Weathering the Storm: Lung, Heart, and Brain Vascular Rehabilitation for COVID-19
Covid19
About this trial
This is an interventional basic science trial for Covid19 focused on measuring Cerebral Blood Flow, Exercise
Eligibility Criteria
Inclusion Criteria:
- BMI<40,
- 1-4 weeks post active COVID19 infection
- physician approval for undertaking exercise testing and training.
- Adequate intracranial ultrasound windows
Exclusion Criteria:
- Lingering COVID19 symptomology
- cardiovascular disease
- pulmonary disease
- cerebrovascular disease
- taking medication that influences heart rate, blood pressure, or cerebrovascular function,
- severe obesity (BMI >40)
- metabolic comorbidities (diabetes, metabolic syndrome),
- recently been diagnosed with a mild traumatic brain injury (within past 6 months).
Sites / Locations
- University of Illinois at Chicago
Arms of the Study
Arm 1
Arm 2
Active Comparator
Experimental
Exercise Training (EXT)
Inspiratory Muscle and Exercise Training (IMET)
Research participants will complete six weeks of supervised progressive aerobic and resistance exercise training (EXT). Cardiopulmonary, cerebral and peripheral vascular function will be measured pre and post EXT.
Research participants will complete six weeks of supervised aerobic and resistance exercise training in addition to supervised respiratory muscle training (IMET). IMET sessions will be performed similar to EXT, with the exception of having sessions of at-home IMT training. On these days, all training will be spread out over a 2-hour session with periods of IMT training occurring at the beginning, middle, and end of the session. Cardiopulmonary, cerebral and peripheral vascular function will be measured pre and post IMET.