Back to resultsRelationship Between Biological Profiles and Clinical Evolutions Within the Same Cluster COVID-19 (COVIDCOLLECT) (COVIDCOLLECT)
Primary Purpose
Covid19, Contact Case
Status
Unknown status
Phase
Not Applicable
Locations
France
Study Type
Interventional
Intervention
Biological collection with nasopharyngeal samples, saliva, blood, stool and urine
Sponsored by
About this trial
This is an interventional diagnostic trial for Covid19 focused on measuring SARS-CoV-2, COVID19, Confirmed case, Biological collection, contact case, cluster
Eligibility Criteria
Inclusion Criteria:
- Child or adult, no age limit
- Able to give informed consent to participate in research
- If a minor participant: consent of the legal representatives
- If confirmed case COVID-19 (symptomatic or asymptomatic): laboratory result confirming infection with SARS-CoV-2 by RT-PCR or by serology
- If contact case: people identified as a risk contact according to the criteria of the "Amélie.fr" health insurance
Exclusion Criteria:
- Subjects under tutorship, curatorship, deprived of liberty, safeguard of justice
- Refusal of the child
- Refusal of participation
Sites / Locations
- CHU de Clermont-Ferrand
Arms of the Study
Arm 1
Arm Type
Experimental
Arm Label
cohort
Arm Description
Biological collection with nasopharyngeal samples, saliva, blood, stool and urine
Outcomes
Primary Outcome Measures
Virological profile
Nasopharyngeal SARS-CoV-2 viral load at day 0 by RT-PCR (in log or ΔCT)
Virological profile
Nasopharyngeal SARS-CoV-2 viral load at day 0 by RT-PCR (in log or ΔCT)
Virological profile
Nasopharyngeal SARS-CoV-2 viral load at day 0 by RT-PCR (in log or ΔCT)
Virological profile (serology)
SARS-CoV-2 serology by enzyme-linked immunosorbent assays or magnetic chemiluminescence enzyme immunoassay (IgG and IgM titers)
Virological profile (serology)
SARS-CoV-2 serology by enzyme-linked immunosorbent assays or magnetic chemiluminescence enzyme immunoassay (IgG and IgM titers)
Virological profile (serology)
SARS-CoV-2 serology by enzyme-linked immunosorbent assays or magnetic chemiluminescence enzyme immunoassay (IgG and IgM titers)
Immunological profile with blood level for markers of inflammation (cytokine)
cytokine panel by flow cytometry or enzyme-linked immunosorbent assay in pg/mL
Immunological profile with blood level for markers of inflammation (cytokine)
cytokine panel by flow cytometry or enzyme-linked immunosorbent assay in pg/mL
Immunological profile with blood level for markers of inflammation (cytokine)
cytokine panel by flow cytometry or enzyme-linked immunosorbent assay in pg/mL
Immunological profile with blood level for markers of inflammation
markers on immune cell subpopulation by RT-PCR or flow cytometry in CT value or %
Immunological profile with blood level for markers of inflammation
markers on immune cell subpopulation by RT-PCR or flow cytometry in CT value or %
Immunological profile with blood level for markers of inflammation
markers on immune cell subpopulation by RT-PCR or flow cytometry in CT value or %
Biochemical profile by blood dosage of CRP
CRP in mg/l
Biochemical profile by blood dosage of CRP
CRP in mg/l
Biochemical profile by blood dosage of CRP
CRP in mg/l
Biochemical profile by blood dosage of CRP
CRP in mg/l
Biochemical profile by blood dosage of ASAT/ALAT
ASAT/ALAT in U/L
Biochemical profile by blood dosage of ASAT/ALAT
ASAT/ALAT in U/L
Biochemical profile by blood dosage of ASAT/ALAT
ASAT/ALAT in U/L
Biochemical profile by blood dosage of ASAT/ALAT
ASAT/ALAT in U/L
Biochemical profile by blood dosage of LDH
LDH in U/L
Biochemical profile by blood dosage of LDH
LDH in U/L
Biochemical profile by blood dosage of LDH
LDH in U/L
Biochemical profile by blood dosage of LDH
LDH in U/L
Biochemical profile by blood dosage of Lactate
Lactate in mg/l
Biochemical profile by blood dosage of Lactate
Lactate in mg/l
Biochemical profile by blood dosage of Lactate
Lactate in mg/l
Biochemical profile by blood dosage of Lactate
Lactate in mg/l
Biochemical profile by blood dosage of D-Dimer
D-Dimer in µg/L
Biochemical profile by blood dosage of D-Dimer
D-Dimer in µg/L
Biochemical profile by blood dosage of D-Dimer
D-Dimer in µg/L
Biochemical profile by blood dosage of D-Dimer
D-Dimer in µg/L
Biochemical profile by blood dosage of Troponin
Troponin in µg/L
Biochemical profile by blood dosage of Troponin
Troponin in µg/L
Biochemical profile by blood dosage of Troponin
Troponin in µg/L
Biochemical profile by blood dosage of Troponin
Troponin in µg/L
Biochemical profile by blood dosage of Ferritin
Ferritin in µg/L
Biochemical profile by blood dosage of Ferritin
Ferritin in µg/L
Biochemical profile by blood dosage of Ferritin
Ferritin in µg/L
Biochemical profile by blood dosage of RAGE
RAGE (receptor of advanced end glycation products) by enzyme-linked immunosorbent assays in pg/mg total protein
Biochemical profile by blood dosage of RAGE
RAGE (receptor of advanced end glycation products) by enzyme-linked immunosorbent assays in pg/mg total protein
Biochemical profile by blood dosage of RAGE
RAGE (receptor of advanced end glycation products) by enzyme-linked immunosorbent assays in pg/mg total protein
Biochemical profile by blood dosage of SUPAR
SUPAR (soluble urokinase plasminogen activator receptor) by enzyme-linked immunosorbent assays in pg/mg total protein
Biochemical profile by blood dosage of SUPAR
SUPAR (soluble urokinase plasminogen activator receptor) by enzyme-linked immunosorbent assays in pg/mg total protein
Biochemical profile by blood dosage of SUPAR
SUPAR (soluble urokinase plasminogen activator receptor) by enzyme-linked immunosorbent assays in pg/mg total protein
Haematological profile by blood dosage of leukocytes
leukocytes in Giga/L
Haematological profile by blood dosage of leukocytes
leukocytes in Giga/L
Haematological profile by blood dosage of leukocytes
leukocytes in Giga/L
Haematological profile by blood dosage of leukocytes
leukocytes in Giga/L
Haematological profile by blood dosage of Red blood cells
Red blood cells in Tera/L
Haematological profile by blood dosage of Red blood cells
Red blood cells in Tera/L
Haematological profile by blood dosage of Red blood cells
Red blood cells in Tera/L
Haematological profile by blood dosage of Red blood cells
Red blood cells in Tera/L
Haematological profile by blood dosage of Hemoglobin
Hemoglobin in g/dL
Haematological profile by blood dosage of Hemoglobin
Hemoglobin in g/dL
Haematological profile by blood dosage of Hemoglobin
Hemoglobin in g/dL
Haematological profile by blood dosage of Hemoglobin
Hemoglobin in g/dL
Haematological profile by blood dosage of Hematocrit
Hematocrit in %
Haematological profile by blood dosage of Hematocrit
Hematocrit in %
Haematological profile by blood dosage of Hematocrit
Hematocrit in %
Haematological profile by blood dosage of Hematocrit
Hematocrit in %
Haematological profile by blood dosage of Mean corpuscular volume
Mean corpuscular volume in fL
Haematological profile by blood dosage of Mean corpuscular volume
Mean corpuscular volume in fL
Haematological profile by blood dosage of Mean corpuscular volume
Mean corpuscular volume in fL
Haematological profile by blood dosage of Mean corpuscular volume
Mean corpuscular volume in fL
Haematological profile by blood dosage of Mean corpuscular hemoglobin
Mean corpuscular hemoglobin in pg
Haematological profile by blood dosage of Mean corpuscular hemoglobin
Mean corpuscular hemoglobin in pg
Haematological profile by blood dosage of Mean corpuscular hemoglobin
Mean corpuscular hemoglobin in pg
Haematological profile by blood dosage of Mean corpuscular hemoglobin
Mean corpuscular hemoglobin in pg
Haematological profile by blood dosage of average corpuscular concentration of haemoglobin
Average corpuscular concentration of haemoglobin in g/dL
Haematological profile by blood dosage of average corpuscular concentration of haemoglobin
Average corpuscular concentration of haemoglobin in g/dL
Haematological profile by blood dosage of average corpuscular concentration of haemoglobin
Average corpuscular concentration of haemoglobin in g/dL
Haematological profile by blood dosage of average corpuscular concentration of haemoglobin
Average corpuscular concentration of haemoglobin in g/dL
Haematological profile by blood dosage of polynuclear neutrophil
polynuclear neutrophil in Giga/L
Haematological profile by blood dosage of polynuclear neutrophil
polynuclear neutrophil in Giga/L
Haematological profile by blood dosage of polynuclear neutrophil
polynuclear neutrophil in Giga/L
Haematological profile by blood dosage of polynuclear neutrophil
polynuclear neutrophil in Giga/L
Haematological profile by blood dosage of polynuclear eosinophils
polynuclear eosinophils in Giga/L
Haematological profile by blood dosage of polynuclear eosinophils
polynuclear eosinophils in Giga/L
Haematological profile by blood dosage of polynuclear eosinophils
polynuclear eosinophils in Giga/L
Haematological profile by blood dosage of polynuclear eosinophils
polynuclear eosinophils in Giga/L
Haematological profile by blood dosage of polynuclear basophils
polynuclear basophils in Giga/L
Haematological profile by blood dosage of polynuclear basophils
polynuclear basophils in Giga/L
Haematological profile by blood dosage of polynuclear basophils
polynuclear basophils in Giga/L
Haematological profile by blood dosage of polynuclear basophils
polynuclear basophils in Giga/L
Haematological profile by blood dosage of lymphocytes
lymphocytes in Giga/L
Haematological profile by blood dosage of lymphocytes
lymphocytes in Giga/L
Haematological profile by blood dosage of lymphocytes
lymphocytes in Giga/L
Haematological profile by blood dosage of lymphocytes
lymphocytes in Giga/L
Haematological profile by blood dosage of monocytes
monocytes in Giga/L
Haematological profile by blood dosage of monocytes
monocytes in Giga/L
Haematological profile by blood dosage of monocytes
monocytes in Giga/L
Haematological profile by blood dosage of monocytes
monocytes in Giga/L
Haematological profile by blood dosage of platelets
platelets in Giga/L
Haematological profile by blood dosage of platelets
platelets in Giga/L
Haematological profile by blood dosage of platelets
platelets in Giga/L
Haematological profile by blood dosage of platelets
platelets in Giga/L
Haematological profile by blood dosage of activated partial thromboplastin time
activated partial thromboplastin time in second/witness
Haematological profile by blood dosage of activated partial thromboplastin time
activated partial thromboplastin time in second/witness
Haematological profile by blood dosage of activated partial thromboplastin time
activated partial thromboplastin time in second/witness
Haematological profile by blood dosage of activated partial thromboplastin time
activated partial thromboplastin time in second/witness
Haematological profile by blood dosage of fibrinogen
fibrinogen in g/L
Haematological profile by blood dosage of fibrinogen
fibrinogen in g/L
Haematological profile by blood dosage of fibrinogen
fibrinogen in g/L
Haematological profile by blood dosage of fibrinogen
fibrinogen in g/L
Haematological profile by blood dosage of factor V
factor V in %
Haematological profile by blood dosage of factor V
factor V in %
Haematological profile by blood dosage of factor V
factor V in %
Haematological profile by blood dosage of factor V
factor V in %
Secondary Outcome Measures
SARS-CoV-2 salivary viral load
RT-PCR SARS-CoV-2 on saliva in ΔCT value or log10 copies per mL
SARS-CoV-2 salivary viral load
RT-PCR SARS-CoV-2 on saliva in ΔCT value or log10 copies per mL
SARS-CoV-2 salivary viral load
RT-PCR SARS-CoV-2 on saliva in ΔCT value or log10 copies per mL
Comparison of viral sequences
bioinformatic and statistical analyzes of viral sequences (arbitrary unit and p-values)
Comparison of viral sequences
bioinformatic and statistical analyzes of viral sequences (arbitrary unit and p-values)
Comparison of viral sequences
bioinformatic and statistical analyzes of viral sequences (arbitrary unit and p-values)
microbiota analysis
bioinformatic and statistical analyzes of microbiota (arbitrary unit and p-values)
microbiota analysis
bioinformatic and statistical analyzes of microbiota (arbitrary unit and p-values)
microbiota analysis
bioinformatic and statistical analyzes of microbiota (arbitrary unit and p-values)
environmental and societal factors (EPICE)
EPICE score (Assessment of precariousness and health inequalities in examination centers Health) at day 0 from 0 to 100
environmental and societal factors
eating habits
environmental and societal factors
eating habits
environmental and societal factors
eating habits
environmental and societal factors
eating habits
environmental and societal factors (SF-36)
SF-36 score (quality of life by Gardenal O) from 0 to 100
environmental and societal factors (SF-36)
SF-36 score (quality of life by Gardenal O) from 0 to 100
environmental and societal factors (SF-36)
SF-36 score (quality of life by Gardenal O) from 0 to 100
environmental and societal factors (SF-36)
SF-36 score (quality of life by Gardenal O) from 0 to 100
environmental and societal factors (Physical activity)
Physical activity score (by J. Ricci et L. Gagnon test for adults and ActiFitY test for children) from 0 to 100
environmental and societal factors (Physical activity)
Physical activity score (by J. Ricci et L. Gagnon test for adults and ActiFitY test for children) from 0 to 100
environmental and societal factors (Physical activity)
Physical activity score (by J. Ricci et L. Gagnon test for adults and ActiFitY test for children) from 0 to 100
environmental and societal factors (Physical activity)
Physical activity score (by J. Ricci et L. Gagnon test for adults and ActiFitY test for children) from 0 to 100
body weight
body weight in kg
body weight
body weight in kg
body weight
body weight in kg
body weight
body weight in kg
oxygen saturation
oxygen saturation in %
oxygen saturation
oxygen saturation in %
oxygen saturation
oxygen saturation in %
oxygen saturation
oxygen saturation in %
Respiratory rate
Respiratory rate per minute
Respiratory rate
Respiratory rate per minute
Respiratory rate
Respiratory rate per minute
Respiratory rate
Respiratory rate per minute
cardiac frequency
cardiac frequency per minute
cardiac frequency
cardiac frequency per minute
cardiac frequency
cardiac frequency per minute
cardiac frequency
cardiac frequency per minute
lung damage
Lung damage on auscultation in terms of presence/absence
lung damage
Lung damage on auscultation in terms of presence/absence
lung damage
Lung damage on auscultation in terms of presence/absence
lung damage
Lung damage on auscultation in terms of presence/absence
lung evolution
CT san in terms of normal/abnormal (children and pregnant women not concerned)
blood pressure
Dysatolic/systolic blood pressure in mmHg
blood pressure
Dysatolic/systolic blood pressure in mmHg
blood pressure
Dysatolic/systolic blood pressure in mmHg
blood pressure
Dysatolic/systolic blood pressure in mmHg
body temperature
Body temperature in °C
body temperature
Body temperature in °C
body temperature
Body temperature in °C
body temperature
Body temperature in °C
clinical exam (skin)
Skin mottling in terms of presence/absence
clinical exam (skin)
Skin mottling in terms of presence/absence
clinical exam (skin)
Skin mottling in terms of presence/absence
clinical exam (skin)
Skin mottling in terms of presence/absence
clinical exam (polypnea)
polypnea in terms of presence/absence
clinical exam (polypnea)
polypnea in terms of presence/absence
clinical exam (polypnea)
polypnea in terms of presence/absence
clinical exam (polypnea)
polypnea in terms of presence/absence
denutrition
denutrition in terms of presence/absence
denutrition
denutrition in terms of presence/absence
denutrition
denutrition in terms of presence/absence
denutrition
denutrition in terms of presence/absence
Antibiotic treatment
Antibiotic treatment in terms of presence/absence with precision if necessary
Antibiotic treatment
Antibiotic treatment in terms of presence/absence with precision if necessary
Antibiotic treatment
Antibiotic treatment in terms of presence/absence with precision if necessary
Antibiotic treatment
Antibiotic treatment in terms of presence/absence with precision if necessary
Steroidal anti-inflammatory treatment
Steroidal anti-inflammatory treatment in terms of presence/absence with precision if necessary
Steroidal anti-inflammatory treatment
Steroidal anti-inflammatory treatment in terms of presence/absence with precision if necessary
Steroidal anti-inflammatory treatment
Steroidal anti-inflammatory treatment in terms of presence/absence with precision if necessary
Steroidal anti-inflammatory treatment
Steroidal anti-inflammatory treatment in terms of presence/absence with precision if necessary
Anti-diabetic treatment
Anti-diabetic treatment in terms of presence/absence with precision if necessary
Anti-diabetic treatment
Anti-diabetic treatment in terms of presence/absence with precision if necessary
Anti-diabetic treatment
Anti-diabetic treatment in terms of presence/absence with precision if necessary
Anti-diabetic treatment
Anti-diabetic treatment in terms of presence/absence with precision if necessary
Gastric protector treatment
Gastric protector treatment in terms of presence/absence with precision if necessary
Gastric protector treatment
Gastric protector treatment in terms of presence/absence with precision if necessary
Gastric protector treatment
Gastric protector treatment in terms of presence/absence with precision if necessary
Gastric protector treatment
Gastric protector treatment in terms of presence/absence with precision if necessary
chills
chills in terms of presence/absence
chills
chills in terms of presence/absence
chills
chills in terms of presence/absence
chills
chills in terms of presence/absence
Myalgia
Myalgia in terms of presence/absence
Myalgia
Myalgia in terms of presence/absence
Myalgia
Myalgia in terms of presence/absence
Myalgia
Myalgia in terms of presence/absence
Anorexia
Anorexia in terms of presence/absence
Anorexia
Anorexia in terms of presence/absence
Anorexia
Anorexia in terms of presence/absence
Anorexia
Anorexia in terms of presence/absence
Rhinitis
Rhinitis in terms of presence/absence
Rhinitis
Rhinitis in terms of presence/absence
Rhinitis
Rhinitis in terms of presence/absence
Rhinitis
Rhinitis in terms of presence/absence
Confusion
Confusion in terms of presence/absence
Confusion
Confusion in terms of presence/absence
Confusion
Confusion in terms of presence/absence
Confusion
Confusion in terms of presence/absence
Asthenia
Asthenia in terms of presence/absence
Asthenia
Asthenia in terms of presence/absence
Asthenia
Asthenia in terms of presence/absence
Asthenia
Asthenia in terms of presence/absence
Falls at home
Falls at home in terms of presence/absence
Falls at home
Falls at home in terms of presence/absence
Falls at home
Falls at home in terms of presence/absence
Falls at home
Falls at home in terms of presence/absence
Insomnia
Insomnia in terms of presence/absence
Insomnia
Insomnia in terms of presence/absence
Insomnia
Insomnia in terms of presence/absence
Insomnia
Insomnia in terms of presence/absence
Angina
Angina in terms of presence/absence
Angina
Angina in terms of presence/absence
Angina
Angina in terms of presence/absence
Angina
Angina in terms of presence/absence
Ageusia
Ageusia in terms of presence/absence
Ageusia
Ageusia in terms of presence/absence
Ageusia
Ageusia in terms of presence/absence
Ageusia
Ageusia in terms of presence/absence
Respiratory complaints
Respiratory complaints in term of SRIpr score from 0 to 100
Respiratory complaints
Respiratory complaints in term of SRIpr score from 0 to 100
Respiratory complaints
Respiratory complaints in term of SRIpr score from 0 to 100
Respiratory complaints
Respiratory complaints in term of SRIpr score from 0 to 100
Respiratory complaints
Respiratory complaints in term of SRIpr score from 0 to 100
Respiratory complaints
Respiratory complaints in term of SRIpr score from 0 to 100
Respiratory complaints
Respiratory complaints in term of SRIpr score from 0 to 100
Respiratory complaints
Respiratory complaints in term of SRIpr score from 0 to 100
transmission rate
Rate of viral transmission determine by bioinformatic and statistical analyzes in %
transmission rate
Rate of viral transmission determine by bioinformatic and statistical analyzes in %
transmission rate
Rate of viral transmission determine by bioinformatic and statistical analyzes in %
prolonged viral shedding
Prolonged viral shedding evaluate by RT-PCR (CT value or log10 copies per mL)
Full Information
NCT ID
NCT04597736
First Posted
October 2, 2020
Last Updated
October 21, 2020
Sponsor
University Hospital, Clermont-Ferrand
1. Study Identification
Unique Protocol Identification Number
NCT04597736
Brief Title
Relationship Between Biological Profiles and Clinical Evolutions Within the Same Cluster COVID-19 (COVIDCOLLECT)
Acronym
COVIDCOLLECT
Official Title
Biological Collection for the Study of the Relationship Between the Biological Profiles Observed and the Clinical Evolutions Within the Same Cluster of Transmission of the Coronavirus SARS-CoV-2
Study Type
Interventional
2. Study Status
Record Verification Date
September 2020
Overall Recruitment Status
Unknown status
Study Start Date
November 2020 (Anticipated)
Primary Completion Date
November 2021 (Anticipated)
Study Completion Date
February 2022 (Anticipated)
3. Sponsor/Collaborators
Responsible Party, by Official Title
Sponsor
Name of the Sponsor
University Hospital, Clermont-Ferrand
4. Oversight
Studies a U.S. FDA-regulated Drug Product
No
Studies a U.S. FDA-regulated Device Product
No
Data Monitoring Committee
No
5. Study Description
Brief Summary
The hypothesis is that from a cluster defined by a confirmed positive case of COVID-19 and its contact cases, it is possible to study the different expressions and clinical evolutions of COVID-19 infection and to explore the biological profiles related to the observed clinical history. Certain biological determinants (virological, immunological, microbological or gentic) could indeed be correlated with the clinical presentation and/or be useful for personalized care.
The main objective is to study the relationship between the biological profiles observed and the clinical evolutions within the same cluster of transmission of the coronavirus SARS-CoV-2 (positive COVID-19 cases and contact subjects).
Detailed Description
Subjects with a COVID-19 infection and thei contact cases (identification according to health insurance criteria, see "Améli.fr") will be offered a clinical evaluation and the takin of biological samples, whether they are hospitalized or via the outpatient screening channel.
For the main objective: during the D0 visit, the subjects who agreed to participate in the study will have a clinical evaluation according to a standardized questionnaire and a nasopharyngeal swab, saliva, blood, stool and urine.
For secondary objectives : longitudinal follow-up will be carried out for 21 days, for index cases and contact cases, whether they have a positive or negative RT-PCR test on D0. A final consultation will be carried out at M3. Nasopharyngeal samples, saliva, blood, stool and urine will be taken on D10 and D21. A blood test will be taken at M3 to carry out a COVID-19 serology.
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Covid19, Contact Case
Keywords
SARS-CoV-2, COVID19, Confirmed case, Biological collection, contact case, cluster
7. Study Design
Primary Purpose
Diagnostic
Study Phase
Not Applicable
Interventional Study Model
Single Group Assignment
Masking
None (Open Label)
Allocation
N/A
Enrollment
100 (Anticipated)
8. Arms, Groups, and Interventions
Arm Title
cohort
Arm Type
Experimental
Arm Description
Biological collection with nasopharyngeal samples, saliva, blood, stool and urine
Intervention Type
Biological
Intervention Name(s)
Biological collection with nasopharyngeal samples, saliva, blood, stool and urine
Intervention Description
Subjects with a COVID-19 infection and their contact cases (identification according to health insurance criteria, see "Améli.fr") will be offered a clinical evaluation and the takin of biological samples, whether they are hospitalized or via the outpatient screening channel.
For the main objective: during the Day0 visit, the subjects who agreed to participate in the study will have a clinical evaluation according to a standardized questionnaire and a nasopharyngeal swab, saliva, blood, stool and urine.
For secondary objectives : longitudinal follow-up will be carried out for 21 days, for index cases and contact cases, whether they have a positive or negative RT-PCR test on D0. A final consultation will be carried out at M3. Nasopharyngeal samples, saliva, blood, stool and urine will be taken on D10 and D21. A blood test will be taken at M3 to carry out a COVID-19 serology.
Primary Outcome Measure Information:
Title
Virological profile
Description
Nasopharyngeal SARS-CoV-2 viral load at day 0 by RT-PCR (in log or ΔCT)
Time Frame
Day 0
Title
Virological profile
Description
Nasopharyngeal SARS-CoV-2 viral load at day 0 by RT-PCR (in log or ΔCT)
Time Frame
Day 10
Title
Virological profile
Description
Nasopharyngeal SARS-CoV-2 viral load at day 0 by RT-PCR (in log or ΔCT)
Time Frame
Day 21
Title
Virological profile (serology)
Description
SARS-CoV-2 serology by enzyme-linked immunosorbent assays or magnetic chemiluminescence enzyme immunoassay (IgG and IgM titers)
Time Frame
Day 0
Title
Virological profile (serology)
Description
SARS-CoV-2 serology by enzyme-linked immunosorbent assays or magnetic chemiluminescence enzyme immunoassay (IgG and IgM titers)
Time Frame
Day 10
Title
Virological profile (serology)
Description
SARS-CoV-2 serology by enzyme-linked immunosorbent assays or magnetic chemiluminescence enzyme immunoassay (IgG and IgM titers)
Time Frame
Day 21
Title
Immunological profile with blood level for markers of inflammation (cytokine)
Description
cytokine panel by flow cytometry or enzyme-linked immunosorbent assay in pg/mL
Time Frame
Day 0
Title
Immunological profile with blood level for markers of inflammation (cytokine)
Description
cytokine panel by flow cytometry or enzyme-linked immunosorbent assay in pg/mL
Time Frame
Day 10
Title
Immunological profile with blood level for markers of inflammation (cytokine)
Description
cytokine panel by flow cytometry or enzyme-linked immunosorbent assay in pg/mL
Time Frame
Day 21
Title
Immunological profile with blood level for markers of inflammation
Description
markers on immune cell subpopulation by RT-PCR or flow cytometry in CT value or %
Time Frame
Day 0
Title
Immunological profile with blood level for markers of inflammation
Description
markers on immune cell subpopulation by RT-PCR or flow cytometry in CT value or %
Time Frame
Day 10
Title
Immunological profile with blood level for markers of inflammation
Description
markers on immune cell subpopulation by RT-PCR or flow cytometry in CT value or %
Time Frame
Day 21
Title
Biochemical profile by blood dosage of CRP
Description
CRP in mg/l
Time Frame
Day 0
Title
Biochemical profile by blood dosage of CRP
Description
CRP in mg/l
Time Frame
Day 10
Title
Biochemical profile by blood dosage of CRP
Description
CRP in mg/l
Time Frame
Day 21
Title
Biochemical profile by blood dosage of CRP
Description
CRP in mg/l
Time Frame
Day 90
Title
Biochemical profile by blood dosage of ASAT/ALAT
Description
ASAT/ALAT in U/L
Time Frame
Day 0
Title
Biochemical profile by blood dosage of ASAT/ALAT
Description
ASAT/ALAT in U/L
Time Frame
Day 10
Title
Biochemical profile by blood dosage of ASAT/ALAT
Description
ASAT/ALAT in U/L
Time Frame
Day 21
Title
Biochemical profile by blood dosage of ASAT/ALAT
Description
ASAT/ALAT in U/L
Time Frame
Day 90
Title
Biochemical profile by blood dosage of LDH
Description
LDH in U/L
Time Frame
Day 0
Title
Biochemical profile by blood dosage of LDH
Description
LDH in U/L
Time Frame
Day 10
Title
Biochemical profile by blood dosage of LDH
Description
LDH in U/L
Time Frame
Day 21
Title
Biochemical profile by blood dosage of LDH
Description
LDH in U/L
Time Frame
Day 90
Title
Biochemical profile by blood dosage of Lactate
Description
Lactate in mg/l
Time Frame
Day 0
Title
Biochemical profile by blood dosage of Lactate
Description
Lactate in mg/l
Time Frame
Day 10
Title
Biochemical profile by blood dosage of Lactate
Description
Lactate in mg/l
Time Frame
Day 21
Title
Biochemical profile by blood dosage of Lactate
Description
Lactate in mg/l
Time Frame
Day 90
Title
Biochemical profile by blood dosage of D-Dimer
Description
D-Dimer in µg/L
Time Frame
Day 0
Title
Biochemical profile by blood dosage of D-Dimer
Description
D-Dimer in µg/L
Time Frame
Day 10
Title
Biochemical profile by blood dosage of D-Dimer
Description
D-Dimer in µg/L
Time Frame
Day 21
Title
Biochemical profile by blood dosage of D-Dimer
Description
D-Dimer in µg/L
Time Frame
Day 90
Title
Biochemical profile by blood dosage of Troponin
Description
Troponin in µg/L
Time Frame
Day 0
Title
Biochemical profile by blood dosage of Troponin
Description
Troponin in µg/L
Time Frame
Day 10
Title
Biochemical profile by blood dosage of Troponin
Description
Troponin in µg/L
Time Frame
Day 21
Title
Biochemical profile by blood dosage of Troponin
Description
Troponin in µg/L
Time Frame
Day 90
Title
Biochemical profile by blood dosage of Ferritin
Description
Ferritin in µg/L
Time Frame
Day 0
Title
Biochemical profile by blood dosage of Ferritin
Description
Ferritin in µg/L
Time Frame
Day 10
Title
Biochemical profile by blood dosage of Ferritin
Description
Ferritin in µg/L
Time Frame
Day 21
Title
Biochemical profile by blood dosage of RAGE
Description
RAGE (receptor of advanced end glycation products) by enzyme-linked immunosorbent assays in pg/mg total protein
Time Frame
Day 0
Title
Biochemical profile by blood dosage of RAGE
Description
RAGE (receptor of advanced end glycation products) by enzyme-linked immunosorbent assays in pg/mg total protein
Time Frame
Day 10
Title
Biochemical profile by blood dosage of RAGE
Description
RAGE (receptor of advanced end glycation products) by enzyme-linked immunosorbent assays in pg/mg total protein
Time Frame
Day 21
Title
Biochemical profile by blood dosage of SUPAR
Description
SUPAR (soluble urokinase plasminogen activator receptor) by enzyme-linked immunosorbent assays in pg/mg total protein
Time Frame
Day 0
Title
Biochemical profile by blood dosage of SUPAR
Description
SUPAR (soluble urokinase plasminogen activator receptor) by enzyme-linked immunosorbent assays in pg/mg total protein
Time Frame
Day 10
Title
Biochemical profile by blood dosage of SUPAR
Description
SUPAR (soluble urokinase plasminogen activator receptor) by enzyme-linked immunosorbent assays in pg/mg total protein
Time Frame
Day 21
Title
Haematological profile by blood dosage of leukocytes
Description
leukocytes in Giga/L
Time Frame
Day 0
Title
Haematological profile by blood dosage of leukocytes
Description
leukocytes in Giga/L
Time Frame
Day 10
Title
Haematological profile by blood dosage of leukocytes
Description
leukocytes in Giga/L
Time Frame
Day 21
Title
Haematological profile by blood dosage of leukocytes
Description
leukocytes in Giga/L
Time Frame
Day 90
Title
Haematological profile by blood dosage of Red blood cells
Description
Red blood cells in Tera/L
Time Frame
Day 0
Title
Haematological profile by blood dosage of Red blood cells
Description
Red blood cells in Tera/L
Time Frame
Day 10
Title
Haematological profile by blood dosage of Red blood cells
Description
Red blood cells in Tera/L
Time Frame
Day 21
Title
Haematological profile by blood dosage of Red blood cells
Description
Red blood cells in Tera/L
Time Frame
Day 90
Title
Haematological profile by blood dosage of Hemoglobin
Description
Hemoglobin in g/dL
Time Frame
Day 0
Title
Haematological profile by blood dosage of Hemoglobin
Description
Hemoglobin in g/dL
Time Frame
Day 10
Title
Haematological profile by blood dosage of Hemoglobin
Description
Hemoglobin in g/dL
Time Frame
Day 21
Title
Haematological profile by blood dosage of Hemoglobin
Description
Hemoglobin in g/dL
Time Frame
Day 90
Title
Haematological profile by blood dosage of Hematocrit
Description
Hematocrit in %
Time Frame
Day 0
Title
Haematological profile by blood dosage of Hematocrit
Description
Hematocrit in %
Time Frame
Day 10
Title
Haematological profile by blood dosage of Hematocrit
Description
Hematocrit in %
Time Frame
Day 21
Title
Haematological profile by blood dosage of Hematocrit
Description
Hematocrit in %
Time Frame
Day 90
Title
Haematological profile by blood dosage of Mean corpuscular volume
Description
Mean corpuscular volume in fL
Time Frame
Day 0
Title
Haematological profile by blood dosage of Mean corpuscular volume
Description
Mean corpuscular volume in fL
Time Frame
Day 10
Title
Haematological profile by blood dosage of Mean corpuscular volume
Description
Mean corpuscular volume in fL
Time Frame
Day 21
Title
Haematological profile by blood dosage of Mean corpuscular volume
Description
Mean corpuscular volume in fL
Time Frame
Day 90
Title
Haematological profile by blood dosage of Mean corpuscular hemoglobin
Description
Mean corpuscular hemoglobin in pg
Time Frame
Day 0
Title
Haematological profile by blood dosage of Mean corpuscular hemoglobin
Description
Mean corpuscular hemoglobin in pg
Time Frame
Day 10
Title
Haematological profile by blood dosage of Mean corpuscular hemoglobin
Description
Mean corpuscular hemoglobin in pg
Time Frame
Day 21
Title
Haematological profile by blood dosage of Mean corpuscular hemoglobin
Description
Mean corpuscular hemoglobin in pg
Time Frame
Day 90
Title
Haematological profile by blood dosage of average corpuscular concentration of haemoglobin
Description
Average corpuscular concentration of haemoglobin in g/dL
Time Frame
Day 0
Title
Haematological profile by blood dosage of average corpuscular concentration of haemoglobin
Description
Average corpuscular concentration of haemoglobin in g/dL
Time Frame
Day 10
Title
Haematological profile by blood dosage of average corpuscular concentration of haemoglobin
Description
Average corpuscular concentration of haemoglobin in g/dL
Time Frame
Day 21
Title
Haematological profile by blood dosage of average corpuscular concentration of haemoglobin
Description
Average corpuscular concentration of haemoglobin in g/dL
Time Frame
Day 90
Title
Haematological profile by blood dosage of polynuclear neutrophil
Description
polynuclear neutrophil in Giga/L
Time Frame
Day 0
Title
Haematological profile by blood dosage of polynuclear neutrophil
Description
polynuclear neutrophil in Giga/L
Time Frame
Day 10
Title
Haematological profile by blood dosage of polynuclear neutrophil
Description
polynuclear neutrophil in Giga/L
Time Frame
Day 21
Title
Haematological profile by blood dosage of polynuclear neutrophil
Description
polynuclear neutrophil in Giga/L
Time Frame
Day 90
Title
Haematological profile by blood dosage of polynuclear eosinophils
Description
polynuclear eosinophils in Giga/L
Time Frame
Day 0
Title
Haematological profile by blood dosage of polynuclear eosinophils
Description
polynuclear eosinophils in Giga/L
Time Frame
Day 10
Title
Haematological profile by blood dosage of polynuclear eosinophils
Description
polynuclear eosinophils in Giga/L
Time Frame
Day 21
Title
Haematological profile by blood dosage of polynuclear eosinophils
Description
polynuclear eosinophils in Giga/L
Time Frame
Day 90
Title
Haematological profile by blood dosage of polynuclear basophils
Description
polynuclear basophils in Giga/L
Time Frame
Day 0
Title
Haematological profile by blood dosage of polynuclear basophils
Description
polynuclear basophils in Giga/L
Time Frame
Day 10
Title
Haematological profile by blood dosage of polynuclear basophils
Description
polynuclear basophils in Giga/L
Time Frame
Day 21
Title
Haematological profile by blood dosage of polynuclear basophils
Description
polynuclear basophils in Giga/L
Time Frame
Day 90
Title
Haematological profile by blood dosage of lymphocytes
Description
lymphocytes in Giga/L
Time Frame
Day 0
Title
Haematological profile by blood dosage of lymphocytes
Description
lymphocytes in Giga/L
Time Frame
Day 10
Title
Haematological profile by blood dosage of lymphocytes
Description
lymphocytes in Giga/L
Time Frame
Day 21
Title
Haematological profile by blood dosage of lymphocytes
Description
lymphocytes in Giga/L
Time Frame
Day 90
Title
Haematological profile by blood dosage of monocytes
Description
monocytes in Giga/L
Time Frame
Day 90
Title
Haematological profile by blood dosage of monocytes
Description
monocytes in Giga/L
Time Frame
Day 0
Title
Haematological profile by blood dosage of monocytes
Description
monocytes in Giga/L
Time Frame
Day 10
Title
Haematological profile by blood dosage of monocytes
Description
monocytes in Giga/L
Time Frame
Day 21
Title
Haematological profile by blood dosage of platelets
Description
platelets in Giga/L
Time Frame
Day 0
Title
Haematological profile by blood dosage of platelets
Description
platelets in Giga/L
Time Frame
Day 10
Title
Haematological profile by blood dosage of platelets
Description
platelets in Giga/L
Time Frame
Day 21
Title
Haematological profile by blood dosage of platelets
Description
platelets in Giga/L
Time Frame
Day 90
Title
Haematological profile by blood dosage of activated partial thromboplastin time
Description
activated partial thromboplastin time in second/witness
Time Frame
Day 0
Title
Haematological profile by blood dosage of activated partial thromboplastin time
Description
activated partial thromboplastin time in second/witness
Time Frame
Day 10
Title
Haematological profile by blood dosage of activated partial thromboplastin time
Description
activated partial thromboplastin time in second/witness
Time Frame
Day 21
Title
Haematological profile by blood dosage of activated partial thromboplastin time
Description
activated partial thromboplastin time in second/witness
Time Frame
Day 90
Title
Haematological profile by blood dosage of fibrinogen
Description
fibrinogen in g/L
Time Frame
Day 0
Title
Haematological profile by blood dosage of fibrinogen
Description
fibrinogen in g/L
Time Frame
Day 10
Title
Haematological profile by blood dosage of fibrinogen
Description
fibrinogen in g/L
Time Frame
Day 21
Title
Haematological profile by blood dosage of fibrinogen
Description
fibrinogen in g/L
Time Frame
Day 90
Title
Haematological profile by blood dosage of factor V
Description
factor V in %
Time Frame
Day 0
Title
Haematological profile by blood dosage of factor V
Description
factor V in %
Time Frame
Day 10
Title
Haematological profile by blood dosage of factor V
Description
factor V in %
Time Frame
Day 21
Title
Haematological profile by blood dosage of factor V
Description
factor V in %
Time Frame
Day 90
Secondary Outcome Measure Information:
Title
SARS-CoV-2 salivary viral load
Description
RT-PCR SARS-CoV-2 on saliva in ΔCT value or log10 copies per mL
Time Frame
Day 0
Title
SARS-CoV-2 salivary viral load
Description
RT-PCR SARS-CoV-2 on saliva in ΔCT value or log10 copies per mL
Time Frame
Day 10
Title
SARS-CoV-2 salivary viral load
Description
RT-PCR SARS-CoV-2 on saliva in ΔCT value or log10 copies per mL
Time Frame
Day 21
Title
Comparison of viral sequences
Description
bioinformatic and statistical analyzes of viral sequences (arbitrary unit and p-values)
Time Frame
Day 0
Title
Comparison of viral sequences
Description
bioinformatic and statistical analyzes of viral sequences (arbitrary unit and p-values)
Time Frame
Day 10
Title
Comparison of viral sequences
Description
bioinformatic and statistical analyzes of viral sequences (arbitrary unit and p-values)
Time Frame
Day 21
Title
microbiota analysis
Description
bioinformatic and statistical analyzes of microbiota (arbitrary unit and p-values)
Time Frame
Day 0
Title
microbiota analysis
Description
bioinformatic and statistical analyzes of microbiota (arbitrary unit and p-values)
Time Frame
Day 10
Title
microbiota analysis
Description
bioinformatic and statistical analyzes of microbiota (arbitrary unit and p-values)
Time Frame
Day 21
Title
environmental and societal factors (EPICE)
Description
EPICE score (Assessment of precariousness and health inequalities in examination centers Health) at day 0 from 0 to 100
Time Frame
Day 0
Title
environmental and societal factors
Description
eating habits
Time Frame
Day 0
Title
environmental and societal factors
Description
eating habits
Time Frame
day 10
Title
environmental and societal factors
Description
eating habits
Time Frame
day 21
Title
environmental and societal factors
Description
eating habits
Time Frame
day 90
Title
environmental and societal factors (SF-36)
Description
SF-36 score (quality of life by Gardenal O) from 0 to 100
Time Frame
Day 0
Title
environmental and societal factors (SF-36)
Description
SF-36 score (quality of life by Gardenal O) from 0 to 100
Time Frame
day 10
Title
environmental and societal factors (SF-36)
Description
SF-36 score (quality of life by Gardenal O) from 0 to 100
Time Frame
day 21
Title
environmental and societal factors (SF-36)
Description
SF-36 score (quality of life by Gardenal O) from 0 to 100
Time Frame
day 90
Title
environmental and societal factors (Physical activity)
Description
Physical activity score (by J. Ricci et L. Gagnon test for adults and ActiFitY test for children) from 0 to 100
Time Frame
Day 0
Title
environmental and societal factors (Physical activity)
Description
Physical activity score (by J. Ricci et L. Gagnon test for adults and ActiFitY test for children) from 0 to 100
Time Frame
day 10
Title
environmental and societal factors (Physical activity)
Description
Physical activity score (by J. Ricci et L. Gagnon test for adults and ActiFitY test for children) from 0 to 100
Time Frame
day 21
Title
environmental and societal factors (Physical activity)
Description
Physical activity score (by J. Ricci et L. Gagnon test for adults and ActiFitY test for children) from 0 to 100
Time Frame
day 90
Title
body weight
Description
body weight in kg
Time Frame
Day 0
Title
body weight
Description
body weight in kg
Time Frame
day 10
Title
body weight
Description
body weight in kg
Time Frame
day 21
Title
body weight
Description
body weight in kg
Time Frame
day 90
Title
oxygen saturation
Description
oxygen saturation in %
Time Frame
Day 0
Title
oxygen saturation
Description
oxygen saturation in %
Time Frame
day 10
Title
oxygen saturation
Description
oxygen saturation in %
Time Frame
day 21
Title
oxygen saturation
Description
oxygen saturation in %
Time Frame
day 90
Title
Respiratory rate
Description
Respiratory rate per minute
Time Frame
Day 0
Title
Respiratory rate
Description
Respiratory rate per minute
Time Frame
day 10
Title
Respiratory rate
Description
Respiratory rate per minute
Time Frame
day 21
Title
Respiratory rate
Description
Respiratory rate per minute
Time Frame
day 90
Title
cardiac frequency
Description
cardiac frequency per minute
Time Frame
Day 0
Title
cardiac frequency
Description
cardiac frequency per minute
Time Frame
day 10
Title
cardiac frequency
Description
cardiac frequency per minute
Time Frame
day 21
Title
cardiac frequency
Description
cardiac frequency per minute
Time Frame
day 90
Title
lung damage
Description
Lung damage on auscultation in terms of presence/absence
Time Frame
Day 0
Title
lung damage
Description
Lung damage on auscultation in terms of presence/absence
Time Frame
day 10
Title
lung damage
Description
Lung damage on auscultation in terms of presence/absence
Time Frame
day 21
Title
lung damage
Description
Lung damage on auscultation in terms of presence/absence
Time Frame
day 90
Title
lung evolution
Description
CT san in terms of normal/abnormal (children and pregnant women not concerned)
Time Frame
day 90
Title
blood pressure
Description
Dysatolic/systolic blood pressure in mmHg
Time Frame
Day 0
Title
blood pressure
Description
Dysatolic/systolic blood pressure in mmHg
Time Frame
day 10
Title
blood pressure
Description
Dysatolic/systolic blood pressure in mmHg
Time Frame
day 21
Title
blood pressure
Description
Dysatolic/systolic blood pressure in mmHg
Time Frame
day 90
Title
body temperature
Description
Body temperature in °C
Time Frame
Day 0
Title
body temperature
Description
Body temperature in °C
Time Frame
day 10
Title
body temperature
Description
Body temperature in °C
Time Frame
day 21
Title
body temperature
Description
Body temperature in °C
Time Frame
day 90
Title
clinical exam (skin)
Description
Skin mottling in terms of presence/absence
Time Frame
Day 0
Title
clinical exam (skin)
Description
Skin mottling in terms of presence/absence
Time Frame
day 10
Title
clinical exam (skin)
Description
Skin mottling in terms of presence/absence
Time Frame
day 21
Title
clinical exam (skin)
Description
Skin mottling in terms of presence/absence
Time Frame
day 90
Title
clinical exam (polypnea)
Description
polypnea in terms of presence/absence
Time Frame
Day 0
Title
clinical exam (polypnea)
Description
polypnea in terms of presence/absence
Time Frame
day 10
Title
clinical exam (polypnea)
Description
polypnea in terms of presence/absence
Time Frame
day 21
Title
clinical exam (polypnea)
Description
polypnea in terms of presence/absence
Time Frame
day 90
Title
denutrition
Description
denutrition in terms of presence/absence
Time Frame
Day 0
Title
denutrition
Description
denutrition in terms of presence/absence
Time Frame
day 10
Title
denutrition
Description
denutrition in terms of presence/absence
Time Frame
day 21
Title
denutrition
Description
denutrition in terms of presence/absence
Time Frame
day 90
Title
Antibiotic treatment
Description
Antibiotic treatment in terms of presence/absence with precision if necessary
Time Frame
Day 0
Title
Antibiotic treatment
Description
Antibiotic treatment in terms of presence/absence with precision if necessary
Time Frame
day 10
Title
Antibiotic treatment
Description
Antibiotic treatment in terms of presence/absence with precision if necessary
Time Frame
day 21
Title
Antibiotic treatment
Description
Antibiotic treatment in terms of presence/absence with precision if necessary
Time Frame
day 90
Title
Steroidal anti-inflammatory treatment
Description
Steroidal anti-inflammatory treatment in terms of presence/absence with precision if necessary
Time Frame
Day 0
Title
Steroidal anti-inflammatory treatment
Description
Steroidal anti-inflammatory treatment in terms of presence/absence with precision if necessary
Time Frame
day 10
Title
Steroidal anti-inflammatory treatment
Description
Steroidal anti-inflammatory treatment in terms of presence/absence with precision if necessary
Time Frame
day 21
Title
Steroidal anti-inflammatory treatment
Description
Steroidal anti-inflammatory treatment in terms of presence/absence with precision if necessary
Time Frame
day 90
Title
Anti-diabetic treatment
Description
Anti-diabetic treatment in terms of presence/absence with precision if necessary
Time Frame
Day 0
Title
Anti-diabetic treatment
Description
Anti-diabetic treatment in terms of presence/absence with precision if necessary
Time Frame
day 10
Title
Anti-diabetic treatment
Description
Anti-diabetic treatment in terms of presence/absence with precision if necessary
Time Frame
day 21
Title
Anti-diabetic treatment
Description
Anti-diabetic treatment in terms of presence/absence with precision if necessary
Time Frame
day 90
Title
Gastric protector treatment
Description
Gastric protector treatment in terms of presence/absence with precision if necessary
Time Frame
Day 0
Title
Gastric protector treatment
Description
Gastric protector treatment in terms of presence/absence with precision if necessary
Time Frame
day 10
Title
Gastric protector treatment
Description
Gastric protector treatment in terms of presence/absence with precision if necessary
Time Frame
day 21
Title
Gastric protector treatment
Description
Gastric protector treatment in terms of presence/absence with precision if necessary
Time Frame
day 90
Title
chills
Description
chills in terms of presence/absence
Time Frame
Day 0
Title
chills
Description
chills in terms of presence/absence
Time Frame
day 10
Title
chills
Description
chills in terms of presence/absence
Time Frame
day 21
Title
chills
Description
chills in terms of presence/absence
Time Frame
day 90
Title
Myalgia
Description
Myalgia in terms of presence/absence
Time Frame
Day 0
Title
Myalgia
Description
Myalgia in terms of presence/absence
Time Frame
day 10
Title
Myalgia
Description
Myalgia in terms of presence/absence
Time Frame
day 21
Title
Myalgia
Description
Myalgia in terms of presence/absence
Time Frame
day 90
Title
Anorexia
Description
Anorexia in terms of presence/absence
Time Frame
Day 0
Title
Anorexia
Description
Anorexia in terms of presence/absence
Time Frame
day 10
Title
Anorexia
Description
Anorexia in terms of presence/absence
Time Frame
day 21
Title
Anorexia
Description
Anorexia in terms of presence/absence
Time Frame
day 90
Title
Rhinitis
Description
Rhinitis in terms of presence/absence
Time Frame
Day 0
Title
Rhinitis
Description
Rhinitis in terms of presence/absence
Time Frame
day 10
Title
Rhinitis
Description
Rhinitis in terms of presence/absence
Time Frame
day 21
Title
Rhinitis
Description
Rhinitis in terms of presence/absence
Time Frame
day 90
Title
Confusion
Description
Confusion in terms of presence/absence
Time Frame
Day 0
Title
Confusion
Description
Confusion in terms of presence/absence
Time Frame
day 10
Title
Confusion
Description
Confusion in terms of presence/absence
Time Frame
day 21
Title
Confusion
Description
Confusion in terms of presence/absence
Time Frame
day 90
Title
Asthenia
Description
Asthenia in terms of presence/absence
Time Frame
Day 0
Title
Asthenia
Description
Asthenia in terms of presence/absence
Time Frame
day 10
Title
Asthenia
Description
Asthenia in terms of presence/absence
Time Frame
day 21
Title
Asthenia
Description
Asthenia in terms of presence/absence
Time Frame
day 90
Title
Falls at home
Description
Falls at home in terms of presence/absence
Time Frame
Day 0
Title
Falls at home
Description
Falls at home in terms of presence/absence
Time Frame
day 10
Title
Falls at home
Description
Falls at home in terms of presence/absence
Time Frame
day 21
Title
Falls at home
Description
Falls at home in terms of presence/absence
Time Frame
day 90
Title
Insomnia
Description
Insomnia in terms of presence/absence
Time Frame
Day 0
Title
Insomnia
Description
Insomnia in terms of presence/absence
Time Frame
day 10
Title
Insomnia
Description
Insomnia in terms of presence/absence
Time Frame
day 21
Title
Insomnia
Description
Insomnia in terms of presence/absence
Time Frame
day 90
Title
Angina
Description
Angina in terms of presence/absence
Time Frame
Day 0
Title
Angina
Description
Angina in terms of presence/absence
Time Frame
day 10
Title
Angina
Description
Angina in terms of presence/absence
Time Frame
day 21
Title
Angina
Description
Angina in terms of presence/absence
Time Frame
day 90
Title
Ageusia
Description
Ageusia in terms of presence/absence
Time Frame
Day 0
Title
Ageusia
Description
Ageusia in terms of presence/absence
Time Frame
day 10
Title
Ageusia
Description
Ageusia in terms of presence/absence
Time Frame
day 21
Title
Ageusia
Description
Ageusia in terms of presence/absence
Time Frame
day 90
Title
Respiratory complaints
Description
Respiratory complaints in term of SRIpr score from 0 to 100
Time Frame
Day 0
Title
Respiratory complaints
Description
Respiratory complaints in term of SRIpr score from 0 to 100
Time Frame
day 2
Title
Respiratory complaints
Description
Respiratory complaints in term of SRIpr score from 0 to 100
Time Frame
day 4
Title
Respiratory complaints
Description
Respiratory complaints in term of SRIpr score from 0 to 100
Time Frame
day 6
Title
Respiratory complaints
Description
Respiratory complaints in term of SRIpr score from 0 to 100
Time Frame
day 8
Title
Respiratory complaints
Description
Respiratory complaints in term of SRIpr score from 0 to 100
Time Frame
day 10
Title
Respiratory complaints
Description
Respiratory complaints in term of SRIpr score from 0 to 100
Time Frame
day 21
Title
Respiratory complaints
Description
Respiratory complaints in term of SRIpr score from 0 to 100
Time Frame
day 90
Title
transmission rate
Description
Rate of viral transmission determine by bioinformatic and statistical analyzes in %
Time Frame
Day 0
Title
transmission rate
Description
Rate of viral transmission determine by bioinformatic and statistical analyzes in %
Time Frame
day 10
Title
transmission rate
Description
Rate of viral transmission determine by bioinformatic and statistical analyzes in %
Time Frame
day 21
Title
prolonged viral shedding
Description
Prolonged viral shedding evaluate by RT-PCR (CT value or log10 copies per mL)
Time Frame
between day 0 and day 21
10. Eligibility
Sex
All
Accepts Healthy Volunteers
Accepts Healthy Volunteers
Eligibility Criteria
Inclusion Criteria:
Child or adult, no age limit
Able to give informed consent to participate in research
If a minor participant: consent of the legal representatives
If confirmed case COVID-19 (symptomatic or asymptomatic): laboratory result confirming infection with SARS-CoV-2 by RT-PCR or by serology
If contact case: people identified as a risk contact according to the criteria of the "Amélie.fr" health insurance
Exclusion Criteria:
Subjects under tutorship, curatorship, deprived of liberty, safeguard of justice
Refusal of the child
Refusal of participation
Central Contact Person:
First Name & Middle Initial & Last Name or Official Title & Degree
Lise LACLAUTRE
Phone
+33473754963
Email
promo_interne_drci@chu-clermontferrand.fr
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Céclie Henquell
Organizational Affiliation
University Hospital, Clermont-Ferrand
Official's Role
Principal Investigator
Facility Information:
Facility Name
CHU de Clermont-Ferrand
City
Clermont-Ferrand
ZIP/Postal Code
63000
Country
France
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Lise Laclautre
Phone
+33473754963
Email
promo_interne_drci@chu-clermontferrand.fr
First Name & Middle Initial & Last Name & Degree
Cécile Henquell
First Name & Middle Initial & Last Name & Degree
Olivier Lesens
First Name & Middle Initial & Last Name & Degree
Magali Vidal
First Name & Middle Initial & Last Name & Degree
Etienne Merlin
First Name & Middle Initial & Last Name & Degree
Marc Berger
12. IPD Sharing Statement
Learn more about this trial
Relationship Between Biological Profiles and Clinical Evolutions Within the Same Cluster COVID-19 (COVIDCOLLECT)
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