Back to resultsA Study Evaluating the Efficacy and Safety of Adjuvant Giredestrant Compared With Physician's Choice of Adjuvant Endocrine Monotherapy in Participants With Estrogen Receptor-Positive, HER2-Negative Early Breast Cancer (lidERA Breast Cancer)
Primary Purpose
Early Breast Cancer
Status
Active
Phase
Phase 3
Locations
International
Study Type
Interventional
Intervention
Giredestrant
Endocrine Therapy of Physician's Choice
LHRH Agonist
Sponsored by
About this trial
This is an interventional treatment trial for Early Breast Cancer
Eligibility Criteria
Inclusion Criteria:
- Documented estrogen receptor (ER)-positive and HER2-negative breast tumor, as assessed locally on a primary disease specimen
- Participants who have multicentric (the presence of two of more tumor foci within different quadrants of the same breast) and/or multifocal (the presence of two or more tumor foci within a single quadrant of the breast) breast cancer are also eligible if all examined tumors meet pathologic criteria for ER positivity and HER2 negativity
- Participants must have undergone definitive surgery of their primary breast tumor(s) and axillary lymph nodes (axillary lymph node dissection [ALND] and/or sentinel lymph node biopsy [SLNB])
- Participants who received or will be receiving adjuvant chemotherapy must have completed adjuvant chemotherapy prior to randomization. Participants may also have received neoadjuvant chemotherapy. A washout period of at least 21 days is required between last adjuvant chemotherapy dose and randomization.
- Resolution of all acute toxic effects of prior anti-cancer therapy or surgical procedures to NCI CTCAE v5.0 Grade 1 or better (except alopecia, Grade ≤2 peripheral neuropathy, arthralgia or other toxicities not considered a safety risk for the participant per the investigator's judgment)
- Participants have received (neo)adjuvant chemotherapy and/or had surgery and had no prior endocrine therapy are eligible, provided that they are enrolled within 12 months following definitive breast cancer surgery
- Participants who have confirmed availability of an untreated primary breast tumor tissue specimen suitable for biomarker testing (i.e., representative archived formalin-fixed, paraffin-embedded [FFPE] tissue block [preferred] or 15-20 slides containing unstained, freshly cut, serial sections), with associated de-identified pathology report is required. Although 15-20 slides are preferred, if only 10-14 slides are available, the individual may still be eligible for the study.
- Participants with node-positive and node-negative disease are eligible provided they meet additional risk criteria as defined in the protocol
- Eastern Cooperative Oncology Group (ECOG) Performance Status 0, 1, or 2
- Able and willing to swallow, retain, and absorb oral medication
- Adequate organ function
Exclusion Criteria:
- Pregnant or breastfeeding, or intending to become pregnant during the study or within 10 days after the final dose of giredestrant, or within the time period specified per local prescribing guidelines after the final dose of the endocrine therapy of physician's choice
- Received treatment with investigational therapy within 28 days prior to initiation of study treatment or is currently enrolled in any other type of medical research judged by the sponsor not to be scientifically or medically compatible with this study
- Receiving or planning to receive a CDK4/6 inhibitor as (neo)adjuvant therapy. A short course of up to 12 weeks of neoadjuvant or adjuvant treatment with CDK4/6 inhibitor therapy prior to randomization is allowed.
- Active cardiac disease or history of cardiac dysfunction
- Diagnosed with Stage IV breast cancer
- A history of any prior (ipsilateral and/or contralateral) invasive breast cancer or ductal carcinoma in situ (DCIS). Participants with a history of contralateral DCIS treated by only local regional therapy at any time may be eligible.
- A history of any other malignancy within 3 years prior to screening, except for appropriately treated carcinoma in situ of the cervix, nonmelanoma skin carcinoma, or Stage I uterine cancer
- Any prior endocrine treatment with selective ER modulators (e.g., tamoxifen), degraders, or aromatase inhibitors. A short course of neoadjuvant or adjuvant endocrine therapy (up to 12 weeks) is allowed.
- Clinically significant liver disease consistent with Child-Pugh Class B or C, including active hepatitis (e.g., hepatitis B virus [HBV] or hepatitis C virus [HCV]), current alcohol abuse, cirrhosis, or positive test for viral hepatitis
- Known allergy or hypersensitivity to any of the study drugs or any of their excipients
- Pre- and perimenopausal participants or male participants who have a known hypersensitivity to LHRH agonists
- A documented history of hemorrhagic diathesis, coagulopathy, or thromboembolism
- Renal dysfunction that requires dialysis
- A major surgical procedure unrelated to breast cancer within 28 days prior to randomization
- A serious infection requiring oral or IV antibiotics within 14 days prior to screening or other clinically significant infection (e.g., COVID-19) within 14 days prior to screening
- Any serious medical condition or abnormality in clinical laboratory tests that, in the investigator's judgment, precludes an individual's safe participation in and completion of the study
- Unable or unwilling to comply with the requirements of the protocol in the opinion of the investigator
Sites / Locations
- Southern Cancer Center
- CBCC Global Research Inc., at Comprehensive Blood and Cancer Center
- Arrowhead Regional Medical Center
- Cancer and Blood Specialty Clinic
- Long Beach Memorial Medical Center
- Keck Medicine of USC ? Newport Beach
- The Center for Cancer Prevention and Treatment at St.Joseph Hospital of Orange
- Stanford University Medical Center
- Kaiser Permanente - Roseville
- Kaiser Permanente - San Diego
- Kaiser Permanente - San Francisco (2238 Geary)
- Stanford Cancer Center South Bay
- Sansum Clinic
- Kaiser Permanente - Santa Clara
- UCLA Hematology/Oncology
- St Joseph Heritage Healthcare
- Torrance Memorial Physician Network/Cancer Care
- Kaiser Permanente - Vallejo
- Valley Breast Care and Women's Health Center
- Rocky Mountain Cancer Centers (Longmont) - USOR
- Stamford Hospital; Clincal Trials Office - 1st Fl - Bennett Cancer Cente
- University of Florida; UF Health Shands Cancer Hospital
- Memorial Healthcare System - Memorial Regional Hospital
- Baptist - MD Anderson Cancer Center
- Mount Sinai Comprehensive Cancer Center
- Miami Cancer Institute of Baptist Health, Inc.
- Orlando Health Cancer Institute
- Miami Cancer Institute-Plantation
- Memorial Health University Cancer Center
- University of Illinois at Chicago
- University of Chicago Hospital
- Elmhurst Cancer Center
- Joliet Oncology Hematology Associates, Ltd.
- Edward Cancer Center Naperville
- Edward Cancer Center Plainfield
- Oncology Associates at Mercy Medical Center
- University of Iowa
- Cancer Center of Kansas - Kingman
- Lahey Clinic Med Ctr
- University of Kentucky; Markey Cancer Center
- Norton Cancer Institute - MDC
- Hematology/Oncology Clinic, LLP
- University Medical Center New Orleans
- UPMC Western Maryland - Schwab Family Cancer Center
- University of Maryland; St. Joseph Medical Center
- Massachusetts General Hospital; Lurie Center for Autism
- University Of Michigan
- Barbara Ann Karmanos Cancer Institute
- Metro-Minnesota Community Oncology Research Consortium
- University of Missouri-Columbia; Ellis Fischel Cancer Center
- St. Vincent Frontier Cancer Center
- Nebraska Cancer Specialists
- University of Nebraska Medical Center
- Comprehensive Cancer Centers of Nevada
- MD Anderson Cancer Center at Cooper
- Hunterdon Hematology Oncology
- Rutgers Cancer Institute of New Jersey
- Roswell Park Cancer Institute
- Queens Hospital Cancer Center
- NYU Winthrop Hospital
- New York University Cancer Cen
- Stony Brook Univ Cancer Ctr
- Messino Cancer Centers
- Levine Cancer Institute
- First Health of the Carolinas
- Rex Cancer Center
- UNC Cancer Care at Nash
- Wake Forest Baptist Medical Center
- Aultman Hospital
- Oncology Hematology Care Inc
- University Hospitals Cleveland Medical Center
- Cleveland Clinic; Taussig Cancer Institute
- Columbus NCORP
- Stefanie Spielman Comprehensive Breast Center
- SCRI Mark H. Zangmeister Center
- Kaiser Permanente-Northwest Region
- Oncology Associates of Oregon, P.C.; Willamette Valley Cancer Institute
- Northwest Cancer Specialists, P.C.
- Pinnacle Health
- Penn State Univ. Milton S. Hershey Medical Center; Department of Investigational Drug Services
- Allegheny Cancer Center
- University of Pittsburgh Medical Center; Division of Hematology-Oncology
- Reading Hospital
- UPMC Williamsport, Divine Providence Campus
- Women & Infants Hospital
- Avera Cancer Institute
- West Cancer Center & Research Institute
- Tennessee Oncology NASH - SCRI - PPDS
- Texas Oncology, P.A. - El Paso; West
- Texas Oncology (Flower Mound) - USOR
- Texas Oncology-Fort Worth Cancer Center
- Baylor College of Medicine Medical Center
- Houston Methodist Cancer Center
- Joe Arrington Cancer Research & Treatment Center
- Texas Oncology (McAllen) - USOR
- Texas Oncology McKinney
- USOR - Texas Oncology - San Antonio Northeast
- US Oncology Research, Inc.
- Texas Oncology (Tyler) - USOR
- Texas Oncology (Waco) - USOR
- Lynchburg Hem Onc Clinic Inc
- Bon Secours Mercy Health
- Virginia Oncology Associates
- Virginia Commonwealth University - Massey Cancer Center
- Oncology and Hematology Associates of Southwest Virginia, Inc.,-Blacksburg
- Swedish Cancer Institute; IDS Pharmacy
- West Virginia University Hospitals Inc
- University of Wisconsin
- Froedtert and The Medical College of Wisconsin
- Hospital Italiano Regional del Sur
- Fundacion Intectus
- Instituto de Investigaciones Clinicas-Mar del Plata
- Instituto de Investigaciones Metabólicas (IDIM); Diabetes
- Fundación CENIT para la Investigación en Neurociencias
- Centro Oncologico Korben
- Fundacion Medica de Rio Negro Y Nuequen
- Consultorios Médicos Dr. Doreski
- Centro Médico Privado CEMAIC
- Sanatorio Allende Servicio Nefrología
- Fundación Ars Medica
- Centro Oncologico Riojano Integral (CORI)
- Centro de Investigaciones Medicas Mar Del Plata
- Hospital Privado de La Comunidad
- Centro de Investigacion Pergamino SA
- Hospital Alemán
- Instituto de Especialidades de la Salud Rosario - Clínica del Tórax
- Instituto Medico de la Fundacion Estudios Clinicos
- Sanatorio Parque de Rosario
- Instituto de Oncologia de Rosario
- Centro de Investigacion en Oncologie - IMAC
- Centro Polivalente de Asistencia e Investigacion Clinica - CER San Juan
- Centro Médico Privado de Reumatología
- Centro Medico San Roque
- Organizacion Medica de Investigacion
- Centro de Investigación Clínica ? Clínica Viedma
- Border Medical Oncology Research Unit
- Bankstown-Lidcombe Hospital
- Campbelltown Hospital
- Kinghorn Cancer Centre; Pharmacy Department
- Liverpool Hospital; Cancer Therapy Centre
- Mater Hospital; Patricia Ritchie Centre for Cancer Care and Research
- Westmead Hospital; Pharmacy Distribution Centre
- North Coast Cancer Institute - Port Macquarie
- Nepean Cancer Care Centre
- Wesley Medical Centre; Clinic For Haematology and Oncology
- Mater Cancer Care Centre
- Cairns Hospital; Renal Services
- Townsville Hospital
- Princess Alexandra Hospital
- Royal Adelaide Hospital
- St Andrews Medical Centre
- Flinders Medical Centre
- Adelaide Cancer Centre
- ICON Cancer Care Hobart
- Bendigo Hospital
- Box Hill Hospital
- Victorian Breast and Oncology Care
- Northern Hospital
- Frankston Hospital; Oncology/Haematology
- Maroondah Hospital; Breast Clinic
- Goulburn Valley Health
- Sunshine Hospital
- South West Oncology
- Ballarat Oncology & Haematology
- Sir Charles Gairdner Hospital
- LKH-Universitätsklinikum Klinikum Graz
- Medizinische Universitat Innsbruck; Department of Internal Medicine, Pneumology Centre
- Ordensklinikum Linz GmbH
- LKH Rankweil, Interne E
- Universitätsklinikum Salzburg
- Universitätsklinikum St. Pölten; Klinische Abteilung für Innere Medizin 1
- A.ö. Krankenhaus der Barmherzigen Brüder
- Oö. Gesundheits- und Spitals-AG/LKH Steyr
- Klinikum Wels-Grieskirchen GmbH
- Medizinische Universitat Wien Medical University of Vienna
- Institute Jules Bordet; Med Onc & Translational Rsch
- Cliniques Universitaires Saint-Luc
- Grand Hopital de Charleroi asbl
- UZ Antwerpen
- UZ Gent
- UZ Leuven
- CH de l'Ardenne (Libramont)
- Chu Sart Tilman; Medical Oncology
- Centre Hospitalier Chrétien MontLégia
- CHR de la Citadelle, Pharmacie
- Clinique Sainte-Elisabeth; Oncologie
- Cliniques Universitaires UCL de Mont-Godinne
- GZA Ziekenhuizen Antwerpen campus Sint-Augustinus
- Clinical Center Banja Luka
- Clinical Hospital Mostar
- Clinical Center University of Sarajevo; Oncology Institute
- University Clinical Center Tuzla
- Nucleo de Oncologia da Bahia - NOB
- Centro de Oncologia da Bahia; Centro Médico Iguatemi
- Centro Odonito Medico Linus Pauling - Clinica de O
- Terapia de Inovação Clínica Assistência Multidiciplinar Em Oncologia Ética
- Centro de Pesquisas Clinicas em Oncologia - CPCO
- Hospital Araujo Jorge
- Cenantron - Centro Avancado de Tratamento Oncologico
- Oncocentro Belo Horizonte
- Hospital de Clinicas de Porto Alegre HCPA PPDS
- Hospital do Cancer de Pernambuco - HCP
- Instituto Nacional de Cancer - INCa; Oncologia
- Universidade de Caxias do Sul - Rio Grande do Sul
- Hospital de Caridade de Ijui; Oncologia
- Hospital Bruno Born; Oncologia
- Hospital São Vicente de Paulo X
- Hospital Moinhos de Vento
- Irmandade Da Santa Casa de Misericordia de Porto Alegre; Hospital Dom Vicente Scherer
- Hospital Mae de Deus
- Hospital Sao Lucas - PUCRS
- Hospital Nossa Senhora da Conceição; Ambulatório de Pneumologia
- Clinica de Neoplasias Litoral
- *X*Fundação Pio XII Hospital de Câncer de Barretos
- Hospital Amaral Carvalho
- Instituto de Oncologia Clínica de Piracicaba
- Faculdade de Medicina do ABC - FMABC
- Fundação Faculdade Regional de Medicina de São José do Rio Preto
- Instituto do Cancer do Estado de Sao Paulo - ICESP
- Onco Star Sp Oncologia Ltda
- Instituto de Oncologia de Sorocaba - CEPOS
- Instituto Brasileiro De Controle Do Câncer - IBCC; Laboratório De Patologia
- Clinica de Pesquisas e Centro de Estudos Oncologia Ginecologica e Mamaria Ltda
- Complex Oncology Center Burgas; Medical Oncology Department
- Multiprofile Hospital for Active Treatment Uni Hospital; Department of medicinal oncology
- Tom Baker Cancer Centre-Calgary
- Cross Cancer Institute
- British Columbia Cancer Agency
- The Moncton Hospital
- Sault Area Hospital
- Centre Integre Universitaire de Sante et de Services Sociaux du Saguenay Lac Saint Jean
- Hopital Charles Le Moyne
- CIUSSS de l'Est-de-l'Ile-de-Montréal - Hôpital Maisonneuve-Rosemont
- CHUM
- Sir Mortimer B Davis Jewish General Hospital
- McGill University Health Center
- St-Jérome Medical Research, Inc.
- Centre Hospitalier Universitaire de Sherbrooke
- Allan Blair Cancer Centre
- CHU de Quebec-Universite Laval
- IC La Serena Research SpA
- BIOCINETIC SpA
- Centro de Estudios Clínicos SAGA SpA
- Fundacion Arturo Lopez Perez; Quimioterapia
- Oncovida - Santiago
- Patagonia Research
- Servicios Médicos URUMED SpA
- Meditek Ltda
- Icegclinic
- Medwal
- Clinica Universidad Catolica del Maule
- Sociedad de Investigaciones Medicas Ltda (SIM)
- ONCOCENTRO APYS; Oncología
- Centro de Investigaciones Clinicas Viña del Mar
- Peking University People's Hospital
- The First Hospital of Jilin University
- Jilin Cancer Hospital
- Xiangya Hospital Central South University
- Hunan Cancer Hospital
- West China Hospital, Sichuan University
- The First Affiliated Hospital, Chongqing Medical University
- The Second Affiliated Hospital of Dalian Medical University
- Fujian Provincial Cancer Hospital
- Guangdong Provincial Maternity and Child Care Cent
- Sun yat-sen University Cancer Center; Internal Medicine of Oncology
- The Second Affiliated Hospital of Zhejiang University School of Medicine
- Sir Run Run Shaw Hospital Zhejiang University
- The First Affiliated Hospital of College of Medicine, Zhejiang University
- Harbin Medical University Cancer Hospital
- Anhui Province Cancer Hospital
- Jinan Central Hospital
- Yunnan Cancer Hospital
- Linyishi Cancer Hospital
- The Third Hospital of Nanchang
- Jiangxi Cancer Hospital
- Guangxi Cancer Hospital of Guangxi Medical University
- The Second People's Hospital of Neijiang
- Fudan University Shanghai Cancer Center
- Shengjing Hospital of China Medical University
- The Fourth Hospital of Hebei Medical University
- The First Affiliated Hospital of Soochow University
- Tianjin Medical University Cancer Institute & Hospital
- Wenzhou Medical College - The First Affiliated Hospital GCP
- Union Hospital Tongji Medical College Huazhong University of Science and Technology
- Tongji Hospital Tongji Medical College Huazhong University of Science and Technology
- Hubei Cancer Hospital
- Air Force Military Medical University Xijing Hospital
- First Affiliated Hospital of Medical College of Xi'an Jiaotong University
- The First Affiliated Hospital of Xiamen University
- The Affiliated Hospital of Xuzhou Medical University
- Zhejiang Cancer Hospital
- Henan Cancer Hospital
- Hemato Oncólogos S.A
- FOSCAL
- Oncomedica S.A.
- Oncólogos Del Occidente SA
- Sociedad de Oncología y hematología del Cesar Ltda
- Consultorio Oncologico-Hospital Metropolitano Linc
- Instituto de Investigación en Ciencias Médicas S.A.
- Centro de Cáncer y Hematología
- Consultorio Oncologico-Hospital Metropolitano San
- Oncotech S.A.
- Clinical Hospital Centre Osijek
- General Hospital Pula
- University Hospital Centre Split
- General Hospital Varazdin
- Clinical Hospital Sestre Milosrdnice
- Klinicki bolnicki centar Zagreb
- Nemocnice AGEL Novy Jicin a.s.; Oddeleni radioterapie a onkologie
- Fakultni nemocnice Olomouc
- Vseobecna fakultni nemocnice v Praze
- Fakultni nemocnice v Motole
- Fakultni nemocnice Kralovske Vinohrady
- Fakultni Thomayerova Nemocnice; Onkologicke Oddeleni
- ALEXANDRIA UNI; Clinical Research Center
- Medical Technology Center for Research and Services
- Ain Shams University Hospital
- Kasr Al Ainy School of Medicine-Cairo University
- Sohag Oncology Center
- Mansoura University Hospital
- Dar ElSalam Cancer City
- Helsingin yliopistollinen keskussairaala
- Tampereen yliopistollinen sairaala
- Turun Yliopistollinen Keskussairaala
- Sas Clinique De L Europe - Amiens
- Hopital d'Argenteuil
- CHRU de Brest - Hopital Morvan
- Centre Francois Baclesse
- Institut Daniel Hollard
- Centre Hospitalier Departemental de Vendee
- Centre Jean Bernard Clinique Victor Hugo
- Centre Oscar Lambret
- CHU Dupuytren
- Hôpital Privé Clairval
- Clinique Clémentville
- Clinique Catherine de Sienne
- Institut Curie
- Hopital Universitaire Pitie Salpetriere
- Hopital Tenon
- Hopital Saint Louis
- Hôpital Européen Georges Pompidou
- Hopital privé des Côtes Armor
- EDOG - Centre Eugene Marquis Centre Regional de Lutte Contre Le Cancer - PPDS
- Centre Henri Becquerel
- Curie Saint Cloud
- Institut de Cancérologie Strasbourg Europe
- Institut Gustave Roussy
- High Technology Hospital MedCenter Ltd
- Acad. F. Todua Medical Center
- Ltd Israel-Georgia Medical Research Clinic Helsicore
- LTD Health House
- Institute of Clinical Oncology LTD
- Tbilisi Oncology Dispensary
- LTD TIM, Tbilisi Institute of Medicine
- Multiprofile Clinic Consilium Medulla
- S Khechinashvili University Clinic Ltd
- Hämatologisch/onkologische Gemeinschaftspraxis; Dres. Brudler/Heinrich/Bangerter
- Ambulantes Tumorzentrum Spandau
- Lübecker Onkologische Schwerpunktpraxis
- Marienhospital Bottrop
- Klinikum Chemnitz gGmbH
- Universitaetsklinikum Carl Gustav Carus an der TU Dresden
- UNIVERSITATSKLINIKUM ERLANGEN; Department of Gynecology and Obstetrics
- Kliniken Essen Mitte Evang. Huyssens Stiftung/Knappschaft GmbH
- Universitätsklinikum Essen
- Franziskus-Hospital Harderberg
- SRH Wald-Klinikum Gera; Brustzentrum Ostthüringen
- Mammazentrum Hamburg am Krankenhaus Jerusalem
- Gynäkologisch Onkologische Praxis Hannover
- Vincentius-Diakonissen-Kliniken gAG
- Facharztpraxis für Gynäkologie und Geburtshilfe PD Dr. med. Christian Kurbacher
- Universitätsmedizin der Johannes Gutenberg-Universität Mainz
- Klinikum Mannheim GmbH Universitätsklinikum
- Praxis fuer gynaekologische onkologie Prof. Dr. me
- Universitatsklinikum Munster
- Hämatologie und Onkologie Ravensburg / Wangen
- CaritasKlinikum Saarbruecken St Theresia
- Leopoldina Krankenhaus Schweinfurt
- Praxis fur Haematologie und Internistische Onkologie
- Henry Dunant Hospital
- University of Athens Medical School - Regional General Hospital Alexandra
- Sotiria Chest Hospital of Athens
- General Oncology Hospital Kifissias "Oi Agioi Anargyroi"
- Aretaieio Hospital of Athens
- Attikon University General Hospital
- Metropolitan General Hospital
- Metropolitan Hospital First Oncology Clinic
- Metropolitan Hospital Fourth Oncology Clinic
- University General Hospital of Heraklion
- University General Hospital of Ioannina
- University General Hospital of Larissa
- IASO Obstetrics Gynecology Clinic
- Medical Center of Athens
- Agios Loucas Clinic SA
- Olympion Clinic
- University General Hospital of Patras
- Bioclinic Thessaloniki
- Interbalkan Medical Center of Thessaloniki
- Euromedica PPDS
- Papageorgiou General Hospital of Thessaloniki
- Celan S.A.
- INTEGRA Cancer Institute
- Grupo Medico Angeles
- Oncomedica
- Clínica Médica Especializada en Hematología
- Centro Medico Integral de Cancerologia CEMIC
- Pamela Youde Nethersole Eastern Hospital; Department Of Pediatrics
- Queen Mary Hospital
- Tuen Mun Hospital
- Semmelweis Egyetem
- Tolna Megyei Balassa János Kórház
- Budapesti Uzsoki Utcai Kórház
- Debreceni Egyetem Klinikai Kozpont
- Borsod-Abauj-Zemplen Megyei Korhaz es Egyetemi Oktato Korhaz
- Szent Borbala Korhaz
- Zala Megyei Szent Rafael Korhaz
- HCG City Cancer Centre
- State Cancer Institute, Indira Gandhi Institute of Medical Sciences (IGIMS)
- Gujarat Cancer & Research Inst.
- Hemato Oncology Clinic Ahmedabad Pvt Ltd
- HCG Cancer Center
- Nirmal Hospital
- Kiran Hospital Multi Super Speciality Hospital and Research Center
- Himalaya Cancer Hospital & Research Institute
- Kailash Cancer Hospital and Research Center
- KLES Dr Prabhakar Kore Hospital and Medical Research Centre
- Sujan Surgical Cancer Hospital And Amravati Cancer Foundation
- Kolhapur Cancer Centre
- Tata Memorial Hospital
- Government Medical College
- HCG NCHRI Cancer Center
- Shalinitai Meghe Medical College and Hospital
- HCG Manavata Cancer Centre
- Chopda Medicare & Research Centre pvt. Ltd
- Apex Wellness Hospital
- Sahyadri Speciality Hospital
- Sahyadri Super Specialty Hospital Hadapsar
- Lokmanya Holistic Cancer Care and Research Center (LMRC)
- All India Institute of Medical Sciences, Bhubaneswar
- Erode Cancer Centre
- Christian Medical College-Ranipet Campus
- King George Medical University (KGMU)
- Institute of Post Graduate Medical Education and Research (IPGMER) and SSKM Hospital
- Health Point Hospital - Kolkata
- Cork University Hospital
- Bon Secours Hospital; Oncology
- St Vincents University Hospital
- St James Hospital; Cardiac Research
- Beaumont Hospital
- Galway University Hospital
- Mid- Western Regional Hospital Limerick
- Waterford Regional Hospital; Department Of Medical Oncology
- Shamir Medical Center Assaf Harofeh
- Soroka University Medical Centre
- Sheba Medical Center - PPDS
- Tel-Aviv Sourasky Medical Center
- Azienda Ospedaliera Universitaria Senese
- Azienda Ospedaliera di Rilievo Nazionale e di Alta Specialita San Giuseppe Moscati
- Istituto Nazionale per lo Studio e la Cura dei Tumori Fondazione G. Pascale
- Azienda Ospedaliero Universitaria di Bologna Policlinico S.Orsola-Malpighi
- Istituto Scientifico Romagnolo Per Lo Studio E La Cura Dei Tumori IRST - PPDS
- Arcispedale Santa Maria Nuova; Oncologia
- Fondazione Policlinico Universitario A Gemelli; Farmacia Interna
- Istituto Nazionale Tumori Regina Elena
- Ospedale Policlinico San Martino
- Ospedale San Giuseppe; Oncologia Medica
- Ospedale San Raffaele S.r.l. - PPDS
- ASST Grande Ospedale Metropolitano Niguarda - Presidio Ospedaliero Ospedale Niguarda Ca' Granda
- Istituto Clinico Humanitas
- Azienda Ospedaliero Universitaria Ospedali Riuniti
- Azienda Ospedaliera Universitaria Careggi
- Ospedale Civile - Livorno
- Azienda Ospedaliero Universitaria Pisana
- Nuovo Ospedale di Prato S. Stefano - Azienda USL Toscana Centro
- IRCCS Ospedale Sacro Cuore Don Calabria
- St. Luke's International Hospital
- Fukushima Medical University Hospital
- Hiroshima University Hospital
- National Hospital Organization Hokkaido Cancer Center
- Social Medical Corporation Hakuaikai Sagara Hospital
- Tokai University Hospital
- Kumamoto University Hospital
- Nahanishi Clinic
- National Hospital Organization Osaka National Hospital
- Osaka International Cancer Institute
- Saitama Cancer Center
- The Cancer Institute Hospital of Japanese Foundation For Cancer Research
- International Cancer Institute (ICI)
- Aga Khan University Hospital
- Chungbuk National University Hospital
- Soon Chun Hyang University Cheonan Hospital
- Yonsei University Wonju Severance Christian Hospital
- National Cancer Centre
- CHA Bundang Medical Center
- Gachon University Gil Medical Center
- Inha University Hospital
- Seoul National University Bundang Hospital
- Korea University Anam Hospital
- Seoul National University Hospital
- Severance Hospital, Yonsei University Health System
- Asan Medical Center - PPDS
- Samsung Medical Center - PPDS
- Korea University Guro Hospital
- The Catholic University of Korea Seoul St. Mary?s Hospital
- Gangnam Severance Hospital, Yonsei University Health System
- Ajou University Hospital
- Ulsan University Hosiptal
- Pauls Stradins Clinical University Hospital
- Hospital Kuala Lumpur
- University Malaya Medical Centre
- National Cancer Institute IKN
- Pantai Hospital Sungai Petani
- Sarawak General Hospital
- Beacon International Specialist Centre
- Hospital Pulau Pinang
- Centro de Investigación en Artritis y Osteoporosis - PPDS
- Office of Alma Magdalena Astorga-Ramos, MD
- Dr. José Luis González Trujillo
- Hospital Civil Fray Antonio Alcalde
- Health Pharma Professional Research
- Centro Hemato-Oncologico Privado CHOP
- Accelerium S. de R.L. de C.V.
- Hospital Universitario Dr. Jose Eleuterio Gonzalez
- Oaxaca Site Management Organization
- Centro de Investigacion Clinica de Oaxaca
- Unidad Médica Onco-Hematológica
- Clínica Integral Internacional de Oncología S de RL de CV
- Investigación Médica de Alta Especialidad
- Neurociencias Estudios Clinicos S.C.
- Merida | Investigacion Clinica
- Centro de Investigacion Medica Aguascalientes
- Centro Oncologico Alianza XXI
- Oncológico Potosino
- HAGAZIEKENHUIS; Interne Geneeskunde
- Catharina Hospital; Research Oncologie
- Maastricht University Medical Center
- Zuyderland Medisch Centrum; Trialbureau Poli Interne Geneeskunde
- Viecuri Medisch Centrum
- PHI Clinical Hospital Dr Trifun Panovski Bitola
- Acibadem Sistina Hospital
- PHI University Clinic of Radiotherapy and Oncology; Breast malignancy
- Hospital Nacional Daniel A Carrion
- Hospital Militar Central
- Hospital Central Fuerza Aerea Del Peru
- Clínica Santa Beatriz
- Oncologia S.A.C. - Instituto Peruano de Oncología & Radioterapia
- Oncosalud Sac; Oncología
- Instituto Nacional de Enfermedades Neoplasicas
- Clinica Peruana Americana
- Dr Pablo O Torre Memorial Hospital
- Baguio General Hospital and Medical Center
- Saint Louis University Hospital of Sacred Heart
- Metro Davao Medical and Research Center
- St. Paul's Hospital
- University of Santo Tomas Hospital; Pharmacy
- Cardinal Santos Medical Center; Department of Internal Medicine, Section of Endocrinology
- The Medical City; Oncology
- East Avenue Medical Center; Breast Care Center
- St. Luke's Medical Center - Quezon City
- Centrum Onkologii im. Prof. F. Lukaszczyka w Bydgoszczy
- Szpital Morski Im. Pck; Oncology & Radiotherapy Dept
- Narodowy Instytut Onkologii im. M.Sk?odowskiej-Curie - Pa?stwowy Instytut Badawczy Oddzia? Gliwice
- Regionalny Szpital Specjalistyczny im. W. Bieganskiego; Oddzia? Onkologii Klinicznej
- Centrum Terapii Wspolczesnej
- Centrum Onkologii Ziemi LUBELSKIEJ im. Sw Jana z Dukli, I oddz. Chemioterapii
- Centrum Medyczne Pratia Poznan
- Narodowy Instytut Onkologii - Panstwowy Instytut Badawczy, Oddzia? w Krakowie
- Narodowy Instytut Onkologii im. Marii Sk?odowskiej-Curie - Pa?stwowy Instytut Badawczy
- Hospital Senhora da Oliveira ? Guimaraes, E.P.E
- Champalimaud Cancer Center
- Hospital da Luz
- Centro Hospitalar Lisboa Norte, E.P.E. ? Hospital de Santa Maria; Servicos Farmaceuticos
- Instituto Português de Oncologia de Lisboa Francisco Gentil, E.P.E.
- Hospital Beatriz Angelo
- Centro Hospitalar do Porto ? Hospital de Santo António; Oncologia
- Instituto Portugues de Oncologia Do Porto Francisco Gentil Epe
- Centro Hospitalar de Vila Nova de Gaia / Espinho E.P.E
- Centro Hospitalar Trás Os Montes E Alto Douro EPE
- Spitalul Clinic de Obstetrica si Ginecologie Filantropia; Sectorul 1 BUCURE?TI
- Prof Dr I Chiricuta Institute of Oncology; Oncology Department
- Medisprof SRL
- Onco Clinic Consult SA
- Oncology Center Sf. Nectarie
- Institutul Regional de Oncologie Iasi
- Timisoara Emergency County Clinical Hospital
- Institute for Oncology and Radiology of Serbia
- University Hospital Medical Center Bezanijska kosa
- Health Center Kladovo
- Clinical Center Kragujevac
- Clinical Center Nis
- Oncology Institute of Vojvodina
- General Hospital Djordje Joanovic - Zrenjanin
- Univerzitna nemocnica s poliklinikou Milosrdni bratia spol s r o
- Onkologicky ustav sv. Alzbety, s.r.o.
- Narodny onkologicky ustav
- Vychodoslovensky onkologicky ustav
- Institute of Oncology Ljubljana
- Cape Town Oncology Trials
- Cancercare Rondebosch Oncology
- WITS Clinical Research Site PPDS
- Sandton Oncology Medical Group (Pty) Ltd
- Excellentis Clinical Trial Consultants; Clinical Research
- Medical Oncology Centre of Rosebank; Oncology
- Southern Cross Research South Africa (PTY) LTD
- Langenhoven Drive Oncology Centre
- Wilgers Oncology Centre
- Eastleigh Breast Care Centre
- Hospital General Universitario de Elche
- ICO Badalona-H.U. Germans Trias i Pujol
- ALTHAIA Xarxa Assistencial de Manresa
- Corporacio Sanitaria Parc Tauli
- Hospital HM Nuestra Señora de la Esperanza
- Hospital de Jerez
- Consorcio Hospitalario Provincial de Castellon
- Hospital Universitario Reina Sofia; Servicio de Farmacia
- Hospital Universitario de Donostia
- Hospital Universitario Son Espases
- Hospital Son Llatzer
- Hospital Universitario A Coruña
- CHUS H Clinico U de Santiago
- Hospital Universitario Insular de Gran Canaria
- Hospital Universitari Arnau de Vilanova
- Hospital Universitario Fundación Alcorcón
- Hospital Universitario Puerta de Hierro - Majadahonda
- Complejo Hospitalario de Navarra; Servicio de Farmacia
- CHUVI ? H.U. Alvaro Cunqueiro
- Hospital Nuestra Senora de Valme
- Hospital Universitario Virgen Macarena
- Hospital Universitari Sant Joan de Reus
- Hospital Universitario de Canarias
- Hospital Universitario Basurto
- Complejo Hospitalario Universitario de Albacete
- Hospital General Universitario de Alicante
- Hospital Universitario San Juan
- Hospital Nuestra Señora de Sonsoles
- Hospital del Mar
- Clinica Tres Torres
- Hospital de la Santa Creu i Sant Pau
- Hospital Universitario Quiron Dexeus
- Hospital Universitari Vall d'Hebron
- Hospital Clinic de Barcelona
- Hospital de San Pedro de Alcantara
- Hospital Puerta del Mar
- Institut Catala d'Oncologia Girona
- Hospital Universitario Clínico San Cecilio
- Hospital Universitario Virgen de Las Nieves
- Hospital Universitario Juan Ramon Jimenez
- Hospital Universitario de Jaen
- Hospital General Universitario Gregorio Marañon
- Hospital Universitario La Paz
- Clinica Universidad Navarra; Servicio de Farmacia
- Hospital Universitario Infanta Leonor
- Centro Oncologioco MD Anderson Internacional; Servicio de Farmacia
- Hospital Universitario Ramon y Cajal
- Hospital Clinico San Carlos
- Hospital Universitario Fundacion Jimenez Diaz.
- Hospital Ruber Internacional
- Hospital Universitario 12 De Octubre
- Hospital Universitario HM Sanchinarro ? CIOCC; Farmacia - Ensayos Clínicos
- Hospital Universitario de Fuenlabrada
- Hospital Universitario Virgen de la Victoria
- Hospital General Universitario Morales Meseguer; Servicio de Neurología
- Hospital Universitario Virgen de La Arrixaca
- Hospital Universitario Virgen del Rocío
- Fundacion Instituto Valenciano de Oncologia (IVO)
- Hospital Clinico Universitario de Valencia
- Consorcio Hospital General Universitario de Valencia
- Hospital Universitari i Politecnic La Fe de Valencia
- Hospital Clinico Universitario de Valladolid; Servicio de Oncologia
- Hospital Universitario Miguel Servet
- Länssjukhuset Ryhov
- Södersjukhuset
- Sundsvalls sjukhus
- Akademiska Sjukhuset
- Västmanlands sjukhus Västerås
- Tumorzentrum Aarau
- Kantonsspital Baden
- Universitätsspital Basel
- Universitätsspital Bern; Departement Herz & Gefässe
- Hirslanden Salem-Spital
- Kantonsspital Graubuenden
- Luzerner Kantonsspital LUKS; Studienzentrale Onkologie
- Hirslanden Klinik St. Anna Brustzentrum/Chirurgie
- Kantonsspital St. Gallen
- Spital STS AG Thun - Berner Oberland ; Onkologie Zentrum
- Kantonsspital Winterthur Medizin Pneumologie
- Brust-Zentrum Zürich AG Seefeldstrasse 214 Zürich
- Koo Foundation Sun Yat-Sen Cancer Center
- Changhua Christian Medical Foundation Changhua Christian Hospital
- Hsin-Chu Branch of National Taiwan University Hospital
- Kaohsiung Medical University Chung-Ho Memorial Hospital
- Taipei Medical University Shuang Ho Hospital
- China Medical University Hospital
- National Cheng Kung University Hospital
- Chi Mei Medical Cente
- Taipei Veterans General Hospital
- National Taiwan University Hospital
- Mackay Memorial Hospital - Taipei Branch
- Tri-Service General Hospital
- Chang Gung Memorial Hospital - Linkou
- Taichung Veterans General Hospital
- Chulalongkorn Hospital; Medical Oncology
- Ramathibodi Hospital
- Siriraj Hospital, Mahidol University
- Hacettepe Universitesi Tip Fakultesi Hastanesi
- Ankara City Hospital; Oncology
- Akdeniz University Medical Faculty
- Trakya University Medical Faculty
- Istanbul University Cerrahpasa Medical Faculty Hospital; Klinik Arast?rma Merkezi
- T.C. Saglik Bakanligi Goztepe Prof. Dr. Suleyman Yalcin City Hospital
- Izmir Medical Point Hospital
- Katip Celebi University- Izmir Ataturk Egitim ve Arastirma Hastanesi
- Kocaeli Universitesi Tip Fakultesi Arastirma ve Uygulama Hastanesi
- Ondokuz Mayis Universitesi Tip Fakultesi Hastanesi
- Acibadem Maslak Hastanesi Büyükdere
- Baskent Universitesi - Adana Uygulama Ve Arastirma Merkezi
- Acibadem Adana Hospital, Oncology Department
- Dr. Abdurrahman Yurtaslan Ankara Onkoloji Egitim ve Arastirma Hastanesi
- Acibadem Altunizade Hospital
- St Francis Hospital Nsambya
- Uganda Cancer Institute
- SI Institute for general and urgent surgery n.a. V.T.Zaitseva of NAMS of Ukraine
- Municipal Non-profit Enterprise Odessa Regional Clinical Hospital of Odessa Regional Council
- Communal Non-Profit Enterprise Chernihiv Medical Center of Modern Oncology of CRC
- Regional Municipal Non-Commercial Enterprise Bukovynian Clinical Oncology Center
- Clinic Verum Expert LLC
- Communal Nonprofit Enterprise Kyiv City Clinical Oncological Center
- Medical Clinical Research Center of Medical Center LLC Health Clinic
- Kyiv Regional Oncological Dispensary
- Royal Sussex County Hospital
- Royal Cornwall Hospital; Dept of Clinical Oncology
- Leicester Royal Infirmary
- Barts and The London School of Medicine and Dentistry - Barts Cancer Institute (BCI)-CECM
- University College London Hospitals; Clinical Research Facility
- The Christie NHS Foundation Trust
- Nottingham City Hospital
- Royal Preston Hospital
Arms of the Study
Arm 1
Arm 2
Arm Type
Experimental
Active Comparator
Arm Label
Arm A: Giredestrant
Arm B: Endocrine Therapy of Physician's Choice
Arm Description
Outcomes
Primary Outcome Measures
Invasive Disease-Free Survival (IDFS), Excluding Second Primary Non-Breast Cancers
Secondary Outcome Measures
Overall Survival
Invasive Disease-Free Survival (IDFS), Including Second Primary Non-Breast Cancers
Disease-Free Survival (DFS)
Distant Recurrence-Free Interval (DRFI)
Locoregional Recurrence-Free Interval (LRRFI)
Mean Physical Functioning Scale Score at Specified Timepoints, Assessed Using the European Organisation for the Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30)
Change from Baseline in the Mean Physical Functioning Scale Score at Specified Timepoints, Assessed Using the EORTC QLQ-C30
Mean Role Functioning Scale Score at Specified Timepoints, Assessed Using the EORTC QLQ-C30
Change from Baseline in the Mean Role Functioning Scale Score at Specified Timepoints, Assessed Using the EORTC QLQ-C30
Mean Global Health Status/Quality of Life (QoL) Scale Score at Specified Timepoints, Assessed Using the EORTC QLQ-C30
Change from Baseline in the Mean Global Health Status/Quality of Life (QoL) Scale Score at Specified Timepoints, Assessed Using the EORTC QLQ-C30
Change from Baseline in the EQ 5D-5L Index-Based Score at Specified Timepoints
Change from Baseline in the EQ 5D-5L Visual Analogue Scale (VAS) Score at Specified Timepoints
Incidence and Severity of Adverse Events, with Severity Determined According to National Cancer Institute Common Terminology Criteria for Adverse Events, version 5.0 (NCI-CTCAE v5.0)
Plasma Concentrations of Giredestrant at Specified Timepoints
Full Information
1. Study Identification
Unique Protocol Identification Number
NCT04961996
Brief Title
A Study Evaluating the Efficacy and Safety of Adjuvant Giredestrant Compared With Physician's Choice of Adjuvant Endocrine Monotherapy in Participants With Estrogen Receptor-Positive, HER2-Negative Early Breast Cancer (lidERA Breast Cancer)
Official Title
A Phase III, Randomized, Open-Label, Multicenter Study Evaluating the Efficacy and Safety of Adjuvant Giredestrant Compared With Physician's Choice of Adjuvant Endocrine Monotherapy in Patients With Estrogen Receptor-Positive, HER2-Negative Early Breast Cancer
Study Type
Interventional
2. Study Status
Record Verification Date
October 2023
Overall Recruitment Status
Active, not recruiting
Study Start Date
August 27, 2021 (Actual)
Primary Completion Date
December 19, 2025 (Anticipated)
Study Completion Date
November 21, 2033 (Anticipated)
3. Sponsor/Collaborators
Responsible Party, by Official Title
Sponsor
Name of the Sponsor
Hoffmann-La Roche
4. Oversight
Studies a U.S. FDA-regulated Drug Product
Yes
Studies a U.S. FDA-regulated Device Product
No
Data Monitoring Committee
Yes
5. Study Description
Brief Summary
This is a Phase III, global, randomized, open-label, multicenter, study evaluating the efficacy and safety of adjuvant giredestrant compared with endocrine therapy of physician's choice in participants with medium- and high-risk Stage I-III histologically confirmed estrogen receptor (ER)-positive and human epidermal growth factor receptor 2 (HER2)-negative early breast cancer.
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Early Breast Cancer
7. Study Design
Primary Purpose
Treatment
Study Phase
Phase 3
Interventional Study Model
Parallel Assignment
Masking
None (Open Label)
Allocation
Randomized
Enrollment
4100 (Anticipated)
8. Arms, Groups, and Interventions
Arm Title
Arm A: Giredestrant
Arm Type
Experimental
Arm Title
Arm B: Endocrine Therapy of Physician's Choice
Arm Type
Active Comparator
Intervention Type
Drug
Intervention Name(s)
Giredestrant
Other Intervention Name(s)
GDC-9545, RO7197597, RG6171
Intervention Description
Giredestrant 30 milligrams (mg) will be administered orally once a day (QD) on Days 1-28 of each 28-day cycle for 5 years or until disease recurrence or unacceptable toxicity (whichever occurs first).
Intervention Type
Drug
Intervention Name(s)
Endocrine Therapy of Physician's Choice
Intervention Description
The endocrine therapy of physician's choice (TPC) is limited to tamoxifen or one of the specified third generation aromatase inhibitors: letrozole, anastrozole, or exemestane. Participants will receive TPC daily on Days 1-28 of each 28-day cycle for 5 years or until disease recurrence or unacceptable toxicity (whichever occurs first). Continuing TPC after 5 years is at the discretion of the investigator and per local standard of care. Dose administration of TPC should be performed in accordance with the local prescribing information for the respective product.
Intervention Type
Drug
Intervention Name(s)
LHRH Agonist
Intervention Description
A luteinizing hormone-releasing hormone (LHRH) agonist will be administered to male participants and premenopausal/perimenopausal participants according to local prescribing information. The investigator may determine and supply the appropriate LHRH agonist locally approved for use in breast cancer.
Primary Outcome Measure Information:
Title
Invasive Disease-Free Survival (IDFS), Excluding Second Primary Non-Breast Cancers
Time Frame
From randomization to first occurrence of an IDFS event (up to 10 years)
Secondary Outcome Measure Information:
Title
Overall Survival
Time Frame
From randomization to death from any cause (up to 10 years)
Title
Invasive Disease-Free Survival (IDFS), Including Second Primary Non-Breast Cancers
Time Frame
From randomization to first occurrence of an IDFS event (up to 10 years)
Title
Disease-Free Survival (DFS)
Time Frame
From randomization to first occurrence of a DFS event (up to 10 years)
Title
Distant Recurrence-Free Interval (DRFI)
Time Frame
From randomization to first occurrence of a DFRI event (up to 10 years)
Title
Locoregional Recurrence-Free Interval (LRRFI)
Time Frame
From randomization to first occurrence of a LRRFI event (up to 10 years)
Title
Mean Physical Functioning Scale Score at Specified Timepoints, Assessed Using the European Organisation for the Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30)
Time Frame
Baseline (Cycle 1) and Cycles 3, 6, 9, 12, 15, 18, 21, 24, 30, 36, 42, 48, 54, and 60 (1 cycle is 28 days) of treatment, once every 6 months during the first 2 years of post-treatment follow-up and annually for 3 years thereafter (up to 10 years)
Title
Change from Baseline in the Mean Physical Functioning Scale Score at Specified Timepoints, Assessed Using the EORTC QLQ-C30
Time Frame
Baseline (Cycle 1) and Cycles 3, 6, 9, 12, 15, 18, 21, 24, 30, 36, 42, 48, 54, and 60 (1 cycle is 28 days) of treatment, once every 6 months during the first 2 years of post-treatment follow-up and annually for 3 years thereafter (up to 10 years)
Title
Mean Role Functioning Scale Score at Specified Timepoints, Assessed Using the EORTC QLQ-C30
Time Frame
Baseline (Cycle 1) and Cycles 3, 6, 9, 12, 15, 18, 21, 24, 30, 36, 42, 48, 54, and 60 (1 cycle is 28 days) of treatment, once every 6 months during the first 2 years of post-treatment follow-up and annually for 3 years thereafter (up to 10 years)
Title
Change from Baseline in the Mean Role Functioning Scale Score at Specified Timepoints, Assessed Using the EORTC QLQ-C30
Time Frame
Baseline (Cycle 1) and Cycles 3, 6, 9, 12, 15, 18, 21, 24, 30, 36, 42, 48, 54, and 60 (1 cycle is 28 days) of treatment, once every 6 months during the first 2 years of post-treatment follow-up and annually for 3 years thereafter (up to 10 years)
Title
Mean Global Health Status/Quality of Life (QoL) Scale Score at Specified Timepoints, Assessed Using the EORTC QLQ-C30
Time Frame
Baseline (Cycle 1) and Cycles 3, 6, 9, 12, 15, 18, 21, 24, 30, 36, 42, 48, 54, and 60 (1 cycle is 28 days) of treatment, once every 6 months during the first 2 years of post-treatment follow-up and annually for 3 years thereafter (up to 10 years)
Title
Change from Baseline in the Mean Global Health Status/Quality of Life (QoL) Scale Score at Specified Timepoints, Assessed Using the EORTC QLQ-C30
Time Frame
Baseline (Cycle 1) and Cycles 3, 6, 9, 12, 15, 18, 21, 24, 30, 36, 42, 48, 54, and 60 (1 cycle is 28 days) of treatment, once every 6 months during the first 2 years of post-treatment follow-up and annually for 3 years thereafter (up to 10 years)
Title
Change from Baseline in the EQ 5D-5L Index-Based Score at Specified Timepoints
Time Frame
Baseline (Cycle 1) and Cycles 3, 6, 9, 12, 15, 18, 21, 24, 30, 36, 42, 48, 54, and 60 (1 cycle is 28 days) of treatment, once every 6 months during the first 2 years of post-treatment follow-up and annually for 3 years thereafter (up to 10 years)
Title
Change from Baseline in the EQ 5D-5L Visual Analogue Scale (VAS) Score at Specified Timepoints
Time Frame
Baseline (Cycle 1) and Cycles 3, 6, 9, 12, 15, 18, 21, 24, 30, 36, 42, 48, 54, and 60 (1 cycle is 28 days) of treatment, once every 6 months during the first 2 years of post-treatment follow-up and annually for 3 years thereafter (up to 10 years)
Title
Incidence and Severity of Adverse Events, with Severity Determined According to National Cancer Institute Common Terminology Criteria for Adverse Events, version 5.0 (NCI-CTCAE v5.0)
Time Frame
From start of treatment until 28 days after the final dose of study treatment (up to 5 years)
Title
Plasma Concentrations of Giredestrant at Specified Timepoints
Time Frame
Predose and 3-4 hours postdose on Day 1 of Cycles 1 and 2, and predose on Day 1 of Cycles 3 and 6 (1 cycle is 28 days)
10. Eligibility
Sex
All
Minimum Age & Unit of Time
18 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria:
Documented estrogen receptor (ER)-positive and HER2-negative breast tumor, as assessed locally on a primary disease specimen
Participants who have multicentric (the presence of two of more tumor foci within different quadrants of the same breast) and/or multifocal (the presence of two or more tumor foci within a single quadrant of the breast) breast cancer are also eligible if all examined tumors meet pathologic criteria for ER positivity and HER2 negativity
Participants must have undergone definitive surgery of their primary breast tumor(s) and axillary lymph nodes (axillary lymph node dissection [ALND] and/or sentinel lymph node biopsy [SLNB])
Participants who received or will be receiving adjuvant chemotherapy must have completed adjuvant chemotherapy prior to randomization. Participants may also have received neoadjuvant chemotherapy. A washout period of at least 21 days is required between last adjuvant chemotherapy dose and randomization.
Resolution of all acute toxic effects of prior anti-cancer therapy or surgical procedures to NCI CTCAE v5.0 Grade 1 or better (except alopecia, Grade ≤2 peripheral neuropathy, arthralgia or other toxicities not considered a safety risk for the participant per the investigator's judgment)
Participants have received (neo)adjuvant chemotherapy and/or had surgery and had no prior endocrine therapy are eligible, provided that they are enrolled within 12 months following definitive breast cancer surgery
Participants who have confirmed availability of an untreated primary breast tumor tissue specimen suitable for biomarker testing (i.e., representative archived formalin-fixed, paraffin-embedded [FFPE] tissue block [preferred] or 15-20 slides containing unstained, freshly cut, serial sections), with associated de-identified pathology report is required. Although 15-20 slides are preferred, if only 10-14 slides are available, the individual may still be eligible for the study.
Participants with node-positive and node-negative disease are eligible provided they meet additional risk criteria as defined in the protocol
Eastern Cooperative Oncology Group (ECOG) Performance Status 0, 1, or 2
Able and willing to swallow, retain, and absorb oral medication
Adequate organ function
Exclusion Criteria:
Pregnant or breastfeeding, or intending to become pregnant during the study or within 10 days after the final dose of giredestrant, or within the time period specified per local prescribing guidelines after the final dose of the endocrine therapy of physician's choice
Received treatment with investigational therapy within 28 days prior to initiation of study treatment or is currently enrolled in any other type of medical research judged by the sponsor not to be scientifically or medically compatible with this study
Receiving or planning to receive a CDK4/6 inhibitor as (neo)adjuvant therapy. A short course of up to 12 weeks of neoadjuvant or adjuvant treatment with CDK4/6 inhibitor therapy prior to randomization is allowed.
Active cardiac disease or history of cardiac dysfunction
Diagnosed with Stage IV breast cancer
A history of any prior (ipsilateral and/or contralateral) invasive breast cancer or ductal carcinoma in situ (DCIS). Participants with a history of contralateral DCIS treated by only local regional therapy at any time may be eligible.
A history of any other malignancy within 3 years prior to screening, except for appropriately treated carcinoma in situ of the cervix, nonmelanoma skin carcinoma, or Stage I uterine cancer
Any prior endocrine treatment with selective ER modulators (e.g., tamoxifen), degraders, or aromatase inhibitors. A short course of neoadjuvant or adjuvant endocrine therapy (up to 12 weeks) is allowed.
Clinically significant liver disease consistent with Child-Pugh Class B or C, including active hepatitis (e.g., hepatitis B virus [HBV] or hepatitis C virus [HCV]), current alcohol abuse, cirrhosis, or positive test for viral hepatitis
Treatment with strong CYP3A4 inhibitors or inducers within 14 days or 5 drug elimination half-lives (whichever is longer) prior to initiation of study treatment
Known allergy or hypersensitivity to any of the study drugs or any of their excipients
Pre- and perimenopausal participants or male participants who have a known hypersensitivity to LHRH agonists
A documented history of hemorrhagic diathesis, coagulopathy, or thromboembolism
Renal dysfunction that requires dialysis
A major surgical procedure unrelated to breast cancer within 28 days prior to randomization
A serious infection requiring oral or IV antibiotics within 14 days prior to screening or other clinically significant infection (e.g., COVID-19) within 14 days prior to screening
Any serious medical condition or abnormality in clinical laboratory tests that, in the investigator's judgment, precludes an individual's safe participation in and completion of the study
Unable or unwilling to comply with the requirements of the protocol in the opinion of the investigator
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Clinical Trials
Organizational Affiliation
Hoffmann-La Roche
Official's Role
Study Director
Facility Information:
Facility Name
Southern Cancer Center
City
Daphne
State/Province
Alabama
ZIP/Postal Code
36526
Country
United States
Facility Name
CBCC Global Research Inc., at Comprehensive Blood and Cancer Center
City
Bakersfield
State/Province
California
ZIP/Postal Code
93309
Country
United States
Facility Name
Arrowhead Regional Medical Center
City
Colton
State/Province
California
ZIP/Postal Code
92324
Country
United States
Facility Name
Cancer and Blood Specialty Clinic
City
Fountain Valley
State/Province
California
ZIP/Postal Code
92708
Country
United States
Facility Name
Long Beach Memorial Medical Center
City
Fountain Valley
State/Province
California
ZIP/Postal Code
92708
Country
United States
Facility Name
Keck Medicine of USC ? Newport Beach
City
Newport Beach
State/Province
California
ZIP/Postal Code
92663-4121
Country
United States
Facility Name
The Center for Cancer Prevention and Treatment at St.Joseph Hospital of Orange
City
Orange
State/Province
California
ZIP/Postal Code
92868
Country
United States
Facility Name
Stanford University Medical Center
City
Palo Alto
State/Province
California
ZIP/Postal Code
94304
Country
United States
Facility Name
Kaiser Permanente - Roseville
City
Roseville
State/Province
California
ZIP/Postal Code
95661
Country
United States
Facility Name
Kaiser Permanente - San Diego
City
San Diego
State/Province
California
ZIP/Postal Code
92120
Country
United States
Facility Name
Kaiser Permanente - San Francisco (2238 Geary)
City
San Francisco
State/Province
California
ZIP/Postal Code
94115
Country
United States
Facility Name
Stanford Cancer Center South Bay
City
San Jose
State/Province
California
ZIP/Postal Code
95124
Country
United States
Facility Name
Sansum Clinic
City
Santa Barbara
State/Province
California
ZIP/Postal Code
93105
Country
United States
Facility Name
Kaiser Permanente - Santa Clara
City
Santa Clara
State/Province
California
ZIP/Postal Code
95051
Country
United States
Facility Name
UCLA Hematology/Oncology
City
Santa Monica
State/Province
California
ZIP/Postal Code
90404
Country
United States
Facility Name
St Joseph Heritage Healthcare
City
Santa Rosa
State/Province
California
ZIP/Postal Code
95403
Country
United States
Facility Name
Torrance Memorial Physician Network/Cancer Care
City
Torrance
State/Province
California
ZIP/Postal Code
90505
Country
United States
Facility Name
Kaiser Permanente - Vallejo
City
Vallejo
State/Province
California
ZIP/Postal Code
94589
Country
United States
Facility Name
Valley Breast Care and Women's Health Center
City
Van Nuys
State/Province
California
ZIP/Postal Code
91405
Country
United States
Facility Name
Rocky Mountain Cancer Centers (Longmont) - USOR
City
Longmont
State/Province
Colorado
ZIP/Postal Code
80501
Country
United States
Facility Name
Stamford Hospital; Clincal Trials Office - 1st Fl - Bennett Cancer Cente
City
Stamford
State/Province
Connecticut
ZIP/Postal Code
06902
Country
United States
Facility Name
University of Florida; UF Health Shands Cancer Hospital
City
Gainesville
State/Province
Florida
ZIP/Postal Code
32608
Country
United States
Facility Name
Memorial Healthcare System - Memorial Regional Hospital
City
Hollywood
State/Province
Florida
ZIP/Postal Code
33021
Country
United States
Facility Name
Baptist - MD Anderson Cancer Center
City
Jacksonville
State/Province
Florida
ZIP/Postal Code
32207
Country
United States
Facility Name
Mount Sinai Comprehensive Cancer Center
City
Miami Beach
State/Province
Florida
ZIP/Postal Code
33140
Country
United States
Facility Name
Miami Cancer Institute of Baptist Health, Inc.
City
Miami
State/Province
Florida
ZIP/Postal Code
33176
Country
United States
Facility Name
Orlando Health Cancer Institute
City
Orlando
State/Province
Florida
ZIP/Postal Code
32806
Country
United States
Facility Name
Miami Cancer Institute-Plantation
City
Plantation
State/Province
Florida
ZIP/Postal Code
33324
Country
United States
Facility Name
Memorial Health University Cancer Center
City
Savannah
State/Province
Georgia
ZIP/Postal Code
31404
Country
United States
Facility Name
University of Illinois at Chicago
City
Chicago
State/Province
Illinois
ZIP/Postal Code
60612
Country
United States
Facility Name
University of Chicago Hospital
City
Chicago
State/Province
Illinois
ZIP/Postal Code
60637
Country
United States
Facility Name
Elmhurst Cancer Center
City
Elmhurst
State/Province
Illinois
ZIP/Postal Code
60126
Country
United States
Facility Name
Joliet Oncology Hematology Associates, Ltd.
City
Joliet
State/Province
Illinois
ZIP/Postal Code
60435
Country
United States
Facility Name
Edward Cancer Center Naperville
City
Naperville
State/Province
Illinois
ZIP/Postal Code
60540
Country
United States
Facility Name
Edward Cancer Center Plainfield
City
Plainfield
State/Province
Illinois
ZIP/Postal Code
60585
Country
United States
Facility Name
Oncology Associates at Mercy Medical Center
City
Cedar Rapids
State/Province
Iowa
ZIP/Postal Code
52403
Country
United States
Facility Name
University of Iowa
City
Iowa City
State/Province
Iowa
ZIP/Postal Code
52242-1086
Country
United States
Facility Name
Cancer Center of Kansas - Kingman
City
Kingman
State/Province
Kansas
ZIP/Postal Code
67068
Country
United States
Facility Name
Lahey Clinic Med Ctr
City
Lexington
State/Province
Kentucky
ZIP/Postal Code
02421
Country
United States
Facility Name
University of Kentucky; Markey Cancer Center
City
Lexington
State/Province
Kentucky
ZIP/Postal Code
40536
Country
United States
Facility Name
Norton Cancer Institute - MDC
City
Louisville
State/Province
Kentucky
ZIP/Postal Code
40202
Country
United States
Facility Name
Hematology/Oncology Clinic, LLP
City
Baton Rouge
State/Province
Louisiana
ZIP/Postal Code
70809
Country
United States
Facility Name
University Medical Center New Orleans
City
New Orleans
State/Province
Louisiana
ZIP/Postal Code
70112
Country
United States
Facility Name
UPMC Western Maryland - Schwab Family Cancer Center
City
Cumberland
State/Province
Maryland
ZIP/Postal Code
21502
Country
United States
Facility Name
University of Maryland; St. Joseph Medical Center
City
Towson
State/Province
Maryland
ZIP/Postal Code
21204
Country
United States
Facility Name
Massachusetts General Hospital; Lurie Center for Autism
City
Lexington
State/Province
Massachusetts
ZIP/Postal Code
02421
Country
United States
Facility Name
University Of Michigan
City
Ann Arbor
State/Province
Michigan
ZIP/Postal Code
48109
Country
United States
Facility Name
Barbara Ann Karmanos Cancer Institute
City
Detroit
State/Province
Michigan
ZIP/Postal Code
48201
Country
United States
Facility Name
Metro-Minnesota Community Oncology Research Consortium
City
Saint Louis Park
State/Province
Minnesota
ZIP/Postal Code
55416
Country
United States
Facility Name
University of Missouri-Columbia; Ellis Fischel Cancer Center
City
Kansas City
State/Province
Missouri
ZIP/Postal Code
64108
Country
United States
Facility Name
St. Vincent Frontier Cancer Center
City
Billings
State/Province
Montana
ZIP/Postal Code
59102
Country
United States
Facility Name
Nebraska Cancer Specialists
City
Omaha
State/Province
Nebraska
ZIP/Postal Code
68130-2042
Country
United States
Facility Name
University of Nebraska Medical Center
City
Omaha
State/Province
Nebraska
ZIP/Postal Code
68198-0600
Country
United States
Facility Name
Comprehensive Cancer Centers of Nevada
City
Las Vegas
State/Province
Nevada
ZIP/Postal Code
89128
Country
United States
Facility Name
MD Anderson Cancer Center at Cooper
City
Camden
State/Province
New Jersey
ZIP/Postal Code
08103
Country
United States
Facility Name
Hunterdon Hematology Oncology
City
Flemington
State/Province
New Jersey
ZIP/Postal Code
08822
Country
United States
Facility Name
Rutgers Cancer Institute of New Jersey
City
New Brunswick
State/Province
New Jersey
ZIP/Postal Code
08901
Country
United States
Facility Name
Roswell Park Cancer Institute
City
Buffalo
State/Province
New York
ZIP/Postal Code
14263
Country
United States
Facility Name
Queens Hospital Cancer Center
City
Jamaica
State/Province
New York
ZIP/Postal Code
11432
Country
United States
Facility Name
NYU Winthrop Hospital
City
Mineola
State/Province
New York
ZIP/Postal Code
11501
Country
United States
Facility Name
New York University Cancer Cen
City
New York
State/Province
New York
ZIP/Postal Code
10016
Country
United States
Facility Name
Stony Brook Univ Cancer Ctr
City
Stony Brook
State/Province
New York
ZIP/Postal Code
11794
Country
United States
Facility Name
Messino Cancer Centers
City
Asheville
State/Province
North Carolina
ZIP/Postal Code
28806
Country
United States
Facility Name
Levine Cancer Institute
City
Charlotte
State/Province
North Carolina
ZIP/Postal Code
28204
Country
United States
Facility Name
First Health of the Carolinas
City
Pinehurst
State/Province
North Carolina
ZIP/Postal Code
28374
Country
United States
Facility Name
Rex Cancer Center
City
Raleigh
State/Province
North Carolina
ZIP/Postal Code
27606
Country
United States
Facility Name
UNC Cancer Care at Nash
City
Rocky Mount
State/Province
North Carolina
ZIP/Postal Code
27804
Country
United States
Facility Name
Wake Forest Baptist Medical Center
City
Winston-Salem
State/Province
North Carolina
ZIP/Postal Code
27157
Country
United States
Facility Name
Aultman Hospital
City
Canton
State/Province
Ohio
ZIP/Postal Code
44710
Country
United States
Facility Name
Oncology Hematology Care Inc
City
Cincinnati
State/Province
Ohio
ZIP/Postal Code
45242
Country
United States
Facility Name
University Hospitals Cleveland Medical Center
City
Cleveland
State/Province
Ohio
ZIP/Postal Code
44106
Country
United States
Facility Name
Cleveland Clinic; Taussig Cancer Institute
City
Cleveland
State/Province
Ohio
ZIP/Postal Code
44195
Country
United States
Facility Name
Columbus NCORP
City
Columbus
State/Province
Ohio
ZIP/Postal Code
43125
Country
United States
Facility Name
Stefanie Spielman Comprehensive Breast Center
City
Columbus
State/Province
Ohio
ZIP/Postal Code
43212
Country
United States
Facility Name
SCRI Mark H. Zangmeister Center
City
Columbus
State/Province
Ohio
ZIP/Postal Code
43219
Country
United States
Facility Name
Kaiser Permanente-Northwest Region
City
Portland
State/Province
Oregon
ZIP/Postal Code
97227
Country
United States
Facility Name
Oncology Associates of Oregon, P.C.; Willamette Valley Cancer Institute
City
Springfield
State/Province
Oregon
ZIP/Postal Code
97477
Country
United States
Facility Name
Northwest Cancer Specialists, P.C.
City
Tigard
State/Province
Oregon
ZIP/Postal Code
97223
Country
United States
Facility Name
Pinnacle Health
City
Harrisburg
State/Province
Pennsylvania
ZIP/Postal Code
17110
Country
United States
Facility Name
Penn State Univ. Milton S. Hershey Medical Center; Department of Investigational Drug Services
City
Hershey
State/Province
Pennsylvania
ZIP/Postal Code
17033
Country
United States
Facility Name
Allegheny Cancer Center
City
Pittsburgh
State/Province
Pennsylvania
ZIP/Postal Code
15212
Country
United States
Facility Name
University of Pittsburgh Medical Center; Division of Hematology-Oncology
City
Pittsburgh
State/Province
Pennsylvania
ZIP/Postal Code
15232
Country
United States
Facility Name
Reading Hospital
City
West Reading
State/Province
Pennsylvania
ZIP/Postal Code
19611
Country
United States
Facility Name
UPMC Williamsport, Divine Providence Campus
City
Williamsport
State/Province
Pennsylvania
ZIP/Postal Code
17701
Country
United States
Facility Name
Women & Infants Hospital
City
Providence
State/Province
Rhode Island
ZIP/Postal Code
02905
Country
United States
Facility Name
Avera Cancer Institute
City
Sioux Falls
State/Province
South Dakota
ZIP/Postal Code
57105
Country
United States
Facility Name
West Cancer Center & Research Institute
City
Germantown
State/Province
Tennessee
ZIP/Postal Code
38138-1762
Country
United States
Facility Name
Tennessee Oncology NASH - SCRI - PPDS
City
Nashville
State/Province
Tennessee
ZIP/Postal Code
37203-1503
Country
United States
Facility Name
Texas Oncology, P.A. - El Paso; West
City
El Paso
State/Province
Texas
ZIP/Postal Code
79902
Country
United States
Facility Name
Texas Oncology (Flower Mound) - USOR
City
Flower Mound
State/Province
Texas
ZIP/Postal Code
75028
Country
United States
Facility Name
Texas Oncology-Fort Worth Cancer Center
City
Fort Worth
State/Province
Texas
ZIP/Postal Code
76104
Country
United States
Facility Name
Baylor College of Medicine Medical Center
City
Houston
State/Province
Texas
ZIP/Postal Code
77030
Country
United States
Facility Name
Houston Methodist Cancer Center
City
Houston
State/Province
Texas
ZIP/Postal Code
77030
Country
United States
Facility Name
Joe Arrington Cancer Research & Treatment Center
City
Lubbock
State/Province
Texas
ZIP/Postal Code
79410
Country
United States
Facility Name
Texas Oncology (McAllen) - USOR
City
McAllen
State/Province
Texas
ZIP/Postal Code
78503
Country
United States
Facility Name
Texas Oncology McKinney
City
McKinney
State/Province
Texas
ZIP/Postal Code
75071
Country
United States
Facility Name
USOR - Texas Oncology - San Antonio Northeast
City
San Antonio
State/Province
Texas
ZIP/Postal Code
78217
Country
United States
Facility Name
US Oncology Research, Inc.
City
The Woodlands
State/Province
Texas
ZIP/Postal Code
77380
Country
United States
Facility Name
Texas Oncology (Tyler) - USOR
City
Tyler
State/Province
Texas
ZIP/Postal Code
75702-8363
Country
United States
Facility Name
Texas Oncology (Waco) - USOR
City
Waco
State/Province
Texas
ZIP/Postal Code
76712
Country
United States
Facility Name
Lynchburg Hem Onc Clinic Inc
City
Lynchburg
State/Province
Virginia
ZIP/Postal Code
24501
Country
United States
Facility Name
Bon Secours Mercy Health
City
Midlothian
State/Province
Virginia
ZIP/Postal Code
23114
Country
United States
Facility Name
Virginia Oncology Associates
City
Norfolk
State/Province
Virginia
ZIP/Postal Code
23502
Country
United States
Facility Name
Virginia Commonwealth University - Massey Cancer Center
City
Richmond
State/Province
Virginia
ZIP/Postal Code
23298
Country
United States
Facility Name
Oncology and Hematology Associates of Southwest Virginia, Inc.,-Blacksburg
City
Roanoke
State/Province
Virginia
ZIP/Postal Code
24014
Country
United States
Facility Name
Swedish Cancer Institute; IDS Pharmacy
City
Seattle
State/Province
Washington
ZIP/Postal Code
98104
Country
United States
Facility Name
West Virginia University Hospitals Inc
City
Morgantown
State/Province
West Virginia
ZIP/Postal Code
26056
Country
United States
Facility Name
University of Wisconsin
City
Madison
State/Province
Wisconsin
ZIP/Postal Code
53705
Country
United States
Facility Name
Froedtert and The Medical College of Wisconsin
City
Milwaukee
State/Province
Wisconsin
ZIP/Postal Code
53226
Country
United States
Facility Name
Hospital Italiano Regional del Sur
City
Bahia Blanca
ZIP/Postal Code
B8001HXM
Country
Argentina
Facility Name
Fundacion Intectus
City
Bariloche
ZIP/Postal Code
R8400CEP
Country
Argentina
Facility Name
Instituto de Investigaciones Clinicas-Mar del Plata
City
Buenos Aires
ZIP/Postal Code
B7600FZN
Country
Argentina
Facility Name
Instituto de Investigaciones Metabólicas (IDIM); Diabetes
City
Buenos Aires
ZIP/Postal Code
C1012AAQ
Country
Argentina
Facility Name
Fundación CENIT para la Investigación en Neurociencias
City
Buenos Aires
ZIP/Postal Code
C1125ABD
Country
Argentina
Facility Name
Centro Oncologico Korben
City
Caba
ZIP/Postal Code
C1426AGE
Country
Argentina
Facility Name
Fundacion Medica de Rio Negro Y Nuequen
City
Cipoletti
ZIP/Postal Code
R8324XAC
Country
Argentina
Facility Name
Consultorios Médicos Dr. Doreski
City
Ciudad Autonoma Buenos Aires
ZIP/Postal Code
C1426ABP
Country
Argentina
Facility Name
Centro Médico Privado CEMAIC
City
Cordoba
ZIP/Postal Code
X5008HHW
Country
Argentina
Facility Name
Sanatorio Allende Servicio Nefrología
City
Córdoba
ZIP/Postal Code
5000
Country
Argentina
Facility Name
Fundación Ars Medica
City
Jujuy
Country
Argentina
Facility Name
Centro Oncologico Riojano Integral (CORI)
City
La Rioja
ZIP/Postal Code
F5300COE
Country
Argentina
Facility Name
Centro de Investigaciones Medicas Mar Del Plata
City
Mar del Plata
ZIP/Postal Code
B7600DHK
Country
Argentina
Facility Name
Hospital Privado de La Comunidad
City
Mar Del Plata
ZIP/Postal Code
B7603CBM
Country
Argentina
Facility Name
Centro de Investigacion Pergamino SA
City
Pergamino
ZIP/Postal Code
B2700CPM
Country
Argentina
Facility Name
Hospital Alemán
City
Recoleta
ZIP/Postal Code
C1118AAT
Country
Argentina
Facility Name
Instituto de Especialidades de la Salud Rosario - Clínica del Tórax
City
Rosario
ZIP/Postal Code
S2000DBS
Country
Argentina
Facility Name
Instituto Medico de la Fundacion Estudios Clinicos
City
Rosario
ZIP/Postal Code
S2000DEJ
Country
Argentina
Facility Name
Sanatorio Parque de Rosario
City
Rosario
ZIP/Postal Code
S2000DSV
Country
Argentina
Facility Name
Instituto de Oncologia de Rosario
City
Rosario
ZIP/Postal Code
S2013KZE
Country
Argentina
Facility Name
Centro de Investigacion en Oncologie - IMAC
City
Salta
ZIP/Postal Code
4400
Country
Argentina
Facility Name
Centro Polivalente de Asistencia e Investigacion Clinica - CER San Juan
City
San Juan
ZIP/Postal Code
J5402DIL
Country
Argentina
Facility Name
Centro Médico Privado de Reumatología
City
San Miguel de Tucuman
ZIP/Postal Code
T4000AXL
Country
Argentina
Facility Name
Centro Medico San Roque
City
San Miguel de Tucuman
ZIP/Postal Code
T4000IAK
Country
Argentina
Facility Name
Organizacion Medica de Investigacion
City
San Nicolás
ZIP/Postal Code
C1015ABO
Country
Argentina
Facility Name
Centro de Investigación Clínica ? Clínica Viedma
City
Viedma
ZIP/Postal Code
R8500ACE
Country
Argentina
Facility Name
Border Medical Oncology Research Unit
City
Albury
State/Province
New South Wales
ZIP/Postal Code
2640
Country
Australia
Facility Name
Bankstown-Lidcombe Hospital
City
Bankstown
State/Province
New South Wales
ZIP/Postal Code
2200
Country
Australia
Facility Name
Campbelltown Hospital
City
Campbelltown
State/Province
New South Wales
ZIP/Postal Code
2560
Country
Australia
Facility Name
Kinghorn Cancer Centre; Pharmacy Department
City
Darlinghurst
State/Province
New South Wales
ZIP/Postal Code
2010
Country
Australia
Facility Name
Liverpool Hospital; Cancer Therapy Centre
City
Liverpool
State/Province
New South Wales
ZIP/Postal Code
2170
Country
Australia
Facility Name
Mater Hospital; Patricia Ritchie Centre for Cancer Care and Research
City
North Sydney
State/Province
New South Wales
ZIP/Postal Code
2060
Country
Australia
Facility Name
Westmead Hospital; Pharmacy Distribution Centre
City
Northmead
State/Province
New South Wales
ZIP/Postal Code
2152
Country
Australia
Facility Name
North Coast Cancer Institute - Port Macquarie
City
Port Macquarie
State/Province
New South Wales
ZIP/Postal Code
2444
Country
Australia
Facility Name
Nepean Cancer Care Centre
City
Sydney
State/Province
New South Wales
ZIP/Postal Code
2747
Country
Australia
Facility Name
Wesley Medical Centre; Clinic For Haematology and Oncology
City
Auchenflower
State/Province
Queensland
ZIP/Postal Code
4066
Country
Australia
Facility Name
Mater Cancer Care Centre
City
Brisbane
State/Province
Queensland
ZIP/Postal Code
4101
Country
Australia
Facility Name
Cairns Hospital; Renal Services
City
Crains
State/Province
Queensland
ZIP/Postal Code
4870
Country
Australia
Facility Name
Townsville Hospital
City
Townsville
State/Province
Queensland
ZIP/Postal Code
4810
Country
Australia
Facility Name
Princess Alexandra Hospital
City
Woolloongabba
State/Province
Queensland
ZIP/Postal Code
4102
Country
Australia
Facility Name
Royal Adelaide Hospital
City
Adelaide
State/Province
South Australia
ZIP/Postal Code
5000
Country
Australia
Facility Name
St Andrews Medical Centre
City
Adelaide
State/Province
South Australia
ZIP/Postal Code
5000
Country
Australia
Facility Name
Flinders Medical Centre
City
Bedford Park
State/Province
South Australia
ZIP/Postal Code
5042
Country
Australia
Facility Name
Adelaide Cancer Centre
City
Kurralta Park
State/Province
South Australia
ZIP/Postal Code
5037
Country
Australia
Facility Name
ICON Cancer Care Hobart
City
Hobart
State/Province
Tasmania
ZIP/Postal Code
7000
Country
Australia
Facility Name
Bendigo Hospital
City
Bendigo
State/Province
Victoria
ZIP/Postal Code
3550
Country
Australia
Facility Name
Box Hill Hospital
City
Box Hill
State/Province
Victoria
ZIP/Postal Code
3128
Country
Australia
Facility Name
Victorian Breast and Oncology Care
City
East Melbourne
State/Province
Victoria
ZIP/Postal Code
3002
Country
Australia
Facility Name
Northern Hospital
City
Epping
State/Province
Victoria
ZIP/Postal Code
3076
Country
Australia
Facility Name
Frankston Hospital; Oncology/Haematology
City
Frankston
State/Province
Victoria
ZIP/Postal Code
3199
Country
Australia
Facility Name
Maroondah Hospital; Breast Clinic
City
Ringwood East
State/Province
Victoria
ZIP/Postal Code
3135
Country
Australia
Facility Name
Goulburn Valley Health
City
Shepparton
State/Province
Victoria
ZIP/Postal Code
3630
Country
Australia
Facility Name
Sunshine Hospital
City
St Albans
State/Province
Victoria
ZIP/Postal Code
3021
Country
Australia
Facility Name
South West Oncology
City
Warrnambool
State/Province
Victoria
ZIP/Postal Code
3280
Country
Australia
Facility Name
Ballarat Oncology & Haematology
City
Wendouree
State/Province
Victoria
ZIP/Postal Code
3355
Country
Australia
Facility Name
Sir Charles Gairdner Hospital
City
Nedlands
State/Province
Western Australia
ZIP/Postal Code
6009
Country
Australia
Facility Name
LKH-Universitätsklinikum Klinikum Graz
City
Graz
ZIP/Postal Code
8036
Country
Austria
Facility Name
Medizinische Universitat Innsbruck; Department of Internal Medicine, Pneumology Centre
City
Innsbruck
ZIP/Postal Code
6020
Country
Austria
Facility Name
Ordensklinikum Linz GmbH
City
Linz
ZIP/Postal Code
4010
Country
Austria
Facility Name
LKH Rankweil, Interne E
City
Rankweil
ZIP/Postal Code
6830
Country
Austria
Facility Name
Universitätsklinikum Salzburg
City
Salzburg
ZIP/Postal Code
5020
Country
Austria
Facility Name
Universitätsklinikum St. Pölten; Klinische Abteilung für Innere Medizin 1
City
St. Pölten
ZIP/Postal Code
3100
Country
Austria
Facility Name
A.ö. Krankenhaus der Barmherzigen Brüder
City
St. Veit
ZIP/Postal Code
9300
Country
Austria
Facility Name
Oö. Gesundheits- und Spitals-AG/LKH Steyr
City
Steyr
ZIP/Postal Code
4400
Country
Austria
Facility Name
Klinikum Wels-Grieskirchen GmbH
City
Wels
ZIP/Postal Code
4600
Country
Austria
Facility Name
Medizinische Universitat Wien Medical University of Vienna
City
Wien
ZIP/Postal Code
1090
Country
Austria
Facility Name
Institute Jules Bordet; Med Onc & Translational Rsch
City
Belgium
ZIP/Postal Code
1000
Country
Belgium
Facility Name
Cliniques Universitaires Saint-Luc
City
Bruxelles
ZIP/Postal Code
1200
Country
Belgium
Facility Name
Grand Hopital de Charleroi asbl
City
Charleroi
ZIP/Postal Code
6000
Country
Belgium
Facility Name
UZ Antwerpen
City
Edegem
ZIP/Postal Code
2650
Country
Belgium
Facility Name
UZ Gent
City
Gent
ZIP/Postal Code
9000
Country
Belgium
Facility Name
UZ Leuven
City
Leuven
ZIP/Postal Code
3000
Country
Belgium
Facility Name
CH de l'Ardenne (Libramont)
City
Libramont-Chevigny
ZIP/Postal Code
6800
Country
Belgium
Facility Name
Chu Sart Tilman; Medical Oncology
City
Liege
ZIP/Postal Code
4000
Country
Belgium
Facility Name
Centre Hospitalier Chrétien MontLégia
City
Liège
ZIP/Postal Code
4000
Country
Belgium
Facility Name
CHR de la Citadelle, Pharmacie
City
Liège
ZIP/Postal Code
4000
Country
Belgium
Facility Name
Clinique Sainte-Elisabeth; Oncologie
City
Namur
ZIP/Postal Code
5000
Country
Belgium
Facility Name
Cliniques Universitaires UCL de Mont-Godinne
City
Namur
ZIP/Postal Code
5530
Country
Belgium
Facility Name
GZA Ziekenhuizen Antwerpen campus Sint-Augustinus
City
Wilrijk
ZIP/Postal Code
2610
Country
Belgium
Facility Name
Clinical Center Banja Luka
City
Banja Luka
ZIP/Postal Code
78000
Country
Bosnia and Herzegovina
Facility Name
Clinical Hospital Mostar
City
Mostar
ZIP/Postal Code
88000
Country
Bosnia and Herzegovina
Facility Name
Clinical Center University of Sarajevo; Oncology Institute
City
Sarajevo
ZIP/Postal Code
71000
Country
Bosnia and Herzegovina
Facility Name
University Clinical Center Tuzla
City
Tuzla
ZIP/Postal Code
75000
Country
Bosnia and Herzegovina
Facility Name
Nucleo de Oncologia da Bahia - NOB
City
Salvador, Bahia
State/Province
BA
ZIP/Postal Code
40170-380
Country
Brazil
Facility Name
Centro de Oncologia da Bahia; Centro Médico Iguatemi
City
Salvador/BA
State/Province
BA
ZIP/Postal Code
41820-021
Country
Brazil
Facility Name
Centro Odonito Medico Linus Pauling - Clinica de O
City
Salvador
State/Province
BA
ZIP/Postal Code
41830-907
Country
Brazil
Facility Name
Terapia de Inovação Clínica Assistência Multidiciplinar Em Oncologia Ética
City
Salvador
State/Province
BA
ZIP/Postal Code
41950-640
Country
Brazil
Facility Name
Centro de Pesquisas Clinicas em Oncologia - CPCO
City
Cachoeiro de Itapemirim
State/Province
ES
ZIP/Postal Code
29308-014
Country
Brazil
Facility Name
Hospital Araujo Jorge
City
Goiania
State/Province
GO
ZIP/Postal Code
74605-070
Country
Brazil
Facility Name
Cenantron - Centro Avancado de Tratamento Oncologico
City
Belo Horizonte
State/Province
MG
ZIP/Postal Code
30130-090
Country
Brazil
Facility Name
Oncocentro Belo Horizonte
City
Belo Horizonte
State/Province
MG
ZIP/Postal Code
30360-680
Country
Brazil
Facility Name
Hospital de Clinicas de Porto Alegre HCPA PPDS
City
Porto Alegre
State/Province
PA
ZIP/Postal Code
90035-903
Country
Brazil
Facility Name
Hospital do Cancer de Pernambuco - HCP
City
Recife
State/Province
PE
ZIP/Postal Code
50040-000
Country
Brazil
Facility Name
Instituto Nacional de Cancer - INCa; Oncologia
City
Rio de Janeiro
State/Province
RJ
ZIP/Postal Code
20560-120
Country
Brazil
Facility Name
Universidade de Caxias do Sul - Rio Grande do Sul
City
Caxias do Sul
State/Province
RS
ZIP/Postal Code
95070-560
Country
Brazil
Facility Name
Hospital de Caridade de Ijui; Oncologia
City
Ijui
State/Province
RS
ZIP/Postal Code
98700-000
Country
Brazil
Facility Name
Hospital Bruno Born; Oncologia
City
Lajeado
State/Province
RS
ZIP/Postal Code
95900-000
Country
Brazil
Facility Name
Hospital São Vicente de Paulo X
City
Passo Fundo
State/Province
RS
ZIP/Postal Code
99010-080
Country
Brazil
Facility Name
Hospital Moinhos de Vento
City
Porto Alegre
State/Province
RS
ZIP/Postal Code
90035-000
Country
Brazil
Facility Name
Irmandade Da Santa Casa de Misericordia de Porto Alegre; Hospital Dom Vicente Scherer
City
Porto Alegre
State/Province
RS
ZIP/Postal Code
90035-074
Country
Brazil
Facility Name
Hospital Mae de Deus
City
Porto Alegre
State/Province
RS
ZIP/Postal Code
90110-000
Country
Brazil
Facility Name
Hospital Sao Lucas - PUCRS
City
Porto Alegre
State/Province
RS
ZIP/Postal Code
90610-000
Country
Brazil
Facility Name
Hospital Nossa Senhora da Conceição; Ambulatório de Pneumologia
City
Porto Alegre
State/Province
RS
ZIP/Postal Code
91350-200
Country
Brazil
Facility Name
Clinica de Neoplasias Litoral
City
Itajai
State/Province
SC
ZIP/Postal Code
88301-220
Country
Brazil
Facility Name
*X*Fundação Pio XII Hospital de Câncer de Barretos
City
Barretos
State/Province
SP
ZIP/Postal Code
14784-400
Country
Brazil
Facility Name
Hospital Amaral Carvalho
City
Jau
State/Province
SP
ZIP/Postal Code
17210-120
Country
Brazil
Facility Name
Instituto de Oncologia Clínica de Piracicaba
City
Piracicaba
State/Province
SP
ZIP/Postal Code
13419-160
Country
Brazil
Facility Name
Faculdade de Medicina do ABC - FMABC
City
Santo Andre
State/Province
SP
ZIP/Postal Code
09060-650
Country
Brazil
Facility Name
Fundação Faculdade Regional de Medicina de São José do Rio Preto
City
Sao Jose Do Rio Preto
State/Province
SP
ZIP/Postal Code
15090-000
Country
Brazil
Facility Name
Instituto do Cancer do Estado de Sao Paulo - ICESP
City
Sao Paulo
State/Province
SP
ZIP/Postal Code
01246-000
Country
Brazil
Facility Name
Onco Star Sp Oncologia Ltda
City
Sao Paulo
State/Province
SP
ZIP/Postal Code
04543-000
Country
Brazil
Facility Name
Instituto de Oncologia de Sorocaba - CEPOS
City
Sorocaba
State/Province
SP
ZIP/Postal Code
18030-005
Country
Brazil
Facility Name
Instituto Brasileiro De Controle Do Câncer - IBCC; Laboratório De Patologia
City
São Paulo
State/Province
SP
ZIP/Postal Code
03102-002
Country
Brazil
Facility Name
Clinica de Pesquisas e Centro de Estudos Oncologia Ginecologica e Mamaria Ltda
City
São Paulo
State/Province
SP
ZIP/Postal Code
0317-0001
Country
Brazil
Facility Name
Complex Oncology Center Burgas; Medical Oncology Department
City
Burgas
ZIP/Postal Code
8000
Country
Bulgaria
Facility Name
Multiprofile Hospital for Active Treatment Uni Hospital; Department of medicinal oncology
City
Panagyurishte
ZIP/Postal Code
4500
Country
Bulgaria
Facility Name
Tom Baker Cancer Centre-Calgary
City
Calgary
State/Province
Alberta
ZIP/Postal Code
T2N 4N2
Country
Canada
Facility Name
Cross Cancer Institute
City
Edmonton
State/Province
Alberta
ZIP/Postal Code
T6G 1Z2
Country
Canada
Facility Name
British Columbia Cancer Agency
City
Vancouver
State/Province
British Columbia
ZIP/Postal Code
V5Z 4R2
Country
Canada
Facility Name
The Moncton Hospital
City
Moncton
State/Province
New Brunswick
ZIP/Postal Code
E1C 6Z8
Country
Canada
Facility Name
Sault Area Hospital
City
Sault Ste. Marie
State/Province
Ontario
ZIP/Postal Code
P6B 0A8
Country
Canada
Facility Name
Centre Integre Universitaire de Sante et de Services Sociaux du Saguenay Lac Saint Jean
City
Chicoutimi
State/Province
Quebec
ZIP/Postal Code
G7H 5H6
Country
Canada
Facility Name
Hopital Charles Le Moyne
City
Greenfield Park
State/Province
Quebec
ZIP/Postal Code
J4V 2H1
Country
Canada
Facility Name
CIUSSS de l'Est-de-l'Ile-de-Montréal - Hôpital Maisonneuve-Rosemont
City
Montreal
State/Province
Quebec
ZIP/Postal Code
H1T 2M4
Country
Canada
Facility Name
CHUM
City
Montreal
State/Province
Quebec
ZIP/Postal Code
H2X 3E4
Country
Canada
Facility Name
Sir Mortimer B Davis Jewish General Hospital
City
Montreal
State/Province
Quebec
ZIP/Postal Code
H3T 1E2
Country
Canada
Facility Name
McGill University Health Center
City
Montreal
State/Province
Quebec
ZIP/Postal Code
H4A 3J1
Country
Canada
Facility Name
St-Jérome Medical Research, Inc.
City
Saint-Jerome
State/Province
Quebec
ZIP/Postal Code
H7Z 5T3
Country
Canada
Facility Name
Centre Hospitalier Universitaire de Sherbrooke
City
Sherbrooke
State/Province
Quebec
ZIP/Postal Code
J1H 5N4
Country
Canada
Facility Name
Allan Blair Cancer Centre
City
Regina
State/Province
Saskatchewan
ZIP/Postal Code
S4T 7T1
Country
Canada
Facility Name
CHU de Quebec-Universite Laval
City
Quebec
ZIP/Postal Code
G1S 4L8
Country
Canada
Facility Name
IC La Serena Research SpA
City
La Serena
ZIP/Postal Code
1700000
Country
Chile
Facility Name
BIOCINETIC SpA
City
Peñalolen
ZIP/Postal Code
7910000
Country
Chile
Facility Name
Centro de Estudios Clínicos SAGA SpA
City
Providencia
ZIP/Postal Code
7500000
Country
Chile
Facility Name
Fundacion Arturo Lopez Perez; Quimioterapia
City
Providencia
ZIP/Postal Code
7500921
Country
Chile
Facility Name
Oncovida - Santiago
City
Providencia
ZIP/Postal Code
7510035
Country
Chile
Facility Name
Patagonia Research
City
Puerto Montt
ZIP/Postal Code
5480000
Country
Chile
Facility Name
Servicios Médicos URUMED SpA
City
Rancagua
Country
Chile
Facility Name
Meditek Ltda
City
Santiago
ZIP/Postal Code
8320000
Country
Chile
Facility Name
Icegclinic
City
Santiago
Country
Chile
Facility Name
Medwal
City
Santiago
Country
Chile
Facility Name
Clinica Universidad Catolica del Maule
City
Talca
ZIP/Postal Code
3460000
Country
Chile
Facility Name
Sociedad de Investigaciones Medicas Ltda (SIM)
City
Temuco
ZIP/Postal Code
4800827
Country
Chile
Facility Name
ONCOCENTRO APYS; Oncología
City
Vina Del Mar
ZIP/Postal Code
2520598
Country
Chile
Facility Name
Centro de Investigaciones Clinicas Viña del Mar
City
Viña del Mar
ZIP/Postal Code
2540333
Country
Chile
Facility Name
Peking University People's Hospital
City
Beijing
ZIP/Postal Code
100044
Country
China
Facility Name
The First Hospital of Jilin University
City
Changchun City
ZIP/Postal Code
130021
Country
China
Facility Name
Jilin Cancer Hospital
City
Changchun
ZIP/Postal Code
132013
Country
China
Facility Name
Xiangya Hospital Central South University
City
Changsha City
ZIP/Postal Code
410008
Country
China
Facility Name
Hunan Cancer Hospital
City
Changsha CITY
ZIP/Postal Code
410013
Country
China
Facility Name
West China Hospital, Sichuan University
City
Chengdu
ZIP/Postal Code
610041
Country
China
Facility Name
The First Affiliated Hospital, Chongqing Medical University
City
Chongqing
ZIP/Postal Code
400016
Country
China
Facility Name
The Second Affiliated Hospital of Dalian Medical University
City
Dalian
ZIP/Postal Code
116027
Country
China
Facility Name
Fujian Provincial Cancer Hospital
City
Fuzhou City
ZIP/Postal Code
350014
Country
China
Facility Name
Guangdong Provincial Maternity and Child Care Cent
City
Guangzhou
ZIP/Postal Code
510010
Country
China
Facility Name
Sun yat-sen University Cancer Center; Internal Medicine of Oncology
City
Guangzhou
ZIP/Postal Code
510060
Country
China
Facility Name
The Second Affiliated Hospital of Zhejiang University School of Medicine
City
Hangzhou City
ZIP/Postal Code
310009
Country
China
Facility Name
Sir Run Run Shaw Hospital Zhejiang University
City
Hangzhou City
ZIP/Postal Code
310016
Country
China
Facility Name
The First Affiliated Hospital of College of Medicine, Zhejiang University
City
Hangzhou
ZIP/Postal Code
310003
Country
China
Facility Name
Harbin Medical University Cancer Hospital
City
Harbin
ZIP/Postal Code
150081
Country
China
Facility Name
Anhui Province Cancer Hospital
City
Hefei City
ZIP/Postal Code
230031
Country
China
Facility Name
Jinan Central Hospital
City
Jinan City
ZIP/Postal Code
250013
Country
China
Facility Name
Yunnan Cancer Hospital
City
Kunming
ZIP/Postal Code
650118
Country
China
Facility Name
Linyishi Cancer Hospital
City
Linyi City
ZIP/Postal Code
276034
Country
China
Facility Name
The Third Hospital of Nanchang
City
Nanchang City
ZIP/Postal Code
330009
Country
China
Facility Name
Jiangxi Cancer Hospital
City
Nanchang City
ZIP/Postal Code
330029
Country
China
Facility Name
Guangxi Cancer Hospital of Guangxi Medical University
City
Nanning
ZIP/Postal Code
530021
Country
China
Facility Name
The Second People's Hospital of Neijiang
City
Neijiang
ZIP/Postal Code
641000
Country
China
Facility Name
Fudan University Shanghai Cancer Center
City
Shanghai City
ZIP/Postal Code
200120
Country
China
Facility Name
Shengjing Hospital of China Medical University
City
ShenYang
ZIP/Postal Code
110004
Country
China
Facility Name
The Fourth Hospital of Hebei Medical University
City
Shijiazhuang
ZIP/Postal Code
050000
Country
China
Facility Name
The First Affiliated Hospital of Soochow University
City
Suzhou City
ZIP/Postal Code
215006
Country
China
Facility Name
Tianjin Medical University Cancer Institute & Hospital
City
Tianjing
ZIP/Postal Code
300060
Country
China
Facility Name
Wenzhou Medical College - The First Affiliated Hospital GCP
City
Wenzhou City
ZIP/Postal Code
325000
Country
China
Facility Name
Union Hospital Tongji Medical College Huazhong University of Science and Technology
City
Wuhan City
ZIP/Postal Code
430023
Country
China
Facility Name
Tongji Hospital Tongji Medical College Huazhong University of Science and Technology
City
Wuhan City
ZIP/Postal Code
430030
Country
China
Facility Name
Hubei Cancer Hospital
City
Wuhan
ZIP/Postal Code
430079
Country
China
Facility Name
Air Force Military Medical University Xijing Hospital
City
Xi'an City
ZIP/Postal Code
710032
Country
China
Facility Name
First Affiliated Hospital of Medical College of Xi'an Jiaotong University
City
Xi'an
ZIP/Postal Code
710061
Country
China
Facility Name
The First Affiliated Hospital of Xiamen University
City
Xiamen
ZIP/Postal Code
361003
Country
China
Facility Name
The Affiliated Hospital of Xuzhou Medical University
City
Xuzhou
Country
China
Facility Name
Zhejiang Cancer Hospital
City
Zhejiang
ZIP/Postal Code
310022
Country
China
Facility Name
Henan Cancer Hospital
City
Zhengzhou
ZIP/Postal Code
450008
Country
China
Facility Name
Hemato Oncólogos S.A
City
Cali
ZIP/Postal Code
760042
Country
Colombia
Facility Name
FOSCAL
City
Floridablanca
Country
Colombia
Facility Name
Oncomedica S.A.
City
Monteria
ZIP/Postal Code
230002
Country
Colombia
Facility Name
Oncólogos Del Occidente SA
City
Pereira
ZIP/Postal Code
660001
Country
Colombia
Facility Name
Sociedad de Oncología y hematología del Cesar Ltda
City
Valledupar
ZIP/Postal Code
200001
Country
Colombia
Facility Name
Consultorio Oncologico-Hospital Metropolitano Linc
City
Moravia
ZIP/Postal Code
11401
Country
Costa Rica
Facility Name
Instituto de Investigación en Ciencias Médicas S.A.
City
San Jose
Country
Costa Rica
Facility Name
Centro de Cáncer y Hematología
City
San José
ZIP/Postal Code
10103
Country
Costa Rica
Facility Name
Consultorio Oncologico-Hospital Metropolitano San
City
San José
ZIP/Postal Code
10103
Country
Costa Rica
Facility Name
Oncotech S.A.
City
San José
ZIP/Postal Code
10103
Country
Costa Rica
Facility Name
Clinical Hospital Centre Osijek
City
Osijek
ZIP/Postal Code
31000
Country
Croatia
Facility Name
General Hospital Pula
City
Pula
ZIP/Postal Code
52100
Country
Croatia
Facility Name
University Hospital Centre Split
City
Split
ZIP/Postal Code
21000
Country
Croatia
Facility Name
General Hospital Varazdin
City
Varazdin
ZIP/Postal Code
42000
Country
Croatia
Facility Name
Clinical Hospital Sestre Milosrdnice
City
Zagreb
ZIP/Postal Code
10000
Country
Croatia
Facility Name
Klinicki bolnicki centar Zagreb
City
Zagreb
ZIP/Postal Code
10000
Country
Croatia
Facility Name
Nemocnice AGEL Novy Jicin a.s.; Oddeleni radioterapie a onkologie
City
Novy Jicin
ZIP/Postal Code
741 01
Country
Czechia
Facility Name
Fakultni nemocnice Olomouc
City
Olomouc
ZIP/Postal Code
779 00
Country
Czechia
Facility Name
Vseobecna fakultni nemocnice v Praze
City
Praha 2
ZIP/Postal Code
128 08
Country
Czechia
Facility Name
Fakultni nemocnice v Motole
City
Praha 5
ZIP/Postal Code
150 06
Country
Czechia
Facility Name
Fakultni nemocnice Kralovske Vinohrady
City
Praha
ZIP/Postal Code
100 34
Country
Czechia
Facility Name
Fakultni Thomayerova Nemocnice; Onkologicke Oddeleni
City
Praha
ZIP/Postal Code
140 59
Country
Czechia
Facility Name
ALEXANDRIA UNI; Clinical Research Center
City
Alexandria
Country
Egypt
Facility Name
Medical Technology Center for Research and Services
City
Alexandria
Country
Egypt
Facility Name
Ain Shams University Hospital
City
Cairo
ZIP/Postal Code
11566
Country
Egypt
Facility Name
Kasr Al Ainy School of Medicine-Cairo University
City
Cairo
ZIP/Postal Code
12613
Country
Egypt
Facility Name
Sohag Oncology Center
City
Cairo
Country
Egypt
Facility Name
Mansoura University Hospital
City
Dakahlia
ZIP/Postal Code
324
Country
Egypt
Facility Name
Dar ElSalam Cancer City
City
Old Cairo
ZIP/Postal Code
11632
Country
Egypt
Facility Name
Helsingin yliopistollinen keskussairaala
City
Helsinki
ZIP/Postal Code
00290
Country
Finland
Facility Name
Tampereen yliopistollinen sairaala
City
Tampere
ZIP/Postal Code
33520
Country
Finland
Facility Name
Turun Yliopistollinen Keskussairaala
City
Turku
ZIP/Postal Code
20540
Country
Finland
Facility Name
Sas Clinique De L Europe - Amiens
City
Amiens
ZIP/Postal Code
80090
Country
France
Facility Name
Hopital d'Argenteuil
City
Argenteuil
ZIP/Postal Code
95100
Country
France
Facility Name
CHRU de Brest - Hopital Morvan
City
Brest
ZIP/Postal Code
29609
Country
France
Facility Name
Centre Francois Baclesse
City
Caen
ZIP/Postal Code
14076
Country
France
Facility Name
Institut Daniel Hollard
City
Grenoble
ZIP/Postal Code
38000
Country
France
Facility Name
Centre Hospitalier Departemental de Vendee
City
La Roche Sur Yon
ZIP/Postal Code
85925
Country
France
Facility Name
Centre Jean Bernard Clinique Victor Hugo
City
Le Mans
ZIP/Postal Code
72015
Country
France
Facility Name
Centre Oscar Lambret
City
Lille
ZIP/Postal Code
59020
Country
France
Facility Name
CHU Dupuytren
City
Limoges
ZIP/Postal Code
87042
Country
France
Facility Name
Hôpital Privé Clairval
City
Marseille
ZIP/Postal Code
13273
Country
France
Facility Name
Clinique Clémentville
City
Montpellier
ZIP/Postal Code
34070
Country
France
Facility Name
Clinique Catherine de Sienne
City
Nantes
ZIP/Postal Code
44202
Country
France
Facility Name
Institut Curie
City
Paris
ZIP/Postal Code
75005
Country
France
Facility Name
Hopital Universitaire Pitie Salpetriere
City
Paris
ZIP/Postal Code
75013
Country
France
Facility Name
Hopital Tenon
City
Paris
ZIP/Postal Code
75020
Country
France
Facility Name
Hopital Saint Louis
City
Paris
ZIP/Postal Code
75475
Country
France
Facility Name
Hôpital Européen Georges Pompidou
City
Paris
ZIP/Postal Code
75908
Country
France
Facility Name
Hopital privé des Côtes Armor
City
Plérin
ZIP/Postal Code
22190
Country
France
Facility Name
EDOG - Centre Eugene Marquis Centre Regional de Lutte Contre Le Cancer - PPDS
City
Rennes Cedex
ZIP/Postal Code
35042
Country
France
Facility Name
Centre Henri Becquerel
City
Rouen
ZIP/Postal Code
76038
Country
France
Facility Name
Curie Saint Cloud
City
St Cloud
ZIP/Postal Code
92210
Country
France
Facility Name
Institut de Cancérologie Strasbourg Europe
City
Strasbourg
ZIP/Postal Code
67033
Country
France
Facility Name
Institut Gustave Roussy
City
Villejuif
ZIP/Postal Code
94805
Country
France
Facility Name
High Technology Hospital MedCenter Ltd
City
Batumi
ZIP/Postal Code
6000
Country
Georgia
Facility Name
Acad. F. Todua Medical Center
City
Tbilisi
ZIP/Postal Code
0112
Country
Georgia
Facility Name
Ltd Israel-Georgia Medical Research Clinic Helsicore
City
Tbilisi
ZIP/Postal Code
0112
Country
Georgia
Facility Name
LTD Health House
City
Tbilisi
ZIP/Postal Code
0144
Country
Georgia
Facility Name
Institute of Clinical Oncology LTD
City
Tbilisi
ZIP/Postal Code
0159
Country
Georgia
Facility Name
Tbilisi Oncology Dispensary
City
Tbilisi
ZIP/Postal Code
0159
Country
Georgia
Facility Name
LTD TIM, Tbilisi Institute of Medicine
City
Tbilisi
ZIP/Postal Code
0160
Country
Georgia
Facility Name
Multiprofile Clinic Consilium Medulla
City
Tbilisi
ZIP/Postal Code
0186
Country
Georgia
Facility Name
S Khechinashvili University Clinic Ltd
City
Tbilisi
ZIP/Postal Code
179
Country
Georgia
Facility Name
Hämatologisch/onkologische Gemeinschaftspraxis; Dres. Brudler/Heinrich/Bangerter
City
Augsburg
ZIP/Postal Code
86150
Country
Germany
Facility Name
Ambulantes Tumorzentrum Spandau
City
Berlin
ZIP/Postal Code
13581
Country
Germany
Facility Name
Lübecker Onkologische Schwerpunktpraxis
City
Bonn
ZIP/Postal Code
53111
Country
Germany
Facility Name
Marienhospital Bottrop
City
Bottrop
ZIP/Postal Code
46236
Country
Germany
Facility Name
Klinikum Chemnitz gGmbH
City
Chemnitz
ZIP/Postal Code
09116
Country
Germany
Facility Name
Universitaetsklinikum Carl Gustav Carus an der TU Dresden
City
Dresden
ZIP/Postal Code
01307
Country
Germany
Facility Name
UNIVERSITATSKLINIKUM ERLANGEN; Department of Gynecology and Obstetrics
City
Erlangen
ZIP/Postal Code
91054
Country
Germany
Facility Name
Kliniken Essen Mitte Evang. Huyssens Stiftung/Knappschaft GmbH
City
Essen
ZIP/Postal Code
45136
Country
Germany
Facility Name
Universitätsklinikum Essen
City
Essen
ZIP/Postal Code
45147
Country
Germany
Facility Name
Franziskus-Hospital Harderberg
City
Georgsmarienhutte
ZIP/Postal Code
49124
Country
Germany
Facility Name
SRH Wald-Klinikum Gera; Brustzentrum Ostthüringen
City
Gera
ZIP/Postal Code
07548
Country
Germany
Facility Name
Mammazentrum Hamburg am Krankenhaus Jerusalem
City
Hamburg
ZIP/Postal Code
20357
Country
Germany
Facility Name
Gynäkologisch Onkologische Praxis Hannover
City
Hannover
ZIP/Postal Code
30177
Country
Germany
Facility Name
Vincentius-Diakonissen-Kliniken gAG
City
Karlsruhe
ZIP/Postal Code
76137
Country
Germany
Facility Name
Facharztpraxis für Gynäkologie und Geburtshilfe PD Dr. med. Christian Kurbacher
City
Lübeck
ZIP/Postal Code
23562
Country
Germany
Facility Name
Universitätsmedizin der Johannes Gutenberg-Universität Mainz
City
Mainz
ZIP/Postal Code
55101
Country
Germany
Facility Name
Klinikum Mannheim GmbH Universitätsklinikum
City
Mannheim
ZIP/Postal Code
68167
Country
Germany
Facility Name
Praxis fuer gynaekologische onkologie Prof. Dr. me
City
Mönchengladbach
ZIP/Postal Code
41061
Country
Germany
Facility Name
Universitatsklinikum Munster
City
Münster
ZIP/Postal Code
48149
Country
Germany
Facility Name
Hämatologie und Onkologie Ravensburg / Wangen
City
Ravensburg
ZIP/Postal Code
88212
Country
Germany
Facility Name
CaritasKlinikum Saarbruecken St Theresia
City
Saarbrücken
ZIP/Postal Code
66113
Country
Germany
Facility Name
Leopoldina Krankenhaus Schweinfurt
City
Schweinfurt
ZIP/Postal Code
97422
Country
Germany
Facility Name
Praxis fur Haematologie und Internistische Onkologie
City
Velbert
ZIP/Postal Code
42551
Country
Germany
Facility Name
Henry Dunant Hospital
City
Athens
ZIP/Postal Code
115 26
Country
Greece
Facility Name
University of Athens Medical School - Regional General Hospital Alexandra
City
Athens
ZIP/Postal Code
115 28
Country
Greece
Facility Name
Sotiria Chest Hospital of Athens
City
Athens
ZIP/Postal Code
11527
Country
Greece
Facility Name
General Oncology Hospital Kifissias "Oi Agioi Anargyroi"
City
Athens
ZIP/Postal Code
145 64
Country
Greece
Facility Name
Aretaieio Hospital of Athens
City
Athina
ZIP/Postal Code
115 28
Country
Greece
Facility Name
Attikon University General Hospital
City
Chaidari
ZIP/Postal Code
124 62
Country
Greece
Facility Name
Metropolitan General Hospital
City
Cholargos
ZIP/Postal Code
155 62
Country
Greece
Facility Name
Metropolitan Hospital First Oncology Clinic
City
Faliro
ZIP/Postal Code
185 47
Country
Greece
Facility Name
Metropolitan Hospital Fourth Oncology Clinic
City
Faliro
ZIP/Postal Code
185 47
Country
Greece
Facility Name
University General Hospital of Heraklion
City
Heraklio
ZIP/Postal Code
711 10
Country
Greece
Facility Name
University General Hospital of Ioannina
City
Ioannina
ZIP/Postal Code
455 00
Country
Greece
Facility Name
University General Hospital of Larissa
City
Larissa
ZIP/Postal Code
412 21
Country
Greece
Facility Name
IASO Obstetrics Gynecology Clinic
City
Marousi
ZIP/Postal Code
151 23
Country
Greece
Facility Name
Medical Center of Athens
City
Marousi
ZIP/Postal Code
151 25
Country
Greece
Facility Name
Agios Loucas Clinic SA
City
Panorama
ZIP/Postal Code
552 36
Country
Greece
Facility Name
Olympion Clinic
City
Patras
ZIP/Postal Code
264 43
Country
Greece
Facility Name
University General Hospital of Patras
City
Patras
ZIP/Postal Code
265 00
Country
Greece
Facility Name
Bioclinic Thessaloniki
City
Thessaloniki
ZIP/Postal Code
546 22
Country
Greece
Facility Name
Interbalkan Medical Center of Thessaloniki
City
Thessaloniki
ZIP/Postal Code
546 39
Country
Greece
Facility Name
Euromedica PPDS
City
Thessaloniki
ZIP/Postal Code
546 45
Country
Greece
Facility Name
Papageorgiou General Hospital of Thessaloniki
City
Thessaloniki
ZIP/Postal Code
564 29
Country
Greece
Facility Name
Celan S.A.
City
Ciudad de Guatemala
ZIP/Postal Code
01010
Country
Guatemala
Facility Name
INTEGRA Cancer Institute
City
Ciudad de Guatemala
ZIP/Postal Code
01010
Country
Guatemala
Facility Name
Grupo Medico Angeles
City
Ciudad de Guatemala
ZIP/Postal Code
01015
Country
Guatemala
Facility Name
Oncomedica
City
Guatemala
ZIP/Postal Code
01010
Country
Guatemala
Facility Name
Clínica Médica Especializada en Hematología
City
Guatemala
ZIP/Postal Code
01234
Country
Guatemala
Facility Name
Centro Medico Integral de Cancerologia CEMIC
City
Salcajá
ZIP/Postal Code
09002
Country
Guatemala
Facility Name
Pamela Youde Nethersole Eastern Hospital; Department Of Pediatrics
City
Chai Wan
Country
Hong Kong
Facility Name
Queen Mary Hospital
City
Hong Kong
Country
Hong Kong
Facility Name
Tuen Mun Hospital
City
Hong Kong
Country
Hong Kong
Facility Name
Semmelweis Egyetem
City
Budapest
ZIP/Postal Code
1088
Country
Hungary
Facility Name
Tolna Megyei Balassa János Kórház
City
Budapest
ZIP/Postal Code
1136
Country
Hungary
Facility Name
Budapesti Uzsoki Utcai Kórház
City
Budapest
ZIP/Postal Code
1145
Country
Hungary
Facility Name
Debreceni Egyetem Klinikai Kozpont
City
Debrecen
ZIP/Postal Code
4032
Country
Hungary
Facility Name
Borsod-Abauj-Zemplen Megyei Korhaz es Egyetemi Oktato Korhaz
City
Miskolc
ZIP/Postal Code
3526
Country
Hungary
Facility Name
Szent Borbala Korhaz
City
Tatabánya
ZIP/Postal Code
2800
Country
Hungary
Facility Name
Zala Megyei Szent Rafael Korhaz
City
Zalaegerszeg
ZIP/Postal Code
8900
Country
Hungary
Facility Name
HCG City Cancer Centre
City
Vijayawada
State/Province
Andhra Pradesh
ZIP/Postal Code
520002
Country
India
Facility Name
State Cancer Institute, Indira Gandhi Institute of Medical Sciences (IGIMS)
City
Patna
State/Province
Bihar
ZIP/Postal Code
800014
Country
India
Facility Name
Gujarat Cancer & Research Inst.
City
Ahmadabad CITY
State/Province
Gujarat
ZIP/Postal Code
380016
Country
India
Facility Name
Hemato Oncology Clinic Ahmedabad Pvt Ltd
City
Ahmadabad
State/Province
Gujarat
ZIP/Postal Code
380054
Country
India
Facility Name
HCG Cancer Center
City
Ahmedabad
State/Province
Gujarat
ZIP/Postal Code
380060
Country
India
Facility Name
Nirmal Hospital
City
Surat
State/Province
Gujarat
ZIP/Postal Code
395002
Country
India
Facility Name
Kiran Hospital Multi Super Speciality Hospital and Research Center
City
Surat
State/Province
Gujarat
ZIP/Postal Code
395004
Country
India
Facility Name
Himalaya Cancer Hospital & Research Institute
City
Vadodara
State/Province
Gujarat
ZIP/Postal Code
390020
Country
India
Facility Name
Kailash Cancer Hospital and Research Center
City
Vadodara
State/Province
Gujarat
ZIP/Postal Code
391760
Country
India
Facility Name
KLES Dr Prabhakar Kore Hospital and Medical Research Centre
City
Belagavi
State/Province
Karnataka
ZIP/Postal Code
590010
Country
India
Facility Name
Sujan Surgical Cancer Hospital And Amravati Cancer Foundation
City
Amravati
State/Province
Maharashtra
ZIP/Postal Code
444606
Country
India
Facility Name
Kolhapur Cancer Centre
City
Kolhapur
State/Province
Maharashtra
ZIP/Postal Code
416234
Country
India
Facility Name
Tata Memorial Hospital
City
Mumbai
State/Province
Maharashtra
ZIP/Postal Code
400013
Country
India
Facility Name
Government Medical College
City
Nagpur
State/Province
Maharashtra
ZIP/Postal Code
440003
Country
India
Facility Name
HCG NCHRI Cancer Center
City
Nagpur
State/Province
Maharashtra
ZIP/Postal Code
440026
Country
India
Facility Name
Shalinitai Meghe Medical College and Hospital
City
Nagpur
State/Province
Maharashtra
ZIP/Postal Code
441110
Country
India
Facility Name
HCG Manavata Cancer Centre
City
Nashik
State/Province
Maharashtra
ZIP/Postal Code
422002
Country
India
Facility Name
Chopda Medicare & Research Centre pvt. Ltd
City
Nashik
State/Province
Maharashtra
ZIP/Postal Code
422005
Country
India
Facility Name
Apex Wellness Hospital
City
Nashik
State/Province
Maharashtra
ZIP/Postal Code
422009
Country
India
Facility Name
Sahyadri Speciality Hospital
City
Pune City
State/Province
Maharashtra
ZIP/Postal Code
411004
Country
India
Facility Name
Sahyadri Super Specialty Hospital Hadapsar
City
Pune
State/Province
Maharashtra
ZIP/Postal Code
411028
Country
India
Facility Name
Lokmanya Holistic Cancer Care and Research Center (LMRC)
City
Pune
State/Province
Maharashtra
ZIP/Postal Code
411033
Country
India
Facility Name
All India Institute of Medical Sciences, Bhubaneswar
City
Bhubaneswar
State/Province
Odisha
ZIP/Postal Code
751019
Country
India
Facility Name
Erode Cancer Centre
City
Erode
State/Province
Tamil NADU
ZIP/Postal Code
638012
Country
India
Facility Name
Christian Medical College-Ranipet Campus
City
Ratnagiri Kilminnal
State/Province
Tamil NADU
ZIP/Postal Code
632517
Country
India
Facility Name
King George Medical University (KGMU)
City
Lucknow
State/Province
Uttar Pradesh
ZIP/Postal Code
226003
Country
India
Facility Name
Institute of Post Graduate Medical Education and Research (IPGMER) and SSKM Hospital
City
Kolkata
State/Province
WEST Bengal
ZIP/Postal Code
700020
Country
India
Facility Name
Health Point Hospital - Kolkata
City
Kolkata
State/Province
WEST Bengal
ZIP/Postal Code
700025
Country
India
Facility Name
Cork University Hospital
City
Cork
ZIP/Postal Code
T12 DC4A
Country
Ireland
Facility Name
Bon Secours Hospital; Oncology
City
Cork
ZIP/Postal Code
T12 DV56
Country
Ireland
Facility Name
St Vincents University Hospital
City
Dublin
ZIP/Postal Code
D04 T6F4
Country
Ireland
Facility Name
St James Hospital; Cardiac Research
City
Dublin
ZIP/Postal Code
D08 NHY1
Country
Ireland
Facility Name
Beaumont Hospital
City
Dublin
ZIP/Postal Code
D09 V2N0
Country
Ireland
Facility Name
Galway University Hospital
City
Galway
ZIP/Postal Code
H71 YR71
Country
Ireland
Facility Name
Mid- Western Regional Hospital Limerick
City
Limerick
ZIP/Postal Code
V94 F858
Country
Ireland
Facility Name
Waterford Regional Hospital; Department Of Medical Oncology
City
Waterford
ZIP/Postal Code
X91 ER8E
Country
Ireland
Facility Name
Shamir Medical Center Assaf Harofeh
City
Beer Jacob
ZIP/Postal Code
0073100
Country
Israel
Facility Name
Soroka University Medical Centre
City
Beer Sheva
ZIP/Postal Code
8410101
Country
Israel
Facility Name
Sheba Medical Center - PPDS
City
Ramat-Gan
ZIP/Postal Code
5262000
Country
Israel
Facility Name
Tel-Aviv Sourasky Medical Center
City
Tel Aviv
ZIP/Postal Code
6423906
Country
Israel
Facility Name
Azienda Ospedaliera Universitaria Senese
City
Siena
State/Province
Abruzzo
ZIP/Postal Code
53100
Country
Italy
Facility Name
Azienda Ospedaliera di Rilievo Nazionale e di Alta Specialita San Giuseppe Moscati
City
Avellino
State/Province
Campania
ZIP/Postal Code
83100
Country
Italy
Facility Name
Istituto Nazionale per lo Studio e la Cura dei Tumori Fondazione G. Pascale
City
Napoli
State/Province
Campania
ZIP/Postal Code
80131
Country
Italy
Facility Name
Azienda Ospedaliero Universitaria di Bologna Policlinico S.Orsola-Malpighi
City
Bologna
State/Province
Emilia-Romagna
ZIP/Postal Code
40138
Country
Italy
Facility Name
Istituto Scientifico Romagnolo Per Lo Studio E La Cura Dei Tumori IRST - PPDS
City
Meldola
State/Province
Emilia-Romagna
ZIP/Postal Code
47014
Country
Italy
Facility Name
Arcispedale Santa Maria Nuova; Oncologia
City
Reggio Emilia
State/Province
Emilia-Romagna
ZIP/Postal Code
42100
Country
Italy
Facility Name
Fondazione Policlinico Universitario A Gemelli; Farmacia Interna
City
Roma
State/Province
Emilia-Romagna
ZIP/Postal Code
00168
Country
Italy
Facility Name
Istituto Nazionale Tumori Regina Elena
City
Roma
State/Province
Lazio
ZIP/Postal Code
00144
Country
Italy
Facility Name
Ospedale Policlinico San Martino
City
Genova
State/Province
Liguria
ZIP/Postal Code
16132
Country
Italy
Facility Name
Ospedale San Giuseppe; Oncologia Medica
City
Milano
State/Province
Lombardia
ZIP/Postal Code
20123
Country
Italy
Facility Name
Ospedale San Raffaele S.r.l. - PPDS
City
Milano
State/Province
Lombardia
ZIP/Postal Code
20132
Country
Italy
Facility Name
ASST Grande Ospedale Metropolitano Niguarda - Presidio Ospedaliero Ospedale Niguarda Ca' Granda
City
Milano
State/Province
Lombardia
ZIP/Postal Code
20162
Country
Italy
Facility Name
Istituto Clinico Humanitas
City
Rozzano (MI)
State/Province
Lombardia
ZIP/Postal Code
20089
Country
Italy
Facility Name
Azienda Ospedaliero Universitaria Ospedali Riuniti
City
Torrette Di Ancona
State/Province
Marche
ZIP/Postal Code
60126
Country
Italy
Facility Name
Azienda Ospedaliera Universitaria Careggi
City
Florence
State/Province
Toscana
ZIP/Postal Code
50134
Country
Italy
Facility Name
Ospedale Civile - Livorno
City
Livorno
State/Province
Toscana
ZIP/Postal Code
57124
Country
Italy
Facility Name
Azienda Ospedaliero Universitaria Pisana
City
Pisa
State/Province
Toscana
ZIP/Postal Code
56126
Country
Italy
Facility Name
Nuovo Ospedale di Prato S. Stefano - Azienda USL Toscana Centro
City
Prato
State/Province
Toscana
ZIP/Postal Code
59100
Country
Italy
Facility Name
IRCCS Ospedale Sacro Cuore Don Calabria
City
Negrar
State/Province
Veneto
ZIP/Postal Code
37024
Country
Italy
Facility Name
St. Luke's International Hospital
City
Chuo
ZIP/Postal Code
104-0044
Country
Japan
Facility Name
Fukushima Medical University Hospital
City
Fukushima
ZIP/Postal Code
960-1295
Country
Japan
Facility Name
Hiroshima University Hospital
City
Hiroshima
ZIP/Postal Code
734-8551
Country
Japan
Facility Name
National Hospital Organization Hokkaido Cancer Center
City
Hokkaido
ZIP/Postal Code
003-0804
Country
Japan
Facility Name
Social Medical Corporation Hakuaikai Sagara Hospital
City
Kagoshima
ZIP/Postal Code
892-0833
Country
Japan
Facility Name
Tokai University Hospital
City
Kanagawa
ZIP/Postal Code
259-1193
Country
Japan
Facility Name
Kumamoto University Hospital
City
Kumamoto
ZIP/Postal Code
860-8556
Country
Japan
Facility Name
Nahanishi Clinic
City
Naha-shi
ZIP/Postal Code
901-0154
Country
Japan
Facility Name
National Hospital Organization Osaka National Hospital
City
Osaka
ZIP/Postal Code
540-0006
Country
Japan
Facility Name
Osaka International Cancer Institute
City
Osaka
ZIP/Postal Code
541-8567
Country
Japan
Facility Name
Saitama Cancer Center
City
Saitama
ZIP/Postal Code
362-0806
Country
Japan
Facility Name
The Cancer Institute Hospital of Japanese Foundation For Cancer Research
City
Tokyo
ZIP/Postal Code
135-8550
Country
Japan
Facility Name
International Cancer Institute (ICI)
City
Eldoret
ZIP/Postal Code
30100
Country
Kenya
Facility Name
Aga Khan University Hospital
City
Nairobi
ZIP/Postal Code
00100
Country
Kenya
Facility Name
Chungbuk National University Hospital
City
Cheongju-si
ZIP/Postal Code
28644
Country
Korea, Republic of
Facility Name
Soon Chun Hyang University Cheonan Hospital
City
Dongnam-gu, Cheonan-si
ZIP/Postal Code
31151
Country
Korea, Republic of
Facility Name
Yonsei University Wonju Severance Christian Hospital
City
Gangwon-do
ZIP/Postal Code
26426
Country
Korea, Republic of
Facility Name
National Cancer Centre
City
Gyeonggi-do
ZIP/Postal Code
10408
Country
Korea, Republic of
Facility Name
CHA Bundang Medical Center
City
Gyeonggi-do
ZIP/Postal Code
13496
Country
Korea, Republic of
Facility Name
Gachon University Gil Medical Center
City
Incheon
ZIP/Postal Code
21565
Country
Korea, Republic of
Facility Name
Inha University Hospital
City
Incheon
ZIP/Postal Code
22332
Country
Korea, Republic of
Facility Name
Seoul National University Bundang Hospital
City
Seongnam-si
ZIP/Postal Code
463-707
Country
Korea, Republic of
Facility Name
Korea University Anam Hospital
City
Seoul
ZIP/Postal Code
02841
Country
Korea, Republic of
Facility Name
Seoul National University Hospital
City
Seoul
ZIP/Postal Code
03080
Country
Korea, Republic of
Facility Name
Severance Hospital, Yonsei University Health System
City
Seoul
ZIP/Postal Code
03722
Country
Korea, Republic of
Facility Name
Asan Medical Center - PPDS
City
Seoul
ZIP/Postal Code
05505
Country
Korea, Republic of
Facility Name
Samsung Medical Center - PPDS
City
Seoul
ZIP/Postal Code
06351
Country
Korea, Republic of
Facility Name
Korea University Guro Hospital
City
Seoul
ZIP/Postal Code
08308
Country
Korea, Republic of
Facility Name
The Catholic University of Korea Seoul St. Mary?s Hospital
City
Seoul
ZIP/Postal Code
6591
Country
Korea, Republic of
Facility Name
Gangnam Severance Hospital, Yonsei University Health System
City
Seoul
Country
Korea, Republic of
Facility Name
Ajou University Hospital
City
Suwon City
ZIP/Postal Code
443-721
Country
Korea, Republic of
Facility Name
Ulsan University Hosiptal
City
Ulsan
ZIP/Postal Code
44033
Country
Korea, Republic of
Facility Name
Pauls Stradins Clinical University Hospital
City
R?ga
ZIP/Postal Code
LV-1002
Country
Latvia
Facility Name
Hospital Kuala Lumpur
City
Kuala Lumpur
State/Province
FED. Territory OF Kuala Lumpur
ZIP/Postal Code
50586
Country
Malaysia
Facility Name
University Malaya Medical Centre
City
Kuala Lumpur
State/Province
FED. Territory OF Kuala Lumpur
ZIP/Postal Code
59100
Country
Malaysia
Facility Name
National Cancer Institute IKN
City
Putrajaya
State/Province
Federal Territory OF Putrajaya
ZIP/Postal Code
62250
Country
Malaysia
Facility Name
Pantai Hospital Sungai Petani
City
Sungai Petani
State/Province
Kedah
ZIP/Postal Code
08000
Country
Malaysia
Facility Name
Sarawak General Hospital
City
Kuching
State/Province
Sarawak
ZIP/Postal Code
93586
Country
Malaysia
Facility Name
Beacon International Specialist Centre
City
Petaling Jaya, Selangor
State/Province
Selangor
ZIP/Postal Code
46050
Country
Malaysia
Facility Name
Hospital Pulau Pinang
City
Penang
ZIP/Postal Code
10990
Country
Malaysia
Facility Name
Centro de Investigación en Artritis y Osteoporosis - PPDS
City
Mexicali
State/Province
BAJA California
ZIP/Postal Code
21200
Country
Mexico
Facility Name
Office of Alma Magdalena Astorga-Ramos, MD
City
Gómez Palacio
State/Province
Durango
ZIP/Postal Code
35000
Country
Mexico
Facility Name
Dr. José Luis González Trujillo
City
León de Los Aldama
State/Province
Guanajuato
ZIP/Postal Code
37000
Country
Mexico
Facility Name
Hospital Civil Fray Antonio Alcalde
City
Guadalajara
State/Province
Jalisco
ZIP/Postal Code
44280
Country
Mexico
Facility Name
Health Pharma Professional Research
City
Cdmx
State/Province
Mexico CITY (federal District)
ZIP/Postal Code
03100
Country
Mexico
Facility Name
Centro Hemato-Oncologico Privado CHOP
City
Toluca
State/Province
Mexico CITY (federal District)
ZIP/Postal Code
50120
Country
Mexico
Facility Name
Accelerium S. de R.L. de C.V.
City
Monterrey
State/Province
Nuevo LEON
ZIP/Postal Code
64000
Country
Mexico
Facility Name
Hospital Universitario Dr. Jose Eleuterio Gonzalez
City
Monterrey
State/Province
Nuevo LEON
Country
Mexico
Facility Name
Oaxaca Site Management Organization
City
Oaxaca de Juárez
State/Province
Oaxaca
ZIP/Postal Code
68000
Country
Mexico
Facility Name
Centro de Investigacion Clinica de Oaxaca
City
Oaxaca de Juárez
State/Province
Oaxaca
ZIP/Postal Code
68020
Country
Mexico
Facility Name
Unidad Médica Onco-Hematológica
City
Heroica Puebla de Zaragoza
State/Province
Puebla
ZIP/Postal Code
72424
Country
Mexico
Facility Name
Clínica Integral Internacional de Oncología S de RL de CV
City
Heroica Puebla de Zaragoza
State/Province
Puebla
ZIP/Postal Code
72530
Country
Mexico
Facility Name
Investigación Médica de Alta Especialidad
City
Santiago de Querétaro
State/Province
Queretaro
ZIP/Postal Code
76090
Country
Mexico
Facility Name
Neurociencias Estudios Clinicos S.C.
City
Culiacán
State/Province
Sinaloa
ZIP/Postal Code
80020
Country
Mexico
Facility Name
Merida | Investigacion Clinica
City
Mérida
State/Province
Yucatan
ZIP/Postal Code
97125
Country
Mexico
Facility Name
Centro de Investigacion Medica Aguascalientes
City
Aguascalientes
ZIP/Postal Code
20116
Country
Mexico
Facility Name
Centro Oncologico Alianza XXI
City
Mexico
Country
Mexico
Facility Name
Oncológico Potosino
City
San Luis Potosí
ZIP/Postal Code
78209
Country
Mexico
Facility Name
HAGAZIEKENHUIS; Interne Geneeskunde
City
'S-Gravenhage
ZIP/Postal Code
2545 AA
Country
Netherlands
Facility Name
Catharina Hospital; Research Oncologie
City
Eindhoven
ZIP/Postal Code
5623 EJ
Country
Netherlands
Facility Name
Maastricht University Medical Center
City
Maastricht
ZIP/Postal Code
6229 HX
Country
Netherlands
Facility Name
Zuyderland Medisch Centrum; Trialbureau Poli Interne Geneeskunde
City
Sittard-Geleen
ZIP/Postal Code
6162 BG
Country
Netherlands
Facility Name
Viecuri Medisch Centrum
City
Venlo
ZIP/Postal Code
5912 BL
Country
Netherlands
Facility Name
PHI Clinical Hospital Dr Trifun Panovski Bitola
City
Bitola
ZIP/Postal Code
7000
Country
North Macedonia
Facility Name
Acibadem Sistina Hospital
City
Skopje
ZIP/Postal Code
1000
Country
North Macedonia
Facility Name
PHI University Clinic of Radiotherapy and Oncology; Breast malignancy
City
Skopje
ZIP/Postal Code
1000
Country
North Macedonia
Facility Name
Hospital Nacional Daniel A Carrion
City
Bellavista
ZIP/Postal Code
7016
Country
Peru
Facility Name
Hospital Militar Central
City
Jesus Maria
ZIP/Postal Code
Lima 11
Country
Peru
Facility Name
Hospital Central Fuerza Aerea Del Peru
City
Lima
ZIP/Postal Code
15046
Country
Peru
Facility Name
Clínica Santa Beatriz
City
Lima
ZIP/Postal Code
15072
Country
Peru
Facility Name
Oncologia S.A.C. - Instituto Peruano de Oncología & Radioterapia
City
Lima
ZIP/Postal Code
27
Country
Peru
Facility Name
Oncosalud Sac; Oncología
City
Lima
ZIP/Postal Code
41
Country
Peru
Facility Name
Instituto Nacional de Enfermedades Neoplasicas
City
Lima
ZIP/Postal Code
Lima 34
Country
Peru
Facility Name
Clinica Peruana Americana
City
Trujillo
ZIP/Postal Code
13011
Country
Peru
Facility Name
Dr Pablo O Torre Memorial Hospital
City
Bacolod City
ZIP/Postal Code
6100
Country
Philippines
Facility Name
Baguio General Hospital and Medical Center
City
Baguio City
ZIP/Postal Code
2600
Country
Philippines
Facility Name
Saint Louis University Hospital of Sacred Heart
City
Baguio City
ZIP/Postal Code
2600
Country
Philippines
Facility Name
Metro Davao Medical and Research Center
City
Davao City
ZIP/Postal Code
8000
Country
Philippines
Facility Name
St. Paul's Hospital
City
Iloilo City
ZIP/Postal Code
5000
Country
Philippines
Facility Name
University of Santo Tomas Hospital; Pharmacy
City
Manila
ZIP/Postal Code
1015
Country
Philippines
Facility Name
Cardinal Santos Medical Center; Department of Internal Medicine, Section of Endocrinology
City
Manila
ZIP/Postal Code
1503
Country
Philippines
Facility Name
The Medical City; Oncology
City
Pasig City
ZIP/Postal Code
1605
Country
Philippines
Facility Name
East Avenue Medical Center; Breast Care Center
City
Quezon City
ZIP/Postal Code
1101
Country
Philippines
Facility Name
St. Luke's Medical Center - Quezon City
City
Quezon City
ZIP/Postal Code
1102
Country
Philippines
Facility Name
Centrum Onkologii im. Prof. F. Lukaszczyka w Bydgoszczy
City
Bydgoszcz
ZIP/Postal Code
85-796
Country
Poland
Facility Name
Szpital Morski Im. Pck; Oncology & Radiotherapy Dept
City
Gdynia
ZIP/Postal Code
81-519
Country
Poland
Facility Name
Narodowy Instytut Onkologii im. M.Sk?odowskiej-Curie - Pa?stwowy Instytut Badawczy Oddzia? Gliwice
City
Gliwice
ZIP/Postal Code
44-101
Country
Poland
Facility Name
Regionalny Szpital Specjalistyczny im. W. Bieganskiego; Oddzia? Onkologii Klinicznej
City
Grudziadz
ZIP/Postal Code
86-300
Country
Poland
Facility Name
Centrum Terapii Wspolczesnej
City
Lodz
ZIP/Postal Code
90-338
Country
Poland
Facility Name
Centrum Onkologii Ziemi LUBELSKIEJ im. Sw Jana z Dukli, I oddz. Chemioterapii
City
Lublin
ZIP/Postal Code
20-090
Country
Poland
Facility Name
Centrum Medyczne Pratia Poznan
City
Skórzewo
ZIP/Postal Code
60-185
Country
Poland
Facility Name
Narodowy Instytut Onkologii - Panstwowy Instytut Badawczy, Oddzia? w Krakowie
City
Warszawa
ZIP/Postal Code
02-781
Country
Poland
Facility Name
Narodowy Instytut Onkologii im. Marii Sk?odowskiej-Curie - Pa?stwowy Instytut Badawczy
City
Warszawa
ZIP/Postal Code
02-781
Country
Poland
Facility Name
Hospital Senhora da Oliveira ? Guimaraes, E.P.E
City
Guimarães
ZIP/Postal Code
4835-044
Country
Portugal
Facility Name
Champalimaud Cancer Center
City
Lisboa
ZIP/Postal Code
1400-038
Country
Portugal
Facility Name
Hospital da Luz
City
Lisboa
ZIP/Postal Code
1500-650
Country
Portugal
Facility Name
Centro Hospitalar Lisboa Norte, E.P.E. ? Hospital de Santa Maria; Servicos Farmaceuticos
City
Lisboa
ZIP/Postal Code
1649-035
Country
Portugal
Facility Name
Instituto Português de Oncologia de Lisboa Francisco Gentil, E.P.E.
City
Lisbon
ZIP/Postal Code
1050-034
Country
Portugal
Facility Name
Hospital Beatriz Angelo
City
Loures
ZIP/Postal Code
2674-514
Country
Portugal
Facility Name
Centro Hospitalar do Porto ? Hospital de Santo António; Oncologia
City
Porto
ZIP/Postal Code
4099-001
Country
Portugal
Facility Name
Instituto Portugues de Oncologia Do Porto Francisco Gentil Epe
City
Porto
ZIP/Postal Code
4200-072
Country
Portugal
Facility Name
Centro Hospitalar de Vila Nova de Gaia / Espinho E.P.E
City
Vila Nova de Gaia
ZIP/Postal Code
4434-502
Country
Portugal
Facility Name
Centro Hospitalar Trás Os Montes E Alto Douro EPE
City
Vila Real
ZIP/Postal Code
5000-508
Country
Portugal
Facility Name
Spitalul Clinic de Obstetrica si Ginecologie Filantropia; Sectorul 1 BUCURE?TI
City
Bucure?ti
ZIP/Postal Code
011171
Country
Romania
Facility Name
Prof Dr I Chiricuta Institute of Oncology; Oncology Department
City
Cluj-napoca
ZIP/Postal Code
400015
Country
Romania
Facility Name
Medisprof SRL
City
Cluj-Napoca
ZIP/Postal Code
400058
Country
Romania
Facility Name
Onco Clinic Consult SA
City
Craiova
ZIP/Postal Code
200094
Country
Romania
Facility Name
Oncology Center Sf. Nectarie
City
Craiova
ZIP/Postal Code
200347
Country
Romania
Facility Name
Institutul Regional de Oncologie Iasi
City
Iasi
ZIP/Postal Code
700483
Country
Romania
Facility Name
Timisoara Emergency County Clinical Hospital
City
Timi?oara
ZIP/Postal Code
300595
Country
Romania
Facility Name
Institute for Oncology and Radiology of Serbia
City
Belgrade
ZIP/Postal Code
11000
Country
Serbia
Facility Name
University Hospital Medical Center Bezanijska kosa
City
Belgrade
ZIP/Postal Code
11080
Country
Serbia
Facility Name
Health Center Kladovo
City
Kladovo
ZIP/Postal Code
19320
Country
Serbia
Facility Name
Clinical Center Kragujevac
City
Kragujevac
ZIP/Postal Code
34000
Country
Serbia
Facility Name
Clinical Center Nis
City
NIS
ZIP/Postal Code
18000
Country
Serbia
Facility Name
Oncology Institute of Vojvodina
City
Sremska Kamenica
ZIP/Postal Code
21204
Country
Serbia
Facility Name
General Hospital Djordje Joanovic - Zrenjanin
City
Zrenjanin
ZIP/Postal Code
23000
Country
Serbia
Facility Name
Univerzitna nemocnica s poliklinikou Milosrdni bratia spol s r o
City
Bratislava
ZIP/Postal Code
811 06
Country
Slovakia
Facility Name
Onkologicky ustav sv. Alzbety, s.r.o.
City
Bratislava
ZIP/Postal Code
812 50
Country
Slovakia
Facility Name
Narodny onkologicky ustav
City
Bratislava
ZIP/Postal Code
833 10
Country
Slovakia
Facility Name
Vychodoslovensky onkologicky ustav
City
Kosice
ZIP/Postal Code
041 91
Country
Slovakia
Facility Name
Institute of Oncology Ljubljana
City
Ljubljana
ZIP/Postal Code
1000
Country
Slovenia
Facility Name
Cape Town Oncology Trials
City
Cape Town
ZIP/Postal Code
7570
Country
South Africa
Facility Name
Cancercare Rondebosch Oncology
City
Cape Town
ZIP/Postal Code
7700
Country
South Africa
Facility Name
WITS Clinical Research Site PPDS
City
City Of Johannesburg
ZIP/Postal Code
2193
Country
South Africa
Facility Name
Sandton Oncology Medical Group (Pty) Ltd
City
City Of Johannesburg
ZIP/Postal Code
2196
Country
South Africa
Facility Name
Excellentis Clinical Trial Consultants; Clinical Research
City
George
ZIP/Postal Code
6529
Country
South Africa
Facility Name
Medical Oncology Centre of Rosebank; Oncology
City
Johannesburg
ZIP/Postal Code
2196
Country
South Africa
Facility Name
Southern Cross Research South Africa (PTY) LTD
City
Mogale City
ZIP/Postal Code
1724
Country
South Africa
Facility Name
Langenhoven Drive Oncology Centre
City
Port Elizabeth
ZIP/Postal Code
6045
Country
South Africa
Facility Name
Wilgers Oncology Centre
City
Pretoria
ZIP/Postal Code
0001
Country
South Africa
Facility Name
Eastleigh Breast Care Centre
City
Pretoria
ZIP/Postal Code
0081
Country
South Africa
Facility Name
Hospital General Universitario de Elche
City
Elche
State/Province
Alicante
ZIP/Postal Code
03203
Country
Spain
Facility Name
ICO Badalona-H.U. Germans Trias i Pujol
City
Badalona
State/Province
Barcelona
ZIP/Postal Code
08916
Country
Spain
Facility Name
ALTHAIA Xarxa Assistencial de Manresa
City
Manresa
State/Province
Barcelona
ZIP/Postal Code
08243
Country
Spain
Facility Name
Corporacio Sanitaria Parc Tauli
City
Sabadell
State/Province
Barcelona
ZIP/Postal Code
08208
Country
Spain
Facility Name
Hospital HM Nuestra Señora de la Esperanza
City
Santiago de Compostela
State/Province
Burgos
ZIP/Postal Code
15705
Country
Spain
Facility Name
Hospital de Jerez
City
Jerez De La Frontera
State/Province
Cadiz
ZIP/Postal Code
11407
Country
Spain
Facility Name
Consorcio Hospitalario Provincial de Castellon
City
Castellon DE LA Plana/castello DE LA Plana
State/Province
Castellon
ZIP/Postal Code
12002
Country
Spain
Facility Name
Hospital Universitario Reina Sofia; Servicio de Farmacia
City
Córdoba
State/Province
Cordoba
ZIP/Postal Code
14004
Country
Spain
Facility Name
Hospital Universitario de Donostia
City
Donostia
State/Province
Guipuzcoa
ZIP/Postal Code
20080
Country
Spain
Facility Name
Hospital Universitario Son Espases
City
Palma de Mallorca
State/Province
Islas Baleares
ZIP/Postal Code
07120
Country
Spain
Facility Name
Hospital Son Llatzer
City
Palma de Mallorca
State/Province
Islas Baleares
ZIP/Postal Code
07198
Country
Spain
Facility Name
Hospital Universitario A Coruña
City
Coruna
State/Province
LA Coruña
ZIP/Postal Code
15006
Country
Spain
Facility Name
CHUS H Clinico U de Santiago
City
Santiago de Compostela
State/Province
LA Coruña
ZIP/Postal Code
15706
Country
Spain
Facility Name
Hospital Universitario Insular de Gran Canaria
City
Las Palmas de Gran Canaria
State/Province
LAS Palmas
ZIP/Postal Code
35016
Country
Spain
Facility Name
Hospital Universitari Arnau de Vilanova
City
Lleida
State/Province
Lerida
ZIP/Postal Code
25198
Country
Spain
Facility Name
Hospital Universitario Fundación Alcorcón
City
Alcorcon
State/Province
Madrid
ZIP/Postal Code
28922
Country
Spain
Facility Name
Hospital Universitario Puerta de Hierro - Majadahonda
City
Majadahonda
State/Province
Madrid
ZIP/Postal Code
28220
Country
Spain
Facility Name
Complejo Hospitalario de Navarra; Servicio de Farmacia
City
Pamplona
State/Province
Navarra
ZIP/Postal Code
31008
Country
Spain
Facility Name
CHUVI ? H.U. Alvaro Cunqueiro
City
Vigo
State/Province
Pontevedra
ZIP/Postal Code
36312
Country
Spain
Facility Name
Hospital Nuestra Senora de Valme
City
Seville
State/Province
Sevilla
ZIP/Postal Code
41014
Country
Spain
Facility Name
Hospital Universitario Virgen Macarena
City
Seville
State/Province
Sevilla
ZIP/Postal Code
41071
Country
Spain
Facility Name
Hospital Universitari Sant Joan de Reus
City
Reus
State/Province
Tarragona
ZIP/Postal Code
43204
Country
Spain
Facility Name
Hospital Universitario de Canarias
City
S. Cristobal De La Laguna
State/Province
Tenerife
ZIP/Postal Code
38320
Country
Spain
Facility Name
Hospital Universitario Basurto
City
Bilbao
State/Province
Vizcaya
ZIP/Postal Code
48013
Country
Spain
Facility Name
Complejo Hospitalario Universitario de Albacete
City
Albacete
ZIP/Postal Code
2006
Country
Spain
Facility Name
Hospital General Universitario de Alicante
City
Alicante
ZIP/Postal Code
03010
Country
Spain
Facility Name
Hospital Universitario San Juan
City
Alicante
ZIP/Postal Code
03550
Country
Spain
Facility Name
Hospital Nuestra Señora de Sonsoles
City
Avila
ZIP/Postal Code
05004
Country
Spain
Facility Name
Hospital del Mar
City
Barcelona
ZIP/Postal Code
08003
Country
Spain
Facility Name
Clinica Tres Torres
City
Barcelona
ZIP/Postal Code
08017
Country
Spain
Facility Name
Hospital de la Santa Creu i Sant Pau
City
Barcelona
ZIP/Postal Code
08025
Country
Spain
Facility Name
Hospital Universitario Quiron Dexeus
City
Barcelona
ZIP/Postal Code
08028
Country
Spain
Facility Name
Hospital Universitari Vall d'Hebron
City
Barcelona
ZIP/Postal Code
08035
Country
Spain
Facility Name
Hospital Clinic de Barcelona
City
Barcelona
ZIP/Postal Code
08036
Country
Spain
Facility Name
Hospital de San Pedro de Alcantara
City
Caceres
ZIP/Postal Code
10003
Country
Spain
Facility Name
Hospital Puerta del Mar
City
Cadiz
ZIP/Postal Code
11009
Country
Spain
Facility Name
Institut Catala d'Oncologia Girona
City
Girona
ZIP/Postal Code
17007
Country
Spain
Facility Name
Hospital Universitario Clínico San Cecilio
City
Granada
ZIP/Postal Code
18007
Country
Spain
Facility Name
Hospital Universitario Virgen de Las Nieves
City
Granada
ZIP/Postal Code
18012
Country
Spain
Facility Name
Hospital Universitario Juan Ramon Jimenez
City
Huelva
ZIP/Postal Code
21005
Country
Spain
Facility Name
Hospital Universitario de Jaen
City
Jaen
ZIP/Postal Code
23007
Country
Spain
Facility Name
Hospital General Universitario Gregorio Marañon
City
Madrid
ZIP/Postal Code
28007
Country
Spain
Facility Name
Hospital Universitario La Paz
City
Madrid
ZIP/Postal Code
280146
Country
Spain
Facility Name
Clinica Universidad Navarra; Servicio de Farmacia
City
Madrid
ZIP/Postal Code
28027
Country
Spain
Facility Name
Hospital Universitario Infanta Leonor
City
Madrid
ZIP/Postal Code
28031
Country
Spain
Facility Name
Centro Oncologioco MD Anderson Internacional; Servicio de Farmacia
City
Madrid
ZIP/Postal Code
28033
Country
Spain
Facility Name
Hospital Universitario Ramon y Cajal
City
Madrid
ZIP/Postal Code
28034
Country
Spain
Facility Name
Hospital Clinico San Carlos
City
Madrid
ZIP/Postal Code
28040
Country
Spain
Facility Name
Hospital Universitario Fundacion Jimenez Diaz.
City
Madrid
ZIP/Postal Code
28040
Country
Spain
Facility Name
Hospital Ruber Internacional
City
Madrid
ZIP/Postal Code
28041
Country
Spain
Facility Name
Hospital Universitario 12 De Octubre
City
Madrid
ZIP/Postal Code
28041
Country
Spain
Facility Name
Hospital Universitario HM Sanchinarro ? CIOCC; Farmacia - Ensayos Clínicos
City
Madrid
ZIP/Postal Code
28050
Country
Spain
Facility Name
Hospital Universitario de Fuenlabrada
City
Madrid
ZIP/Postal Code
28942
Country
Spain
Facility Name
Hospital Universitario Virgen de la Victoria
City
Malaga
ZIP/Postal Code
29010
Country
Spain
Facility Name
Hospital General Universitario Morales Meseguer; Servicio de Neurología
City
Murcia
ZIP/Postal Code
30008
Country
Spain
Facility Name
Hospital Universitario Virgen de La Arrixaca
City
Murcia
ZIP/Postal Code
30120
Country
Spain
Facility Name
Hospital Universitario Virgen del Rocío
City
Sevilla
ZIP/Postal Code
41013
Country
Spain
Facility Name
Fundacion Instituto Valenciano de Oncologia (IVO)
City
Valencia
ZIP/Postal Code
46009
Country
Spain
Facility Name
Hospital Clinico Universitario de Valencia
City
Valencia
ZIP/Postal Code
46010
Country
Spain
Facility Name
Consorcio Hospital General Universitario de Valencia
City
Valencia
ZIP/Postal Code
46014
Country
Spain
Facility Name
Hospital Universitari i Politecnic La Fe de Valencia
City
Valencia
ZIP/Postal Code
46026
Country
Spain
Facility Name
Hospital Clinico Universitario de Valladolid; Servicio de Oncologia
City
Valladolid
ZIP/Postal Code
47005
Country
Spain
Facility Name
Hospital Universitario Miguel Servet
City
Zaragoza
ZIP/Postal Code
50009
Country
Spain
Facility Name
Länssjukhuset Ryhov
City
Jönköping
ZIP/Postal Code
551 85
Country
Sweden
Facility Name
Södersjukhuset
City
Stockholm
ZIP/Postal Code
11883
Country
Sweden
Facility Name
Sundsvalls sjukhus
City
Sundsvall
ZIP/Postal Code
851 86
Country
Sweden
Facility Name
Akademiska Sjukhuset
City
Uppsala
ZIP/Postal Code
751 85
Country
Sweden
Facility Name
Västmanlands sjukhus Västerås
City
Västerås
ZIP/Postal Code
72189
Country
Sweden
Facility Name
Tumorzentrum Aarau
City
Aarau
ZIP/Postal Code
5000
Country
Switzerland
Facility Name
Kantonsspital Baden
City
Baden
ZIP/Postal Code
5404
Country
Switzerland
Facility Name
Universitätsspital Basel
City
Basel
ZIP/Postal Code
4031
Country
Switzerland
Facility Name
Universitätsspital Bern; Departement Herz & Gefässe
City
Bern
ZIP/Postal Code
3010
Country
Switzerland
Facility Name
Hirslanden Salem-Spital
City
Bern
ZIP/Postal Code
3013
Country
Switzerland
Facility Name
Kantonsspital Graubuenden
City
Chur
ZIP/Postal Code
7000
Country
Switzerland
Facility Name
Luzerner Kantonsspital LUKS; Studienzentrale Onkologie
City
Luzern
ZIP/Postal Code
6000
Country
Switzerland
Facility Name
Hirslanden Klinik St. Anna Brustzentrum/Chirurgie
City
Luzern
ZIP/Postal Code
6006
Country
Switzerland
Facility Name
Kantonsspital St. Gallen
City
St. Gallen
ZIP/Postal Code
9007
Country
Switzerland
Facility Name
Spital STS AG Thun - Berner Oberland ; Onkologie Zentrum
City
Thun
ZIP/Postal Code
3600
Country
Switzerland
Facility Name
Kantonsspital Winterthur Medizin Pneumologie
City
Winterthur
ZIP/Postal Code
8400
Country
Switzerland
Facility Name
Brust-Zentrum Zürich AG Seefeldstrasse 214 Zürich
City
Zürich
ZIP/Postal Code
8008
Country
Switzerland
Facility Name
Koo Foundation Sun Yat-Sen Cancer Center
City
Beitou Dist.
ZIP/Postal Code
11259
Country
Taiwan
Facility Name
Changhua Christian Medical Foundation Changhua Christian Hospital
City
Changhua County
ZIP/Postal Code
50006
Country
Taiwan
Facility Name
Hsin-Chu Branch of National Taiwan University Hospital
City
Hsinchu City
ZIP/Postal Code
300
Country
Taiwan
Facility Name
Kaohsiung Medical University Chung-Ho Memorial Hospital
City
Kaohsiung City
ZIP/Postal Code
807
Country
Taiwan
Facility Name
Taipei Medical University Shuang Ho Hospital
City
New Taipei City
ZIP/Postal Code
23561
Country
Taiwan
Facility Name
China Medical University Hospital
City
Taichung
ZIP/Postal Code
40447
Country
Taiwan
Facility Name
National Cheng Kung University Hospital
City
Tainan
ZIP/Postal Code
70457
Country
Taiwan
Facility Name
Chi Mei Medical Cente
City
Tainan
ZIP/Postal Code
71044
Country
Taiwan
Facility Name
Taipei Veterans General Hospital
City
Taipei City
ZIP/Postal Code
112
Country
Taiwan
Facility Name
National Taiwan University Hospital
City
Taipei
ZIP/Postal Code
10002
Country
Taiwan
Facility Name
Mackay Memorial Hospital - Taipei Branch
City
Taipei
ZIP/Postal Code
104
Country
Taiwan
Facility Name
Tri-Service General Hospital
City
Taipei
ZIP/Postal Code
11490
Country
Taiwan
Facility Name
Chang Gung Memorial Hospital - Linkou
City
Taoyuan
ZIP/Postal Code
333
Country
Taiwan
Facility Name
Taichung Veterans General Hospital
City
Xitun Dist.
ZIP/Postal Code
40705
Country
Taiwan
Facility Name
Chulalongkorn Hospital; Medical Oncology
City
Bangkok
ZIP/Postal Code
10330
Country
Thailand
Facility Name
Ramathibodi Hospital
City
Bangkok
ZIP/Postal Code
10400
Country
Thailand
Facility Name
Siriraj Hospital, Mahidol University
City
Bangkok
ZIP/Postal Code
10700
Country
Thailand
Facility Name
Hacettepe Universitesi Tip Fakultesi Hastanesi
City
Ankara
ZIP/Postal Code
06100
Country
Turkey
Facility Name
Ankara City Hospital; Oncology
City
Ankara
ZIP/Postal Code
06800
Country
Turkey
Facility Name
Akdeniz University Medical Faculty
City
Antalya
ZIP/Postal Code
07059
Country
Turkey
Facility Name
Trakya University Medical Faculty
City
Edirne
ZIP/Postal Code
22030
Country
Turkey
Facility Name
Istanbul University Cerrahpasa Medical Faculty Hospital; Klinik Arast?rma Merkezi
City
Istanbul
ZIP/Postal Code
34096
Country
Turkey
Facility Name
T.C. Saglik Bakanligi Goztepe Prof. Dr. Suleyman Yalcin City Hospital
City
Istanbul
ZIP/Postal Code
34722
Country
Turkey
Facility Name
Izmir Medical Point Hospital
City
Izmir
ZIP/Postal Code
35101
Country
Turkey
Facility Name
Katip Celebi University- Izmir Ataturk Egitim ve Arastirma Hastanesi
City
Izmir
ZIP/Postal Code
35360
Country
Turkey
Facility Name
Kocaeli Universitesi Tip Fakultesi Arastirma ve Uygulama Hastanesi
City
Kocaeli
ZIP/Postal Code
41380
Country
Turkey
Facility Name
Ondokuz Mayis Universitesi Tip Fakultesi Hastanesi
City
Samsun
ZIP/Postal Code
55105
Country
Turkey
Facility Name
Acibadem Maslak Hastanesi Büyükdere
City
Sariyer/Istanbul
ZIP/Postal Code
34457
Country
Turkey
Facility Name
Baskent Universitesi - Adana Uygulama Ve Arastirma Merkezi
City
Sariçam
ZIP/Postal Code
01250
Country
Turkey
Facility Name
Acibadem Adana Hospital, Oncology Department
City
Seyhan/Adana
ZIP/Postal Code
01130
Country
Turkey
Facility Name
Dr. Abdurrahman Yurtaslan Ankara Onkoloji Egitim ve Arastirma Hastanesi
City
Yenimahalle
ZIP/Postal Code
06200
Country
Turkey
Facility Name
Acibadem Altunizade Hospital
City
Üsküdar
ZIP/Postal Code
34662
Country
Turkey
Facility Name
St Francis Hospital Nsambya
City
Kampala
Country
Uganda
Facility Name
Uganda Cancer Institute
City
Kampala
Country
Uganda
Facility Name
SI Institute for general and urgent surgery n.a. V.T.Zaitseva of NAMS of Ukraine
City
Kharkiv
State/Province
Kharkiv Governorate
ZIP/Postal Code
61103
Country
Ukraine
Facility Name
Municipal Non-profit Enterprise Odessa Regional Clinical Hospital of Odessa Regional Council
City
Odesa
State/Province
Kherson Governorate
ZIP/Postal Code
65025
Country
Ukraine
Facility Name
Communal Non-Profit Enterprise Chernihiv Medical Center of Modern Oncology of CRC
City
Chernihiv
State/Province
KIEV Governorate
ZIP/Postal Code
14029
Country
Ukraine
Facility Name
Regional Municipal Non-Commercial Enterprise Bukovynian Clinical Oncology Center
City
Chernivtsi
State/Province
KIEV Governorate
ZIP/Postal Code
58000
Country
Ukraine
Facility Name
Clinic Verum Expert LLC
City
Kyiv
State/Province
KIEV Governorate
ZIP/Postal Code
03039
Country
Ukraine
Facility Name
Communal Nonprofit Enterprise Kyiv City Clinical Oncological Center
City
Kyiv
State/Province
KIEV Governorate
Country
Ukraine
Facility Name
Medical Clinical Research Center of Medical Center LLC Health Clinic
City
Vinnytsia
State/Province
Podolia Governorate
ZIP/Postal Code
21009
Country
Ukraine
Facility Name
Kyiv Regional Oncological Dispensary
City
Kyiv
ZIP/Postal Code
04107
Country
Ukraine
Facility Name
Royal Sussex County Hospital
City
Brighton
ZIP/Postal Code
BN2 5BE
Country
United Kingdom
Facility Name
Royal Cornwall Hospital; Dept of Clinical Oncology
City
Cornwall
ZIP/Postal Code
TR1 3LQ
Country
United Kingdom
Facility Name
Leicester Royal Infirmary
City
Leicester
ZIP/Postal Code
LE1 5WW
Country
United Kingdom
Facility Name
Barts and The London School of Medicine and Dentistry - Barts Cancer Institute (BCI)-CECM
City
London
ZIP/Postal Code
0
Country
United Kingdom
Facility Name
University College London Hospitals; Clinical Research Facility
City
London
ZIP/Postal Code
W1T 7HA
Country
United Kingdom
Facility Name
The Christie NHS Foundation Trust
City
Manchester
ZIP/Postal Code
M20 4BX
Country
United Kingdom
Facility Name
Nottingham City Hospital
City
Nottingham
ZIP/Postal Code
NG5 1PB
Country
United Kingdom
Facility Name
Royal Preston Hospital
City
Preston
ZIP/Postal Code
PR2 9HT
Country
United Kingdom
12. IPD Sharing Statement
Plan to Share IPD
Yes
IPD Sharing Plan Description
For eligible studies, qualified researchers may request access to individual patient level data through the request platform (www.vivli.org). Further details on Roche's criteria for eligible studies are available here (https://vivli.org/ourmember/roche/).
For further details on Roche's Global Policy on the Sharing of Clinical Information and how to request access to related clinical study documents, see here (https://www.roche.com/innovation/process/clinical-trials/data-sharing/).
Learn more about this trial
A Study Evaluating the Efficacy and Safety of Adjuvant Giredestrant Compared With Physician's Choice of Adjuvant Endocrine Monotherapy in Participants With Estrogen Receptor-Positive, HER2-Negative Early Breast Cancer (lidERA Breast Cancer)
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