Dentifrice With Innovative Remineralizing Technology (REFIX)
Initial Dental Caries
About this trial
This is an interventional prevention trial for Initial Dental Caries focused on measuring caries, white spot lesions, fluoride
Eligibility Criteria
Inclusion Criteria:
- The eligibility criteria were people over 18 years old, without systemic commitment and living in the city of João Pessoa-Paraíba, without water fluoridation (< 0.1 μg/mL F).
Exclusion Criteria:
- Individuals were excluded if they used drugs that interfere with biofilm formation and salivary flow or fluoride products (> 5000 ppm) in the last 4 weeks, used orthodontic appliances, or had cavity lesions, periodontal disease, and/or tooth sensitivity.
Sites / Locations
- Federal University of ParaíbaRecruiting
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Arm 5
Placebo Comparator
Sham Comparator
Active Comparator
Experimental
Active Comparator
G0 - placebo
G1: Daily Regenerator Dentalclean Neutro (RDCN)
G2: Sensodyne Repair & Protect (SRP)
G3: Daily Regenerator Dentalclean Acid (RDCA)
G4: Colgate Total Daily Repair (CTDR)
Dental gel without fluoride in the composition
1450 ppm F- of sodium fluoride and tetrasodium pyrophosphate (Refix technology). NEUTRAL pH
1426 ppm of sodium fluoride and calcium sodium phosphosilicate 5% (NOVAMIN technology).
1450 ppm F- of sodium fluoride and tetrasodium pyrophosphate (Refix technology). ACIDIC FORMULA
1450 ppm F- of as sodium fluoride, 0.30% triclosan, arginine, tetrasodium pyrophosphate.