Necessity of Preoperative Empirical Antibiotic Use in Acute Cholecystitis
Cholecystitis, Acute
About this trial
This is an interventional treatment trial for Cholecystitis, Acute focused on measuring empirical antibiotics, postoperative complication
Eligibility Criteria
Inclusion Criteria:
- among patients with mild acute cholecystitis (grade I by Tokyo guidelines) or moderate acute cholecystitis without evidence of gallbladder perforation(grade II)
- cholecystitis with a thickness of 4 mm or more on gallbladder in preoperative imaging
- Gallbladder with surrounding organs due to gallbladder inflammation
- Patients over 19 years of age, under 70 years of age
Exclusion Criteria:
- patients with elective gallbladder surgery (chronic cholecystitis)
- gallbladder disease not inflammatory disease (GB cancer, GB polyp)
- pregnant women, patients under 18 years of age, over 70 years of age
- patients with simultaneous surgery due to other organ diseases
- immunosuppressed patients; liver transplant patients, kidney transplant patients, acquired immunodeficiency syndrome patients
- patients with hemorrhagic tendency, or with hematologic diseases
- Patients who underwent percutaneous cholecystectomy (PTGBD)
Sites / Locations
- Department of HBP Surgery, Seoul St. Mary's hospital
Arms of the Study
Arm 1
Arm 2
Experimental
Experimental
The experimental group in acute cholecystitis
The controled group in acute cholecystitis
inclusion criteria among patients with mild acute cholecystitis (grade I by Tokyo guidelines) or moderate acute cholecystitis without evidence of gallbladder perforation(grade II) cholecystitis with a thickness of 4 mm or more on gallbladder in preoperative imaging Gallbladder with surrounding organs due to gallbladder inflammation Patients over 19 years of age normal saline (Isotonic Sodium Chloride Injection Daihan(50mL/bag)) was used before surgery.
among patients with mild acute cholecystitis (grade I by Tokyo guidelines) or moderate acute cholecystitis without evidence of gallbladder perforation(grade II) cholecystitis with a thickness of 4 mm or more on gallbladder in preoperative imaging Gallbladder with surrounding organs due to gallbladder inflammation Patients over 19 years of age First-generation cephalosporin (Cefazolin inj., 1g, Cefazolin sodium, Chong-geun-dang pharm.co.) was used before surgery.