Early Intervention for Youth at High Risk for Bipolar Disorder (KEY)
Bipolar Disorder
About this trial
This is an interventional prevention trial for Bipolar Disorder focused on measuring psychosocial treatment, early intervention, prevention, adolescent
Eligibility Criteria
Inclusion Criteria:
- Age 12-18 years
- A parent with a diagnosis of BP I or II
- Baseline Risk Calculator score>0.05;
- Able/willing to give informed consent/assent
Exclusion Criteria:
- A lifetime BP spectrum disorder
- Current unstabilized psychiatric symptoms
- Evidence of developmental disorder or central nervous system disorder
Sites / Locations
- Nicole ArnoldRecruiting
Arms of the Study
Arm 1
Arm 2
Active Comparator
Active Comparator
Interpersonal and Social Rhythm Therapy (IPSRT)
Healthy Lifestyle Intervention (HL)
Interpersonal and Social Rhythm Therapy (IPSRT) for at-risk offspring includes 8 sessions over 6 months delivered via secure telemedicine platform. The basis of the intervention is the treatment manual iteratively developed and tested in close consultation with content experts during our open pilot study and R34.The intervention focuses on education about BP risk, stabilizing sleep and daily routines and interpersonal relationships.
HL is based on the treatment manual developed in a prior trial for adults and adolescents with BP. HL includes psychoeducational modules that aim to teach patients about health risks and help them achieve a balanced lifestyle to optimize physical and mental health. In HL, patients are taught to develop and maintain an individualized lifestyle plan and provided support and encouragement for making progress toward their goals. HL clinicians will deliver 8 sessions over 6 months via secure telehealth platform.