Biomaterial Clinical Performance in a Socket Preservation Model
Bone Loss, Alveolar Bone Resorption
About this trial
This is an interventional treatment trial for Bone Loss
Eligibility Criteria
Inclusion Criteria:
- Aged 18 or over
- requiring extraction of teeth in the premolar region and anterior maxilla (15-25), presence of intact 2/3 or less, buccal bone plate
- ASA (Physical Status Classification System, American Society of Anesthesiologist) I or II.
Exclusion Criteria:
- patients with uncompensated systemic diseases, metabolic and healing disorders, i.e. diabetes mellitus, hyperparathyroidism, cancer, HIV,
- heavy smokers (>5 cigarettes/ day),
- bone metabolic diseases,
- severe renal dysfunction or liver disease,
- had received systemic corticosteroids or other immunosuppressive agents, radiation therapy and/or chemotherapy for the past 2 months,
- active infections in the surgical site
- patients with periodontal or/and endodontic disease
Sites / Locations
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
Socket Preservation Alloplastic Material
Extraction Socket Spontaneous Healing
10 Consecutive Patients with hopeless teeth and 1/3 or more buccal bone resorption will be placed in a therapy go bone regeneration called socket preservation technique. The surgery will include placement of 2/3 biphasic calcium sulfate cement matrix's with hydroxyapatite (HA granules) to fill the alveolar defects, and place a resorbable membrane sutured to adjacent tissue, to avoid material leakage. No flap retraction. 3 Month later an implant will be placed, and a bone biopsy of the healed socket harvested. 2 Month later a final Zirconia ceramic crown screw retained to the osseointegrated implant. Primary (T0) and Secondary (T1) stability measured with ISQ values. Intraoral Scanner and an STL File will be taken at T0 , T1 and T2 for volumetric alteration evaluation.
10 Consecutive patients with a tooth extraction without the aim of placing a future implant and without Biomaterial filler placed in the socket. Spontaneous healing