Comparison Between Unihemispheric and Bihemispheric TCDS in Subacute Ischemic Stroke Patients
Stroke, Ischemic, Stroke, Acute, Stroke, Lacunar
About this trial
This is an interventional treatment trial for Stroke, Ischemic
Eligibility Criteria
Inclusion Criteria:
- Those patients had stroke in the last 3 months.
- Maximum with NIH stroke score less than 25.
Exclusion Criteria:
- Patient with second onset of stroke or history of Transient ischemic attack (TIA)
- Metallic Implant or heart pacemakers.
- Primary cerebral or subarachnoid hemorrhagic stroke.
- Seizure or epilepsy or history of epilepsy at the family.
- Intracranial abscess or brain tumor.
- Cardiovascular disease myocardial infarction, heart failure (unstable cardiac status).
- Atrial Fibrillation or paroxysmal AF in the last 30 days.
- Congenital heart diseases.
- Presence of any other neurological or psychiatric disorder.
- Cognitive/consciousness disorders.
- Oher conditions should be excluded (e.g. tumor, cancer, rheumatologic, Lung disease related to infection, renal/ hepatic diseases, deep venous thrombosis and autoimmune diseases).
- Speech disorders (Dysarthria & Aphasia).
- NIH Stroke score above 25, will be excluded.
- Patients who underwent thrombolytic therapy or any vascular interventions.
Sites / Locations
- Ethics Committee - Alexandria Faculty of Medicine
Arms of the Study
Arm 1
Arm 2
Arm 3
Experimental
Experimental
Sham Comparator
Bihemispheric Stimulation Group
Unihemispheric Stimulation Group
Sham Group
The first group tDCS bihemispheric stimulation consisted of 20 minutes of 2 mA direct current with the anode placed over the ipsilesional and the cathode over the contralesional motor cortex M1 (C3 and C4 of the international 10 -20 EEG electrode system).
The second group unilateral stimulation, the anode placed over the ipsilesional motor cortex M1 (C3 or C4 of the international 10 -20 EEG electrode system) and the cathode over contralesional supraorbital bone.
The third sham group, the anode placed over the ipsilesional motor cortex M1 (C3 or C4 of the international 10 -20 EEG electrode system) and the cathode over contralesional supraorbital bone, but delivering no current.