Economic Incentives and vDOT for Latent Tuberculosis Infection
Latent Tuberculosis
About this trial
This is an interventional prevention trial for Latent Tuberculosis focused on measuring Video Directly Observed Therapy
Eligibility Criteria
Inclusion Criteria:
- 18 years old or older,
- diagnosed with latent TB and determined to be appropriate for latent TB treatment by participants clinicians
- reside in Baltimore metro area
- speaks English or Spanish, or a language for which there is a short form available via the Johns Hopkins Medicine Institutional Review Board
- prescribed 3 months Isoniazid/Rifapentine, prescribed 3 months Isoniazid/Rifampin, or 4 months Rifampin
Exclusion Criteria:
- younger than 18 years old
- diagnosed with active TB
- prescribed an alternative treatment regimen for latent TB
- pregnant women (as determined by non-study directed clinical evaluation; BCHD performs urine pregnancy testing on women of child bearing age when indicated)
- participant's spoken language does not have a translated long or short consent form
Sites / Locations
- Baltimore City Health Department, and Baltimore metropolitan area clinics and health departmentsRecruiting
Arms of the Study
Arm 1
Arm 2
Arm 3
Active Comparator
Active Comparator
Experimental
Usual Care
Video Directly Observed Therapy alone
Video Directly Observed Therapy plus Financial Incentives
Participants will receive routine (non-study directed) medical care for latent tuberculosis infection according to published guidelines, including medication, nurse case management, Tuberculosis health education, and toxicity assessments.
Participants in this group will receive the same treatments and education provided to Usual Care Control participants, however treatment will be viewed by video directly observed therapy (video-DOT)
Participants in this group will receive the same treatments and education provided to Usual Care Control participants, as well as treatment viewed by video DOT. This arm will also earn financial contingent incentives. Participants will receive incentive payments when a submitted video is monitored by a staff member and deemed valid. If a participant fails to submit a video on a medication day or if a submitted video is deemed invalid (i.e., not the correct person or no appropriate ingestion of medication), the participant will not receive the scheduled incentive amount that day and the daily incentive value will be decreased.The participant will have opportunities the next day to again resume adherence. After taking the medication again for one week, participants will earn a reduced incentive until they adhere to the medication schedule for a week.