaz
- Tudogyogyintezet Torokbalint; Onkologiai és Jarobeteg Centrum
- Barzilai Medical Center; Neurology Department
- Shamir medical center
- Ben-Gurion University of the Negev - Soroka University Medical Center - Pulmonology Institute
- Rambam Health Care Campus
- Edith Wolfson Medical Center
- Shaare Zedek Medical Center
- Hadassah Medical Center
- Meir Medical Center
- Rabin Medical Center
- The Chaim Sheba Medical Center
- Kaplan Medical Center
- Tel Aviv Sourasky Medical Center; Department of Neurology
- Azienda Ospedaliera Papa Giovanni XXIII
- "AZIENDA OSPEDALIERA DEI COLLI Monaldi-Cotugno-CTO - Pneumologia "
- Azienda Ospedaliera Universitaria Federico II
- Ospedale Morgagni Pierantoni; Patologia clinica
- A.O.U. Policlinico di Modena
- Policlinico Tor Vergata - U.O.C. Malattie Apparato Respiratorio
- Fondazione Policlinico Universitario A Gemelli; Servizio di Farmacia
- Ospedale San Giuseppe; U.O. di Pneumologia
- Asst Santi Paolo E Carlo
- Ospedale San Gerardo
- Fondazione IRCCS Policlinico San Matteo Divisione di EmatologiaDipartimento di Onco-Ematologia
- Policlinico Riuniti di Foggia - Department of Medical and Surgical Sciences - University of Foggia
- A.O.U. Sassari; Dip. Medicina Clinica e Sperimentale
- Azienda Ospedaliero - Universitaria Policlinico - Vittorio Emanuele
- Az. Osp. Univ. P. Giaccone; UOC di Pneumologia
- Ismett Istituto Mediterraneo Trapianti E Terapie Alta Specializzazione;Pneumologia
- AOUC Azienda Ospedaliero-Universitaria Careggi; Neurologia 2
- A.O. Univ. Senese Policlinico S. Maria alle Scotte; Dip. Medicina clinica e Scienze Immunologiche
- Azienda Ospedale Universita Di Padova; Divisione Clinicizzata Di Nefrologia 1
- University of Padova Ca' Foncello Hospital Immunologic & Respiratory Rare Diseases Center
- Nagoya University Hospital
- Chiba University Hospital
- National Hospital Organization Kyushu Medical Center
- Fukuoka University Hospital
- Kobe City Medical Center General Hospital
- National Hospital Organization Himeji Medical Center
- Kameda Medical Center
- Kanagawa Cardiovascular and Respiratory Center
- Nippon Medical School Musashi Kosugi Hospital
- Saiseikai Kumamoto Hospital
- Nagasaki University Hospital
- National Hospital Organization Ibarakihigashi National Hospital; Center for Clinical Research
- Kurashiki Central Hospital
- National Hospital Organization Kinki-Chuo Chest Medical Center
- Tosei General Hospital
- Tenri Hospital
- Jichi Medical University Hospital
- Tokushima University Hospital
- Tokyo Medical Ando Dentaluni Hospital Faculty of Medicine; Surgical Oncology
- Center Hospital of the National Center for Global Health and Medicine
- The Catholic University of Korea Bucheon St. Mary's Hospital
- Gacheon University Gil Medical Center
- Seoul National University Bundang Hospital
- The Catholic University of Korea Yeouido St. Mary's Hospital; Hematology-Oncology
- Seoul National University Hospital (SNUH) - Medical Oncology Center
- Soonchunhyang University Hospital
- Asan Medical Center
- Korea University Guro Hospital
- Samsung Medical Center
- Unidad Médica para la Salud Integral UMSI
- Unidad de Investigacion CIMA SC
- Centro Respiratorio de México
- INER- Instituto Nacional de Enfermedades Respiratorias"Ismae
- CICC Morelia
- Sint Antonius Ziekenhuis, locatie Nieuwegein
- Erasmus Medisch Centrum
- Auckland City Hospital
- NZ Respiratory & Sleep Institute
- University of Otago, Christchurch
- Waikato Hospital; Gastro Research
- Tauranga Hospital
- Helse Bergen HF Haukeland universitetssykehus; Hudavdelingen
- Akershus universitetssykehus
- Oslo University Hospital HF, Rikshospitalet
- Centrum Medycyny Oddechowej Mroz sp. j.
- Nasz Lekarz Osrodek Badan Klinicznych
- SPZOZ Uniwersytecki Szpital Kliniczny nr 1 im. Norberta Barlickiego Uniwersytetu Medycznego w Lodzi
- Hospital de Braga; Centro Clínico Académico (Piso 1, Ala E)
- Centro Hospitalar do Alto Ave; EPE
- Centro Hospitalar Universitario Lisboa Norte - Hospital Pulido Valente
- CHVNG/E_Unidade 1; Servico de Pneumologia
- National University Hospital
- Singapore General Hospital
- Tan Tock Seng Hospital; Oncology
- University of Cape Town Lung Institute; Lung Clinical Research
- Vergelegen Medi-Clinic
- HUA - Txagorritxu
- Hospital Univ. Central de Asturias
- Hospital Universitario de Bellvitge
- Corporació Sanitaria Parc Taulí; Servicio de Neurología
- Hospital Universitario Marques de Valdecilla
- CHUS ? H. Clinico U. de Santiago
- Hospital Universitario del Henares
- Hospital Galdakao-Usansolo
- Hospital de la Santa Creu i Sant Pau; Servicio de Neumologia
- Hospital Clinic I Provincial
- Hospital Germans Trias i Pujol
- Hospital Virgen de las Nieves; Servicio de Neumologia
- Hospital Universitario de la Princesa; Servicio de Aparato Digestivo
- Clinica Universidad de Navarra ; Servicio de Farmacia
- Universidad Autonoma de Madrid (UAM) - Hospital Universitario La Paz
- Hospital Ramón y Cajal;Servicio de Neumología
- Fundacion Jimenez Diaz-UTE
- Hosp. Clinico San Carlos
- Hospital Universitario 12 de Octubre
- Hospital Clinico Universitario Virgen de la Victoria
- Hospital Clinico Universitario de Salamanca
- Hospital Clinico Universitario de Valencia
- Buddhist Tzu Chi Dalin General Hospital; Rheumatology
- Kaohsiung Medical University Hospital; Chung-Ho Memorial Hospital
- China Medical University Hospital
- National Cheng Kung University Hospital
- National Taiwan University Hospital
- Far Eastern Memorial Hospital; Department of Clinical Pathology
- Veterans General Hospital - Taichung
- Istanbul Universitesi Onkoloji Enstitüsü Hastanesi
- Cukurova Universitesi Tip Fakultesi Balcali Hastanesi; Balcali
- Ankara Universitesi Tip Fakultesi Hastaneleri - Cebeci Hastanesi
- Uludag Universitesi - Saglik Uygulama ve Arastirrma Merkezi
- Gaziantep Universitesi Tip Fakultesi
- Yedikule Gogus Hastaliklari ve Gogus Cerrahisi Egitim ve Arastirma Hastanesi
- Ege Universitesi Tip Fakultesi Hastanesi
- Dokuz Eylul University Faculty of Medicine; Chest Diseases
- Kocaeli Universitesi Tip Fakultesi
- Marmara Universitesi Hastanesi Marmara University Hospital
- Eriyes universitesi T?p Fakultesi Hastanesi
- Mersin Universitesi Tip Fakultesi Hastanesi; Tibbi Onkoloji Birimi
- Akdeniz University Faculty of Medicine Department of Pulmonology
- Koc Universitesi (KU) Tip Fakultesi (Koc University School of Medicine)
Arms of the Study
Arm 1
Arm Type
Experimental
Arm Label
PRM-151
Arm Description
Corhort A: Participants entering, following participation in study PRM-151-202. Cohort B: Participants entering, following participation in study WA42293.
Outcomes
Primary Outcome Measures
Percentage of Participants with Adverse Events (AE)
Severity will be determined according to the 5-point severity scale (National Cancer Institute Common Terminology Criteria for Adverse Events, Version 5.0 [NCI CTCAE, v.5.0]).
Percentage of Participants with Infusion Related Reactions (IRRs) and other AEs of Special Interest
Percentage of of Participants Permanently Discontinuing Study Treatment due to AEs
Change from Baseline in Targeted Clinical Laboratory Test Results
Secondary Outcome Measures
Annual Rate of Change in Forced Vital Capacity (FVC) (mL)
Annual Rate of Change in 6-Minute Walk Distance (6MWD)
Annual Rate of Change in FVC% Predicted
Annual Rate of Change in Carbon Monoxide Diffusing Capacity (DLCO)
Time to Disease Progression
Time to first occurrence of >=10% absolute decline in % predicted FVC, >=15% relative decline in 6MWD, or death
Survival
IPF-related Mortality
Respiratory-related Mortality
Plasma Concentrations of PRM-151 at Specified Timepoints
Prevalence of Anti-drug Antibodies (ADAs) to PRM-151 at Baseline
Percentage of Participants with ADAs During the Study
Full Information
1. Study Identification
Unique Protocol Identification Number
NCT04594707
Brief Title
A Study to Evaluate Long Term Safety and Efficacy of Recombinant Human Pentraxin-2 (rhPTX-2; PRM-151) in Participants With Idiopathic Pulmonary Fibrosis
Acronym
STARSCAPE-OLE
Official Title
A Phase III Open-label Extension Study to Evaluate Long-term Safety and Efficacy of PRM-151 in Patients With Idiopathic Pulmonary Fibrosis (IPF)
Study Type
Interventional
2. Study Status
Record Verification Date
March 2023
Overall Recruitment Status
Terminated
Why Stopped
The study was terminated by Sponsor as the futility analysis outcome indicated that the study was unlikely to meet the predefined primary objective of the study. No new safety concerns were identified.
Study Start Date
August 30, 2021 (Actual)
Primary Completion Date
February 10, 2023 (Actual)
Study Completion Date
February 10, 2023 (Actual)
3. Sponsor/Collaborators
Responsible Party, by Official Title
Sponsor
Name of the Sponsor
Hoffmann-La Roche
4. Oversight
Studies a U.S. FDA-regulated Drug Product
Yes
Studies a U.S. FDA-regulated Device Product
No
Data Monitoring Committee
Yes
5. Study Description
Brief Summary
This study will evaulate the long-term safety, efficacy and pharmacokinetics (PK) of recombinant human pentraxin-2 (rhPTX-2; PRM-151) zinpentraxin alfa, administered by intravenous (IV) infusion to participants with idiopathic pulmonary fibrosis (IPF).
Detailed Description
This study is being conducted for the treatment of eligible participants who have taken part in Study PRM-151-202 and received the open-label study drug or completed the Phase III Study WA42293 with PRM-151. Participants who have discontinued treatment from or have completed Study WA42293 and do not want to receive PRM-151 in this study, will be invited to enroll in survival follow-up.
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Idiopathic Pulmonary Fibrosis
7. Study Design
Primary Purpose
Treatment
Study Phase
Phase 3
Interventional Study Model
Single Group Assignment
Masking
None (Open Label)
Allocation
N/A
Enrollment
117 (Actual)
8. Arms, Groups, and Interventions
Arm Title
PRM-151
Arm Type
Experimental
Arm Description
Corhort A: Participants entering, following participation in study PRM-151-202.
Cohort B: Participants entering, following participation in study WA42293.
Intervention Type
Drug
Intervention Name(s)
PRM-151 (Zinpentraxin Alfa)
Other Intervention Name(s)
Zinpentraxin Alfa
Intervention Description
Cohort A: Participants will receive three loading doses of open-label PRM-151 on days 1, 3, and 5, then one infusion every 4 weeks (Q4W). 10 mg/kg of PRM 151 will be administered by intravenous (IV) infusion over 60 minutes on days 1, 3, and 5, then one infusion every 4 weeks.
Cohort B: Participants previously randomized to the placebo in WA42293 will receive study medication in the three loading doses on days 1, 3 and 5 in a blinded fashion. All three doses will contain PRM-151. Participants previously randomized to the treatment arm in WA42293 will receive study medication in the three loading doses on days 1, 3 and 5 in a blinded fashion. One of the three doses will contain PRM-151, whereas two doses will contain placebo.
Primary Outcome Measure Information:
Title
Percentage of Participants with Adverse Events (AE)
Description
Severity will be determined according to the 5-point severity scale (National Cancer Institute Common Terminology Criteria for Adverse Events, Version 5.0 [NCI CTCAE, v.5.0]).
Time Frame
From baseline until 8 weeks after the final dose
Title
Percentage of Participants with Infusion Related Reactions (IRRs) and other AEs of Special Interest
Time Frame
From baseline until 8 weeks after the final dose
Title
Percentage of of Participants Permanently Discontinuing Study Treatment due to AEs
Time Frame
From baseline until 8 weeks after the final dose
Title
Change from Baseline in Targeted Clinical Laboratory Test Results
Time Frame
From baseline until 8 weeks after the final dose
Secondary Outcome Measure Information:
Title
Annual Rate of Change in Forced Vital Capacity (FVC) (mL)
Time Frame
From baseline until study completion (up tp 4 years)
Title
Annual Rate of Change in 6-Minute Walk Distance (6MWD)
Time Frame
From baseline until study completion (up tp 4 years)
Title
Annual Rate of Change in FVC% Predicted
Time Frame
From baseline until study completion (up tp 4 years)
Title
Annual Rate of Change in Carbon Monoxide Diffusing Capacity (DLCO)
Time Frame
From baseline until study completion (up tp 4 years)
Title
Time to Disease Progression
Description
Time to first occurrence of >=10% absolute decline in % predicted FVC, >=15% relative decline in 6MWD, or death
Time Frame
From the time of randomization until disease progression or death (up tp 4 years)
Title
Survival
Time Frame
Every 6 Months and at study completion (up to 4 years)
Title
IPF-related Mortality
Time Frame
Every 6 Months and at study completion (up to 4 years)
Title
Respiratory-related Mortality
Time Frame
Every 6 Months and at study completion (up to 4 years)
Title
Plasma Concentrations of PRM-151 at Specified Timepoints
Time Frame
Days 1, 3 and 5, Weeks 4, 12 and 24
Title
Prevalence of Anti-drug Antibodies (ADAs) to PRM-151 at Baseline
Time Frame
Baseline (Day 1)
Title
Percentage of Participants with ADAs During the Study
Time Frame
Weeks 4, 12 and 24
10. Eligibility
Sex
All
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria:
Taken part in either of the prior PRM-151 studies: PRM-151-202 or WA42293.
For women of childbearing potential: agreement to remain abstinent (refrain from heterosexual intercourse) or use contraception.
For men: agreement to remain abstinent (refrain from heterosexual intercourse) or use a condom, and agreement to refrain from donating sperm.
Exclusion Criteria:
Acute respiratory or systemic bacterial, viral, or fungal infection at the first visit of the OLE, or within 2 weeks of the first visit for patients joining Cohort A (from Study PRM-151-202).
History of smoking within 3 months prior to the first visit in the OLE.
History of alcohol or substance use disorder within 2 years prior to the first visit of the OLE or known or suspected active alcohol or substance-use disorder.
History of severe allergic reaction or anaphylactic reaction to PRM-151.
Clinically significant abnormality on ECG during eligibility assessment that, in the opinion of the investigator, may pose an additional risk in administering study drug to the participant.
Prolonged corrected QT interval > 450 ms (for men) or > 470 ms (for women) based on the Fridericia correction formula.
Clinically significant laboratory test abnormalities (hematology, serumchemistry, and urinalysis) that, in the opinion of the investigator, may pose an additional risk in administering study drug to the participant.
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Clinical Trials
Organizational Affiliation
Hoffmann-La Roche
Official's Role
Study Director
Facility Information:
Facility Name
University of Alabama at Birmingham
City
Birmingham
State/Province
Alabama
ZIP/Postal Code
35294
Country
United States
Facility Name
University of California Davis
City
Sacramento
State/Province
California
ZIP/Postal Code
95817
Country
United States
Facility Name
Inst. of Healthcare Assessment, Inc.
City
San Diego
State/Province
California
ZIP/Postal Code
92120
Country
United States
Facility Name
UCSF Medical Center
City
San Francisco
State/Province
California
ZIP/Postal Code
94143-0748
Country
United States
Facility Name
National Jewish Health Medical Center
City
Denver
State/Province
Colorado
ZIP/Postal Code
80045-2541
Country
United States
Facility Name
Yale New Haven Hospital
City
New Haven
State/Province
Connecticut
ZIP/Postal Code
06510
Country
United States
Facility Name
Georgetown University Medical Center
City
Washington
State/Province
District of Columbia
ZIP/Postal Code
20007
Country
United States
Facility Name
Meris Clinical Research
City
Brandon
State/Province
Florida
ZIP/Postal Code
33511-5719
Country
United States
Facility Name
Florida Lung, Asthma and Sleep Specialists (FLASS) - Celebration
City
Celebration
State/Province
Florida
ZIP/Postal Code
34747-1818
Country
United States
Facility Name
Advanced Pulmonary & Sleep Research Institute of Florida
City
Daytona Beach
State/Province
Florida
ZIP/Postal Code
32117
Country
United States
Facility Name
University of Florida Health Pulmonology - Jacksonville
City
Jacksonville
State/Province
Florida
ZIP/Postal Code
32209
Country
United States
Facility Name
Advanced Pulmonary Research Institute
City
Loxahatchee Groves
State/Province
Florida
ZIP/Postal Code
33470-9216
Country
United States
Facility Name
Sarasota County Public Hospital
City
Sarasota
State/Province
Florida
ZIP/Postal Code
34239
Country
United States
Facility Name
Renstar Medical Research
City
Wesley Chapel
State/Province
Florida
ZIP/Postal Code
33544
Country
United States
Facility Name
Florida Pulmonary Research Institute, LLC
City
Winter Park
State/Province
Florida
ZIP/Postal Code
32789
Country
United States
Facility Name
NorthShore University HealthSystem
City
Evanston
State/Province
Illinois
ZIP/Postal Code
60201
Country
United States
Facility Name
University of Iowa Hospitals and Clinics; Investigational Drug Services
City
Iowa City
State/Province
Iowa
ZIP/Postal Code
52242
Country
United States
Facility Name
University of Kansas Medical Center
City
Kansas City
State/Province
Kansas
ZIP/Postal Code
66160
Country
United States
Facility Name
University of Louisville Health Sciences Center
City
Louisville
State/Province
Kentucky
ZIP/Postal Code
40202
Country
United States
Facility Name
Massachusetts General Hospital
City
Boston
State/Province
Massachusetts
ZIP/Postal Code
02114
Country
United States
Facility Name
University of Minnesota Medical Center
City
Minneapolis
State/Province
Minnesota
ZIP/Postal Code
29425-8911
Country
United States
Facility Name
Mayo Clinic Rochester
City
Rochester
State/Province
Minnesota
ZIP/Postal Code
55902
Country
United States
Facility Name
The Lung Research Center
City
Chesterfield
State/Province
Missouri
ZIP/Postal Code
63017-3625
Country
United States
Facility Name
Washington University
City
Saint Louis
State/Province
Missouri
ZIP/Postal Code
63128
Country
United States
Facility Name
University of Nebraska Medical Center
City
Omaha
State/Province
Nebraska
ZIP/Postal Code
68198-0600
Country
United States
Facility Name
Lenox Hill Hospital
City
New York
State/Province
New York
ZIP/Postal Code
10075
Country
United States
Facility Name
Pulmonix Research
City
Greensboro
State/Province
North Carolina
ZIP/Postal Code
27403-1127
Country
United States
Facility Name
PMG Research of Wilmington
City
Wilmington
State/Province
North Carolina
ZIP/Postal Code
28401
Country
United States
Facility Name
Oregon Health and Science University
City
Portland
State/Province
Oregon
ZIP/Postal Code
97239
Country
United States
Facility Name
Jefferson University Physicians (JUP) - Jefferson Pulmonary
City
Philadelphia
State/Province
Pennsylvania
ZIP/Postal Code
19107
Country
United States
Facility Name
University of Pittsburgh Medical Center
City
Pittsburgh
State/Province
Pennsylvania
ZIP/Postal Code
15213
Country
United States
Facility Name
SleepMed of South Carolina
City
Columbia
State/Province
South Carolina
ZIP/Postal Code
29201-2953
Country
United States
Facility Name
Lowcountry Lung and Critical Care
City
North Charleston
State/Province
South Carolina
ZIP/Postal Code
29406
Country
United States
Facility Name
Spartanburg Medical Center
City
Spartanburg
State/Province
South Carolina
ZIP/Postal Code
29303
Country
United States
Facility Name
Vanderbilt University Medical Center
City
Nashville
State/Province
Tennessee
ZIP/Postal Code
37212
Country
United States
Facility Name
University of Texas Medical Branch at Galveston
City
Galveston
State/Province
Texas
ZIP/Postal Code
77555
Country
United States
Facility Name
Metroplex Pulmonology & Sleep Center
City
McKinney
State/Province
Texas
ZIP/Postal Code
75069
Country
United States
Facility Name
University Of Utah Hosp & Clin; Investigational Pharmacy
City
Salt Lake City
State/Province
Utah
ZIP/Postal Code
84132
Country
United States
Facility Name
Inova Fairfax Hospital
City
Falls Church
State/Province
Virginia
ZIP/Postal Code
22031
Country
United States
Facility Name
Virginia Commonwealth University
City
Richmond
State/Province
Virginia
ZIP/Postal Code
23219-1901
Country
United States
Facility Name
Hospital Britanico de Buenos Aires
City
Ciudad Autonoma Buenos Aires
ZIP/Postal Code
C1284AEB
Country
Argentina
Facility Name
Fundacion Respirar (Centro Medico Dra. De Salvo)
City
Ciudad Autonoma Buenos Aires
ZIP/Postal Code
C1426ABP
Country
Argentina
Facility Name
Instituto de Medicina Respiratoria, IMeR; Clinic/Outpatient Facility
City
Córdoba
ZIP/Postal Code
X5003DCE
Country
Argentina
Facility Name
Hospital Universitario Austral
City
Derqui-Pilar
ZIP/Postal Code
B1629ODT
Country
Argentina
Facility Name
Centro Medico de Enfermedades Respiratorias (CEMER)
City
Florida, Buenos Aires
ZIP/Postal Code
B1602DQD
Country
Argentina
Facility Name
Centro de estudios respiratorios
City
Mar Del Plata
ZIP/Postal Code
B7600CLK
Country
Argentina
Facility Name
INSARES
City
Mendoza, Mendoza City
ZIP/Postal Code
M5500CCG
Country
Argentina
Facility Name
Fundacion Scherbovsky
City
Mendoza
ZIP/Postal Code
M5500AYB
Country
Argentina
Facility Name
Instituto Medico de la Fundacion Estudios Clinicos
City
Rosario
ZIP/Postal Code
S2000DEJ
Country
Argentina
Facility Name
Investigaciones en Patologias Respiratorias
City
San Miguel de Tucuman
ZIP/Postal Code
T4000IAR
Country
Argentina
Facility Name
Royal Prince Alfred Hospital
City
Camperdown
State/Province
New South Wales
ZIP/Postal Code
2050
Country
Australia
Facility Name
Cairns Base Hospital; Cancer Care Centre
City
Cairns
State/Province
Queensland
ZIP/Postal Code
4870
Country
Australia
Facility Name
Lung Research Queensland
City
Nundah
State/Province
Queensland
ZIP/Postal Code
4101
Country
Australia
Facility Name
Princess Alexandra Hospital
City
Woolloongabba
State/Province
Queensland
ZIP/Postal Code
4102
Country
Australia
Facility Name
Monash Medical Centre; Medicine
City
Melbourne
State/Province
Victoria
ZIP/Postal Code
3186
Country
Australia
Facility Name
The Alfred Hospital
City
Prahan
State/Province
Victoria
ZIP/Postal Code
3181
Country
Australia
Facility Name
ULB Hôpital Erasme
City
Brussels
ZIP/Postal Code
1070
Country
Belgium
Facility Name
Cliniques Universitaires Saint-Luc; Pharmacy
City
Bruxelles
ZIP/Postal Code
1200
Country
Belgium
Facility Name
UZ Leuven
City
Leuven
ZIP/Postal Code
3000
Country
Belgium
Facility Name
C. H. U. Sart-Tilman; Laboratory
City
Liège
ZIP/Postal Code
4000
Country
Belgium
Facility Name
CHU UCL Namur / site Godinne
City
Yvoir
ZIP/Postal Code
B5530
Country
Belgium
Facility Name
Synergy Respiratory Care
City
Sherwood Park
State/Province
Alberta
ZIP/Postal Code
T8H ON2
Country
Canada
Facility Name
Kelowna Respiratory and Allergy Clinic
City
Kelowna
State/Province
British Columbia
ZIP/Postal Code
V1W 1V3
Country
Canada
Facility Name
The Rhema Research Institute
City
Owen Sound
State/Province
Ontario
ZIP/Postal Code
N4K 6M9
Country
Canada
Facility Name
Dr. Syed Anees Medicine Profession Corporation
City
Windsor
State/Province
Ontario
ZIP/Postal Code
N8X 1T3
Country
Canada
Facility Name
C.I.C. Mauricie
City
Trois-Rivières
State/Province
Quebec
ZIP/Postal Code
G8T 7A1
Country
Canada
Facility Name
Peking Union Medical College Hospital; Pharmacy
City
Beijing City
ZIP/Postal Code
100730
Country
China
Facility Name
Beijing Friendship Hospital Affiliated of Capital University of Medical Science
City
Beijing Shi
ZIP/Postal Code
100050
Country
China
Facility Name
The Second Xiangya Hospital of Central South University
City
Changsha
ZIP/Postal Code
410011
Country
China
Facility Name
The Third Xiangya Hospital Of Central South University
City
Changsha
ZIP/Postal Code
410013
Country
China
Facility Name
Shengjing Hospital of China Medical University
City
ShenYang
ZIP/Postal Code
110004
Country
China
Facility Name
Hebei Medical University - The Second Hospital
City
Shijiazhuang City
ZIP/Postal Code
050004
Country
China
Facility Name
Tianjin Medical University General Hospital
City
Tianjin
ZIP/Postal Code
300052
Country
China
Facility Name
Tongji Hospital Tongji Medical College Huazhong University of Science and Technology
City
Wuhan City
ZIP/Postal Code
430030
Country
China
Facility Name
Wuxi People's Hospital
City
Wuxi
ZIP/Postal Code
214023
Country
China
Facility Name
The First Affiliated Hospital of Zhengzhou University
City
Zhengzhou
ZIP/Postal Code
450052
Country
China
Facility Name
Fakultni nemocnice Brno
City
Brno
ZIP/Postal Code
613 00
Country
Czechia
Facility Name
Fakultni Nemocnice; Interni Klinika - odd. Invazivni Kardiologie
City
Hradec Kralove
ZIP/Postal Code
500 05
Country
Czechia
Facility Name
Thomayerova nemocnice; Lekarna - pavilon H
City
Praha 4
ZIP/Postal Code
140 00
Country
Czechia
Facility Name
Krajska nemocnice T. Bati a.s.; Neurologicke oddeleni
City
Zlin
ZIP/Postal Code
760 01
Country
Czechia
Facility Name
Gentofte Hospital
City
Hellerup
ZIP/Postal Code
2900
Country
Denmark
Facility Name
Odense Universitetshospital
City
Odense C
ZIP/Postal Code
5000
Country
Denmark
Facility Name
Hopital Avicenne
City
Bobigny
ZIP/Postal Code
93000
Country
France
Facility Name
Centre Hospitalier Regional Universitaire de Brest - Hopital de la Cavale Blanche
City
Brest
ZIP/Postal Code
29200
Country
France
Facility Name
Hopital Louis Pradel
City
Bron
ZIP/Postal Code
69677
Country
France
Facility Name
CHU Hopitaux de Bordeaux
City
CHU Hopitaux De Bordeaux
ZIP/Postal Code
33000
Country
France
Facility Name
CHU Dijon Bourgogne Hôpital François Mitterand
City
Dijon
ZIP/Postal Code
21000
Country
France
Facility Name
CHU de Grenoble - Hôpital André Michallon; Pole Pharmacie
City
La Tronche
ZIP/Postal Code
38700
Country
France
Facility Name
Centre Hospitalier Regional Universitaire de Lille
City
Lille
Country
France
Facility Name
Servie de Pneumologie et centre de Transplantation Pulmonaire
City
Marseille
ZIP/Postal Code
13354
Country
France
Facility Name
CHU Nice - Hôpital Pasteur 2
City
Nice
ZIP/Postal Code
06000
Country
France
Facility Name
Hopital Bichat Claude Bernard; Hepatologie Gastro Enterologie
City
Paris
ZIP/Postal Code
75018
Country
France
Facility Name
Centre Hospitalier Universitaire de Reims; l'Hopital Maison Blanche
City
Reims
ZIP/Postal Code
51092
Country
France
Facility Name
Centre Hospitalier Universitaire de Rennes
City
Rennes
ZIP/Postal Code
35033
Country
France
Facility Name
CHU Tours - Hôpital Bretonneau
City
Tours
ZIP/Postal Code
37044
Country
France
Facility Name
Evang. Lungenklinik Berlin Klinik für Pneumologie
City
Berlin
ZIP/Postal Code
13125
Country
Germany
Facility Name
Thoraxklinik-Heidelberg gGmbH; Apotheke der Thoraxklinik
City
Heidelberg
ZIP/Postal Code
69120
Country
Germany
Facility Name
Lungenfachklinik Immenhausen
City
Immenhausen
ZIP/Postal Code
34376
Country
Germany
Facility Name
Praxis für Pneumologie Dr. Silke Mronga & Dr. Lukas Jerrentrup
City
Marburg
ZIP/Postal Code
35037
Country
Germany
Facility Name
Lungenklinik Münnerstadt, Thoraxzentrum Bezirk Unterfranken
City
Münnerstadt
ZIP/Postal Code
97702
Country
Germany
Facility Name
Krankenhaus Bethanien gGmbH
City
Solingen
ZIP/Postal Code
42699
Country
Germany
Facility Name
Evangelismos Hospital; Endocrinology, Diabetes & Metabolism
City
Athens
ZIP/Postal Code
10676
Country
Greece
Facility Name
Attikon University General Hospital
City
Chaidari
ZIP/Postal Code
124 62
Country
Greece
Facility Name
University General Hospital of Heraklion
City
Herakleion
ZIP/Postal Code
711 10
Country
Greece
Facility Name
University Hospital of Ioannina; Pulmonology Department
City
Ioannina
ZIP/Postal Code
455 00
Country
Greece
Facility Name
Athens Medical Center
City
Marousi
ZIP/Postal Code
151 25
Country
Greece
Facility Name
University of Thessaly Faculty of Medicine
City
Mezourlo
ZIP/Postal Code
41110
Country
Greece
Facility Name
University General Hospital of Patras
City
Patras
ZIP/Postal Code
265 00
Country
Greece
Facility Name
"General hospital of Chest Diseases ""Sotiria"", 7th Pulmonary Clinic "
City
Sotiria Athens
ZIP/Postal Code
115 27
Country
Greece
Facility Name
General Hospital of Thessaloniki G. Papanikolaou
City
Thessaloniki
ZIP/Postal Code
57010
Country
Greece
Facility Name
Prince of Wales Hospital; Dept. of Medicine & Therapeutics
City
Hong Kong
Country
Hong Kong
Facility Name
The University of Hong Kong; Queen Mary Hospital
City
Hong Kong
Country
Hong Kong
Facility Name
Semmelweis University
City
Budapest
ZIP/Postal Code
1081
Country
Hungary
Facility Name
Debreceni Egyetem
City
Debrecen
ZIP/Postal Code
4032
Country
Hungary
Facility Name
Markusovszky Egyetemi Oktatokorhaz ; SZEMESZET
City
Szombathely
ZIP/Postal Code
9700
Country
Hungary
Facility Name
Szent Borbala Korhaz
City
Tatabánya
ZIP/Postal Code
2800
Country
Hungary
Facility Name
Tudogyogyintezet Torokbalint; Onkologiai és Jarobeteg Centrum
City
Törökbálint
ZIP/Postal Code
2045
Country
Hungary
Facility Name
Barzilai Medical Center; Neurology Department
City
Ashkelon
ZIP/Postal Code
7830604
Country
Israel
Facility Name
Shamir medical center
City
Be'er Ya'akov
ZIP/Postal Code
0070300
Country
Israel
Facility Name
Ben-Gurion University of the Negev - Soroka University Medical Center - Pulmonology Institute
City
Beer sheva
ZIP/Postal Code
8410101
Country
Israel
Facility Name
Rambam Health Care Campus
City
Haifa
ZIP/Postal Code
3109600
Country
Israel
Facility Name
Edith Wolfson Medical Center
City
Holon
ZIP/Postal Code
5822012
Country
Israel
Facility Name
Shaare Zedek Medical Center
City
Jerusalem
ZIP/Postal Code
9103102
Country
Israel
Facility Name
Hadassah Medical Center
City
Jerusalem
ZIP/Postal Code
9112000
Country
Israel
Facility Name
Meir Medical Center
City
Kfar- Saba
ZIP/Postal Code
4428164
Country
Israel
Facility Name
Rabin Medical Center
City
Petach Tiqwa
ZIP/Postal Code
4941492
Country
Israel
Facility Name
The Chaim Sheba Medical Center
City
Ramat Gan
ZIP/Postal Code
5211401
Country
Israel
Facility Name
Kaplan Medical Center
City
Rehovot
ZIP/Postal Code
7610001
Country
Israel
Facility Name
Tel Aviv Sourasky Medical Center; Department of Neurology
City
Tel Aviv
ZIP/Postal Code
6423906
Country
Israel
Facility Name
Azienda Ospedaliera Papa Giovanni XXIII
City
Bergamo
State/Province
Abruzzo
ZIP/Postal Code
24060
Country
Italy
Facility Name
"AZIENDA OSPEDALIERA DEI COLLI Monaldi-Cotugno-CTO - Pneumologia "
City
Napoli
State/Province
Campania
ZIP/Postal Code
80131
Country
Italy
Facility Name
Azienda Ospedaliera Universitaria Federico II
City
Napoli
State/Province
Campania
ZIP/Postal Code
80131
Country
Italy
Facility Name
Ospedale Morgagni Pierantoni; Patologia clinica
City
Forlì
State/Province
Emilia-Romagna
ZIP/Postal Code
47100
Country
Italy
Facility Name
A.O.U. Policlinico di Modena
City
Modena
State/Province
Emilia-Romagna
ZIP/Postal Code
40124
Country
Italy
Facility Name
Policlinico Tor Vergata - U.O.C. Malattie Apparato Respiratorio
City
Rome
State/Province
Lazio
ZIP/Postal Code
00133
Country
Italy
Facility Name
Fondazione Policlinico Universitario A Gemelli; Servizio di Farmacia
City
Rome
State/Province
Lazio
ZIP/Postal Code
00168
Country
Italy
Facility Name
Ospedale San Giuseppe; U.O. di Pneumologia
City
Milano
State/Province
Lombardia
ZIP/Postal Code
20123
Country
Italy
Facility Name
Asst Santi Paolo E Carlo
City
Milano
State/Province
Lombardia
ZIP/Postal Code
20142
Country
Italy
Facility Name
Ospedale San Gerardo
City
Monza
State/Province
Lombardia
ZIP/Postal Code
20900
Country
Italy
Facility Name
Fondazione IRCCS Policlinico San Matteo Divisione di EmatologiaDipartimento di Onco-Ematologia
City
Pavia
State/Province
Lombardia
ZIP/Postal Code
27100
Country
Italy
Facility Name
Policlinico Riuniti di Foggia - Department of Medical and Surgical Sciences - University of Foggia
City
Foggia
State/Province
Puglia
ZIP/Postal Code
71122
Country
Italy
Facility Name
A.O.U. Sassari; Dip. Medicina Clinica e Sperimentale
City
Sassari
State/Province
Sardegna
ZIP/Postal Code
07100
Country
Italy
Facility Name
Azienda Ospedaliero - Universitaria Policlinico - Vittorio Emanuele
City
Catania
State/Province
Sicilia
ZIP/Postal Code
95123
Country
Italy
Facility Name
Az. Osp. Univ. P. Giaccone; UOC di Pneumologia
City
Palermo
State/Province
Sicilia
ZIP/Postal Code
90127
Country
Italy
Facility Name
Ismett Istituto Mediterraneo Trapianti E Terapie Alta Specializzazione;Pneumologia
City
Palermo
State/Province
Sicilia
ZIP/Postal Code
90127
Country
Italy
Facility Name
AOUC Azienda Ospedaliero-Universitaria Careggi; Neurologia 2
City
Firenze
State/Province
Toscana
ZIP/Postal Code
50134
Country
Italy
Facility Name
A.O. Univ. Senese Policlinico S. Maria alle Scotte; Dip. Medicina clinica e Scienze Immunologiche
City
Siena
State/Province
Toscana
ZIP/Postal Code
53100
Country
Italy
Facility Name
Azienda Ospedale Universita Di Padova; Divisione Clinicizzata Di Nefrologia 1
City
Padova
State/Province
Veneto
ZIP/Postal Code
35128
Country
Italy
Facility Name
University of Padova Ca' Foncello Hospital Immunologic & Respiratory Rare Diseases Center
City
Treviso
State/Province
Veneto
ZIP/Postal Code
31100
Country
Italy
Facility Name
Nagoya University Hospital
City
Aichi
ZIP/Postal Code
466-8560
Country
Japan
Facility Name
Chiba University Hospital
City
Chiba
ZIP/Postal Code
260-8677
Country
Japan
Facility Name
National Hospital Organization Kyushu Medical Center
City
Fukuoka
ZIP/Postal Code
810-8563
Country
Japan
Facility Name
Fukuoka University Hospital
City
Fukuoka
ZIP/Postal Code
814-0180
Country
Japan
Facility Name
Kobe City Medical Center General Hospital
City
Hyogo
ZIP/Postal Code
650-0047
Country
Japan
Facility Name
National Hospital Organization Himeji Medical Center
City
Hyogo
ZIP/Postal Code
670-8520
Country
Japan
Facility Name
Kameda Medical Center
City
Kamogawa
ZIP/Postal Code
296-0041
Country
Japan
Facility Name
Kanagawa Cardiovascular and Respiratory Center
City
Kanagawa
ZIP/Postal Code
236-0051
Country
Japan
Facility Name
Nippon Medical School Musashi Kosugi Hospital
City
Kawasaki-Shi
Country
Japan
Facility Name
Saiseikai Kumamoto Hospital
City
Kumamoto-Shi
ZIP/Postal Code
861-4101
Country
Japan
Facility Name
Nagasaki University Hospital
City
Nagasaki
ZIP/Postal Code
852-8501
Country
Japan
Facility Name
National Hospital Organization Ibarakihigashi National Hospital; Center for Clinical Research
City
Naka-gun
ZIP/Postal Code
319-1113
Country
Japan
Facility Name
Kurashiki Central Hospital
City
Okayama
ZIP/Postal Code
710-8602
Country
Japan
Facility Name
National Hospital Organization Kinki-Chuo Chest Medical Center
City
Sakai-shi
ZIP/Postal Code
591-8555
Country
Japan
Facility Name
Tosei General Hospital
City
Seto-shi
ZIP/Postal Code
489-8642
Country
Japan
Facility Name
Tenri Hospital
City
Tenri-Shi
ZIP/Postal Code
632-8552
Country
Japan
Facility Name
Jichi Medical University Hospital
City
Tochigi
ZIP/Postal Code
329-0498
Country
Japan
Facility Name
Tokushima University Hospital
City
Tokushima
ZIP/Postal Code
770-8503
Country
Japan
Facility Name
Tokyo Medical Ando Dentaluni Hospital Faculty of Medicine; Surgical Oncology
City
Tokyo
ZIP/Postal Code
113-0034
Country
Japan
Facility Name
Center Hospital of the National Center for Global Health and Medicine
City
Tokyo
ZIP/Postal Code
162-0052
Country
Japan
Facility Name
The Catholic University of Korea Bucheon St. Mary's Hospital
City
Gyeonggi-do
ZIP/Postal Code
14662
Country
Korea, Republic of
Facility Name
Gacheon University Gil Medical Center
City
Namdong-gu
ZIP/Postal Code
21565
Country
Korea, Republic of
Facility Name
Seoul National University Bundang Hospital
City
Seongnam-si
ZIP/Postal Code
13620
Country
Korea, Republic of
Facility Name
The Catholic University of Korea Yeouido St. Mary's Hospital; Hematology-Oncology
City
Seoul
ZIP/Postal Code
(0)7345
Country
Korea, Republic of
Facility Name
Seoul National University Hospital (SNUH) - Medical Oncology Center
City
Seoul
ZIP/Postal Code
03080
Country
Korea, Republic of
Facility Name
Soonchunhyang University Hospital
City
Seoul
ZIP/Postal Code
04401
Country
Korea, Republic of
Facility Name
Asan Medical Center
City
Seoul
ZIP/Postal Code
05505
Country
Korea, Republic of
Facility Name
Korea University Guro Hospital
City
Seoul
ZIP/Postal Code
08308
Country
Korea, Republic of
Facility Name
Samsung Medical Center
City
Seoul
ZIP/Postal Code
135-710
Country
Korea, Republic of
Facility Name
Unidad Médica para la Salud Integral UMSI
City
San Nicolás de Los Garza
State/Province
Nuevo LEON
ZIP/Postal Code
66465
Country
Mexico
Facility Name
Unidad de Investigacion CIMA SC
City
Chihuahua
ZIP/Postal Code
31200
Country
Mexico
Facility Name
Centro Respiratorio de México
City
Mexico
ZIP/Postal Code
14050
Country
Mexico
Facility Name
INER- Instituto Nacional de Enfermedades Respiratorias"Ismae
City
Mexico
ZIP/Postal Code
14080
Country
Mexico
Facility Name
CICC Morelia
City
Morelia
Country
Mexico
Facility Name
Sint Antonius Ziekenhuis, locatie Nieuwegein
City
Nieuwegein
ZIP/Postal Code
3430 EM
Country
Netherlands
Facility Name
Erasmus Medisch Centrum
City
Rotterdam
ZIP/Postal Code
3000 CA
Country
Netherlands
Facility Name
Auckland City Hospital
City
Auckland
ZIP/Postal Code
1023
Country
New Zealand
Facility Name
NZ Respiratory & Sleep Institute
City
Auckland
ZIP/Postal Code
1051
Country
New Zealand
Facility Name
University of Otago, Christchurch
City
Christchurch
ZIP/Postal Code
8011
Country
New Zealand
Facility Name
Waikato Hospital; Gastro Research
City
Hamilton
ZIP/Postal Code
3240
Country
New Zealand
Facility Name
Tauranga Hospital
City
Tauranga
ZIP/Postal Code
3143
Country
New Zealand
Facility Name
Helse Bergen HF Haukeland universitetssykehus; Hudavdelingen
City
Bergen
ZIP/Postal Code
5021
Country
Norway
Facility Name
Akershus universitetssykehus
City
Lørenskog
ZIP/Postal Code
1478
Country
Norway
Facility Name
Oslo University Hospital HF, Rikshospitalet
City
Oslo
ZIP/Postal Code
0424
Country
Norway
Facility Name
Centrum Medycyny Oddechowej Mroz sp. j.
City
Bia?ystok
ZIP/Postal Code
15-044
Country
Poland
Facility Name
Nasz Lekarz Osrodek Badan Klinicznych
City
Bydgoszcz
ZIP/Postal Code
85-312
Country
Poland
Facility Name
SPZOZ Uniwersytecki Szpital Kliniczny nr 1 im. Norberta Barlickiego Uniwersytetu Medycznego w Lodzi
City
Lodz
ZIP/Postal Code
90-153
Country
Poland
Facility Name
Hospital de Braga; Centro Clínico Académico (Piso 1, Ala E)
City
Braga
ZIP/Postal Code
4710-243
Country
Portugal
Facility Name
Centro Hospitalar do Alto Ave; EPE
City
Guimarães
ZIP/Postal Code
4835-044
Country
Portugal
Facility Name
Centro Hospitalar Universitario Lisboa Norte - Hospital Pulido Valente
City
Lisboa
ZIP/Postal Code
1769-001
Country
Portugal
Facility Name
CHVNG/E_Unidade 1; Servico de Pneumologia
City
Vila Nova de Gaia
ZIP/Postal Code
4434-502
Country
Portugal
Facility Name
National University Hospital
City
Singapore
ZIP/Postal Code
117599
Country
Singapore
Facility Name
Singapore General Hospital
City
Singapore
ZIP/Postal Code
169608
Country
Singapore
Facility Name
Tan Tock Seng Hospital; Oncology
City
Singapore
ZIP/Postal Code
308433
Country
Singapore
Facility Name
University of Cape Town Lung Institute; Lung Clinical Research
City
Cape Town
ZIP/Postal Code
7700
Country
South Africa
Facility Name
Vergelegen Medi-Clinic
City
Somerset West
ZIP/Postal Code
7130
Country
South Africa
Facility Name
HUA - Txagorritxu
City
Vitoria
State/Province
Alava
ZIP/Postal Code
01009
Country
Spain
Facility Name
Hospital Univ. Central de Asturias
City
Oviedo
State/Province
Asturias
ZIP/Postal Code
33006
Country
Spain
Facility Name
Hospital Universitario de Bellvitge
City
Hospitalet de Llobregat
State/Province
Barcelona
ZIP/Postal Code
08907
Country
Spain
Facility Name
Corporació Sanitaria Parc Taulí; Servicio de Neurología
City
Sabadell
State/Province
Barcelona
ZIP/Postal Code
08208
Country
Spain
Facility Name
Hospital Universitario Marques de Valdecilla
City
Santander
State/Province
Cantabria
ZIP/Postal Code
39008
Country
Spain
Facility Name
CHUS ? H. Clinico U. de Santiago
City
Santiago de Compostela
State/Province
LA Coruña
ZIP/Postal Code
15706
Country
Spain
Facility Name
Hospital Universitario del Henares
City
Coslada
State/Province
Madrid
ZIP/Postal Code
28850
Country
Spain
Facility Name
Hospital Galdakao-Usansolo
City
Galdakao
State/Province
Vizcaya
ZIP/Postal Code
48960
Country
Spain
Facility Name
Hospital de la Santa Creu i Sant Pau; Servicio de Neumologia
City
Barcelona
ZIP/Postal Code
08025
Country
Spain
Facility Name
Hospital Clinic I Provincial
City
Barcelona
ZIP/Postal Code
08036
Country
Spain
Facility Name
Hospital Germans Trias i Pujol
City
Barcelona
ZIP/Postal Code
08916
Country
Spain
Facility Name
Hospital Virgen de las Nieves; Servicio de Neumologia
City
Granada
ZIP/Postal Code
18014
Country
Spain
Facility Name
Hospital Universitario de la Princesa; Servicio de Aparato Digestivo
City
Madrid
ZIP/Postal Code
28006
Country
Spain
Facility Name
Clinica Universidad de Navarra ; Servicio de Farmacia
City
Madrid
ZIP/Postal Code
28027
Country
Spain
Facility Name
Universidad Autonoma de Madrid (UAM) - Hospital Universitario La Paz
City
Madrid
ZIP/Postal Code
28029
Country
Spain
Facility Name
Hospital Ramón y Cajal;Servicio de Neumología
City
Madrid
ZIP/Postal Code
28034
Country
Spain
Facility Name
Fundacion Jimenez Diaz-UTE
City
Madrid
ZIP/Postal Code
28040
Country
Spain
Facility Name
Hosp. Clinico San Carlos
City
Madrid
ZIP/Postal Code
28040
Country
Spain
Facility Name
Hospital Universitario 12 de Octubre
City
Madrid
ZIP/Postal Code
28041
Country
Spain
Facility Name
Hospital Clinico Universitario Virgen de la Victoria
City
Malaga
ZIP/Postal Code
29010
Country
Spain
Facility Name
Hospital Clinico Universitario de Salamanca
City
Salamanca
ZIP/Postal Code
37007
Country
Spain
Facility Name
Hospital Clinico Universitario de Valencia
City
Valencia
ZIP/Postal Code
46010
Country
Spain
Facility Name
Buddhist Tzu Chi Dalin General Hospital; Rheumatology
City
Chia-yi
ZIP/Postal Code
622
Country
Taiwan
Facility Name
Kaohsiung Medical University Hospital; Chung-Ho Memorial Hospital
City
Kaoshiung City
ZIP/Postal Code
807
Country
Taiwan
Facility Name
China Medical University Hospital
City
Taichung
ZIP/Postal Code
40447
Country
Taiwan
Facility Name
National Cheng Kung University Hospital
City
Tainan
ZIP/Postal Code
70457
Country
Taiwan
Facility Name
National Taiwan University Hospital
City
Taipei
ZIP/Postal Code
10002
Country
Taiwan
Facility Name
Far Eastern Memorial Hospital; Department of Clinical Pathology
City
Taipei
ZIP/Postal Code
220
Country
Taiwan
Facility Name
Veterans General Hospital - Taichung
City
Xitun Dist.
ZIP/Postal Code
40705
Country
Taiwan
Facility Name
Istanbul Universitesi Onkoloji Enstitüsü Hastanesi
City
?stanbul
ZIP/Postal Code
34093
Country
Turkey
Facility Name
Cukurova Universitesi Tip Fakultesi Balcali Hastanesi; Balcali
City
Adana
ZIP/Postal Code
1330
Country
Turkey
Facility Name
Ankara Universitesi Tip Fakultesi Hastaneleri - Cebeci Hastanesi
City
Ankara
ZIP/Postal Code
06620
Country
Turkey
Facility Name
Uludag Universitesi - Saglik Uygulama ve Arastirrma Merkezi
City
Bursa
ZIP/Postal Code
16059
Country
Turkey
Facility Name
Gaziantep Universitesi Tip Fakultesi
City
Gaziantep
ZIP/Postal Code
27310
Country
Turkey
Facility Name
Yedikule Gogus Hastaliklari ve Gogus Cerrahisi Egitim ve Arastirma Hastanesi
City
Istanbul
ZIP/Postal Code
34020
Country
Turkey
Facility Name
Ege Universitesi Tip Fakultesi Hastanesi
City
Izmir
ZIP/Postal Code
35100
Country
Turkey
Facility Name
Dokuz Eylul University Faculty of Medicine; Chest Diseases
City
Izmir
ZIP/Postal Code
35340
Country
Turkey
Facility Name
Kocaeli Universitesi Tip Fakultesi
City
Kocaeli
ZIP/Postal Code
41380
Country
Turkey
Facility Name
Marmara Universitesi Hastanesi Marmara University Hospital
City
Maltepe
ZIP/Postal Code
34854
Country
Turkey
Facility Name
Eriyes universitesi T?p Fakultesi Hastanesi
City
Melikgazi/Kayser
ZIP/Postal Code
38039
Country
Turkey
Facility Name
Mersin Universitesi Tip Fakultesi Hastanesi; Tibbi Onkoloji Birimi
City
Mersin
ZIP/Postal Code
33110
Country
Turkey
Facility Name
Akdeniz University Faculty of Medicine Department of Pulmonology
City
Muratpasa/Antalya
ZIP/Postal Code
07059
Country
Turkey
Facility Name
Koc Universitesi (KU) Tip Fakultesi (Koc University School of Medicine)
City
Sariyer
ZIP/Postal Code
34450
Country
Turkey
12. IPD Sharing Statement
Plan to Share IPD
Yes
IPD Sharing Plan Description
Qualified researchers may request access to individual patient level data through the clinical study data request platform (www.vivli.org). Further details on Roche's criteria for eligible studies are available here (https://vivli.org/ourmember/roche/). For further details on Roche's Global Policy on the Sharing of Clinical Information and how to request access to related clinical study documents, see here (https://www.roche.com/research_and_development/who_we_are_how_we_work/clinical_trials/our_commitment_to_data_sharing.htm).
Learn more about this trial
A Study to Evaluate Long Term Safety and Efficacy of Recombinant Human Pentraxin-2 (rhPTX-2; PRM-151) in Participants With Idiopathic Pulmonary Fibrosis
We'll reach out to this number within 24 hrs