Effect of Inspiratory Muscle Training on Physiological Function and Clinical Outcomes After Lung Transplant
Post-Lung Transplantation Bronchiectasis
About this trial
This is an interventional supportive care trial for Post-Lung Transplantation Bronchiectasis focused on measuring Inspiratory muscle training, post lung transplant, exercise capacity, breathing
Eligibility Criteria
Inclusion Criteria:
- All patients who undergo single- or double-lung transplant at Mayo Clinic Florida.
Exclusion Criteria:
- Patients who do not survive the intra-operative period during the transplant surgery.
- Patients undergoing retransplantation.
- Patients undergoing multiorgan transplantation.
- Patients who are not willing to or who are unable to give written informed consent.
Sites / Locations
- Mayo Clinic in FloridaRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
Placebo Comparator
12-weeks pulmonary rehabilitation training plus inspiratory muscle training
12-weeks pulmonary rehabilitation plus placebo (inactive) inspiratory muscle
To assess maximum inspiratory pressure, you will be asked to breathe through a device called POWERBreathe Plus®. This device is commercially available and will be provided to you by the study. You will be asked to use this device twice per day, 5 days per week, for 12 weeks. Each session will require you to breathe into the device 30 times. You can use the device at home.
To assess maximum inspiratory pressure with placebo, you will be asked to breathe through a device called POWERBreathe Plus®. This device is commercially available and will be provided to you by the study. You will be asked to use this device twice per day, 5 days per week, for 12 weeks. Each session will require you to breathe into the device 30 times. You can use the device at home. The resistance will be set to about 5% throughout the study.