Online-Delivered Comprehensive Behavioral Intervention for Tics-Enhanced (CBIT-E)
Persistent Tic Disorders, Tourette Disorder
About this trial
This is an interventional treatment trial for Persistent Tic Disorders focused on measuring Persistent Tic Disorders, Tourette Disorder, Tics, Behavior Therapy, Children
Eligibility Criteria
Inclusion Criteria:
- ages 9-17
- meets Diagnostic and Statistical Manual of Mental Disorders-5 (DSM-5) diagnostic criteria for TD or PTD
- at screening visit, a Parent Tic Questionnaire (PTQ) total score > 18 and < 60 OR > 12 and < 40 if persistent tic disorder (for total scores > 60 on the PTQ, the research team will examine the patient's global functioning to determine participation appropriateness. The research team will consider if other treatments, such as medication, may be more appropriate for participants with PTQ total scores > 60. If the participant is already taking tic medication, or tic medication has been unsuccessful in the past, then he/she may be considered for the study)
- at baseline visit, a Yale Global Tic Severity Score (YGTSS Total Score) > 14 and < 30 OR > 10 and < 20 if persistent tic disorder (for total scores > 30 on the YGTSS, the research team will examine the patient's global functioning to determine participation appropriateness)
- no history of behavioral treatment for tics, including self-guided therapy programs for tics
- unmedicated or on stable medication for tics and other psychiatric disorder for at least 6 weeks, with no planned changes during study participation
- access to a personal computer (desktop or laptop) with a camera
- access to an Internet connection with a minimum speed of 5 megabytes per second (Mbps)
- fluent English speaker.
Exclusion Criteria:
- co-occurring disorders that require more immediate treatment or change to current treatment
- T-Score < 37 on the Wechsler Abbreviated Scale of Intelligence (WASI) - Vocabulary subtest
- T-Score > 70 on the inattention or hyperactivity/impulsivity scales of the Conners 3-Parent Short (C 3-PS).
Sites / Locations
- Marquette UniversityRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
No Intervention
CBIT-E
Waitlist Control (WLC)
For those randomized to CBIT-E, treatment will be administered according to the standard CBIT manual, which includes psychoeducation, functional assessment/interventions, habit reversal training, relaxation techniques, and a motivational reward program. However, there will be two modifications. CBIT-E will include additional in-session and out of session practice of exercises, called competing response. Treatment will include a screening visit, baseline assessment, 11 weeks (9 sessions) of CBIT-E, a post treatment assessment, and a three-month follow up assessment. Further, starting after session 3, there will be four 15-minute practice periods scheduled each week between sessions. During these practice periods, the child and therapist will meet over Microsoft Teams and the therapist will administer an enhanced reward task.
These participants will not receive treatment during the 11-week period. Instead, they will be placed on a waitlist to receive standard CBIT following the end of the study period. The final assessment will be approximately 11 weeks after baseline.