Reducing Pregnancy Risks: The Mastery Lifestyle Intervention (MLI)

This is an interventional prevention trial for Mental Health Wellness 1 focused on measuring Latina, Pregnancy, Mental Health, Corticotropin Releasing Hormone, Progesterone, Estriol, Gestational age, African American women Read More

Inclusion Criteria:

• Providing informed consent;
• Ability to read and speak English or Spanish
• Pregnant at 14-20 weeks gestation with one fetus, gestational dating will be reviewed before enrollment via ultrasound administered per standard of care
• Intrauterine pregnancy
• Self-identification as Latina of Mexican heritage
• Age 18 to 45 years
• Born in Mexico or U.S. born and currently living in the U.S.
• Medicaid or other government supported insurance
• Women who score 10 or greater on the Center for Epidemiological Studies Depression Scale (CES-D) OR 5 or greater on the Generalized Anxiety Disorder-7 scale (GAD-7), or 14 or > on the Perceived Stress Scale as administered by clinical staff of the participating provider
• Willingness to adhere to the MLI regimen or usual care regimen
• Women who develop GDM after enrollment in the study will remain in the study. °Development of hypertension or preeclampsia, pyelonephritis, or GDM will be considered an effect modifier in analysis of infant outcomes.

Exclusion Criteria:

After initial review of the electronic health record (EHR):

• Major systemic infections such as HIV, hepatitis
• <18 years of age
• Enrollment in a prenatal program such as the Nurse Family Partnership
• Severe cognitive or psychiatric impairment per judgment of providers, that precludes cooperation with study protocol
• Inability to read English or Spanish