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Prevention and Treatment of Patient Before, During, and After Covid-19 Infection (AntiCov-220)

Primary Purpose

Covid19

Status
Completed
Phase
Phase 2
Locations
Vietnam
Study Type
Interventional
Intervention
AntiCov-220 (1)
AntiCov-220 (2)
Sponsored by
Nguyen Thi Trieu, MD
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional treatment trial for Covid19 focused on measuring AIDS, HIV, HBV, HCV, Stroke, Metabolic dissorder, Stress

Eligibility Criteria

16 Years - 82 Years (Child, Adult, Older Adult)All SexesAccepts Healthy Volunteers

Inclusion Criteria:

  • All patients with underlying medical conditions who have been taking medications for these conditions.
  • Patients with AIDS, HIV, HBV, HCV, and patients with co-infections.
  • The cancer patients are stable.
  • Patients with congenital or acquired immunodeficiency.

Exclusion Criteria:

  • Unstable cancer patients.

Sites / Locations

  • Saigon Biopharma Company Limited

Arms of the Study

Arm 1

Arm 2

Arm Type

Experimental

Experimental

Arm Label

AIDS, HIV, HBV, HCV, co-infections.

"stable" cancer, acquired or congenital immunodeficiency.

Arm Description

Experimental benefits in resistance to SARS-COV-2 were observed in all patients who had previously received certain components of the AntiCov-220 (1) for various therapeutic purposes.

Experimental benefits in resistance to SARS-COV-2 were observed in all patients who had previously received certain components of the AntiCov-220 (2) for various therapeutic purposes.

Outcomes

Primary Outcome Measures

Assessment on the level of safety and tolerability of patients against the effects of Covid-19.(Arm 1)
COVID-19 is a contagious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Anticov-220 characterized by the targeting and destruction of COVID-19 One case of Covid-19 infection with no severe change in a patient with HBeAg (+). A case of HIV/AIDS turns back to HIV. Of the 35 follow-up subjects in this group, 20 were vaccinated and 15 were not. (The two cases mentioned above have not been vaccinated).

Secondary Outcome Measures

Assessment on the level of safety and tolerability of patients against the effects of Covid-19.(Arm 2)
COVID-19 is a contagious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Anticov-220 characterized by the targeting and destruction of COVID-19 _ No one has been infected with Covid-19. Of the 47 follow-up subjects in this group, 40 were vaccinated and 7 were unvaccinated.

Full Information

First Posted
September 8, 2021
Last Updated
April 26, 2022
Sponsor
Nguyen Thi Trieu, MD
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1. Study Identification

Unique Protocol Identification Number
NCT05043324
Brief Title
Prevention and Treatment of Patient Before, During, and After Covid-19 Infection
Acronym
AntiCov-220
Official Title
Prevention and Treatment of Patient Before, During, and After Covid-19 Infection
Study Type
Interventional

2. Study Status

Record Verification Date
April 2022
Overall Recruitment Status
Completed
Study Start Date
February 20, 2020 (Actual)
Primary Completion Date
April 20, 2022 (Actual)
Study Completion Date
April 27, 2022 (Actual)

3. Sponsor/Collaborators

Responsible Party, by Official Title
Sponsor-Investigator
Name of the Sponsor
Nguyen Thi Trieu, MD

4. Oversight

Studies a U.S. FDA-regulated Drug Product
No
Studies a U.S. FDA-regulated Device Product
No

5. Study Description

Brief Summary
AntiCov-220 prevents and treats before, during, and after infection with SARS-Cov-2. The composition is fractionally extracted from herbs, using flavonoids, isoflavonoids, and pregnenolone in combination with ascorbic acid as the key compounds in preventing and killing SARS-CoV-2; increase antibodies and protect cells; supplementing precursors to help the body strengthen antibodies and reduce the risk of infection; destroy spike protein, toxic protein, help prevent blood clots causing stroke; restore the physiological function of cells after virus infection; helps the body to stabilize the amount of cortisol in the blood as well as stabilize the production of specific antibodies. The composition participates in anti-inflammatory and cells protecting process, bringing blood cortisol, B-lymphocytes, Cyfra 21-1, WBC, CRP, fever, dyspnea, and other signs of respiratory tract inflammation to a normal state and normal limit.
Detailed Description
AntiCov-220 can eliminate COVID-19 and its variants at a very early stage when they have not had enough time to multiply and cause disease. AntiCov-220 contains precursors, flavonoids, special enzymes responsible for protecting human cell membranes and destroying cell membranes of some viruses, especially, COVID-19 cannot replicate in the presence of AntiCov-220 in the body. AntiCov-220 contains precursors of cortisol. As the investigators know, cortisol has a cell anti-inflammatory, blood pressure regulation, blood sugar regulation, energy booster, and anti-stress role. It provides precursors to help direct and balance the amount of cortisol in the body that has been imbalanced before. AntiCov-220 contains flavonoids and Isoflavonoids that are cytoprotective antioxidants, clinically proven to destroy SARS-CoV-2, HBV, HIV, HCV, viruses, reduce complications after COVID-19 infection, prevent neurological sequelae, stroke, cardiovascular sequelae, respiratory sequelae, ... The anti-inflammatory, stress-reducing, cell-protective, anti-viral, and immunosuppressive process are performed by an in vivo method that has proven its effectiveness more than ten years ago. AntiCov-220 is an innovative product that can fight against COVID-19 and its variants in the current epidemic situation. AntiCov-220 is committed to protecting the community of people infected with HBV, HIV, HCV, SARS-CoV-2 against the risk of the COVID-19 pandemic and its mutations. AntiCov-220 easy to implement, highly effective, and helps reduce public health costs, which is essential in protecting human health. AntiCov-220 can be used alongside with current standard treatment regimens prescribed by the World Health Organization.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Covid19
Keywords
AIDS, HIV, HBV, HCV, Stroke, Metabolic dissorder, Stress

7. Study Design

Primary Purpose
Treatment
Study Phase
Phase 2
Interventional Study Model
Parallel Assignment
Masking
Participant
Allocation
Non-Randomized
Enrollment
82 (Actual)

8. Arms, Groups, and Interventions

Arm Title
AIDS, HIV, HBV, HCV, co-infections.
Arm Type
Experimental
Arm Description
Experimental benefits in resistance to SARS-COV-2 were observed in all patients who had previously received certain components of the AntiCov-220 (1) for various therapeutic purposes.
Arm Title
"stable" cancer, acquired or congenital immunodeficiency.
Arm Type
Experimental
Arm Description
Experimental benefits in resistance to SARS-COV-2 were observed in all patients who had previously received certain components of the AntiCov-220 (2) for various therapeutic purposes.
Intervention Type
Drug
Intervention Name(s)
AntiCov-220 (1)
Intervention Description
The daily maintenance, AntiCov-220 (1) dose is to take 3 times a day, 1 tablet each time.
Intervention Type
Drug
Intervention Name(s)
AntiCov-220 (2)
Intervention Description
The daily maintenance, AntiCov-220 (2) dose is to take 3 times a day, 1 tablet each time.
Primary Outcome Measure Information:
Title
Assessment on the level of safety and tolerability of patients against the effects of Covid-19.(Arm 1)
Description
COVID-19 is a contagious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Anticov-220 characterized by the targeting and destruction of COVID-19 One case of Covid-19 infection with no severe change in a patient with HBeAg (+). A case of HIV/AIDS turns back to HIV. Of the 35 follow-up subjects in this group, 20 were vaccinated and 15 were not. (The two cases mentioned above have not been vaccinated).
Time Frame
- 18 months
Secondary Outcome Measure Information:
Title
Assessment on the level of safety and tolerability of patients against the effects of Covid-19.(Arm 2)
Description
COVID-19 is a contagious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Anticov-220 characterized by the targeting and destruction of COVID-19 _ No one has been infected with Covid-19. Of the 47 follow-up subjects in this group, 40 were vaccinated and 7 were unvaccinated.
Time Frame
- 18 months

10. Eligibility

Sex
All
Minimum Age & Unit of Time
16 Years
Maximum Age & Unit of Time
82 Years
Accepts Healthy Volunteers
Accepts Healthy Volunteers
Eligibility Criteria
Inclusion Criteria: All patients with underlying medical conditions who have been taking medications for these conditions. Patients with AIDS, HIV, HBV, HCV, and patients with co-infections. The cancer patients are stable. Patients with congenital or acquired immunodeficiency. Exclusion Criteria: Unstable cancer patients.
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Tran Minh Cam Tu, Dr.
Organizational Affiliation
Saigon Biopharma Company Limited
Official's Role
Principal Investigator
Facility Information:
Facility Name
Saigon Biopharma Company Limited
City
Ho Chi Minh City
ZIP/Postal Code
700000
Country
Vietnam

12. IPD Sharing Statement

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URL
https://www.webmd.com/hiv-aids/aids-hiv-medication
Description
Antiretrovirals: HIV and AIDS Drugs
URL
http://www.webmd.com/a-to-z-guides/what-is-cortisol
Description
Medically Reviewed by Arefa Cassoobhoy, MD, MPH
URL
https://www.webmd.com/diet/foods-high-in-flavonoids
Description
Top Foods High in Flavonoids
URL
https://www.who.int/news-room/fact-sheets/detail/ageing-and-health
Description
Ageing and health
URL
https://pubmed.ncbi.nlm.nih.gov/34100279/
Description
Be aware of SARS-CoV-2 spike protein: There is more than meets the eye

Learn more about this trial

Prevention and Treatment of Patient Before, During, and After Covid-19 Infection

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