Back to results

A Research Study Investigating Semaglutide in People With Early Alzheimer's Disease (EVOKE Plus)

Primary Purpose

Early Alzheimer´s Disease

Status

Active

Phase

Phase 3

Locations

International

Study Type

Interventional

Intervention

Semaglutide

Placebo (semaglutide)

About this trial

This is an interventional treatment trial for Early Alzheimer´s Disease

Eligibility Criteria

55 Years - 85 Years (Adult, Older Adult)All SexesDoes not accept healthy volunteers

Inclusion Criteria:

Male or female, aged 55-85 years (both inclusive) at the time of signing informed consent.
MCI (mild cognitive impairment) or mild dementia of the Alzheimer's type according to the NIA-AA (National Institute of Aging-Alzheimer's Association) 2018 criteria.
CDR (Clinical Dementia Rating) global score of 0.5 and CDR of 0.5 or more in at least one of the three instrumental activities of daily living categories (personal care, home & hobbies, community affairs) Or CDR global score of 1.0
RBANS (Repeatable Battery for the Assessment of Neuropsychological Status) delayed memory index score of below or equal to 85
MMSE (Mini-Mental State Examination) greater than or equal to 22
Amyloid positivity established with either amyloid PET (positron emission tomography), CSF (cerebrospinal fluid) Aβ1-42 or CSF Aβ1-42/Aβ1-40.
If receiving an approved Alzheimer's disease treatment (such as acetylcholinesterase inhibitors, memantine or aducanumab) the dose must have been stable for at least 3 months prior to screening and should not be changed during the trial unless medically necessary.

Exclusion Criteria:

Brain MRI (or CT) scan suggestive of clinically significant structural CNS (central nervous system) disease confirmed by central read (e.g. cerebral large-vessel disease [large vessel (cortical) infarcts greater than10 mm in diameter], prior macro-haemorrhage [greater than1 cm^3], cerebral vascular malformations, cortical hemosiderosis, intracranial aneurism(s), intracranial tumours, changes suggestive of normal pressure hydrocephalus).
Brain MRI (magnetic resonance imaging) (or CT) scan suggestive of strategic infarcts defined as bilateral thalamic lacunar infarcts and singular paramedian thalamic infarcts confirmed by central read.
Evidence of a relevant neurological disorder other than MCI or mild dementia of the Alzheimer's type at screening, including but not limited to Parkinson's disease, Lewy body disease, frontotemporal dementia of any type, Huntington's disease, amyotrophic lateral sclerosis, multiple sclerosis, systemic lupus erythematosus, progressive supranuclear palsy, neurosyphilis, HIV (human immunodeficiency virus), learning disability, intellectual disability, hypoxic cerebral damage, or significant head trauma with loss of consciousness that led to persistent cognitive deficits.
Evidence of a clinically relevant or unstable psychiatric disorder, based on Diagnostic and Statistical Manual of Mental Disorders (DSM-5) criteria, including schizophrenia or other psychotic disorder, or bipolar disorder. A subject with a history of major depression who has not had an episode in the last 24 months before the day of screening and is considered in remission or whose depression is controlled with treatment can be included in the trial per investigator's judgement.

Arms of the Study

Arm 1

Arm 2

Arm Type

Experimental

Placebo Comparator

Arm Label

Oral semaglutide 14 mg

Placebo (semaglutide)

Arm Description

Participants are given oral semaglutide once daily

Participants are given oral placebo once daily

Outcomes

Primary Outcome Measures

Change in the Clinical Dementia Rating - Sum of Boxes (CDR-SB) score

Score on scale (0 to 18) Measures the impact of cognitive decline on daily function using the following six domains commonly affected in Alzheimer's disease: Cognitive domains: memory, orientation, and judgement and problem solving Function domains: community affairs, home and hobbies, and personal care Based on clinical information obtained from the subject and informant, an individual box score ranging from 0 to 3 is determined that represents "none" to "severe" impairment for each of the six domains. The CDR-Sum of Boxes (CDR-SB) score will be derived by adding the individual scores of the six domains at a given time point. The total CDR-SB score ranges from 0 to 18 with higher scores representing greater impairment.

Secondary Outcome Measures

Change in the Alzheimer's Disease Cooperative Study Activities of Daily Living Scale for MCI (ADCS-ADLMCI) score

Score on scale (0 to 53). An interview-based assessment of information provided by the study partner (informant). The total scores based on 18 items on the scale range from 0 to 53 with lower scores representing greater impairment.

Time to progression to dementia (CDR global greater than or equal to 1.0) among subjects with MCI (CDR global equal to 0.5) at baseline

Week(s)

Change in the 13-item Alzheimer's Disease Assessment Scale - Cognitive Subscale (ADAS-Cog-13) score

Score on scale (0 to 85) Measures the severity of cognitive impairment in various domains including memory, language, orientation, praxis and executive function. The total scores on the scale range from 0 to 85 with higher scores representing greater impairment.

Change in the Montreal Cognitive Assessment (MoCA) score

Score on scale (0 to 30) The assessment includes 8 domains of cognitive function with total scores ranging from 0 to 30 and lower scores indicating greater impairment.

Change in the Alzheimer's Disease Composite Score (ADCOMS)

Score on scale (0 to 1.97) The ADCOMS is a composite clinical outcome comprising 4 items from the ADAS-Cog-13, 2 items from the MMSE and all 6 items from the CDR-SB.32 The total scores on the scale range from 0 to 1.97 with higher scores indicating greater impairment.

Change in the Mini-Mental State Examination (MMSE) score

Score on scale (0 to 30) The MMSE measures orientation, attention, memory, language and visuo-spatial function. The total scores on the scale range from 0 to 30 with lower scores indicating greater impairment.

Change in the 10-item Neuropsychiatric Inventory (NPI) score

104 Score on scale (0 to 120) The 10-item scale assesses symptoms including delusions, hallucinations, agitation/aggression, dysphoria, anxiety, euphoria, apathy, disinhibition, irritability/lability and aberrant motor activity. For each domain the frequency (4-point scale) and severity (3-point scale) of symptoms is reported. The score for each domain is calculated by multiplying the frequency and severity score. The total 10-item NPI score is 0 to 120 with higher scores indicating a greater symptomatology.

Time to progression in disease stage based on global CDR score

Week(s)

Number of treatment emergent adverse events (TEAEs)

Number of events

Change in high sensitivity C-reactive protein level

Ratio

Time to first occurrence of major adverse cardiovascular event (MACE) comprising non-fatal myocardial infarction, non-fatal stroke and allcause death

Week(s)

Time to first occurrence of stroke

Weeks

Change in the EQ-5D-5L proxy score

Score The EQ-5D-5L descriptive system comprises mobility, self-care, usual activities, pain/discomfort and anxiety/depression with five response levels each (no problems, slight problems, moderate problems, severe problems, unable to /extreme problems). The EQ-5D-5L proxy version 1 (the study partner is asked to rate how he/she [the proxy] would rate the subject´s health) will be used in this trial.

Extension phase: Change in the CDR-SB score

Extension phase: Change in the ADCS-ADL-MCI score

Score on scale (0 to 53) An interview-based assessment of information provided by the study partner (informant). The total scores based on 18 items on the scale range from 0 to 53 with lower scores representing greater impairment.

Extension phase: Time to progression to dementia (CDR global greater than or equal to 1.0) among subjects with MCI (CDR global equal to 0.5) at baseline

Week(s)

Full Information

NCT ID

NCT04777409

First Posted

February 26, 2021

Last Updated

October 18, 2023

Sponsor

Novo Nordisk A/S

1. Study Identification

Unique Protocol Identification Number

NCT04777409

Brief Title

A Research Study Investigating Semaglutide in People With Early Alzheimer's Disease (EVOKE Plus)

Official Title

A Randomised Double-blind Placebo-controlled Clinical Trial Investigating the Effect and Safety of Oral Semaglutide in Subjects With Early Alzheimer´s Disease (EVOKE Plus)

Study Type

Interventional

2. Study Status

Record Verification Date

October 2023

Overall Recruitment Status

Active, not recruiting

Study Start Date

May 18, 2021 (Actual)

Primary Completion Date

September 19, 2025 (Anticipated)

Study Completion Date

October 23, 2026 (Anticipated)

3. Sponsor/Collaborators

Responsible Party, by Official Title

Sponsor

Name of the Sponsor

Novo Nordisk A/S

4. Oversight

Studies a U.S. FDA-regulated Drug Product

Yes

Studies a U.S. FDA-regulated Device Product

Data Monitoring Committee

Yes

5. Study Description

Brief Summary

This study is done to find out whether the medicine, semaglutide, has a positive effect on early Alzheimer's disease. Participants will either get semaglutide or placebo (a "dummy" medicine which does not contain any study medicine) - which treatment participants get is decided by an equal chance. The study will last for up to 173 weeks (about 3 years and 4 months). Participants will have 17 clinic visits and 1 phone call with the study doctor. The study includes various tests and scans. At 10 of the clinic visits participants will have blood samples taken. Participants must have a study partner, who is willing to take part in the study. Women cannot take part if pregnant, breastfeeding or plan to become pregnant during the study period. A cerebrospinal fluid (CSF) sub-study will be performed as a part of the study. The sub-study will be performed on a selection of sites based on their experience with CSF sampling and willingness to participate in this sub-study. The endpoints related to this sub-study are exploratory only.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study

Early Alzheimer´s Disease

7. Study Design

Primary Purpose

Treatment

Study Phase

Phase 3

Interventional Study Model

Parallel Assignment

Masking

ParticipantCare ProviderInvestigatorOutcomes Assessor

Masking Description

Sponsor staff involved in the clinical trial is masked according to company standard procedures.

Allocation

Randomized

Enrollment

1840 (Anticipated)

8. Arms, Groups, and Interventions

Arm Title

Oral semaglutide 14 mg

Arm Type

Experimental

Arm Description

Participants are given oral semaglutide once daily

Arm Title

Placebo (semaglutide)

Arm Type

Placebo Comparator

Arm Description

Participants are given oral placebo once daily

Intervention Type

Drug

Intervention Name(s)

Semaglutide

Intervention Description

Oral semaglutide once-daily, dose gradually increased to 14 mg. The study will last for up to 173 weeks

Intervention Type

Drug

Intervention Name(s)

Placebo (semaglutide)

Intervention Description

Oral placebo (semaglutide) once-daily. The study will last for up to 173 weeks

Primary Outcome Measure Information:

Title

Change in the Clinical Dementia Rating - Sum of Boxes (CDR-SB) score

Description

Time Frame

From baseline (week 0) to week 104

Secondary Outcome Measure Information:

Title

Change in the Alzheimer's Disease Cooperative Study Activities of Daily Living Scale for MCI (ADCS-ADLMCI) score

Description

Time Frame

From baseline (week 0) to week 104

Title

Time to progression to dementia (CDR global greater than or equal to 1.0) among subjects with MCI (CDR global equal to 0.5) at baseline

Description

Week(s)

Time Frame

From baseline (week 0) to week 104

Title

Change in the 13-item Alzheimer's Disease Assessment Scale - Cognitive Subscale (ADAS-Cog-13) score

Description

Time Frame

From baseline (week 0) to week 104

Title

Change in the Montreal Cognitive Assessment (MoCA) score

Description

Score on scale (0 to 30) The assessment includes 8 domains of cognitive function with total scores ranging from 0 to 30 and lower scores indicating greater impairment.

Time Frame

From baseline (week 0) to week 104

Title

Change in the Alzheimer's Disease Composite Score (ADCOMS)

Description

Time Frame

From baseline (week 0) to week 104

Title

Change in the Mini-Mental State Examination (MMSE) score

Description

Time Frame

From baseline (week 0) to week 104

Title

Change in the 10-item Neuropsychiatric Inventory (NPI) score

Description

Time Frame

From baseline (week 0) to week 104

Title

Time to progression in disease stage based on global CDR score

Description

Week(s)

Time Frame

From baseline (week 0) to week 104

Title

Number of treatment emergent adverse events (TEAEs)

Description

Number of events

Time Frame

From baseline (week 0) to week 104

Title

Change in high sensitivity C-reactive protein level

Description

Ratio

Time Frame

From baseline (week 0) to week 104

Title

Time to first occurrence of major adverse cardiovascular event (MACE) comprising non-fatal myocardial infarction, non-fatal stroke and allcause death

Description

Week(s)

Time Frame

From baseline (week 0) to week 104

Title

Time to first occurrence of stroke

Description

Weeks

Time Frame

From baseline (week 0) to week 104

Title

Change in the EQ-5D-5L proxy score

Description

Time Frame

From baseline (week 0) to week 104

Title

Extension phase: Change in the CDR-SB score

Description

Time Frame

From baseline (week 0) to week 156

Title

Extension phase: Change in the ADCS-ADL-MCI score

Description

Time Frame

From baseline (week 0) to week 156

Title

Extension phase: Time to progression to dementia (CDR global greater than or equal to 1.0) among subjects with MCI (CDR global equal to 0.5) at baseline

Description

Week(s)

Time Frame

From baseline (week 0) to week 156

10. Eligibility

Sex

All

Minimum Age & Unit of Time

55 Years

Maximum Age & Unit of Time

85 Years

Accepts Healthy Volunteers

Eligibility Criteria

Inclusion Criteria: Male or female, aged 55-85 years (both inclusive) at the time of signing informed consent. MCI (mild cognitive impairment) or mild dementia of the Alzheimer's type according to the NIA-AA (National Institute of Aging-Alzheimer's Association) 2018 criteria. CDR (Clinical Dementia Rating) global score of 0.5 and CDR of 0.5 or more in at least one of the three instrumental activities of daily living categories (personal care, home & hobbies, community affairs) Or CDR global score of 1.0 RBANS (Repeatable Battery for the Assessment of Neuropsychological Status) delayed memory index score of below or equal to 85 MMSE (Mini-Mental State Examination) greater than or equal to 22 Amyloid positivity established with either amyloid PET (positron emission tomography), CSF (cerebrospinal fluid) Aβ1-42 or CSF Aβ1-42/Aβ1-40. If receiving an approved Alzheimer's disease treatment (such as acetylcholinesterase inhibitors, memantine or aducanumab) the dose must have been stable for at least 3 months prior to screening and should not be changed during the trial unless medically necessary. Exclusion Criteria: Brain MRI (or CT) scan suggestive of clinically significant structural CNS (central nervous system) disease confirmed by central read (e.g. cerebral large-vessel disease [large vessel (cortical) infarcts greater than10 mm in diameter], prior macro-haemorrhage [greater than1 cm^3], cerebral vascular malformations, cortical hemosiderosis, intracranial aneurism(s), intracranial tumours, changes suggestive of normal pressure hydrocephalus). Brain MRI (magnetic resonance imaging) (or CT) scan suggestive of strategic infarcts defined as bilateral thalamic lacunar infarcts and singular paramedian thalamic infarcts confirmed by central read. Evidence of a relevant neurological disorder other than MCI or mild dementia of the Alzheimer's type at screening, including but not limited to Parkinson's disease, Lewy body disease, frontotemporal dementia of any type, Huntington's disease, amyotrophic lateral sclerosis, multiple sclerosis, systemic lupus erythematosus, progressive supranuclear palsy, neurosyphilis, HIV (human immunodeficiency virus), learning disability, intellectual disability, hypoxic cerebral damage, or significant head trauma with loss of consciousness that led to persistent cognitive deficits. Evidence of a clinically relevant or unstable psychiatric disorder, based on Diagnostic and Statistical Manual of Mental Disorders (DSM-5) criteria, including schizophrenia or other psychotic disorder, or bipolar disorder. A subject with a history of major depression who has not had an episode in the last 24 months before the day of screening and is considered in remission or whose depression is controlled with treatment can be included in the trial per investigator's judgement.

Overall Study Officials:

First Name & Middle Initial & Last Name & Degree

Clinical Transparency (dept. 2834)

Organizational Affiliation

Novo Nordisk A/S

Official's Role

Study Director

Facility Information:

Facility Name

Novo Nordisk Investigational Site

City

Phoenix

State/Province

Arizona

ZIP/Postal Code

85006

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Sun City

State/Province

Arizona

ZIP/Postal Code

85351

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Anaheim

State/Province

California

ZIP/Postal Code

92805

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Lomita

State/Province

California

ZIP/Postal Code

90717

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Long Beach

State/Province

California

ZIP/Postal Code

90807

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Los Angeles

State/Province

California

ZIP/Postal Code

90048

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Los Angeles

State/Province

California

ZIP/Postal Code

90095

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Newport Beach

State/Province

California

ZIP/Postal Code

92660

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Panorama City

State/Province

California

ZIP/Postal Code

91402

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Pasadena

State/Province

California

ZIP/Postal Code

90048

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

San Diego

State/Province

California

ZIP/Postal Code

92123

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Santa Ana

State/Province

California

ZIP/Postal Code

92705

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Sherman Oaks

State/Province

California

ZIP/Postal Code

91403

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Basalt

State/Province

Colorado

ZIP/Postal Code

81621

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Denver

State/Province

Colorado

ZIP/Postal Code

80210

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Denver

State/Province

Colorado

ZIP/Postal Code

80218

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Danbury

State/Province

Connecticut

ZIP/Postal Code

06810

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Fairfield

State/Province

Connecticut

ZIP/Postal Code

06824

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Norwalk

State/Province

Connecticut

ZIP/Postal Code

06851

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Apopka

State/Province

Florida

ZIP/Postal Code

32703

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Atlantis

State/Province

Florida

ZIP/Postal Code

33462

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Aventura

State/Province

Florida

ZIP/Postal Code

33180

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Delray Beach

State/Province

Florida

ZIP/Postal Code

33445

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Doral

State/Province

Florida

ZIP/Postal Code

33122

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Fort Myers

State/Province

Florida

ZIP/Postal Code

33912

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Greenacres City

State/Province

Florida

ZIP/Postal Code

33467

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Hialeah

State/Province

Florida

ZIP/Postal Code

33012

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Hialeah

State/Province

Florida

ZIP/Postal Code

33016

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Lady Lake

State/Province

Florida

ZIP/Postal Code

32159

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Maitland

State/Province

Florida

ZIP/Postal Code

32751

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Miami

State/Province

Florida

ZIP/Postal Code

33015

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Miami

State/Province

Florida

ZIP/Postal Code

33122

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Miami

State/Province

Florida

ZIP/Postal Code

33125

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Miami

State/Province

Florida

ZIP/Postal Code

33173

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Miami

State/Province

Florida

ZIP/Postal Code

33176

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Naples

State/Province

Florida

ZIP/Postal Code

34105

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

New Port Richey

State/Province

Florida

ZIP/Postal Code

34652

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Ocoee

State/Province

Florida

ZIP/Postal Code

34761

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Orlando

State/Province

Florida

ZIP/Postal Code

32807

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Orlando

State/Province

Florida

ZIP/Postal Code

32819

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Palm Beach Gardens

State/Province

Florida

ZIP/Postal Code

33410

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Sarasota

State/Province

Florida

ZIP/Postal Code

34239

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Sarasota

State/Province

Florida

ZIP/Postal Code

34243

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Stuart

State/Province

Florida

ZIP/Postal Code

34997

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Tampa

State/Province

Florida

ZIP/Postal Code

33609

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Tampa

State/Province

Florida

ZIP/Postal Code

33613

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

West Palm Beach

State/Province

Florida

ZIP/Postal Code

33407

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Winter Park

State/Province

Florida

ZIP/Postal Code

32789

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Decatur

State/Province

Georgia

ZIP/Postal Code

30030

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Honolulu

State/Province

Hawaii

ZIP/Postal Code

96817

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Meridian

State/Province

Idaho

ZIP/Postal Code

83642

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Indianapolis

State/Province

Indiana

ZIP/Postal Code

46256

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Topeka

State/Province

Kansas

ZIP/Postal Code

66606

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Lexington

State/Province

Kentucky

ZIP/Postal Code

40504

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Bangor

State/Province

Maine

ZIP/Postal Code

04401

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Methuen

State/Province

Massachusetts

ZIP/Postal Code

01844

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Paw Paw

State/Province

Michigan

ZIP/Postal Code

49079

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Saint Paul

State/Province

Minnesota

ZIP/Postal Code

55130

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Hattiesburg

State/Province

Mississippi

ZIP/Postal Code

39401

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Las Vegas

State/Province

Nevada

ZIP/Postal Code

89106

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Toms River

State/Province

New Jersey

ZIP/Postal Code

08755

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

West Long Branch

State/Province

New Jersey

ZIP/Postal Code

07764

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Lake Success

State/Province

New York

ZIP/Postal Code

11042

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Manhasset

State/Province

New York

ZIP/Postal Code

11030

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

New York

State/Province

New York

ZIP/Postal Code

10016

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Staten Island

State/Province

New York

ZIP/Postal Code

10314

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Syracuse

State/Province

New York

ZIP/Postal Code

13210

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Charlotte

State/Province

North Carolina

ZIP/Postal Code

28211

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Matthews

State/Province

North Carolina

ZIP/Postal Code

28105

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Beachwood

State/Province

Ohio

ZIP/Postal Code

44122

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Canton

State/Province

Ohio

ZIP/Postal Code

44718

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Centerville

State/Province

Ohio

ZIP/Postal Code

45459

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Lakewood

State/Province

Ohio

ZIP/Postal Code

44107

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Tulsa

State/Province

Oklahoma

ZIP/Postal Code

74136

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Portland

State/Province

Oregon

ZIP/Postal Code

97210

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Portland

State/Province

Oregon

ZIP/Postal Code

97225

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Jenkintown

State/Province

Pennsylvania

ZIP/Postal Code

19046

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Media

State/Province

Pennsylvania

ZIP/Postal Code

19063

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Port Royal

State/Province

South Carolina

ZIP/Postal Code

29935

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Summerville

State/Province

South Carolina

ZIP/Postal Code

29485

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Knoxville

State/Province

Tennessee

ZIP/Postal Code

37909

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Nashville

State/Province

Tennessee

ZIP/Postal Code

37212

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Austin

State/Province

Texas

ZIP/Postal Code

78749

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Dallas

State/Province

Texas

ZIP/Postal Code

75243

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Houston

State/Province

Texas

ZIP/Postal Code

77030

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Houston

State/Province

Texas

ZIP/Postal Code

77054

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Katy

State/Province

Texas

ZIP/Postal Code

77450

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

San Antonio

State/Province

Texas

ZIP/Postal Code

78229

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Sugar Land

State/Province

Texas

ZIP/Postal Code

77478

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Bennington

State/Province

Vermont

ZIP/Postal Code

05201

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Falls Church

State/Province

Virginia

ZIP/Postal Code

22043

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Kirkland

State/Province

Washington

ZIP/Postal Code

98034

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Seattle

State/Province

Washington

ZIP/Postal Code

98104

Country

United States

Facility Name

Novo Nordisk Investigational Site

City

Buenos Aires

ZIP/Postal Code

C1012AAR

Country

Argentina

Facility Name

Novo Nordisk Investigational Site

City

Buenos Aires

ZIP/Postal Code

C1181ACH

Country

Argentina

Facility Name

Novo Nordisk Investigational Site

City

Caba

ZIP/Postal Code

1405

Country

Argentina

Facility Name

Novo Nordisk Investigational Site

City

Caba

ZIP/Postal Code

1427

Country

Argentina

Facility Name

Novo Nordisk Investigational Site

City

Caba

ZIP/Postal Code

1428

Country

Argentina

Facility Name

Novo Nordisk Investigational Site

City

Córdoba

ZIP/Postal Code

X5004AOA

Country

Argentina

Facility Name

Novo Nordisk Investigational Site

City

Mendoza

ZIP/Postal Code

5500

Country

Argentina

Facility Name

Novo Nordisk Investigational Site

City

Darlinghurst

State/Province

New South Wales

ZIP/Postal Code

2010

Country

Australia

Facility Name

Novo Nordisk Investigational Site

City

Kogarah

State/Province

New South Wales

ZIP/Postal Code

2217

Country

Australia

Facility Name

Novo Nordisk Investigational Site

City

Macquarie Park

State/Province

New South Wales

ZIP/Postal Code

2113

Country

Australia

Facility Name

Novo Nordisk Investigational Site

City

Waratah

State/Province

New South Wales

ZIP/Postal Code

2298

Country

Australia

Facility Name

Novo Nordisk Investigational Site

City

Chermside

State/Province

Queensland

ZIP/Postal Code

4032

Country

Australia

Facility Name

Novo Nordisk Investigational Site

City

Ivanhoe

State/Province

Victoria

ZIP/Postal Code

3079

Country

Australia

Facility Name

Novo Nordisk Investigational Site

City

Malvern

State/Province

Victoria

ZIP/Postal Code

3144

Country

Australia

Facility Name

Novo Nordisk Investigational Site

City

Nedlands

State/Province

Western Australia

ZIP/Postal Code

6009

Country

Australia

Facility Name

Novo Nordisk Investigational Site

City

Innsbruck

ZIP/Postal Code

6020

Country

Austria

Facility Name

Novo Nordisk Investigational Site

City

Salzburg

ZIP/Postal Code

5020

Country

Austria

Facility Name

Novo Nordisk Investigational Site

City

Wien

ZIP/Postal Code

1090

Country

Austria

Facility Name

Novo Nordisk Investigational Site

City

Edegem

ZIP/Postal Code

2650

Country

Belgium

Facility Name

Novo Nordisk Investigational Site

City

Gent

ZIP/Postal Code

9000

Country

Belgium

Facility Name

Novo Nordisk Investigational Site

City

Kortrijk

ZIP/Postal Code

8500

Country

Belgium

Facility Name

Novo Nordisk Investigational Site

City

Leuven

ZIP/Postal Code

3000

Country

Belgium

Facility Name

Novo Nordisk Investigational Site

City

Liège

ZIP/Postal Code

4000

Country

Belgium

Facility Name

Novo Nordisk Investigational Site

City

Brasília

State/Province

Distrito Federal

ZIP/Postal Code

70200730

Country

Brazil

Facility Name

Novo Nordisk Investigational Site

City

Belo Horizonte

State/Province

Minas Gerais

ZIP/Postal Code

30130-100

Country

Brazil

Facility Name

Novo Nordisk Investigational Site

City

Curitiba

State/Province

Parana

ZIP/Postal Code

81210-310

Country

Brazil

Facility Name

Novo Nordisk Investigational Site

City

Maringa

State/Province

Parana

ZIP/Postal Code

87013-250

Country

Brazil

Facility Name

Novo Nordisk Investigational Site

City

Porto Alegre

State/Province

Rio Grande Do Sul

ZIP/Postal Code

90430-001

Country

Brazil

Facility Name

Novo Nordisk Investigational Site

City

São Paulo

State/Province

Sao Paulo

ZIP/Postal Code

01228-000

Country

Brazil

Facility Name

Novo Nordisk Investigational Site

City

São Paulo

State/Province

Sao Paulo

ZIP/Postal Code

04024-000

Country

Brazil

Facility Name

Novo Nordisk Investigational Site

City

São Paulo

State/Province

Sao Paulo

ZIP/Postal Code

05003-090

Country

Brazil

Facility Name

Novo Nordisk Investigational Site

City

Rio de Janeiro

ZIP/Postal Code

22270-060

Country

Brazil

Facility Name

Novo Nordisk Investigational Site

City

Sofia

ZIP/Postal Code

1113

Country

Bulgaria

Facility Name

Novo Nordisk Investigational Site

City

Sofia

ZIP/Postal Code

1408

Country

Bulgaria

Facility Name

Novo Nordisk Investigational Site

City

Sofia

ZIP/Postal Code

1431

Country

Bulgaria

Facility Name

Novo Nordisk Investigational Site

City

Sofia

ZIP/Postal Code

1606

Country

Bulgaria

Facility Name

Novo Nordisk Investigational Site

City

Kelowna

State/Province

British Columbia

ZIP/Postal Code

V1Y 1Z9

Country

Canada

Facility Name

Novo Nordisk Investigational Site

City

Penticton

State/Province

British Columbia

ZIP/Postal Code

V2A 5L5

Country

Canada

Facility Name

Novo Nordisk Investigational Site

City

Victoria

State/Province

British Columbia

ZIP/Postal Code

V8R 1J8

Country

Canada

Facility Name

Novo Nordisk Investigational Site

City

West Vancouver

State/Province

British Columbia

ZIP/Postal Code

V7T 1C5

Country

Canada

Facility Name

Novo Nordisk Investigational Site

City

Halifax

State/Province

Nova Scotia

ZIP/Postal Code

B3S 1N2

Country

Canada

Facility Name

Novo Nordisk Investigational Site

City

New Minas

State/Province

Nova Scotia

ZIP/Postal Code

B4N 3R7

Country

Canada

Facility Name

Novo Nordisk Investigational Site

City

Ottawa

State/Province

Ontario

ZIP/Postal Code

K1Z 1G3

Country

Canada

Facility Name

Novo Nordisk Investigational Site

City

Peterborough

State/Province

Ontario

ZIP/Postal Code

K9H2P4

Country

Canada

Facility Name

Novo Nordisk Investigational Site

City

Toronto

State/Province

Ontario

ZIP/Postal Code

M3B2S7

Country

Canada

Facility Name

Novo Nordisk Investigational Site

City

Toronto

State/Province

Ontario

ZIP/Postal Code

M4G 3E8

Country

Canada

Facility Name

Novo Nordisk Investigational Site

City

Toronto

State/Province

Ontario

ZIP/Postal Code

M4N 3M5

Country

Canada

Facility Name

Novo Nordisk Investigational Site

City

Toronto

State/Province

Ontario

ZIP/Postal Code

M5B 1X1

Country

Canada

Facility Name

Novo Nordisk Investigational Site

City

Toronto

State/Province

Ontario

ZIP/Postal Code

M5T 2S8

Country

Canada

Facility Name

Novo Nordisk Investigational Site

City

Gatineau

State/Province

Quebec

ZIP/Postal Code

J8T 8J1

Country

Canada

Facility Name

Novo Nordisk Investigational Site

City

Greenfield-Park

State/Province

Quebec

ZIP/Postal Code

J4V 2J2

Country

Canada

Facility Name

Novo Nordisk Investigational Site

City

Montréal

State/Province

Quebec

ZIP/Postal Code

H4H 1R3

Country

Canada

Facility Name

Novo Nordisk Investigational Site

City

Québec

State/Province

Quebec

ZIP/Postal Code

G1J 1Z4

Country

Canada

Facility Name

Novo Nordisk Investigational Site

City

Sherbrooke

State/Province

Quebec

ZIP/Postal Code

J1L 0H8

Country

Canada

Facility Name

Novo Nordisk Investigational Site

City

Beijing

State/Province

Beijing

ZIP/Postal Code

100020

Country

China

Facility Name

Novo Nordisk Investigational Site

City

Beijing

State/Province

Beijing

ZIP/Postal Code

100050

Country

China

Facility Name

Novo Nordisk Investigational Site

City

Beijing

State/Province

Beijing

ZIP/Postal Code

100053

Country

China

Facility Name

Novo Nordisk Investigational Site

City

Beijing

State/Province

Beijing

ZIP/Postal Code

100070

Country

China

Facility Name

Novo Nordisk Investigational Site

City

Beijing

State/Province

Beijing

ZIP/Postal Code

100088

Country

China

Facility Name

Novo Nordisk Investigational Site

City

Beijing

State/Province

Beijing

ZIP/Postal Code

100089

Country

China

Facility Name

Novo Nordisk Investigational Site

City

Beijing

State/Province

Beijing

ZIP/Postal Code

100096

Country

China

Facility Name

Novo Nordisk Investigational Site

City

Beijing

State/Province

Beijing

ZIP/Postal Code

100730

Country

China

Facility Name

Novo Nordisk Investigational Site

City

Chongqing

State/Province

Chongqing

ZIP/Postal Code

400016

Country

China

Facility Name

Novo Nordisk Investigational Site

City

Fuzhou

State/Province

Fujian

ZIP/Postal Code

350001

Country

China

Facility Name

Novo Nordisk Investigational Site

City

Guangzhou

State/Province

Guangdong

ZIP/Postal Code

510120

Country

China

Facility Name

Novo Nordisk Investigational Site

City

Guangzhou

State/Province

Guangdong

ZIP/Postal Code

510180

Country

China

Facility Name

Novo Nordisk Investigational Site

City

Guangzhou

State/Province

Guangdong

ZIP/Postal Code

510260

Country

China

Facility Name

Novo Nordisk Investigational Site

City

Guangzhou

State/Province

Guangdong

ZIP/Postal Code

510370

Country

China

Facility Name

Novo Nordisk Investigational Site

City

Zhengzhou

State/Province

Henan

ZIP/Postal Code

450003

Country

China

Facility Name

Novo Nordisk Investigational Site

City

Changsha

State/Province

Hunan

ZIP/Postal Code

410008

Country

China

Facility Name

Novo Nordisk Investigational Site

City

Baotou

State/Province

Inner Mongolia

ZIP/Postal Code

014010

Country

China

Facility Name

Novo Nordisk Investigational Site

City

Nanjing

State/Province

Jiangsu

ZIP/Postal Code

210000

Country

China

Facility Name

Novo Nordisk Investigational Site

City

Nanjing

State/Province

Jiangsu

ZIP/Postal Code

210008

Country

China

Facility Name

Novo Nordisk Investigational Site

City

Nanjing

State/Province

Jiangsu

ZIP/Postal Code

210009

Country

China

Facility Name

Novo Nordisk Investigational Site

City

Wuxi

State/Province

Jiangsu

ZIP/Postal Code

Psychiatry

Country

China

Facility Name

Novo Nordisk Investigational Site

City

Yangzhou

State/Province

Jiangsu

ZIP/Postal Code

225001

Country

China

Facility Name

Novo Nordisk Investigational Site

City

Nanchang

State/Province

Jiangxi

ZIP/Postal Code

330006

Country

China

Facility Name

Novo Nordisk Investigational Site

City

Changchun

State/Province

Jilin

ZIP/Postal Code

130031

Country

China

Facility Name

Novo Nordisk Investigational Site

City

Xining

State/Province

Qinghai

ZIP/Postal Code

810007

Country

China

Facility Name

Novo Nordisk Investigational Site

City

Shanghai

State/Province

Shanghai

ZIP/Postal Code

200040

Country

China

Facility Name

Novo Nordisk Investigational Site

City

Shanghai

State/Province

Shanghai

ZIP/Postal Code

200123

Country

China

Facility Name

Novo Nordisk Investigational Site

City

Shanghai

State/Province

Shanghai

ZIP/Postal Code

200233

Country

China

Facility Name

Novo Nordisk Investigational Site

City

Chengdu

State/Province

Sichuan

ZIP/Postal Code

610041

Country

China

Facility Name

Novo Nordisk Investigational Site

City

Tianjin

State/Province

Tianjin

ZIP/Postal Code

300052

Country

China

Facility Name

Novo Nordisk Investigational Site

City

Tianjin

State/Province

Tianjin

ZIP/Postal Code

300350

Country

China

Facility Name

Novo Nordisk Investigational Site

City

Hangzhou

State/Province

Zhejiang

ZIP/Postal Code

310003

Country

China

Facility Name

Novo Nordisk Investigational Site

City

Zagreb

State/Province

Grad Zagreb

ZIP/Postal Code

10000

Country

Croatia

Facility Name

Novo Nordisk Investigational Site

City

Zagreb

ZIP/Postal Code

10000

Country

Croatia

Facility Name

Novo Nordisk Investigational Site

City

Brno-Lisen

ZIP/Postal Code

628 00

Country

Czechia

Facility Name

Novo Nordisk Investigational Site

City

Chocen

ZIP/Postal Code

565 01

Country

Czechia

Facility Name

Novo Nordisk Investigational Site

City

Olomouc

ZIP/Postal Code

77900

Country

Czechia

Facility Name

Novo Nordisk Investigational Site

City

Praha 10

ZIP/Postal Code

109 00

Country

Czechia

Facility Name

Novo Nordisk Investigational Site

City

Praha 6 Dejvice

ZIP/Postal Code

16000

Country

Czechia

Facility Name

Novo Nordisk Investigational Site

City

Rychnov nad Kneznou

ZIP/Postal Code

51601

Country

Czechia

Facility Name

Novo Nordisk Investigational Site

City

Aarhus N

ZIP/Postal Code

8200

Country

Denmark

Facility Name

Novo Nordisk Investigational Site

City

København Ø

ZIP/Postal Code

2100

Country

Denmark

Facility Name

Novo Nordisk Investigational Site

City

Roskilde

ZIP/Postal Code

4000

Country

Denmark

Facility Name

Novo Nordisk Investigational Site

City

Helsinki

ZIP/Postal Code

00180

Country

Finland

Facility Name

Novo Nordisk Investigational Site

City

Kuopio

ZIP/Postal Code

70210

Country

Finland

Facility Name

Novo Nordisk Investigational Site

City

Turku

ZIP/Postal Code

20520

Country

Finland

Facility Name

Novo Nordisk Investigational Site

City

Bordeaux

ZIP/Postal Code

33000

Country

France

Facility Name

Novo Nordisk Investigational Site

City

Bron

ZIP/Postal Code

69500

Country

France

Facility Name

Novo Nordisk Investigational Site

City

Dijon

ZIP/Postal Code

21000

Country

France

Facility Name

Novo Nordisk Investigational Site

City

Marseille

ZIP/Postal Code

13005

Country

France

Facility Name

Novo Nordisk Investigational Site

City

Nice

ZIP/Postal Code

06100

Country

France

Facility Name

Novo Nordisk Investigational Site

City

Paris

ZIP/Postal Code

75010

Country

France

Facility Name

Novo Nordisk Investigational Site

City

Paris

ZIP/Postal Code

75013

Country

France

Facility Name

Novo Nordisk Investigational Site

City

Reims cedex

ZIP/Postal Code

51092

Country

France

Facility Name

Novo Nordisk Investigational Site

City

Saint Herblain

ZIP/Postal Code

44800

Country

France

Facility Name

Novo Nordisk Investigational Site

City

Strasbourg cedex 2

ZIP/Postal Code

67098

Country

France

Facility Name

Novo Nordisk Investigational Site

City

Toulouse

ZIP/Postal Code

31300

Country

France

Facility Name

Novo Nordisk Investigational Site

City

Villeurbanne

ZIP/Postal Code

69100

Country

France

Facility Name

Novo Nordisk Investigational Site

City

Köln

ZIP/Postal Code

50937

Country

Germany

Facility Name

Novo Nordisk Investigational Site

City

Münster

ZIP/Postal Code

48149

Country

Germany

Facility Name

Novo Nordisk Investigational Site

City

Athens

ZIP/Postal Code

GR-11521

Country

Greece

Facility Name

Novo Nordisk Investigational Site

City

Athens

ZIP/Postal Code

GR-11526

Country

Greece

Facility Name

Novo Nordisk Investigational Site

City

Athens

ZIP/Postal Code

GR-11528

Country

Greece

Facility Name

Novo Nordisk Investigational Site

City

Athens

ZIP/Postal Code

GR-15123

Country

Greece

Facility Name

Novo Nordisk Investigational Site

City

Chaidari, Athens

ZIP/Postal Code

GR-12462

Country

Greece

Facility Name

Novo Nordisk Investigational Site

City

Marousi

ZIP/Postal Code

GR-15125

Country

Greece

Facility Name

Novo Nordisk Investigational Site

City

Thessaloniki

ZIP/Postal Code

GR-54643

Country

Greece

Facility Name

Novo Nordisk Investigational Site

City

Thessaloniki

ZIP/Postal Code

GR54636

Country

Greece

Facility Name

Novo Nordisk Investigational Site

City

Budapest

ZIP/Postal Code

1033

Country

Hungary

Facility Name

Novo Nordisk Investigational Site

City

Budapest

ZIP/Postal Code

H-1083

Country

Hungary

Facility Name

Novo Nordisk Investigational Site

City

Debrecen

ZIP/Postal Code

4032

Country

Hungary

Facility Name

Novo Nordisk Investigational Site

City

Gyor

ZIP/Postal Code

9024

Country

Hungary

Facility Name

Novo Nordisk Investigational Site

City

Gyöngyös

ZIP/Postal Code

3200

Country

Hungary

Facility Name

Novo Nordisk Investigational Site

City

Kalocsa

ZIP/Postal Code

H-6300

Country

Hungary

Facility Name

Novo Nordisk Investigational Site

City

Kaposvár

ZIP/Postal Code

H-7400

Country

Hungary

Facility Name

Novo Nordisk Investigational Site

City

Pécs

ZIP/Postal Code

H-7633

Country

Hungary

Facility Name

Novo Nordisk Investigational Site

City

Zalaegerszeg

ZIP/Postal Code

8900

Country

Hungary

Facility Name

Novo Nordisk Investigational Site

City

Dublin

ZIP/Postal Code

D04 VH51

Country

Ireland

Facility Name

Novo Nordisk Investigational Site

City

Dublin

ZIP/Postal Code

D08 NHY1

Country

Ireland

Facility Name

Novo Nordisk Investigational Site

City

Dublin

ZIP/Postal Code

D24 NR0A

Country

Ireland

Facility Name

Novo Nordisk Investigational Site

City

Haifa

ZIP/Postal Code

3109601

Country

Israel

Facility Name

Novo Nordisk Investigational Site

City

Petach Tikva

ZIP/Postal Code

49100

Country

Israel

Facility Name

Novo Nordisk Investigational Site

City

Tel Aviv

ZIP/Postal Code

6423906

Country

Israel

Facility Name

Novo Nordisk Investigational Site

City

Tel Hashomer, Ramat Gan

ZIP/Postal Code

5262000

Country

Israel

Facility Name

Novo Nordisk Investigational Site

City

Ancona

ZIP/Postal Code

60126

Country

Italy

Facility Name

Novo Nordisk Investigational Site

City

Brescia

ZIP/Postal Code

25123

Country

Italy

Facility Name

Novo Nordisk Investigational Site

City

Chieti

ZIP/Postal Code

66100

Country

Italy

Facility Name

Novo Nordisk Investigational Site

City

Firenze

ZIP/Postal Code

50134

Country

Italy

Facility Name

Novo Nordisk Investigational Site

City

Milano

ZIP/Postal Code

20122

Country

Italy

Facility Name

Novo Nordisk Investigational Site

City

Milano

ZIP/Postal Code

20132

Country

Italy

Facility Name

Novo Nordisk Investigational Site

City

Monza

ZIP/Postal Code

20900

Country

Italy

Facility Name

Novo Nordisk Investigational Site

City

Perugia

ZIP/Postal Code

06129

Country

Italy

Facility Name

Novo Nordisk Investigational Site

City

Roma

ZIP/Postal Code

00128

Country

Italy

Facility Name

Novo Nordisk Investigational Site

City

Roma

ZIP/Postal Code

00133

Country

Italy

Facility Name

Novo Nordisk Investigational Site

City

Roma

ZIP/Postal Code

00168

Country

Italy

Facility Name

Novo Nordisk Investigational Site

City

Roma

ZIP/Postal Code

00179

Country

Italy

Facility Name

Novo Nordisk Investigational Site

City

Torino

ZIP/Postal Code

10126

Country

Italy

Facility Name

Novo Nordisk Investigational Site

City

Anan, Tokushima

ZIP/Postal Code

774-0014

Country

Japan

Facility Name

Novo Nordisk Investigational Site

City

Anjo-shi, Aichi

ZIP/Postal Code

446-8510

Country

Japan

Facility Name

Novo Nordisk Investigational Site

City

Arakawa-ku,Tokyo

ZIP/Postal Code

116-0014

Country

Japan

Facility Name

Novo Nordisk Investigational Site

City

Bunkyo-ku, Tokyo

ZIP/Postal Code

113-0034

Country

Japan

Facility Name

Novo Nordisk Investigational Site

City

Bunkyo-ku,Tokyo

ZIP/Postal Code

113-8519

Country

Japan

Facility Name

Novo Nordisk Investigational Site

City

Chib-shi, Chiba

ZIP/Postal Code

260-8656

Country

Japan

Facility Name

Novo Nordisk Investigational Site

City

Chofu-shi,Tokyo

ZIP/Postal Code

182-0036

Country

Japan

Facility Name

Novo Nordisk Investigational Site

City

Fujioka-Shi, Gunma

ZIP/Postal Code

375-0017

Country

Japan

Facility Name

Novo Nordisk Investigational Site

City

Hachioji-shi, Tokyo

ZIP/Postal Code

192-0071

Country

Japan

Facility Name

Novo Nordisk Investigational Site

City

Hamamatsu-shi, Shizuoka

ZIP/Postal Code

434-8511

Country

Japan

Facility Name

Novo Nordisk Investigational Site

City

Himeji-city, Hyogo

ZIP/Postal Code

670-0981

Country

Japan

Facility Name

Novo Nordisk Investigational Site

City

Himeji-shi, Hyogo

ZIP/Postal Code

671-1227

Country

Japan

Facility Name

Novo Nordisk Investigational Site

City

Himeji-shi, Hyogo

ZIP/Postal Code

672-8043

Country

Japan

Facility Name

Novo Nordisk Investigational Site

City

Hirakata-Shi,Osaka

ZIP/Postal Code

573-1121

Country

Japan

Facility Name

Novo Nordisk Investigational Site

City

Hiroshima-shi, Hiroshima

ZIP/Postal Code

732-0066

Country

Japan

Facility Name

Novo Nordisk Investigational Site

City

Hiroshima-shi, Hiroshima

ZIP/Postal Code

732-0822

Country

Japan

Facility Name

Novo Nordisk Investigational Site

City

Hofu-shi, Yamaguchi

ZIP/Postal Code

747-0802

Country

Japan

Facility Name

Novo Nordisk Investigational Site

City

Ina-shi, Nagano

ZIP/Postal Code

396-8555

Country

Japan

Facility Name

Novo Nordisk Investigational Site

City

Kanagawa

ZIP/Postal Code

212-0016

Country

Japan

Facility Name

Novo Nordisk Investigational Site

City

Kawasaki-shi , Kanagawa

ZIP/Postal Code

214-0014

Country

Japan

Facility Name

Novo Nordisk Investigational Site

City

Kawasaki-shi, Kanagawa

ZIP/Postal Code

210-0852

Country

Japan

Facility Name

Novo Nordisk Investigational Site

City

Kawasaki-shi, Kanagawa

ZIP/Postal Code

213-8507

Country

Japan

Facility Name

Novo Nordisk Investigational Site

City

Kobe-shi, Hyogo

ZIP/Postal Code

650-0017

Country

Japan

Facility Name

Novo Nordisk Investigational Site

City

Kodaira-shi, Tokyo

ZIP/Postal Code

187-8551

Country

Japan

Facility Name

Novo Nordisk Investigational Site

City

Koriyama-shi, Fukushima

ZIP/Postal Code

963-8052

Country

Japan

Facility Name

Novo Nordisk Investigational Site

City

Kurashiki-shi, Okayama

ZIP/Postal Code

710-0813

Country

Japan

Facility Name

Novo Nordisk Investigational Site

City

Mitaka-shi,Tokyo

ZIP/Postal Code

181-0013

Country

Japan

Facility Name

Novo Nordisk Investigational Site

City

Nerima-ku, Tokyo

ZIP/Postal Code

179-0072

Country

Japan

Facility Name

Novo Nordisk Investigational Site

City

Niigata-shi, Niigata

ZIP/Postal Code

950-0983

Country

Japan

Facility Name

Novo Nordisk Investigational Site

City

Obu-shi, Aichi

ZIP/Postal Code

474-8511

Country

Japan

Facility Name

Novo Nordisk Investigational Site

City

Okayama-shi, Okayama

ZIP/Postal Code

703-8265

Country

Japan

Facility Name

Novo Nordisk Investigational Site

City

Shimotsuke-shi, Tochigi

Country

Japan

Facility Name

Novo Nordisk Investigational Site

City

Shinjuku-ku, Tokyo

ZIP/Postal Code

160-0017

Country

Japan

Facility Name

Novo Nordisk Investigational Site

City

Shinjuku-ku, Tokyo

ZIP/Postal Code

160-8582

Country

Japan

Facility Name

Novo Nordisk Investigational Site

City

Shizuoka-shi, Shizuoka

ZIP/Postal Code

424-8636

Country

Japan

Facility Name

Novo Nordisk Investigational Site

City

Takamatsu-shi, Kagawa

ZIP/Postal Code

760-8557

Country

Japan

Facility Name

Novo Nordisk Investigational Site

City

Takatsuki-Shi, Osaka

ZIP/Postal Code

569-1192

Country

Japan

Facility Name

Novo Nordisk Investigational Site

City

Tokorozawa-shi,Saitama

ZIP/Postal Code

359-1141

Country

Japan

Facility Name

Novo Nordisk Investigational Site

City

Tokushima-shi, Tokushima

ZIP/Postal Code

770-0852

Country

Japan

Facility Name

Novo Nordisk Investigational Site

City

Tokyo

ZIP/Postal Code

100-0005

Country

Japan

Facility Name

Novo Nordisk Investigational Site

City

Tokyo

ZIP/Postal Code

103-0028

Country

Japan

Facility Name

Novo Nordisk Investigational Site

City

Tokyo

ZIP/Postal Code

136-0075

Country

Japan

Facility Name

Novo Nordisk Investigational Site

City

Tokyo

ZIP/Postal Code

156-0041

Country

Japan

Facility Name

Novo Nordisk Investigational Site

City

Tokyo

ZIP/Postal Code

160-0023

Country

Japan

Facility Name

Novo Nordisk Investigational Site

City

Toride-shi, Ibaraki

ZIP/Postal Code

302-0004

Country

Japan

Facility Name

Novo Nordisk Investigational Site

City

Toyonaka-shi, Osaka

ZIP/Postal Code

560-0004

Country

Japan

Facility Name

Novo Nordisk Investigational Site

City

Wako-shi, Saitama

ZIP/Postal Code

351-0111

Country

Japan

Facility Name

Novo Nordisk Investigational Site

City

Yokohama-shi, Kanagawa

ZIP/Postal Code

223-0059

Country

Japan

Facility Name

Novo Nordisk Investigational Site

City

Busan

ZIP/Postal Code

49201

Country

Korea, Republic of

Facility Name

Novo Nordisk Investigational Site

City

Daejeon

ZIP/Postal Code

35015

Country

Korea, Republic of

Facility Name

Novo Nordisk Investigational Site

City

Gwangju

ZIP/Postal Code

61469

Country

Korea, Republic of

Facility Name

Novo Nordisk Investigational Site

City

Gyeonggi-do

ZIP/Postal Code

13620

Country

Korea, Republic of

Facility Name

Novo Nordisk Investigational Site

City

Incheon

ZIP/Postal Code

21565

Country

Korea, Republic of

Facility Name

Novo Nordisk Investigational Site

City

Incheon

ZIP/Postal Code

22332

Country

Korea, Republic of

Facility Name

Novo Nordisk Investigational Site

City

Seoul

ZIP/Postal Code

04763

Country

Korea, Republic of

Facility Name

Novo Nordisk Investigational Site

City

Seoul

ZIP/Postal Code

05030

Country

Korea, Republic of

Facility Name

Novo Nordisk Investigational Site

City

Seoul

ZIP/Postal Code

05505

Country

Korea, Republic of

Facility Name

Novo Nordisk Investigational Site

City

Seoul

ZIP/Postal Code

06351

Country

Korea, Republic of

Facility Name

Novo Nordisk Investigational Site

City

Seoul

ZIP/Postal Code

07804

Country

Korea, Republic of

Facility Name

Novo Nordisk Investigational Site

City

Breda

ZIP/Postal Code

4818 CK

Country

Netherlands

Facility Name

Novo Nordisk Investigational Site

City

Den Bosch

ZIP/Postal Code

5223 LA

Country

Netherlands

Facility Name

Novo Nordisk Investigational Site

City

Nijmegen

ZIP/Postal Code

6525 GA

Country

Netherlands

Facility Name

Novo Nordisk Investigational Site

City

Kraków

State/Province

Małopolskie

ZIP/Postal Code

30-721

Country

Poland

Facility Name

Novo Nordisk Investigational Site

City

Bydgoszcz

ZIP/Postal Code

85-163

Country

Poland

Facility Name

Novo Nordisk Investigational Site

City

Kielce

ZIP/Postal Code

25-411

Country

Poland

Facility Name

Novo Nordisk Investigational Site

City

Kraków

ZIP/Postal Code

30-688

Country

Poland

Facility Name

Novo Nordisk Investigational Site

City

Kraków

ZIP/Postal Code

31-505

Country

Poland

Facility Name

Novo Nordisk Investigational Site

City

Lublin

ZIP/Postal Code

20-818

Country

Poland

Facility Name

Novo Nordisk Investigational Site

City

Oswiecim

ZIP/Postal Code

32-600

Country

Poland

Facility Name

Novo Nordisk Investigational Site

City

Poznan

ZIP/Postal Code

61-853

Country

Poland

Facility Name

Novo Nordisk Investigational Site

City

Scinawa

ZIP/Postal Code

59-330

Country

Poland

Facility Name

Novo Nordisk Investigational Site

City

Sopot

ZIP/Postal Code

81-855

Country

Poland

Facility Name

Novo Nordisk Investigational Site

City

Warszawa

ZIP/Postal Code

01-684

Country

Poland

Facility Name

Novo Nordisk Investigational Site

City

Wroclaw

ZIP/Postal Code

53-659

Country

Poland

Facility Name

Novo Nordisk Investigational Site

City

Braga

ZIP/Postal Code

4710-243

Country

Portugal

Facility Name

Novo Nordisk Investigational Site

City

Coimbra

ZIP/Postal Code

3000-459

Country

Portugal

Facility Name

Novo Nordisk Investigational Site

City

Guimarães

ZIP/Postal Code

4835-044

Country

Portugal

Facility Name

Novo Nordisk Investigational Site

City

Lisboa

ZIP/Postal Code

1349-019

Country

Portugal

Facility Name

Novo Nordisk Investigational Site

City

Loures

ZIP/Postal Code

2674-514

Country

Portugal

Facility Name

Novo Nordisk Investigational Site

City

Matosinhos

ZIP/Postal Code

4464-513

Country

Portugal

Facility Name

Novo Nordisk Investigational Site

City

Porto

ZIP/Postal Code

4099-001

Country

Portugal

Facility Name

Novo Nordisk Investigational Site

City

Torres Vedras

ZIP/Postal Code

2560-280

Country

Portugal

Facility Name

Novo Nordisk Investigational Site

City

Targu Mures

State/Province

Mures

ZIP/Postal Code

540136

Country

Romania

Facility Name

Novo Nordisk Investigational Site

City

Timisoara

State/Province

Timis

ZIP/Postal Code

300766

Country

Romania

Facility Name

Novo Nordisk Investigational Site

City

Bucharest

ZIP/Postal Code

011025

Country

Romania

Facility Name

Novo Nordisk Investigational Site

City

Constanta

ZIP/Postal Code

900123

Country

Romania

Facility Name

Novo Nordisk Investigational Site

City

Constanta

ZIP/Postal Code

900591

Country

Romania

Facility Name

Novo Nordisk Investigational Site

City

Iasi

ZIP/Postal Code

700004

Country

Romania

Facility Name

Novo Nordisk Investigational Site

City

Sibiu

ZIP/Postal Code

550052

Country

Romania

Facility Name

Novo Nordisk Investigational Site

City

Timisoara

ZIP/Postal Code

300416

Country

Romania

Facility Name

Novo Nordisk Investigational Site

City

Ekaterinburg

ZIP/Postal Code

620030

Country

Russian Federation

Facility Name

Novo Nordisk Investigational Site

City

Ekaterinburg

ZIP/Postal Code

620075

Country

Russian Federation

Facility Name

Novo Nordisk Investigational Site

City

Moscow

ZIP/Postal Code

119021

Country

Russian Federation

Facility Name

Novo Nordisk Investigational Site

City

Moscow

ZIP/Postal Code

125373

Country

Russian Federation

Facility Name

Novo Nordisk Investigational Site

City

Moscow

ZIP/Postal Code

129226

Country

Russian Federation

Facility Name

Novo Nordisk Investigational Site

City

Omsk

ZIP/Postal Code

644043

Country

Russian Federation

Facility Name

Novo Nordisk Investigational Site

City

Rostov-on-Don

ZIP/Postal Code

344000

Country

Russian Federation

Facility Name

Novo Nordisk Investigational Site

City

Saint Petersburg

ZIP/Postal Code

190121

Country

Russian Federation

Facility Name

Novo Nordisk Investigational Site

City

Saint Petersburg

ZIP/Postal Code

191015

Country

Russian Federation

Facility Name

Novo Nordisk Investigational Site

City

Tomsk

ZIP/Postal Code

634009

Country

Russian Federation

Facility Name

Novo Nordisk Investigational Site

City

Ufa

ZIP/Postal Code

450054

Country

Russian Federation

Facility Name

Novo Nordisk Investigational Site

City

Belgrade

ZIP/Postal Code

11000

Country

Serbia

Facility Name

Novo Nordisk Investigational Site

City

Kovin

ZIP/Postal Code

26220

Country

Serbia

Facility Name

Novo Nordisk Investigational Site

City

Novi Sad

ZIP/Postal Code

21000

Country

Serbia

Facility Name

Novo Nordisk Investigational Site

City

Bratislava

ZIP/Postal Code

813 69

Country

Slovakia

Facility Name

Novo Nordisk Investigational Site

City

Kosice

ZIP/Postal Code

041 66

Country

Slovakia

Facility Name

Novo Nordisk Investigational Site

City

Krompachy

ZIP/Postal Code

053 42

Country

Slovakia

Facility Name

Novo Nordisk Investigational Site

City

Vranov nad Toplou

ZIP/Postal Code

093 01

Country

Slovakia

Facility Name

Novo Nordisk Investigational Site

City

Ljubljana

ZIP/Postal Code

SI-1000

Country

Slovenia

Facility Name

Novo Nordisk Investigational Site

City

Maribor

ZIP/Postal Code

SI-2000

Country

Slovenia

Facility Name

Novo Nordisk Investigational Site

City

Nova Gorica

ZIP/Postal Code

SI-5000

Country

Slovenia

Facility Name

Novo Nordisk Investigational Site

City

George

State/Province

Eastern Cape

ZIP/Postal Code

6529

Country

South Africa

Facility Name

Novo Nordisk Investigational Site

City

Bloemfontein

State/Province

Free State

ZIP/Postal Code

9301

Country

South Africa

Facility Name

Novo Nordisk Investigational Site

City

Johannesburg

State/Province

Gauteng

ZIP/Postal Code

2196

Country

South Africa

Facility Name

Novo Nordisk Investigational Site

City

Pretoria

State/Province

Gauteng

ZIP/Postal Code

0042

Country

South Africa

Facility Name

Novo Nordisk Investigational Site

City

Cape Town

State/Province

Western Cape

ZIP/Postal Code

7405

Country

South Africa

Facility Name

Novo Nordisk Investigational Site

City

Cape Town

State/Province

Western Cape

ZIP/Postal Code

7550

Country

South Africa

Facility Name

Novo Nordisk Investigational Site

City

Cape Town

State/Province

Western Cape

ZIP/Postal Code

7560

Country

South Africa

Facility Name

Novo Nordisk Investigational Site

City

Barcelona

ZIP/Postal Code

08025

Country

Spain

Facility Name

Novo Nordisk Investigational Site

City

Barcelona

ZIP/Postal Code

08028

Country

Spain

Facility Name

Novo Nordisk Investigational Site

City

Madrid

ZIP/Postal Code

28034

Country

Spain

Facility Name

Novo Nordisk Investigational Site

City

Madrid

ZIP/Postal Code

28041

Country

Spain

Facility Name

Novo Nordisk Investigational Site

City

Pozuelo de Alarcon

ZIP/Postal Code

28223

Country

Spain

Facility Name

Novo Nordisk Investigational Site

City

Sant Cugat del Vallès

ZIP/Postal Code

08195

Country

Spain

Facility Name

Novo Nordisk Investigational Site

City

Santander

ZIP/Postal Code

39008

Country

Spain

Facility Name

Novo Nordisk Investigational Site

City

Valencia

ZIP/Postal Code

46017

Country

Spain

Facility Name

Novo Nordisk Investigational Site

City

Malmö

ZIP/Postal Code

205 02

Country

Sweden

Facility Name

Novo Nordisk Investigational Site

City

Stockholm

ZIP/Postal Code

141 86

Country

Sweden

Facility Name

Novo Nordisk Investigational Site

City

Umeå

ZIP/Postal Code

901 85

Country

Sweden

Facility Name

Novo Nordisk Investigational Site

City

Biel-Bienne

ZIP/Postal Code

2501

Country

Switzerland

Facility Name

Novo Nordisk Investigational Site

City

Genève

ZIP/Postal Code

1205

Country

Switzerland

Facility Name

Novo Nordisk Investigational Site

City

Lausanne

ZIP/Postal Code

1011

Country

Switzerland

Facility Name

Novo Nordisk Investigational Site

City

St. Gallen

ZIP/Postal Code

9007

Country

Switzerland

Facility Name

Novo Nordisk Investigational Site

City

Kaohsiung City

ZIP/Postal Code

833

Country

Taiwan

Facility Name

Novo Nordisk Investigational Site

City

Kaohsiung

ZIP/Postal Code

807

Country

Taiwan

Facility Name

Novo Nordisk Investigational Site

City

Taichung

ZIP/Postal Code

404

Country

Taiwan

Facility Name

Novo Nordisk Investigational Site

City

Tainan City

ZIP/Postal Code

704302

Country

Taiwan

Facility Name

Novo Nordisk Investigational Site

City

Taipei

ZIP/Postal Code

100

Country

Taiwan

Facility Name

Novo Nordisk Investigational Site

City

Taipei

ZIP/Postal Code

112

Country

Taiwan

Facility Name

Novo Nordisk Investigational Site

City

Taoyuan City

ZIP/Postal Code

333

Country

Taiwan

Facility Name

Novo Nordisk Investigational Site

City

Altindag/Ankara

ZIP/Postal Code

06230

Country

Turkey

Facility Name

Novo Nordisk Investigational Site

City

Balcova / Izmir

ZIP/Postal Code

35330

Country

Turkey

Facility Name

Novo Nordisk Investigational Site

City

Eskisehir

ZIP/Postal Code

26040

Country

Turkey

Facility Name

Novo Nordisk Investigational Site

City

Istanbul

ZIP/Postal Code

34093

Country

Turkey

Facility Name

Novo Nordisk Investigational Site

City

Izmir

ZIP/Postal Code

35575

Country

Turkey

Facility Name

Novo Nordisk Investigational Site

City

Samsun

ZIP/Postal Code

55200

Country

Turkey

Facility Name

Novo Nordisk Investigational Site

City

Kharkiv

ZIP/Postal Code

61091

Country

Ukraine

Facility Name

Novo Nordisk Investigational Site

City

Odesa

ZIP/Postal Code

65031

Country

Ukraine

Facility Name

Novo Nordisk Investigational Site

City

Aberdeen

ZIP/Postal Code

AB25 2ZH

Country

United Kingdom

Facility Name

Novo Nordisk Investigational Site

City

Bath

ZIP/Postal Code

BA1 3NG

Country

United Kingdom

Facility Name

Novo Nordisk Investigational Site

City

Crowborough

ZIP/Postal Code

TN6 1NY

Country

United Kingdom

Facility Name

Novo Nordisk Investigational Site

City

Dundee

ZIP/Postal Code

DD1 9SY

Country

United Kingdom

Facility Name

Novo Nordisk Investigational Site

City

Edinburgh

ZIP/Postal Code

EH4 2XU

Country

United Kingdom

Facility Name

Novo Nordisk Investigational Site

City

Gloucestershire

ZIP/Postal Code

GL53 9DZ

Country

United Kingdom

Facility Name

Novo Nordisk Investigational Site

City

London

ZIP/Postal Code

EC2Y 8EA

Country

United Kingdom

Facility Name

Novo Nordisk Investigational Site

City

London

ZIP/Postal Code

SW17 0RE

Country

United Kingdom

Facility Name

Novo Nordisk Investigational Site

City

London

ZIP/Postal Code

W12 0NN

Country

United Kingdom

Facility Name

Novo Nordisk Investigational Site

City

Manchester

ZIP/Postal Code

M13 9WL

Country

United Kingdom

Facility Name

Novo Nordisk Investigational Site

City

Motherwell

ZIP/Postal Code

ML1 4UF

Country

United Kingdom

Facility Name

Novo Nordisk Investigational Site

City

Newcastle Upon Tyne

ZIP/Postal Code

NE4 5PL

Country

United Kingdom

Facility Name

Novo Nordisk Investigational Site

City

Oxford

ZIP/Postal Code

OX3 7JX

Country

United Kingdom

Facility Name

Novo Nordisk Investigational Site

City

Southampton

ZIP/Postal Code

SO30 3JB

Country

United Kingdom

Facility Name

Novo Nordisk Investigational Site

City

Swindon

ZIP/Postal Code

SN3 6BW

Country

United Kingdom

12. IPD Sharing Statement

Plan to Share IPD

Yes

IPD Sharing Plan Description

According to the Novo Nordisk disclosure commitment on novonordisk-trials.com

IPD Sharing URL

http://novonordisk-trials.com

Learn more about this trial

A Research Study Investigating Semaglutide in People With Early Alzheimer's Disease (EVOKE Plus)

We'll reach out to this number within 24 hrs

A Research Study Investigating Semaglutide in People With Early Alzheimer's Disease (EVOKE Plus)

Early Alzheimer´s Disease

About this trial

Eligibility Criteria

Sites / Locations

Arms of the Study

Arm 1

Arm 2

Outcomes

Primary Outcome Measures

Secondary Outcome Measures

Full Information

1. Study Identification

2. Study Status

3. Sponsor/Collaborators

4. Oversight

5. Study Description

6. Conditions and Keywords

7. Study Design

8. Arms, Groups, and Interventions

10. Eligibility

12. IPD Sharing Statement

Learn more about this trial