Radiotherapy for Keloids
Keloid
About this trial
This is an interventional treatment trial for Keloid
Eligibility Criteria
Inclusion Criteria:
Clinically diagnosed keloid -Surgical excision of keloid is either contraindicated or patient has declined treatment with surgical excision. Note: patients with keloids that recurred after previous resection are eligible, as long as the current keloid is either unresectable or patient has decline resection.
- Age ≥18
- Study specific informed consent provided
Exclusion Criteria:
- Prior RT to the area of interest that would result in overlap of radiation therapy fields
- Females of child bearing age without a negative serum pregnancy test prior to initiation of RT or unwilling to use contraception prior to and during the radiation course
- Keloids in areas where radiation therapy introduces unacceptable high risk of toxicity as determined by the treating radiation oncologist
- Uncontrolled intercurrent illness (e.g. symptomatic congestive heart failure, uncontrolled cardiac arrhythmia, or psychiatric situation) that would limit compliance with study requirements as judged by the treatment physicians
Sites / Locations
- Montefiore Medical CenterRecruiting
Arms of the Study
Arm 1
Experimental
Radiotherapy for patients with nonresectable keloids
Patients will be seen by a treating radiation oncologist and treatment with the assigned dose schedule will be planned using either EBRT with electrons or high dose-rate radiotherapy (HDR) brachytherapy as deemed appropriate by the treating radiation oncologist. The treatment dose of 15 Gy in 3 fractions will be prescribed to the 90% isodose line.