Comparing Local Anesthesia With and Without iPACK Block
Osteo Arthritis Knee, Analgesia, Pain, Postoperative
About this trial
This is an interventional supportive care trial for Osteo Arthritis Knee
Eligibility Criteria
Inclusion Criteria:
- Patients scheduled for elective unilateral TKA
- Planned for regional anesthesia for the procedure
- Age >=18
Exclusion criteria:
- Contraindications to regional anesthesia or peripheral nerve blocks
- Allergy to local anesthetics or any of the study medications
- Severe hepatic or renal insufficiency
- Chronic opioid consumption
- Patient with difficulty comprehending visual analogue scale pain scores
- Pre-existing lower extremity neurologic abnormalities
- Patients classified as American Society of Anesthesiologists score 3 or 4
- Language/communication barrier
Sites / Locations
- University of Calgary/AB Hip and Knee ClinicRecruiting
Arms of the Study
Arm 1
Arm 2
Placebo Comparator
Active Comparator
Sham iPACK block
Real IPACK block.
This groups will receive the adductor canal block with the local anesthetic (15 mL of 0.25% bupivacaine + 2.5 mcg/mL epinephrine + 50 mcg/mL preservative-free dexamethasone) and local infiltration of analgesia+ sham iPACK block with 20 mL of normal saline.
This groups will receive the adductor canal block with the local anesthetic (15 mL of 0.25% bupivacaine + 2.5 mcg/mL epinephrine + 50 mcg/mL preservative-free dexamethasone) and local infiltration of analgesia + real iPACK block with 20 mL of 0.25% bupivacaine, 2.5mcg/mL epinephrine, and 50mcg/mL preservative-free dexamethasone