Efficacy of Probiotics in Reducing Duration and Symptoms of COVID-19 (PROVID-19)
COVID-19
About this trial
This is an interventional treatment trial for COVID-19 focused on measuring covid, sars-cov-2, coronavirus
Eligibility Criteria
Inclusion Criteria:
- First positive test for COVID-19 in the last 5 days;
- Having symptoms of the COVID-19 at enrollment;
- Self-caring at home;
- Living in Quebec for the next 60 days;
- Able to take medication alone;
- With access to a phone or to the Internet;
- Able to give informed consent.
Exclusion Criteria:
- Taking probiotic supplements at enrollment;
- Taking antibiotics for a reason other than COVID-19 at enrollment;
- Allergies to soy, lactose, yeast, maltodextrin, vitamin C, potato starch, magnesium stearate, hypromellose or titanium dioxide;
- Has a chronically weakened immune system (AIDS, lymphoma, chemo-radio- corticosteroid therapy, immunosuppressive pathology);
- Was treated with chemo-radio-corticosteroid therapy in the last 6 months;
- Has active cancer;
- Taking immunosuppressive drugs (e.g. anti-rejection treatment after organ transplant);
- Already participating in another clinical trial;
- Is pregnant, expects to become pregnant in the next few months or is breastfeeding;
- Has any other condition that would prevent safe participation in the study.
Sites / Locations
- CIUSSS de L'Estrie-CHUS Hospital
Arms of the Study
Arm 1
Arm 2
Experimental
Placebo Comparator
Probiotics
Placebo
Two probiotic strains will constitute the experimental arm (Probiotics). Patients will take two capsules a day (one closed capsule to swallow and one open capsule mixed with maple syrup) from Day 1 to Day 10 and one closed capsule to swallow from Day 11 to Day 25.They will stop the treatment if they are admitted to the hospital. The treatment will last a maximum of 25 days.
Potato starch and magnesium stearate will constitute the comparator arm (Placebo). Patients will take two capsules a day (one closed capsule to swallow and one open capsule mixed with maple syrup) from Day 1 to Day 10 and one closed capsule to swallow from Day 11 to Day 25.They will stop the treatment if they are admitted to the hospital. The treatment will last a maximum of 25 days.