Vitamin D, Omega-3, and Combination Vitamins B, C and Zinc Supplementation for the Treatment and Prevention of COVID-19 (NUTROVID)
Covid19
About this trial
This is an interventional other trial for Covid19 focused on measuring Covid19, Nutritional supplements, Vitamin B, Vitamin C, Elemental Zinc, Cytokine storm, Vitamin D, Vitamin B Complex, Omega 3
Eligibility Criteria
Positive SARS-CoV-2 Test group (Target enrollment: N=1,800) NUTROVID Treat Trial: Adult men/women recently diagnosed with COVID-19 (positive PCR test for SARS-CoV-2 coronavirus) within <=5 days of symptom onset; and satisfying one of these risk factors: >=50 years old; or Diabetic & >=40 years old; or Obese & >=40 years old.
Negative SARS-CoV-2 Test group (Target enrollment: N=1,800) NUTROVID Prevent Trial: Adult men/women recently tested negative for COVID-19 (negative PCR test for SARS-CoV-2 coronavirus); and satisfying one of these risk factors: >=50 years old; or Diabetic & >=40 years old; or Obese & >=40 years old.
Signed Informed Consent Form
Exclusion Criteria:
- Patients requiring immediate intubation or deemed likely to die within 48 hours.
- Patients deemed likely for transfer to an ICU within 48 hours.
- Patients currently taking oral corticosteroids for any reason at the time of presentation for care.
- Patients included in any other interventional trial.
- Uncontrolled bacterial superinfection.
- Severe chronic kidney disease (stage 4) or requiring dialysis (i.e. eGFR < 30).
- Pregnant women or women who are breastfeeding.
- Immunocompromised patients.
- Any patient with recent treatment (past 30 days) of immunosuppressive agents including (but not restricted to) DMARDs, corticosteroids, antibody therapy, intravenous immunoglobulins etc.
- Patients with acute myocardial infarction.
Sites / Locations
- Hospital de Soledad
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Arm 5
Arm 6
Arm 7
Arm 8
Active Comparator
Active Comparator
Active Comparator
Active Comparator
Active Comparator
Active Comparator
Active Comparator
Placebo Comparator
1 - Vitamin D, Omega 3, Vitamins B, C, Zinc
2 - Vitamin D, Omega 3
3 - Vitamin D, Vitamins B, C, Zinc
4 - Vitamin D
5 - Omega 3, Vitamins B, C, Zinc,
6 - Omega 3
7 - Vitamins B, C, Zinc
8 - No Interventions
Vitamin D of F1 Omega 3 of F2 Vitamins B, C, Zinc of F3 [60 days]
Vitamin D of F1 Omega 3 of F2 Placebo of F3 [60 days]
Vitamin D of F1 Placebo of F2 Vitamins B, C, Zinc of F3 [60 days]
Vitamin D of F1 Placebo of F2 Placebo of F3 [60 days]
Placebo of F1 Omega 3 of F2 Vitamins B, C, Zinc of F3 [60 days]
Placebo of F1 Omega 3 of F2 Placebo of F3 [60 days]
Placebo of F1 Placebo of F2 Vitamins B, C, Zinc of F3 [60 days]
Placebo of F1 Placebo of F2 Placebo of F3 [60 days]