Intravascular Ultrasound Guided PCI in STEMI (iSTEMI)
ST Elevation Myocardial Infarction
About this trial
This is an interventional treatment trial for ST Elevation Myocardial Infarction focused on measuring Primary PCI, Coronary angiography, Intravascular ultra sound (IVUS)
Eligibility Criteria
Inclusion Criteria:
- Age ≥18 years
- Acute onset of chest pain with <12 hours duration
- STEMI as characterized by 2 mm ST elevation in 2 or more V1 through V4 leads or presumed new left bundle branch block with minimum of 1 mm concordant ST elevation or 1 mV ST-segment elevation in the limb lead (II, III and aVF, I, aVL) and V4-V6 or ST depression in 2 or more V1 through V4 leads indicating posterior AMI.
Exclusion Criteria (iPOST2):
Pre-PCI TIMI flow 0 or 1 Potential pregnancy Inability to provide informed consent Unwillingness to consent Unavoidable to use thrombectomy Spontaneous coronary artery dissection Time from symptoms onset to PPCI > 12 hours Culprit in bypass graft Other reason for not including the patient
Exclusion Criteria (iSTEMI):
Potential pregnancy Inability to understand information in order to provide informed consent Unwillingness to consent Spontaneous coronary artery dissection Time from symptoms inset to PPCI > 12 hours Culprit in bypass graft Other reason
Sites / Locations
- Heart Center, RigshospitaletRecruiting
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Active Comparator
Experimental
Experimental
Active Comparator
PCI standard
PCI standard + ischemic conditioning
Stent with ultrasound
Stent without ultrasound