Promoting HIV Risk Reduction Among People Who Inject Drugs: A Stepped Care Approach Using Contingency Management With PrEP Adherence and Support Services (CoMPASS)
Opioid-use Disorder, HIV Prevention Program
About this trial
This is an interventional treatment trial for Opioid-use Disorder focused on measuring People who inject drugs, Pre-exposure prophylaxis (PrEP), Medications for opioid use disorder, Opioid use disorder, HIV prevention
Eligibility Criteria
Inclusion Criteria:
Aims 1 and 2:
- Receive or willing to receive care at one of the participating study sites
- Have a recent negative HIV test with no concern for acute HIV
- Report injection drug use in the past 6 months
- Meet PrEP eligibility criteria by either a) sharing of injection or drug preparation equipment; b) sexual risk behaviors (i.e. condomless sex or STI) in the past 6 months
- Meet Diagnostic and Statistical Manual of Mental Disorders - 5th edition (DSM5) criteria for opioid use disorder
- Have a cell phone or use of a household member's cell phone
- Provide written informed consent
Aim 3:
- Currently employed at one of the participating study sites
- Willing to complete a web-based survey
Exclusion criteria:
Aims 1 and 2:
- Currently prescribed PrEP
- Self-report or urine test confirming pregnancy, breastfeeding, or trying to conceive
- Any plans that would preclude study completion (surgery, major medical treatment or conditions, incarceration, travel out of state or country.)
- Inability to provide at least one collateral contact for a friend or family member.
- Non-English speaking (for sites without Spanish-speaking staff)
- Have kidney disease (a contraindication to PrEP)
Aim 3:
1. Non-English speaking
Sites / Locations
- Recovery Network of Programs, IncRecruiting
- Liberations Program, IncRecruiting
- Apex Community Care. Inc.Recruiting
- Greater Hartford Harm Reduction Coalition- SWANRecruiting
- APTRecruiting
- Stanley Street Treatment and Resource CenterRecruiting
Arms of the Study
Arm 1
Arm 2
No Intervention
Experimental
Treatment as Usual (TAU)
Contingency Management with stepped care to PrEP Adherence and Support Services (CoMPASS)
Participants randomized to TAU will receive a health handout on HIV risk reduction approaches, including PrEP and OUD-related care, and where to access such services. They will receive standard care as provided by the community-based organization and by their medical provider.
Participants randomized to Compass will also receive a health handout on HIV risk reduction approaches. They will also receive contingency management sessions (n=9). Participants who do not demonstrate PrEP adherence by week 12, will be "stepped up" to receive PrEP adherence and support services (n=5).