The Effect of Electroacupuncture on Nerve Pain Caused by Chemotherapy (Chemotherapy-Induced Peripheral Neuropathy)
Chemotherapy-induced Peripheral Neuropathy, Nerve Pain
About this trial
This is an interventional treatment trial for Chemotherapy-induced Peripheral Neuropathy focused on measuring Chemotherapy-induced Peripheral Neuropathy, CIPN, Electroacupuncture, Nerve pain, Cancer survivor, 20-246, Memorial Sloan Kettering Cancer Center
Eligibility Criteria
Inclusion Criteria:
- English-proficient men and women aged ≥18 years
- Free of oncologic disease by clinical examination and history
- Completed neurotoxic chemotherapy such as platinum agents, taxanes, vinca alkaloids, and bortezomib at least three months prior to enrollment
- Diagnosis of CIPN based on symptom history, loss of deep tendon reflexes, or the presence of symmetrical stocking-glove pain, numbness, or paresthesia73
- Grade ≥1 sensory pain based on the NCI Common Terminology Criteria for Adverse Events (CTCAE) version 5.0
- Self-reported moderate to severe CIPN pain, as defined by a score of 4 or greater on the BPI-SF average pain item over the past week
- On a stable regimen (no change in the past three months) if taking anti-neuropathy or other pain medications
- Willing to adhere to requirement that no new pain medication be taken throughout the first 12 weeks of the study period
- Willing to adhere to all study-related procedures, including randomization to one of the two possible acupuncture treatments
Exclusion Criteria:
- Patients with a pacemaker or other electronically charged medical device
- Use of acupuncture for symptom management within the past 12 months
Sites / Locations
- Memorial Sloan Kettering Basking Ridge (Limited protocol activities)Recruiting
- Memorial Sloan Kettering Monmouth (Limited protocol activities)Recruiting
- Memorial Sloan Kettering Bergen (Limited Protocol Activities)Recruiting
- Memorial Sloan - Kettering Cancer CenterRecruiting
- Memorial Sloan Kettering Nassau (Limited protocol activities)Recruiting
Arms of the Study
Arm 1
Arm 2
Experimental
Placebo Comparator
Electroacupuncture Arm
Sham Acupuncture Arm
The study participants will include 250 cancer survivors who have completed neurotoxic agent containing chemotherapy at least three months prior and have persistent moderate to severe Chemotherapy-Induced Peripheral Neuropathy/CIPN pain randomized to one of two study arms.
The study participants will include 250 cancer survivors who have completed neurotoxic agent containing chemotherapy at least three months prior and have persistent moderate to severe Chemotherapy-Induced Peripheral Neuropathy/CIPN pain randomized to one of two study arms.