Babies in Glasses; a Feasibility Study. (BiG)
Cerebral Visual Impairment, Refractive and Accommodative Disorders, Hypoxic-Ischemic Encephalopathy
About this trial
This is an interventional other trial for Cerebral Visual Impairment focused on measuring Cerebral Visual Impairment, CVI, Visual Processing Disorder, Visual Perceptual Deficits, VPD, Accommodative Disorders, Hypo-accommodation, Accommodative lag, Hypoxic Ischaemic Encephalopathy, Premature Birth, Near Vision Glasses, Spectacle correction, Refractive correction, Refractive Error, Early spectacle correction, Spectacles, Glasses, Perinatal Brain Insult, Brain Injury, Neurodevelopment, Infant, Baby, Functional broadband Near Infrared Spectroscopy, fBNIRS
Eligibility Criteria
Inclusion criteria:
- All term infants undergoing therapeutic hypothermia for hypoxic ischaemic encephalopathy (HIE).
- All preterm infants born at <29 weeks gestational age.
Specifically, all children fulfilling these criteria will be eligible. Evidence of hypo-accommodation is not required.
Exclusion criteria:
- Infants that are still an inpatient at 8 weeks corrected gestational age.
- Ocular exclusion criteria: children with unrelated congenital or developmental ocular abnormality such as cataract requiring surgery, genetic retinal disease, coloboma. Retinopathy of prematurity will not be an exclusion criterion.
- Infants with high refractive error (more than -6.00D spherical equivalent or +8.00D spherical equivalent).
Sites / Locations
- University College London Hospital
Arms of the Study
Arm 1
Arm 2
Arm 3
No Intervention
Experimental
Experimental
A (control)
B1 (intervention)
B2 (intervention)
First visit assessments at 8 weeks corrected gestational age. No glasses prescribed.
First visit assessments at 8 weeks corrected gestational age. Full time spectacle wear prescribed.
First visit assessments at 16 weeks corrected gestational age. Full time spectacle wear prescribed.