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Spaced Retrieval as Treatment for Aphasia

Primary Purpose

Aphasia, Acquired, Aphasia Primary Progressive

Status

Completed

Phase

Not Applicable

Locations

Canada

Study Type

Interventional

Intervention

Spaced Retrieval Practice

About this trial

This is an interventional treatment trial for Aphasia, Acquired focused on measuring Adaptive Spaced-Retrieval, Aphasia, Anomia, Anki

Eligibility Criteria

undefined - undefined (Child, Adult, Older Adult)All SexesDoes not accept healthy volunteers

Inclusion Criteria:

presence of a post-stroke word finding deficit (i.e. aphasia), or primary progressive aphasia.
ability to evaluate the correctness of one's own responses when subsequently provided the with the correct answer

Exclusion Criteria:

diagnosis of a neurological disorder other than post-stroke or primary progressive aphasia
inability to evaluate the correctness of ones responses when subsequently provided with the correct answer

Sites / Locations

Baycrest Health Sciences

Arms of the Study

Arm 1

Arm Type

Experimental

Arm Label

Spaced Repetition

Arm Description

Two weeks (10 sessions) of online picture-naming training with 60 words.

Outcomes

Primary Outcome Measures

Change in Picture Naming performance across conditions

Word retention assessed after treatment

Secondary Outcome Measures

Full Information

NCT ID

NCT04623125

First Posted

October 29, 2020

Last Updated

March 27, 2023

Sponsor

Rotman Research Institute at Baycrest

Collaborators

Heart and Stroke Foundation of Canada

1. Study Identification

Unique Protocol Identification Number

NCT04623125

Brief Title

Spaced Retrieval as Treatment for Aphasia

Official Title

Spaced Retrieval as Treatment for Aphasia: Does Adaptive Spacing Enhance Picture Naming Performance?

Study Type

Interventional

2. Study Status

Record Verification Date

March 2023

Overall Recruitment Status

Completed

Study Start Date

October 1, 2020 (Actual)

Primary Completion Date

January 1, 2022 (Actual)

Study Completion Date

January 1, 2022 (Actual)

3. Sponsor/Collaborators

Responsible Party, by Official Title

Principal Investigator

Name of the Sponsor

Rotman Research Institute at Baycrest

Collaborators

Heart and Stroke Foundation of Canada

4. Oversight

Studies a U.S. FDA-regulated Drug Product

Studies a U.S. FDA-regulated Device Product

Data Monitoring Committee

5. Study Description

Brief Summary

Spaced Repetition training has been found to be more effective than massed repetition for individuals with aphasia. This study seeks to examine the relative efficiency of three kinds of spacing for picture-naming training: traditional random presentation, non-adaptive spaced repetition, and adaptive spaced repetition.

Detailed Description

Participants undergo a screening evaluation including the Quick Aphasia Battery (administered via teleconferencing software), and a preliminary picture naming test of approximately 300 pictures, used to select individual items for treatment. Participants then undertake online picture naming training for 30 minutes a day, over two weeks. Pictures are repeated according to three different schedules to be compared: random presentation, non-adaptive spaced repetition, and adaptive spaced repetition. We compare the number of pictures successfully learned and the verbal reaction time for the pictures assigned to the three conditions.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study

Aphasia, Acquired, Aphasia Primary Progressive

Keywords

Adaptive Spaced-Retrieval, Aphasia, Anomia, Anki

7. Study Design

Primary Purpose

Treatment

Study Phase

Not Applicable

Interventional Study Model

Single Group Assignment

Masking

None (Open Label)

Allocation

N/A

Enrollment

21 (Actual)

8. Arms, Groups, and Interventions

Arm Title

Spaced Repetition

Arm Type

Experimental

Arm Description

Two weeks (10 sessions) of online picture-naming training with 60 words.

Intervention Type

Behavioral

Intervention Name(s)

Spaced Retrieval Practice

Intervention Description

Online picture-naming training with 60 words which the participant experiences word-retrieval difficulties. Cards are shuffled arranged by the computerized training program.

Primary Outcome Measure Information:

Title

Change in Picture Naming performance across conditions

Description

Word retention assessed after treatment

Time Frame

Change from baseline to post-intervention immediately after two weeks of daily sessions, and one month followup.

10. Eligibility

Sex

All

Accepts Healthy Volunteers

Eligibility Criteria

Inclusion Criteria: presence of a post-stroke word finding deficit (i.e. aphasia), or primary progressive aphasia. ability to evaluate the correctness of one's own responses when subsequently provided the with the correct answer Exclusion Criteria: diagnosis of a neurological disorder other than post-stroke or primary progressive aphasia inability to evaluate the correctness of ones responses when subsequently provided with the correct answer

Facility Information:

Facility Name

Baycrest Health Sciences

City

Toronto

State/Province

Ontario

ZIP/Postal Code

M6A 2E1

Country

Canada

12. IPD Sharing Statement

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Spaced Retrieval as Treatment for Aphasia

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