Optimizing Physical Function Before Cancer Surgery in Older People at Risk (CanOptiPhys)
Colorectal Cancer, Postoperative Complications
About this trial
This is an interventional treatment trial for Colorectal Cancer focused on measuring Preoperative Exercise
Eligibility Criteria
Inclusion Criteria:
- Scheduled surgery due to colorectal cancer or liver metastases from colorectal cancer
- Age ≥65
- A maximal walking speed below 2 meters per second
- Understands and speaks the Swedish language
Exclusion Criteria:
- Planned hyperthermic intraperitoneal chemotherapy (HIPEC) procedure or flap surgery
- Health conditions that prevent participation in assessment or exercise. Such conditions include, but are not limited to, unstable heart disease, severe systematic illness or orthopaedic conditions that may prohibit exercise.
- The need for surgery within 2 weeks
- Permanent wheelchair user
- Residence outside of Stockholm County
Sites / Locations
- Karolinska University Hospital Huddinge
- Karolinska University Hospital Solna
- Ersta hospital
- Stockholm South General Hospital
Arms of the Study
Arm 1
Arm 2
Experimental
No Intervention
Exercise
Control group
A high-intensity, home-based, exercise program consisting of inspiratory muscle training (IMT), endurance- and functional strength exercise. The sessions will supervised by a physiotherapist during six occasions and start 2-3 weeks before surgery. IMT will be conducted with an intensity starting from 50 % of maximal capacity, with a self-reported effort of 5-7 on the Borgs CR-10 scale. Endurance and functional strength exercises will be performed at a self-reported effort of 7-8. Interval training, chair stand- and step-up exercises will be key components of the exercise program. Furthermore, the program will include task-specific exercises based on the participants self-expressed needs. On non-supervised days, participants will perform IMT twice a day as well as endurance and strength training, 2-3 days per week with 1-2 days per week of active recovery in the form of moderate intensity walks. This will be monitored with an activity journal and an accelerometer.
Participants in the control group receive pre- and postoperative care as usual. In addition, they will be encouraged to follow the WHO guidelines of moderate intensity aerobic physical activity for at least 150 min per week. Their activity level will be monitored with an accelerometer.