Clinical Evaluation of New Treatment Strategy of Mucous Membrane Pemphigoid Using Large Dose of Prednisolone Plus Intra-lesional of Triamcinolone Acetonide Followed by Combination of Mycophenolate Mofetil, Dapsone and Low Dose Prednisolone
Benign Mucous Membrane Pemphigoid
About this trial
This is an interventional treatment trial for Benign Mucous Membrane Pemphigoid
Eligibility Criteria
Inclusion Criteria:
patients with age references patients confirmed from dermatology department that they had mucous membrane(MMP) pemphigoid- patients are not allergic o to the drugs being used for the treatment
Exclusion Criteria:
patients below or above age reference used in the study patients with other oral lesions not being confirmed as MMP patients with systemic diseases preventing using of the drugs
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Sites / Locations
- Rehab Fouad Ghouraba
Arms of the Study
Arm 1
Arm 2
Experimental
Experimental
effect of large dose corticosteroids with intra-lestional injection in treatment of MMP
effect of of (MMF), dapsone and cortisone in treatment of MMP
10 patients suffering from MMP were selected referred from dermatology department. These patient were treated using large dose of prednisone 60mg daily plus intra-lesion injection of Triamcinolone Acetonide every week until no further improvement of the lesion occurred (stage I)
10 patients suffering from MMP were selected referred from dermatology department. These patient were treated using large dose of prednisone 60mg daily plus intra-lesion injection of Triamcinolone Acetonide every week until no further improvement of the lesion occurred (stage I) then the prednisolone is withdrawn gradually and substituted with using 1 g of MMF plus 50 mg dapsone till the lowest dose of prednisone could be reached (stage II).