Effects of Multilac Baby on Fecal Calprotectin Levels of Colicky Babies
Infantile Colic
About this trial
This is an interventional treatment trial for Infantile Colic
Eligibility Criteria
Inclusion Criteria:
- diagnosed for infantile colic according to Wessel's criteria
Exclusion Criteria:
- previous treatment with probiotic or synbiotic
- previous treatment with antibiotics
Sites / Locations
- GP Clinic "Panaceum"
- GP Clinic "Pro Familia"
Arms of the Study
Arm 1
Arm 2
Active Comparator
Experimental
Simethicone Solution
Multilac Baby
Treatment with simethicone (Espumisan®, 100 mg/ml, Berlin-Chemie / Menarini Polska Sp z o.o., Warsaw, Poland) for four weeks. Simethicone was administered 3-6 times per day with each treatment comprising 6 drops of the 100 mg/ml emulsion.
Treatment with one stick pack of the multi-strain synbiotic (Multilac® Baby, Vivatrex GmbH, Aachen, Germany) per day for four weeks. Each stick pack of Multilac® Baby contains a total of 10^9 colony forming units (CFU) with equal CFU amounts of the following probiotic bacteria: L. acidophilus LA-14, L. casei R0215; L. paracasei Lpc-3; L. plantarum Lp-115; L. rhamnosus GG, L. salivarius Ls-33, B. lactis Bl-04, B. bifidum R0071, B. longum R0175 and 1.43 g of the prebiotic fructooligosaccharides.