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Tisotumab Vedotin vs Chemotherapy in Recurrent or Metastatic Cervical Cancer (innovaTV 301)

Primary Purpose

Cervical Cancer

Status
Recruiting
Phase
Phase 3
Locations
International
Study Type
Interventional
Intervention
tisotumab vedotin
topotecan
vinorelbine
gemcitabine
irinotecan
pemetrexed
Sponsored by
Seagen Inc.
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional treatment trial for Cervical Cancer focused on measuring Seattle Genetics

Eligibility Criteria

18 Years - undefined (Adult, Older Adult)FemaleDoes not accept healthy volunteers

Inclusion Criteria

  • Has recurrent or metastatic cervical cancer with squamous cell, adenocarcinoma, or adenosquamous histology, and:

  • Has experienced disease progression during or after treatment with a standard of care systemic chemotherapy doublet, or platinum-based therapy (if eligible), defined as either:

    • paclitaxel + cisplatin + bevacizumab + anti-PD-(L)1 agent, or
    • paclitaxel + carboplatin + bevacizumab + anti-PD-(L)1 agent, or
    • paclitaxel + topotecan/nogitecan + bevacizumab + anti-PD-(L)1 agent
  • Note: In cases where bevacizumab and/or anti-PD-(L)1 agent is not a standard of care therapy or the participant was ineligible for such treatment according to local standards, prior treatment with bevacizumab and/or anti-PD-(L)1 agent is not required.
  • Has received 1 or 2 prior systemic therapy regimens for recurrent and/or metastatic cervical cancer. Chemotherapy administered in the adjuvant or neoadjuvant setting, or in combination with radiation therapy, should not be counted as a systemic therapy regimen. Single agent therapy with an anti-PD(L)1 agent for r/mCC cancer should be counted.
  • Measurable disease according to RECIST v1.1 as assessed by the investigator.
  • Has ECOG performance status of 0 or 1 prior to randomization.
  • Has life expectancy of at least 3 months.

Exclusion Criteria

  • Has primary neuroendocrine, lymphoid, sarcomatoid, or other histologies not mentioned as part of the inclusion criteria above.
  • Has clinically significant bleeding issues or risks. This includes known past or current coagulation defects leading to an increased risk of bleeding; diffuse alveolar hemorrhage from vasculitis; known bleeding diathesis; ongoing major bleeding; trauma with increased risk of life-threatening bleeding or history of severe head trauma or intracranial surgery within 8 weeks of trial entry.
  • Has any history of intracerebral arteriovenous malformation, cerebral aneurysm, or stroke (transient ischemic attack >1 month prior to screening is allowed).
  • Active ocular surface disease or a history of cicatricial conjunctivitis or inflammatory conditions that predispose to cicatrizing conjunctivitis (e.g. Wagner syndrome, atopic keratoconjunctivitis, autoimmune disease affecting the eyes), ocular Stevens-Johnson syndrome or toxic epidermal necrolysis, mucus pemphigoid, and participants with penetrating ocular transplants. Cataracts alone is not an exclusion criterion.
  • Major surgery within 4 weeks or minor surgery within 7 days prior to the first study treatment administration.
  • Peripheral neuropathy ≥grade 2.
  • Any prior treatment with monomethyl auristatin E (MMAE)-containing drugs.

There are additional inclusion and exclusion criteria. The study center will determine if criteria for participation are met.

Sites / Locations

  • University of Alabama at Birmingham
  • Arizona Oncology Associates, PC - HAL
  • Arizona Oncology Associates, PC - HOPE
  • University of California Irvine Medical Center
  • Olive View - UCLA Medical Center
  • Yale Cancer Center
  • Broward Health Medical Center
  • Augusta University
  • Northwestern Memorial Hospital
  • Gynecological Cancer Institute of Chicago, LLC
  • Norton Cancer Institute
  • Willis-Knighton Physician Network/Gynecologic Oncology Associates
  • Maryland Oncology Hematology, P.A.
  • Minnesota Oncology Hematology P.A.
  • St. Dominic - Jackson Memorial Hospital
  • Washington University in St Louis
  • Holy Name Medical Center
  • Weill Cornell Medicine
  • Weill Cornell Medicine
  • New York University (NYU) Cancer Institute
  • UNC Lineberger Comprehensive Cancer Center / University of North Carolina
  • Cleveland Clinic Fairview Hospital
  • Cleveland Clinic, The
  • Ohio State University Clinical Trials Management Office
  • Kettering Health
  • Cleveland Clinic Hillcrest Hospital
  • Oncology Associates of Oregon
  • Northwest Cancer Specialists, P.C.
  • Texas Oncology - Austin Central
  • Texas Oncology - Fort Worth 12th Avenue
  • Texas Oncology - The Woodlands
  • Texas Oncology - Tyler
  • University of Virginia
  • Virginia Oncology Associates
  • Virginia Commonwealth University Medical Center
  • Carbone Cancer Center / University of Wisconsin
  • Instituto Oncologico de Cordoba
  • Fundacion Cenit
  • Instituto Alexander Fleming
  • Sanatorio de la Mujer
  • LKH- Universitat Klinikum Graz
  • AKH - Medizinische Universitat Wien
  • Institut Jules Bordet
  • ZNA Middelheim
  • Cliniques Universitaires Saint Luc
  • Universitair Ziekenhuis Gent
  • UZ Leuven campus Gasthuisberg
  • CHU de Liege
  • CHU UCL Namur-Site de Saint Elisabeth
  • Grand Hopital de Charleroi
  • Hospital Mãe de Deus
  • Erasto Gaertner Hospital
  • Instituto Brasileiro de Controle do Cancer
  • Hospital de Caridade de Ijuí
  • Centro de PesquisaemOncologia - HSL-PUCRS
  • Brazilian National Cancer Institute
  • Fundação NAtonio Prudente (AC Camargo Cancer Center)
  • Hospital Beneficencia Portuguesa
  • University of Alberta / Cross Cancer Institute
  • British Columbia Cancer Agency - Vancouver Centre
  • Sunnybrook Health Sciences Centre
  • University Health Network, Princess Margaret Hospital
  • Centre Hospitalier de l'Universite de Montreal
  • Saskatoon Cancer Centre
  • Cancer Hospital Chinese Academy of Medical SciencesRecruiting
  • Beijing Obstetrics and Gynecology HospitalRecruiting
  • Peking University People's HospitalRecruiting
  • Jilin University - First Affiliated Hospital - Cancer CenterRecruiting
  • The Third Xiangya Hospital of Central South UniversityRecruiting
  • Chongqing Cancer HospitalRecruiting
  • Shandong Cancer HospitalRecruiting
  • Shanghai First People's HospitalRecruiting
  • The Second Hospital of Shanxi Medical UniversityRecruiting
  • The Affiliated Cancer Hospital of XinJiang Medical UniversityRecruiting
  • Union Hospital affiliated to Tongji Medical College of Huazhong University of Science and TechnologyRecruiting
  • Hubei Cancer HospitalRecruiting
  • Shaanxi Provincial People's HospitalRecruiting
  • Fakultni nemocnice Brno
  • Fakultni Nemocnice Olomouc (Fnol) - Onkologicka Klinika
  • General University Hospital Prague
  • Hospital Na Bulovce
  • Rigshospitalet
  • University of Turku
  • Kuopio University Hospital
  • Tampere University Hospital
  • Centre Hospitalier Regional et Universitaire de Besancon - Hopital Jean-Minjoz
  • Centre de Lutte Contre le Cancer (CLCC) - Institut Bergonie
  • Centre de Lutte contre le Cancer - François Baclesse
  • CARIO - Centre Armoricain De Radiothérapie, D'imagerie Médicale Et D'oncologie
  • Institute Cancer De Lorraine (ICL) - Alexis Vautrin
  • Hopital Prive du Confluent
  • Groupe Hospitalier Diaconesses Croix Saint-Simon - Site Avron (Hopital de la Croix Saint-Simon)
  • Institut de cancerologie Strasbourg Europe
  • Institut Claudius Regaud IUCT-O
  • Institut Gustave Roussy
  • Kliniken Essen-Mitte
  • Universitaetsklinikum Essen
  • Universitaetsklinikum Hamburg-Eppendorf (UKE)
  • University Hospital LMU Munich
  • National Institute of Oncology Hungary
  • Medical and Health Science Centre Debrecen Institution of Internal Medicine
  • Bacs-Kiskun Varmegyei Oktatokorhaz
  • University Hospital Waterford
  • Azienda Ospedaliera per l'Emergenza
  • Ospedale San Raffaele
  • Fondazione Policlinico Universitario Agostino
  • Hospital San Bortolo
  • IRCCS Istituto Romagnolo per lo Studio dei Tumori Dino Amadori- IRST S.r.l
  • National Cancer Center Hospital
  • Kurume University Hospital
  • Gunma University Hospital
  • Saitama Cancer Center
  • Kagoshima University Hospital
  • Kagoshima City Hospital
  • National Cancer Center Hospital East
  • The Jikei University Kashiwa Hospital
  • NHO Shikoku Cancer Center
  • Aichi Cancer Center
  • University of the Ryukyus Hospital
  • Okayama University Hospital
  • Kindai University Hospital
  • Osaka International Cancer Institute
  • National Hospital Organization Hokkaido Cancer Center
  • Hokkaido University Hospital
  • Shizuoka Cancer Center
  • The Cancer Institute Hospital of JFCR
  • Keio University Hospital
  • Kanagawa Cancer Center
  • Hyogo Cancer Center
  • Ehime University Hospital
  • National Hospital Organization Kure Medical Center and Chugoku Cancer Center
  • Nippon Medical School Musashi Kosugi Hospital
  • Niigata Cancer Center Hospital
  • Iwate Medical University Hospital
  • Jikei University Hospital
  • Yokohama City University Hospital
  • Keimyung University Dongsan Medical Center
  • National Cancer Center
  • Seoul National University Bundang Hospital
  • CHA Bundang Medical Center
  • Korea Cancer Center Hospital
  • Seoul National University Hospital
  • Soon Chun Hyang University Hospital Seoul
  • Asan Medical Center
  • Samsung Medical Center
  • Seoul Saint Mary's Hospital
  • Ewha Womans University Mokdong Hospital
  • Severance Hospital, Yonsei University Health System
  • Inje University Busan-Paik Hospital
  • Sungkyunkwan University of Medicine - Samsung Changwon Hospital
  • Gangnam Severance Hospital
  • Oncologico Potosino
  • Amsterdam UMC, Locatie AMC
  • Maastricht University Medical Center
  • Radboud University Medical Center
  • Erasmus Medisch Centrum Daniel Den Hoed
  • Universitair Medisch Centrum Utrecht
  • Oslo University Hospital, Radiumhospitalet
  • Trondheim University Hospital, Trondheim
  • Hospital Maria Auxiliadora
  • Białostockie Centrum Onkologii
  • National University Cancer Institute, Singapore
  • National Cancer Centre Singapore
  • Hospital Universitari Vall d'Hebron
  • Hospital Clinic de Barcelona
  • Hospital Universitario Reina Sofia
  • Clinica Universidad de Navarra
  • Hospital Universitario 12 de Octubre
  • Hospital Universitario La Paz
  • Clinica Universidad de Navarra
  • Hospital Clinico Universitario de Valencia
  • Linkoping University Hospital
  • Skanes University Hospital - Universitetssjukhus
  • Uppsala University Hospital (Akademiska Sjukhuset)
  • Mackay Memorial Hospital
  • Chang Gung Memorial Hospital - Linkou
  • Taipei Veterans General Hospital
  • Cambridge University Hospitals NHS Foundation Trust
  • Royal Devon and Exeter NHS Foundation Trust
  • The Royal Marsden Hospital
  • The Christie NHS Foundation Trust
  • The Royal Marsden Hospital (Surrey)
  • The Beatson West of Scotland Cancer Centre

Arms of the Study

Arm 1

Arm 2

Arm Type

Experimental

Active Comparator

Arm Label

Tisotumab vedotin

Chemotherapy

Arm Description

Tisotumab vedotin monotherapy

Investigator's choice of one chemotherapy treatment (topotecan, vinorelbine, gemcitabine, irinotecan, or pemetrexed)

Outcomes

Primary Outcome Measures

Overall survival (OS)
OS is defined as the time from the date of randomization to the date of death due to any cause.

Secondary Outcome Measures

Progression-free survival (PFS) based on Response Evaluation Criteria in Solid Tumors (RECIST) v1.1 as assessed by the investigator
PFS per investigator is defined as the time from the date of randomization to the first documentation of disease progression per RECIST v.1.1 by the investigator, or to date of death due to any cause, whichever occurs earlier.
Confirmed objective response rate (ORR) based on RECIST v1.1 as assessed by the investigator
Confirmed objective response rate is defined as the proportion of participants with a confirmed complete response (CR) or partial response (PR) per RECIST v.1.1.
Time-to-response (TTR) as assessed by the investigator
TTR is defined as the time from the date of randomization to the date of first confirmed objective response (CR or PR that is subsequently confirmed). Only participants with confirmed CR or PR will be included in the analysis.
Duration of response (DOR) as assessed by the investigator
DOR is defined as the time from the date of first confirmed objective response (CR or PR that is subsequently confirmed) to the date of first documented PD per RECIST v1.1 or death from any cause, whichever occurs first. Only participants with confirmed CR or PR will be included in the analysis.
Incidence of adverse events (AEs)
Analyses of AEs will be summarized descriptively
Health-related quality of life as assessed by EQ-5D-5L index
EQ-5D-5L is a standardized instrument developed by the EuroQol Group as a measure of HRQOL that can be used in a wide range of health conditions and treatments. The EQ-5D-5L consists of a descriptive system and the EQ VAS. The descriptive system comprises 5 dimensions: mobility, self-care, usual activities, pain/discomfort, and anxiety/depression.
Health-related quality of life as assessed by EQ-5D visual analog scale (VAS)
EQ-5D-5L is a standardized instrument developed by the EuroQol Group as a measure of HRQOL that can be used in a wide range of health conditions and treatments. The EQ-5D-5L consists of a descriptive system and the EQ VAS. The EQ VAS records the participant's self-rated health on a vertical VAS. This can be used as a quantitative measure of health outcome that reflects the participant's own judgment.
Health-related quality of life as assessed by EORTC-QLQ-C30
The QLQ-C30 is a validated questionnaire developed by the European Organization for Research and Treatment of Cancer (EORTC) to assess the quality of life of participants with cancer in multicultural clinical research settings.
Health-related quality of life as assessed by EORTC-QLQ-CX24
The EORTC-QLQ-CX24 is a validated questionnaire developed by the EORTC to assess the quality of life in patients who are treated for cervical cancer both in clinical studies and in clinical practice.

Full Information

First Posted
January 4, 2021
Last Updated
October 23, 2023
Sponsor
Seagen Inc.
Collaborators
Genmab
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1. Study Identification

Unique Protocol Identification Number
NCT04697628
Brief Title
Tisotumab Vedotin vs Chemotherapy in Recurrent or Metastatic Cervical Cancer
Acronym
innovaTV 301
Official Title
A Randomized, Open-Label, Phase 3 Trial of Tisotumab Vedotin vs Investigator's Choice Chemotherapy in Second- or Third-Line Recurrent or Metastatic Cervical Cancer
Study Type
Interventional

2. Study Status

Record Verification Date
October 2023
Overall Recruitment Status
Recruiting
Study Start Date
February 22, 2021 (Actual)
Primary Completion Date
July 24, 2023 (Actual)
Study Completion Date
February 28, 2028 (Anticipated)

3. Sponsor/Collaborators

Responsible Party, by Official Title
Sponsor
Name of the Sponsor
Seagen Inc.
Collaborators
Genmab

4. Oversight

Studies a U.S. FDA-regulated Drug Product
Yes
Studies a U.S. FDA-regulated Device Product
No
Data Monitoring Committee
Yes

5. Study Description

Brief Summary
This trial is being done to find out whether tisotumab vedotin works better than chemotherapy to treat cervical cancer. People in this study have cervical cancer that has spread to other parts of the body (metastatic) or has come back after being treated (recurrent). Participants in this trial will be randomly assigned to one of two groups. One group will be treated with tisotumab vedotin. Participants in the other group will get one of five different chemotherapy drugs (topotecan, vinorelbine, gemcitabine, pemetrexed, or irinotecan). Participants and their doctors will know which group they are in. Participants in the chemotherapy group will decide with their study doctor which drug they will take.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Cervical Cancer
Keywords
Seattle Genetics

7. Study Design

Primary Purpose
Treatment
Study Phase
Phase 3
Interventional Study Model
Parallel Assignment
Masking
None (Open Label)
Allocation
Randomized
Enrollment
556 (Anticipated)

8. Arms, Groups, and Interventions

Arm Title
Tisotumab vedotin
Arm Type
Experimental
Arm Description
Tisotumab vedotin monotherapy
Arm Title
Chemotherapy
Arm Type
Active Comparator
Arm Description
Investigator's choice of one chemotherapy treatment (topotecan, vinorelbine, gemcitabine, irinotecan, or pemetrexed)
Intervention Type
Drug
Intervention Name(s)
tisotumab vedotin
Other Intervention Name(s)
TIVDAK
Intervention Description
2.0 mg/kg every 3 weeks (Q3W)
Intervention Type
Drug
Intervention Name(s)
topotecan
Intervention Description
1 or 1.25 mg/m2 intravenous (IV) on Days 1 to 5, every 21 days
Intervention Type
Drug
Intervention Name(s)
vinorelbine
Intervention Description
30 mg/m2 IV on Days 1 and 8, every 21 days
Intervention Type
Drug
Intervention Name(s)
gemcitabine
Intervention Description
1000 mg/m2 IV on Days 1 and 8, every 21 days
Intervention Type
Drug
Intervention Name(s)
irinotecan
Intervention Description
100 or 125 mg/m2 IV weekly for 28 days, every 42 days
Intervention Type
Drug
Intervention Name(s)
pemetrexed
Intervention Description
500 mg/m2 IV on Day 1, every 21 days
Primary Outcome Measure Information:
Title
Overall survival (OS)
Description
OS is defined as the time from the date of randomization to the date of death due to any cause.
Time Frame
Up to approximately 2 years
Secondary Outcome Measure Information:
Title
Progression-free survival (PFS) based on Response Evaluation Criteria in Solid Tumors (RECIST) v1.1 as assessed by the investigator
Description
PFS per investigator is defined as the time from the date of randomization to the first documentation of disease progression per RECIST v.1.1 by the investigator, or to date of death due to any cause, whichever occurs earlier.
Time Frame
Up to approximately 1 year
Title
Confirmed objective response rate (ORR) based on RECIST v1.1 as assessed by the investigator
Description
Confirmed objective response rate is defined as the proportion of participants with a confirmed complete response (CR) or partial response (PR) per RECIST v.1.1.
Time Frame
Up to approximately 6 months
Title
Time-to-response (TTR) as assessed by the investigator
Description
TTR is defined as the time from the date of randomization to the date of first confirmed objective response (CR or PR that is subsequently confirmed). Only participants with confirmed CR or PR will be included in the analysis.
Time Frame
Up to approximately 6 months
Title
Duration of response (DOR) as assessed by the investigator
Description
DOR is defined as the time from the date of first confirmed objective response (CR or PR that is subsequently confirmed) to the date of first documented PD per RECIST v1.1 or death from any cause, whichever occurs first. Only participants with confirmed CR or PR will be included in the analysis.
Time Frame
Up to approximately 1 year
Title
Incidence of adverse events (AEs)
Description
Analyses of AEs will be summarized descriptively
Time Frame
Up to approximately 2 years
Title
Health-related quality of life as assessed by EQ-5D-5L index
Description
EQ-5D-5L is a standardized instrument developed by the EuroQol Group as a measure of HRQOL that can be used in a wide range of health conditions and treatments. The EQ-5D-5L consists of a descriptive system and the EQ VAS. The descriptive system comprises 5 dimensions: mobility, self-care, usual activities, pain/discomfort, and anxiety/depression.
Time Frame
Up to approximately 2 years
Title
Health-related quality of life as assessed by EQ-5D visual analog scale (VAS)
Description
EQ-5D-5L is a standardized instrument developed by the EuroQol Group as a measure of HRQOL that can be used in a wide range of health conditions and treatments. The EQ-5D-5L consists of a descriptive system and the EQ VAS. The EQ VAS records the participant's self-rated health on a vertical VAS. This can be used as a quantitative measure of health outcome that reflects the participant's own judgment.
Time Frame
Up to approximately 2 years
Title
Health-related quality of life as assessed by EORTC-QLQ-C30
Description
The QLQ-C30 is a validated questionnaire developed by the European Organization for Research and Treatment of Cancer (EORTC) to assess the quality of life of participants with cancer in multicultural clinical research settings.
Time Frame
Up to approximately 6 months
Title
Health-related quality of life as assessed by EORTC-QLQ-CX24
Description
The EORTC-QLQ-CX24 is a validated questionnaire developed by the EORTC to assess the quality of life in patients who are treated for cervical cancer both in clinical studies and in clinical practice.
Time Frame
Up to approximately 6 months

10. Eligibility

Sex
Female
Minimum Age & Unit of Time
18 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria Has recurrent or metastatic cervical cancer with squamous cell, adenocarcinoma, or adenosquamous histology, and: Has experienced disease progression during or after treatment with a standard of care systemic chemotherapy doublet, or platinum-based therapy (if eligible), defined as either: paclitaxel + cisplatin + bevacizumab + anti-PD-(L)1 agent, or paclitaxel + carboplatin + bevacizumab + anti-PD-(L)1 agent, or paclitaxel + topotecan/nogitecan + bevacizumab + anti-PD-(L)1 agent Note: In cases where bevacizumab and/or anti-PD-(L)1 agent is not a standard of care therapy or the participant was ineligible for such treatment according to local standards, prior treatment with bevacizumab and/or anti-PD-(L)1 agent is not required. Has received 1 or 2 prior systemic therapy regimens for recurrent and/or metastatic cervical cancer. Chemotherapy administered in the adjuvant or neoadjuvant setting, or in combination with radiation therapy, should not be counted as a systemic therapy regimen. Single agent therapy with an anti-PD(L)1 agent for r/mCC cancer should be counted. Measurable disease according to RECIST v1.1 as assessed by the investigator. Has ECOG performance status of 0 or 1 prior to randomization. Has life expectancy of at least 3 months. Exclusion Criteria Has primary neuroendocrine, lymphoid, sarcomatoid, or other histologies not mentioned as part of the inclusion criteria above. Has clinically significant bleeding issues or risks. This includes known past or current coagulation defects leading to an increased risk of bleeding; diffuse alveolar hemorrhage from vasculitis; known bleeding diathesis; ongoing major bleeding; trauma with increased risk of life-threatening bleeding or history of severe head trauma or intracranial surgery within 8 weeks of trial entry. Has any history of intracerebral arteriovenous malformation, cerebral aneurysm, or stroke (transient ischemic attack >1 month prior to screening is allowed). Active ocular surface disease or a history of cicatricial conjunctivitis or inflammatory conditions that predispose to cicatrizing conjunctivitis (e.g. Wagner syndrome, atopic keratoconjunctivitis, autoimmune disease affecting the eyes), ocular Stevens-Johnson syndrome or toxic epidermal necrolysis, mucus pemphigoid, and participants with penetrating ocular transplants. Cataracts alone is not an exclusion criterion. Major surgery within 4 weeks or minor surgery within 7 days prior to the first study treatment administration. Peripheral neuropathy ≥grade 2. Any prior treatment with monomethyl auristatin E (MMAE)-containing drugs. There are additional inclusion and exclusion criteria. The study center will determine if criteria for participation are met.
Central Contact Person:
First Name & Middle Initial & Last Name or Official Title & Degree
Seagen Trial Information Support
Phone
8663337436
Email
clinicaltrials@seagen.com
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Leo Nicacio, MD
Organizational Affiliation
Seagen Inc.
Official's Role
Study Director
First Name & Middle Initial & Last Name & Degree
Liz Whalley, PhD
Organizational Affiliation
Seagen Inc.
Official's Role
Study Director
Facility Information:
Facility Name
University of Alabama at Birmingham
City
Birmingham
State/Province
Alabama
ZIP/Postal Code
35294-3300
Country
United States
Individual Site Status
Completed
Facility Name
Arizona Oncology Associates, PC - HAL
City
Phoenix
State/Province
Arizona
ZIP/Postal Code
85016
Country
United States
Individual Site Status
Completed
Facility Name
Arizona Oncology Associates, PC - HOPE
City
Tucson
State/Province
Arizona
ZIP/Postal Code
85710
Country
United States
Individual Site Status
Completed
Facility Name
University of California Irvine Medical Center
City
Irvine
State/Province
California
ZIP/Postal Code
92697
Country
United States
Individual Site Status
Active, not recruiting
Facility Name
Olive View - UCLA Medical Center
City
Sylmar
State/Province
California
ZIP/Postal Code
91342
Country
United States
Individual Site Status
Active, not recruiting
Facility Name
Yale Cancer Center
City
New Haven
State/Province
Connecticut
ZIP/Postal Code
06520
Country
United States
Individual Site Status
Active, not recruiting
Facility Name
Broward Health Medical Center
City
Fort Lauderdale
State/Province
Florida
ZIP/Postal Code
33316
Country
United States
Individual Site Status
Active, not recruiting
Facility Name
Augusta University
City
Augusta
State/Province
Georgia
ZIP/Postal Code
30912
Country
United States
Individual Site Status
Active, not recruiting
Facility Name
Northwestern Memorial Hospital
City
Chicago
State/Province
Illinois
ZIP/Postal Code
60611
Country
United States
Individual Site Status
Completed
Facility Name
Gynecological Cancer Institute of Chicago, LLC
City
Oak Lawn
State/Province
Illinois
ZIP/Postal Code
60453
Country
United States
Individual Site Status
Completed
Facility Name
Norton Cancer Institute
City
Louisville
State/Province
Kentucky
ZIP/Postal Code
40207
Country
United States
Individual Site Status
Active, not recruiting
Facility Name
Willis-Knighton Physician Network/Gynecologic Oncology Associates
City
Shreveport
State/Province
Louisiana
ZIP/Postal Code
71103
Country
United States
Individual Site Status
Completed
Facility Name
Maryland Oncology Hematology, P.A.
City
Columbia
State/Province
Maryland
ZIP/Postal Code
21044
Country
United States
Individual Site Status
Completed
Facility Name
Minnesota Oncology Hematology P.A.
City
Minneapolis
State/Province
Minnesota
ZIP/Postal Code
55404
Country
United States
Individual Site Status
Active, not recruiting
Facility Name
St. Dominic - Jackson Memorial Hospital
City
Jackson
State/Province
Mississippi
ZIP/Postal Code
39216
Country
United States
Individual Site Status
Active, not recruiting
Facility Name
Washington University in St Louis
City
Saint Louis
State/Province
Missouri
ZIP/Postal Code
63108
Country
United States
Individual Site Status
Active, not recruiting
Facility Name
Holy Name Medical Center
City
Teaneck
State/Province
New Jersey
ZIP/Postal Code
07666
Country
United States
Individual Site Status
Completed
Facility Name
Weill Cornell Medicine
City
Brooklyn
State/Province
New York
ZIP/Postal Code
11215
Country
United States
Individual Site Status
Completed
Facility Name
Weill Cornell Medicine
City
Flushing
State/Province
New York
ZIP/Postal Code
11355
Country
United States
Individual Site Status
Completed
Facility Name
New York University (NYU) Cancer Institute
City
New York
State/Province
New York
ZIP/Postal Code
10016
Country
United States
Individual Site Status
Completed
Facility Name
UNC Lineberger Comprehensive Cancer Center / University of North Carolina
City
Chapel Hill
State/Province
North Carolina
ZIP/Postal Code
27599
Country
United States
Individual Site Status
Completed
Facility Name
Cleveland Clinic Fairview Hospital
City
Cleveland
State/Province
Ohio
ZIP/Postal Code
44111
Country
United States
Individual Site Status
Active, not recruiting
Facility Name
Cleveland Clinic, The
City
Cleveland
State/Province
Ohio
ZIP/Postal Code
44195
Country
United States
Individual Site Status
Active, not recruiting
Facility Name
Ohio State University Clinical Trials Management Office
City
Hilliard
State/Province
Ohio
ZIP/Postal Code
43026
Country
United States
Individual Site Status
Active, not recruiting
Facility Name
Kettering Health
City
Kettering
State/Province
Ohio
ZIP/Postal Code
45429
Country
United States
Individual Site Status
Completed
Facility Name
Cleveland Clinic Hillcrest Hospital
City
Mayfield Heights
State/Province
Ohio
ZIP/Postal Code
44124
Country
United States
Individual Site Status
Active, not recruiting
Facility Name
Oncology Associates of Oregon
City
Eugene
State/Province
Oregon
ZIP/Postal Code
97401
Country
United States
Individual Site Status
Completed
Facility Name
Northwest Cancer Specialists, P.C.
City
Portland
State/Province
Oregon
ZIP/Postal Code
97227
Country
United States
Individual Site Status
Completed
Facility Name
Texas Oncology - Austin Central
City
Austin
State/Province
Texas
ZIP/Postal Code
78731
Country
United States
Individual Site Status
Completed
Facility Name
Texas Oncology - Fort Worth 12th Avenue
City
Fort Worth
State/Province
Texas
ZIP/Postal Code
76104
Country
United States
Individual Site Status
Active, not recruiting
Facility Name
Texas Oncology - The Woodlands
City
The Woodlands
State/Province
Texas
ZIP/Postal Code
77380
Country
United States
Individual Site Status
Completed
Facility Name
Texas Oncology - Tyler
City
Tyler
State/Province
Texas
ZIP/Postal Code
75702
Country
United States
Individual Site Status
Completed
Facility Name
University of Virginia
City
Charlottesville
State/Province
Virginia
ZIP/Postal Code
22901
Country
United States
Individual Site Status
Active, not recruiting
Facility Name
Virginia Oncology Associates
City
Norfolk
State/Province
Virginia
ZIP/Postal Code
23502
Country
United States
Individual Site Status
Completed
Facility Name
Virginia Commonwealth University Medical Center
City
Richmond
State/Province
Virginia
ZIP/Postal Code
23219
Country
United States
Individual Site Status
Active, not recruiting
Facility Name
Carbone Cancer Center / University of Wisconsin
City
Madison
State/Province
Wisconsin
ZIP/Postal Code
53792
Country
United States
Individual Site Status
Completed
Facility Name
Instituto Oncologico de Cordoba
City
Córdoba
State/Province
Other
ZIP/Postal Code
X5006HBF
Country
Argentina
Individual Site Status
Active, not recruiting
Facility Name
Fundacion Cenit
City
Caba
ZIP/Postal Code
1125
Country
Argentina
Individual Site Status
Active, not recruiting
Facility Name
Instituto Alexander Fleming
City
Caba
ZIP/Postal Code
1426
Country
Argentina
Individual Site Status
Active, not recruiting
Facility Name
Sanatorio de la Mujer
City
Rosario
ZIP/Postal Code
2000
Country
Argentina
Individual Site Status
Active, not recruiting
Facility Name
LKH- Universitat Klinikum Graz
City
Graz
State/Province
Other
ZIP/Postal Code
8036
Country
Austria
Individual Site Status
Completed
Facility Name
AKH - Medizinische Universitat Wien
City
Vienna
State/Province
Other
ZIP/Postal Code
1090
Country
Austria
Individual Site Status
Active, not recruiting
Facility Name
Institut Jules Bordet
City
Anderlecht
State/Province
Other
ZIP/Postal Code
B-1070
Country
Belgium
Individual Site Status
Active, not recruiting
Facility Name
ZNA Middelheim
City
Antwerpen
State/Province
Other
ZIP/Postal Code
2020
Country
Belgium
Individual Site Status
Active, not recruiting
Facility Name
Cliniques Universitaires Saint Luc
City
Brussels
State/Province
Other
ZIP/Postal Code
1200
Country
Belgium
Individual Site Status
Active, not recruiting
Facility Name
Universitair Ziekenhuis Gent
City
Gent
State/Province
Other
ZIP/Postal Code
9000
Country
Belgium
Individual Site Status
Active, not recruiting
Facility Name
UZ Leuven campus Gasthuisberg
City
Leuven
State/Province
Other
ZIP/Postal Code
3000
Country
Belgium
Individual Site Status
Active, not recruiting
Facility Name
CHU de Liege
City
Liege
State/Province
Other
ZIP/Postal Code
4000
Country
Belgium
Individual Site Status
Active, not recruiting
Facility Name
CHU UCL Namur-Site de Saint Elisabeth
City
Namur
State/Province
Other
ZIP/Postal Code
5000
Country
Belgium
Individual Site Status
Active, not recruiting
Facility Name
Grand Hopital de Charleroi
City
Charleroi
ZIP/Postal Code
6000
Country
Belgium
Individual Site Status
Completed
Facility Name
Hospital Mãe de Deus
City
Porto Alegre
State/Province
Other
ZIP/Postal Code
90110-270
Country
Brazil
Individual Site Status
Active, not recruiting
Facility Name
Erasto Gaertner Hospital
City
CuriBba
ZIP/Postal Code
81520-060
Country
Brazil
Individual Site Status
Active, not recruiting
Facility Name
Instituto Brasileiro de Controle do Cancer
City
Formosa
ZIP/Postal Code
73801-340
Country
Brazil
Individual Site Status
Active, not recruiting
Facility Name
Hospital de Caridade de Ijuí
City
Ijuí
Country
Brazil
Individual Site Status
Active, not recruiting
Facility Name
Centro de PesquisaemOncologia - HSL-PUCRS
City
Porto Alegre, Rio Grande Do Sul
ZIP/Postal Code
90610-000
Country
Brazil
Individual Site Status
Active, not recruiting
Facility Name
Brazilian National Cancer Institute
City
Rio de Janeiro
ZIP/Postal Code
20220---280
Country
Brazil
Individual Site Status
Active, not recruiting
Facility Name
Fundação NAtonio Prudente (AC Camargo Cancer Center)
City
Sao Paulo
ZIP/Postal Code
01509-010
Country
Brazil
Individual Site Status
Active, not recruiting
Facility Name
Hospital Beneficencia Portuguesa
City
São Paulo
ZIP/Postal Code
01323-001
Country
Brazil
Individual Site Status
Active, not recruiting
Facility Name
University of Alberta / Cross Cancer Institute
City
Edmonton
State/Province
Alberta
ZIP/Postal Code
T6G 1Z2
Country
Canada
Individual Site Status
Active, not recruiting
Facility Name
British Columbia Cancer Agency - Vancouver Centre
City
Vancouver
State/Province
British Columbia
ZIP/Postal Code
V5Z 4E6
Country
Canada
Individual Site Status
Active, not recruiting
Facility Name
Sunnybrook Health Sciences Centre
City
Toronto
State/Province
Ontario
ZIP/Postal Code
M4N 3M5
Country
Canada
Individual Site Status
Active, not recruiting
Facility Name
University Health Network, Princess Margaret Hospital
City
Toronto
State/Province
Ontario
ZIP/Postal Code
M5G 2M9
Country
Canada
Individual Site Status
Active, not recruiting
Facility Name
Centre Hospitalier de l'Universite de Montreal
City
Montreal
State/Province
Quebec
ZIP/Postal Code
H2X 3E4
Country
Canada
Individual Site Status
Completed
Facility Name
Saskatoon Cancer Centre
City
Saskatoon
State/Province
Saskatchewan
ZIP/Postal Code
S7N 4H4
Country
Canada
Individual Site Status
Completed
Facility Name
Cancer Hospital Chinese Academy of Medical Sciences
City
Beijing
State/Province
Other
ZIP/Postal Code
100021
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Lingying Wu
Facility Name
Beijing Obstetrics and Gynecology Hospital
City
Beijing
State/Province
Other
ZIP/Postal Code
100026
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Weimin Kong
Facility Name
Peking University People's Hospital
City
Beijing
State/Province
Other
ZIP/Postal Code
100044
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Jianliu Wang
Facility Name
Jilin University - First Affiliated Hospital - Cancer Center
City
Changchun
State/Province
Other
ZIP/Postal Code
130000
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Ziling Liu
Facility Name
The Third Xiangya Hospital of Central South University
City
Changsha
State/Province
Other
ZIP/Postal Code
410008
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Hong Zhu
Facility Name
Chongqing Cancer Hospital
City
Chongqing
State/Province
Other
ZIP/Postal Code
400030
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Qi Zhou
Facility Name
Shandong Cancer Hospital
City
Jinan
State/Province
Other
ZIP/Postal Code
250117
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Dapeng Li
Facility Name
Shanghai First People's Hospital
City
Shanghai
State/Province
Other
ZIP/Postal Code
200060
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Yaping Zhu
Facility Name
The Second Hospital of Shanxi Medical University
City
Taiyuan
State/Province
Other
ZIP/Postal Code
030001
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Min Hao
Facility Name
The Affiliated Cancer Hospital of XinJiang Medical University
City
Urumqi
State/Province
Other
ZIP/Postal Code
830054
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Jianlin Yuan
Facility Name
Union Hospital affiliated to Tongji Medical College of Huazhong University of Science and Technology
City
Wuhan City
State/Province
Other
ZIP/Postal Code
430030
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Guiling Li
Facility Name
Hubei Cancer Hospital
City
Wuhan
State/Province
Other
ZIP/Postal Code
430000
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Huifeng Zhang
Facility Name
Shaanxi Provincial People's Hospital
City
Xi'an
State/Province
Other
ZIP/Postal Code
710068
Country
China
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Lihong Chen
Facility Name
Fakultni nemocnice Brno
City
Brno-stred-Veveri
State/Province
Other
ZIP/Postal Code
602 00
Country
Czechia
Individual Site Status
Active, not recruiting
Facility Name
Fakultni Nemocnice Olomouc (Fnol) - Onkologicka Klinika
City
Olomouc
State/Province
Other
ZIP/Postal Code
779 00
Country
Czechia
Individual Site Status
Active, not recruiting
Facility Name
General University Hospital Prague
City
Praha 2
State/Province
Other
ZIP/Postal Code
120 00
Country
Czechia
Individual Site Status
Active, not recruiting
Facility Name
Hospital Na Bulovce
City
Praha 8-Liben
State/Province
Other
ZIP/Postal Code
18081
Country
Czechia
Individual Site Status
Active, not recruiting
Facility Name
Rigshospitalet
City
Kobenhavn
State/Province
Other
ZIP/Postal Code
2100
Country
Denmark
Individual Site Status
Completed
Facility Name
University of Turku
City
Turku
State/Province
Other
ZIP/Postal Code
20520
Country
Finland
Individual Site Status
Active, not recruiting
Facility Name
Kuopio University Hospital
City
Kuopio
ZIP/Postal Code
70210
Country
Finland
Individual Site Status
Completed
Facility Name
Tampere University Hospital
City
Tampere
ZIP/Postal Code
33520
Country
Finland
Individual Site Status
Completed
Facility Name
Centre Hospitalier Regional et Universitaire de Besancon - Hopital Jean-Minjoz
City
Besancon Cedex
State/Province
Other
ZIP/Postal Code
25000
Country
France
Individual Site Status
Active, not recruiting
Facility Name
Centre de Lutte Contre le Cancer (CLCC) - Institut Bergonie
City
Bordeaux
State/Province
Other
ZIP/Postal Code
33000
Country
France
Individual Site Status
Active, not recruiting
Facility Name
Centre de Lutte contre le Cancer - François Baclesse
City
Caen Cedex 5
State/Province
Other
ZIP/Postal Code
14076
Country
France
Individual Site Status
Active, not recruiting
Facility Name
CARIO - Centre Armoricain De Radiothérapie, D'imagerie Médicale Et D'oncologie
City
Cotes d'Armor
State/Province
Other
ZIP/Postal Code
22190
Country
France
Individual Site Status
Active, not recruiting
Facility Name
Institute Cancer De Lorraine (ICL) - Alexis Vautrin
City
Moselle
State/Province
Other
ZIP/Postal Code
54519
Country
France
Individual Site Status
Active, not recruiting
Facility Name
Hopital Prive du Confluent
City
Nantes Cedex 2
State/Province
Other
ZIP/Postal Code
44277
Country
France
Individual Site Status
Active, not recruiting
Facility Name
Groupe Hospitalier Diaconesses Croix Saint-Simon - Site Avron (Hopital de la Croix Saint-Simon)
City
Paris
State/Province
Other
ZIP/Postal Code
75020
Country
France
Individual Site Status
Active, not recruiting
Facility Name
Institut de cancerologie Strasbourg Europe
City
Strasbourg
State/Province
Other
ZIP/Postal Code
67200
Country
France
Individual Site Status
Active, not recruiting
Facility Name
Institut Claudius Regaud IUCT-O
City
Toulouse Cedex 9
State/Province
Other
ZIP/Postal Code
31059
Country
France
Individual Site Status
Active, not recruiting
Facility Name
Institut Gustave Roussy
City
Villejuif Cedex
State/Province
Other
ZIP/Postal Code
94805
Country
France
Individual Site Status
Active, not recruiting
Facility Name
Kliniken Essen-Mitte
City
Essen
State/Province
Other
ZIP/Postal Code
45136
Country
Germany
Individual Site Status
Active, not recruiting
Facility Name
Universitaetsklinikum Essen
City
Essen
State/Province
Other
ZIP/Postal Code
45147
Country
Germany
Individual Site Status
Active, not recruiting
Facility Name
Universitaetsklinikum Hamburg-Eppendorf (UKE)
City
Hamburg
State/Province
Other
ZIP/Postal Code
20246
Country
Germany
Individual Site Status
Active, not recruiting
Facility Name
University Hospital LMU Munich
City
Munchen
State/Province
Other
ZIP/Postal Code
81377
Country
Germany
Individual Site Status
Active, not recruiting
Facility Name
National Institute of Oncology Hungary
City
Budapest, Pest
State/Province
Other
ZIP/Postal Code
1122
Country
Hungary
Individual Site Status
Active, not recruiting
Facility Name
Medical and Health Science Centre Debrecen Institution of Internal Medicine
City
Debrecen, Hajdú-Bihar
State/Province
Other
ZIP/Postal Code
4032
Country
Hungary
Individual Site Status
Active, not recruiting
Facility Name
Bacs-Kiskun Varmegyei Oktatokorhaz
City
Kecskemet
State/Province
Other
ZIP/Postal Code
H6000
Country
Hungary
Individual Site Status
Active, not recruiting
Facility Name
University Hospital Waterford
City
Waterford
State/Province
Other
ZIP/Postal Code
X91 ER8E
Country
Ireland
Individual Site Status
Completed
Facility Name
Azienda Ospedaliera per l'Emergenza
City
Catania
State/Province
Other
ZIP/Postal Code
95126
Country
Italy
Individual Site Status
Active, not recruiting
Facility Name
Ospedale San Raffaele
City
Milano
State/Province
Other
ZIP/Postal Code
20132
Country
Italy
Individual Site Status
Active, not recruiting
Facility Name
Fondazione Policlinico Universitario Agostino
City
Roma
State/Province
Other
ZIP/Postal Code
00168
Country
Italy
Individual Site Status
Active, not recruiting
Facility Name
Hospital San Bortolo
City
Vicenza
State/Province
Other
ZIP/Postal Code
36100
Country
Italy
Individual Site Status
Active, not recruiting
Facility Name
IRCCS Istituto Romagnolo per lo Studio dei Tumori Dino Amadori- IRST S.r.l
City
Meldola
ZIP/Postal Code
47014
Country
Italy
Individual Site Status
Completed
Facility Name
National Cancer Center Hospital
City
Chuo-ku
State/Province
Other
ZIP/Postal Code
104-0045
Country
Japan
Individual Site Status
Active, not recruiting
Facility Name
Kurume University Hospital
City
Fukuoka
State/Province
Other
ZIP/Postal Code
830-0011
Country
Japan
Individual Site Status
Completed
Facility Name
Gunma University Hospital
City
Gunma
State/Province
Other
ZIP/Postal Code
371-8511
Country
Japan
Individual Site Status
Active, not recruiting
Facility Name
Saitama Cancer Center
City
Hidaka-City
State/Province
Other
Country
Japan
Individual Site Status
Active, not recruiting
Facility Name
Kagoshima University Hospital
City
Kagoshima City
State/Province
Other
ZIP/Postal Code
890-8520
Country
Japan
Individual Site Status
Active, not recruiting
Facility Name
Kagoshima City Hospital
City
Kagoshima-City
State/Province
Other
ZIP/Postal Code
890-8760
Country
Japan
Individual Site Status
Active, not recruiting
Facility Name
National Cancer Center Hospital East
City
Kashiwa-shi
State/Province
Other
ZIP/Postal Code
277-8577
Country
Japan
Individual Site Status
Active, not recruiting
Facility Name
The Jikei University Kashiwa Hospital
City
Kashiwashi
State/Province
Other
ZIP/Postal Code
277-8567
Country
Japan
Individual Site Status
Active, not recruiting
Facility Name
NHO Shikoku Cancer Center
City
Matsuyama
State/Province
Other
ZIP/Postal Code
791-0280
Country
Japan
Individual Site Status
Completed
Facility Name
Aichi Cancer Center
City
Nagoya-shi
State/Province
Other
ZIP/Postal Code
464-8681
Country
Japan
Individual Site Status
Active, not recruiting
Facility Name
University of the Ryukyus Hospital
City
Nakagami-gun
State/Province
Other
ZIP/Postal Code
903-0215
Country
Japan
Individual Site Status
Active, not recruiting
Facility Name
Okayama University Hospital
City
Okayama
State/Province
Other
ZIP/Postal Code
700-8558
Country
Japan
Individual Site Status
Active, not recruiting
Facility Name
Kindai University Hospital
City
Osakasayama
State/Province
Other
ZIP/Postal Code
589-8511
Country
Japan
Individual Site Status
Completed
Facility Name
Osaka International Cancer Institute
City
Osaka
State/Province
Other
ZIP/Postal Code
541-8567
Country
Japan
Individual Site Status
Active, not recruiting
Facility Name
National Hospital Organization Hokkaido Cancer Center
City
Sapporo-shi
State/Province
Other
ZIP/Postal Code
003-0804
Country
Japan
Individual Site Status
Active, not recruiting
Facility Name
Hokkaido University Hospital
City
Sapporo-shi
State/Province
Other
Country
Japan
Individual Site Status
Active, not recruiting
Facility Name
Shizuoka Cancer Center
City
Sunto-Gun
State/Province
Other
ZIP/Postal Code
411-8777
Country
Japan
Individual Site Status
Active, not recruiting
Facility Name
The Cancer Institute Hospital of JFCR
City
Tokyo
State/Province
Other
ZIP/Postal Code
135-8550
Country
Japan
Individual Site Status
Active, not recruiting
Facility Name
Keio University Hospital
City
Tokyo
State/Province
Other
ZIP/Postal Code
160-8582
Country
Japan
Individual Site Status
Active, not recruiting
Facility Name
Kanagawa Cancer Center
City
Yokohama
State/Province
Other
ZIP/Postal Code
241-8515
Country
Japan
Individual Site Status
Completed
Facility Name
Hyogo Cancer Center
City
Akashi
ZIP/Postal Code
673-8558
Country
Japan
Individual Site Status
Active, not recruiting
Facility Name
Ehime University Hospital
City
Ehime
Country
Japan
Individual Site Status
Active, not recruiting
Facility Name
National Hospital Organization Kure Medical Center and Chugoku Cancer Center
City
Hiroshima
ZIP/Postal Code
737-0023
Country
Japan
Individual Site Status
Completed
Facility Name
Nippon Medical School Musashi Kosugi Hospital
City
Kanagawa
ZIP/Postal Code
211-8533
Country
Japan
Individual Site Status
Active, not recruiting
Facility Name
Niigata Cancer Center Hospital
City
Niigata
ZIP/Postal Code
951-8133
Country
Japan
Individual Site Status
Completed
Facility Name
Iwate Medical University Hospital
City
Shiwa-gun
ZIP/Postal Code
028-3695
Country
Japan
Individual Site Status
Active, not recruiting
Facility Name
Jikei University Hospital
City
Tokyo
ZIP/Postal Code
105-0003
Country
Japan
Individual Site Status
Completed
Facility Name
Yokohama City University Hospital
City
Yokohama
ZIP/Postal Code
232-0024
Country
Japan
Individual Site Status
Completed
Facility Name
Keimyung University Dongsan Medical Center
City
Daegu
State/Province
Other
ZIP/Postal Code
42601
Country
Korea, Republic of
Individual Site Status
Active, not recruiting
Facility Name
National Cancer Center
City
Goyang-si
State/Province
Other
ZIP/Postal Code
10408
Country
Korea, Republic of
Individual Site Status
Active, not recruiting
Facility Name
Seoul National University Bundang Hospital
City
Seongnam-si
State/Province
Other
ZIP/Postal Code
13605
Country
Korea, Republic of
Individual Site Status
Active, not recruiting
Facility Name
CHA Bundang Medical Center
City
Seongnam
State/Province
Other
ZIP/Postal Code
13496
Country
Korea, Republic of
Individual Site Status
Active, not recruiting
Facility Name
Korea Cancer Center Hospital
City
Seoul
State/Province
Other
ZIP/Postal Code
01802
Country
Korea, Republic of
Individual Site Status
Completed
Facility Name
Seoul National University Hospital
City
Seoul
State/Province
Other
ZIP/Postal Code
03080
Country
Korea, Republic of
Individual Site Status
Active, not recruiting
Facility Name
Soon Chun Hyang University Hospital Seoul
City
Seoul
State/Province
Other
ZIP/Postal Code
04401
Country
Korea, Republic of
Individual Site Status
Active, not recruiting
Facility Name
Asan Medical Center
City
Seoul
State/Province
Other
ZIP/Postal Code
05505
Country
Korea, Republic of
Individual Site Status
Active, not recruiting
Facility Name
Samsung Medical Center
City
Seoul
State/Province
Other
ZIP/Postal Code
06351
Country
Korea, Republic of
Individual Site Status
Active, not recruiting
Facility Name
Seoul Saint Mary's Hospital
City
Seoul
State/Province
Other
ZIP/Postal Code
06591
Country
Korea, Republic of
Individual Site Status
Completed
Facility Name
Ewha Womans University Mokdong Hospital
City
Seoul
State/Province
Other
ZIP/Postal Code
07985
Country
Korea, Republic of
Individual Site Status
Completed
Facility Name
Severance Hospital, Yonsei University Health System
City
Seoul
State/Province
Other
ZIP/Postal Code
120-752
Country
Korea, Republic of
Individual Site Status
Active, not recruiting
Facility Name
Inje University Busan-Paik Hospital
City
Busan
ZIP/Postal Code
47392
Country
Korea, Republic of
Individual Site Status
Completed
Facility Name
Sungkyunkwan University of Medicine - Samsung Changwon Hospital
City
Changwon, Kyungsangnam-do
ZIP/Postal Code
51353
Country
Korea, Republic of
Individual Site Status
Active, not recruiting
Facility Name
Gangnam Severance Hospital
City
Seoul
ZIP/Postal Code
06273
Country
Korea, Republic of
Individual Site Status
Active, not recruiting
Facility Name
Oncologico Potosino
City
San Luis Potosí
ZIP/Postal Code
78209
Country
Mexico
Individual Site Status
Active, not recruiting
Facility Name
Amsterdam UMC, Locatie AMC
City
Amsterdam
State/Province
Other
ZIP/Postal Code
1105 AZ
Country
Netherlands
Individual Site Status
Active, not recruiting
Facility Name
Maastricht University Medical Center
City
Maastricht
State/Province
Other
ZIP/Postal Code
6229 HX
Country
Netherlands
Individual Site Status
Active, not recruiting
Facility Name
Radboud University Medical Center
City
Nijmegen
State/Province
Other
ZIP/Postal Code
6525 GA
Country
Netherlands
Individual Site Status
Active, not recruiting
Facility Name
Erasmus Medisch Centrum Daniel Den Hoed
City
Rotterdam
State/Province
Other
ZIP/Postal Code
3015GD
Country
Netherlands
Individual Site Status
Active, not recruiting
Facility Name
Universitair Medisch Centrum Utrecht
City
Utrecht
State/Province
Other
ZIP/Postal Code
3584 CX
Country
Netherlands
Individual Site Status
Active, not recruiting
Facility Name
Oslo University Hospital, Radiumhospitalet
City
Olso
State/Province
Other
ZIP/Postal Code
0379
Country
Norway
Individual Site Status
Active, not recruiting
Facility Name
Trondheim University Hospital, Trondheim
City
Trondheim
ZIP/Postal Code
7030
Country
Norway
Individual Site Status
Completed
Facility Name
Hospital Maria Auxiliadora
City
Lima
ZIP/Postal Code
15081
Country
Peru
Individual Site Status
Active, not recruiting
Facility Name
Białostockie Centrum Onkologii
City
Białystok
State/Province
Other
ZIP/Postal Code
15-027
Country
Poland
Individual Site Status
Active, not recruiting
Facility Name
National University Cancer Institute, Singapore
City
Singapore
State/Province
Other
ZIP/Postal Code
119228
Country
Singapore
Individual Site Status
Active, not recruiting
Facility Name
National Cancer Centre Singapore
City
Singapore
State/Province
Other
ZIP/Postal Code
169610
Country
Singapore
Individual Site Status
Active, not recruiting
Facility Name
Hospital Universitari Vall d'Hebron
City
Barcelona
State/Province
Other
ZIP/Postal Code
08035
Country
Spain
Individual Site Status
Active, not recruiting
Facility Name
Hospital Clinic de Barcelona
City
Barcelona
State/Province
Other
ZIP/Postal Code
08036
Country
Spain
Individual Site Status
Active, not recruiting
Facility Name
Hospital Universitario Reina Sofia
City
Cordoba
State/Province
Other
ZIP/Postal Code
14004
Country
Spain
Individual Site Status
Active, not recruiting
Facility Name
Clinica Universidad de Navarra
City
Madrid
State/Province
Other
ZIP/Postal Code
28027
Country
Spain
Individual Site Status
Active, not recruiting
Facility Name
Hospital Universitario 12 de Octubre
City
Madrid
State/Province
Other
ZIP/Postal Code
28041
Country
Spain
Individual Site Status
Active, not recruiting
Facility Name
Hospital Universitario La Paz
City
Madrid
State/Province
Other
ZIP/Postal Code
28046
Country
Spain
Individual Site Status
Active, not recruiting
Facility Name
Clinica Universidad de Navarra
City
Pamplona
State/Province
Other
ZIP/Postal Code
31008
Country
Spain
Individual Site Status
Active, not recruiting
Facility Name
Hospital Clinico Universitario de Valencia
City
Valencia
State/Province
Other
ZIP/Postal Code
46010
Country
Spain
Individual Site Status
Active, not recruiting
Facility Name
Linkoping University Hospital
City
Linköping
State/Province
Other
ZIP/Postal Code
581 85
Country
Sweden
Individual Site Status
Active, not recruiting
Facility Name
Skanes University Hospital - Universitetssjukhus
City
Lund
State/Province
Other
ZIP/Postal Code
221 85
Country
Sweden
Individual Site Status
Active, not recruiting
Facility Name
Uppsala University Hospital (Akademiska Sjukhuset)
City
Uppsala
State/Province
Other
ZIP/Postal Code
75185
Country
Sweden
Individual Site Status
Active, not recruiting
Facility Name
Mackay Memorial Hospital
City
Taipei City
State/Province
Other
ZIP/Postal Code
10449
Country
Taiwan
Individual Site Status
Active, not recruiting
Facility Name
Chang Gung Memorial Hospital - Linkou
City
Taoyuan
State/Province
Other
ZIP/Postal Code
333
Country
Taiwan
Individual Site Status
Active, not recruiting
Facility Name
Taipei Veterans General Hospital
City
Taipei City
ZIP/Postal Code
11217
Country
Taiwan
Individual Site Status
Active, not recruiting
Facility Name
Cambridge University Hospitals NHS Foundation Trust
City
Cambridge
State/Province
Other
ZIP/Postal Code
CB2 0QQ
Country
United Kingdom
Individual Site Status
Active, not recruiting
Facility Name
Royal Devon and Exeter NHS Foundation Trust
City
Exeter
State/Province
Other
ZIP/Postal Code
EX2 5DW
Country
United Kingdom
Individual Site Status
Completed
Facility Name
The Royal Marsden Hospital
City
London
State/Province
Other
ZIP/Postal Code
SW3 6JJ
Country
United Kingdom
Individual Site Status
Active, not recruiting
Facility Name
The Christie NHS Foundation Trust
City
Manchester
State/Province
Other
ZIP/Postal Code
M20 4BX
Country
United Kingdom
Individual Site Status
Active, not recruiting
Facility Name
The Royal Marsden Hospital (Surrey)
City
Sutton
State/Province
Other
ZIP/Postal Code
SM2 5PT
Country
United Kingdom
Individual Site Status
Active, not recruiting
Facility Name
The Beatson West of Scotland Cancer Centre
City
Glasgow
ZIP/Postal Code
G12 0YN
Country
United Kingdom
Individual Site Status
Completed

12. IPD Sharing Statement

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Tisotumab Vedotin vs Chemotherapy in Recurrent or Metastatic Cervical Cancer

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