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A Study of Olezarsen (ISIS 678354) Administered to Participants With Severe Hypertriglyceridemia

Primary Purpose

Severe Hypertriglyceridemia

Status
Recruiting
Phase
Phase 3
Locations
International
Study Type
Interventional
Intervention
Olezarsen
Placebo
Sponsored by
Ionis Pharmaceuticals, Inc.
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional treatment trial for Severe Hypertriglyceridemia focused on measuring ISIS 678354, Fasting Triglycerides, Apolipoprotein C-III, Very Low-Density Lipoprotein Cholesterol, High-Density Lipoprotein-Cholesterol, Non-High-Density Lipoprotein-Cholesterol, Olezarsen

Eligibility Criteria

18 Years - undefined (Adult, Older Adult)All SexesDoes not accept healthy volunteers

Key Inclusion Criteria:

  • Fasting TG ≥ 500 mg/dL (5.65 mmol/L) at Screening and Qualification
  • Patients must be on lipid-lowering therapy that should adhere to standard of care (SOC) per local guidelines. Lipid-lowering medications should be optimized and stabilized for at least 4 weeks prior to Screening to minimize changes in these medications during the study.

Key Exclusion Criteria:

  • Hemoglobin A1c (HbA1c) ≥ 9.5% at Screening
  • Alanine aminotransferase or aspartate aminotransferase > 3.0 × upper limit of normal
  • Total bilirubin > upper limit of normal unless due to Gilbert's syndrome
  • Estimated GFR < 30 mL/min/1.73 m^2

Sites / Locations

  • Accel Research Sites NetworkRecruiting
  • Mayo ClinicRecruiting
  • Velocity Clinical ResearchRecruiting
  • Diabetes/Lipid Management & Research CenterRecruiting
  • University of California, San Diego (UCSD)Recruiting
  • LA Universal Research Center, Inc.Recruiting
  • America Clinical TrialsRecruiting
  • Excel Medical Clinical Trials, LLCRecruiting
  • Southeast Clinical Research LLCRecruiting
  • Westside Center for Clinical ResearchRecruiting
  • Finlay Medical ResearchRecruiting
  • Innovia Research Center, INCRecruiting
  • Ocala Cardiovascular ResearchRecruiting
  • IMA Clinical ResearchRecruiting
  • VICIS Clinical ResearchRecruiting
  • Bayside Clinical ResearchRecruiting
  • IACT HealthRecruiting
  • IMA Clinical Research ChicagoRecruiting
  • Affinity HealthRecruiting
  • West Broadway ClinicRecruiting
  • Kansas University Medical CenterRecruiting
  • Clinical Trials of America, LLCRecruiting
  • Continental Clinical SolutionsRecruiting
  • University of Michigan Hospital and Health Systems/ Dept. of Pharmacy-Research PharmacyRecruiting
  • Aa Mrc, LlcRecruiting
  • Washington University School of MedicineRecruiting
  • IMA Clinical ResearchRecruiting
  • Bryan Medical Center Clinical ResearchRecruiting
  • Palm Research Center, INC.Recruiting
  • Hudson County Clinical Trials Research CenterRecruiting
  • Modern MedicineRecruiting
  • Northwell HealthRecruiting
  • NYU LangoneRecruiting
  • Columbia UniversityRecruiting
  • Circuit ClinicalRecruiting
  • Modern MedicalRecruiting
  • Novant Health Cancer Institute Elizabeth Investigational Drug ServicesRecruiting
  • Cone Medical CenterRecruiting
  • Clinical Trials of America, LLCRecruiting
  • Wake Forest University Health SciencesRecruiting
  • Aventiv ResearchRecruiting
  • Summit Research Group, LLCRecruiting
  • Hightower Clinical Trial ServicesRecruiting
  • Velocity Clinical ResearchRecruiting
  • The Miriam HospitalRecruiting
  • Health ConceptsRecruiting
  • Chattanooga Research & Medicine, PLLCRecruiting
  • Velocity Clinical ResearchRecruiting
  • University of Texas SouthwesternRecruiting
  • Baylor College of MedicineRecruiting
  • Medicus Alliance Clinical ResearchRecruiting
  • Velocity ClinicalRecruiting
  • Manassas Clinical Research CenterRecruiting
  • York Clinical Research LLCRecruiting
  • West Virginia University Heart and Vascular InstituteRecruiting
  • Royal Prince Alfred HospitalRecruiting
  • Royal North Shoe HospitalRecruiting
  • Dr. Heart Pty Ltd at Cholesterol Care AustraliaRecruiting
  • Monash Medical CentreRecruiting
  • The Alfred HospitalRecruiting
  • Royal Adelaide HospitalRecruiting
  • MHAT Blagoevgrad ADRecruiting
  • Medical Center Doctor Staykov EOODRecruiting
  • Medical Center Diamedical 2013 OODRecruiting
  • MHAT "Dr. Tota Venkova" ADRecruiting
  • Medical Center "Hera" EOODRecruiting
  • SHAT "Special Medic" LtdRecruiting
  • Medical Center Rusemed EOODRecruiting
  • DCC 1 SlivenRecruiting
  • Gabriela ZhelyazkovaRecruiting
  • Medical Center Smolyan Clinical Research OODRecruiting
  • Medical Center Endomedical EOODRecruiting
  • Medical Centar "KALIMAT"Recruiting
  • MC Doctor Kalchev OODRecruiting
  • UMHAT Sofiamed OODRecruiting
  • New Rehabilitation CenterRecruiting
  • UMHAT Prof. Dr. Stoyan Kirkovich AD, Clinic of CardiologyRecruiting
  • Medical Centre Nevromedics EOODRecruiting
  • Arc BiosystemsRecruiting
  • Canadian Phase Onward IncRecruiting
  • Ecogene-21Recruiting
  • Institut de recherches cliniques de Montréal (IRCM)Recruiting
  • Clinique des Maladies Lipidiques de Quebec Inc.Recruiting
  • MEDICUS SERVICES s.r.o.Recruiting
  • EDUMED s.r.o.Recruiting
  • Fakultní nemocnice Hradec KrálovéRecruiting
  • EDUMED s.r.o.Recruiting
  • Fakultni nemocnice OstravaRecruiting
  • Vseobecna fakultni nemocniceRecruiting
  • Lekarna Poliklinika HurkaRecruiting
  • Interni AmbulanceRecruiting
  • Aalborg University HospitalRecruiting
  • Aarhus University HospitalRecruiting
  • Esbjerg HospitalRecruiting
  • Bispebjerg HospitalRecruiting
  • Herlev HospitalRecruiting
  • Godstrup Regional HospitalRecruiting
  • Regionshospitalet ViborgRecruiting
  • Turku University HospitalRecruiting
  • Ylitornio Health Care CenterRecruiting
  • Hôpital Louis PradelRecruiting
  • CHU Dijon BourgogneRecruiting
  • Hopital de la ConceptionRecruiting
  • CHU Montpellier - Hôpital LapeyronieRecruiting
  • Hopital Pitie Salpetriere APHPRecruiting
  • CHU Nantes - Hopital Nord LaennecRecruiting
  • Stoffwechselcentrum Charite Campus VirchowRecruiting
  • Universitaetsklinikum Carl Gustav Carus an der TU DresdenRecruiting
  • St. Josefskrankenhaus,Recruiting
  • Uniklinik KölnRecruiting
  • Praxis Dr. med. TaggeselleRecruiting
  • BKS Research KftRecruiting
  • Medifarma 98 KftRecruiting
  • CRU Hungary KftRecruiting
  • Semmelweis Egyetem Kardiológiai RehabilitacioRecruiting
  • Belinus BTRecruiting
  • Debreceni Egyetem Klinikai Kozpont Belgyogyaszat A epuletRecruiting
  • IPR Hungary Kft.Recruiting
  • Borbanya Praxis Eü KFTRecruiting
  • Fejer Megyei Szent Gyorgy Egyetemi Oktato KorhazRecruiting
  • DRC Gyogyszervizsgalo Kozpont KftRecruiting
  • SOROKA Medical CenterRecruiting
  • Lady Davis Carmel Medical CenterRecruiting
  • Shaare Zedek Medical CenterRecruiting
  • Hadassah Hebrew University Ein Kerm MCRecruiting
  • Rabin Medical CenterRecruiting
  • Kaplan Medical CenterRecruiting
  • Sheba Medical CenterRecruiting
  • IRCCS Azienda Ospedaliero Universitaria di Bologna Policlinico di SantOrsolaRecruiting
  • Ospdale E. BassiniRecruiting
  • ASST Grande Ospedale Metropolitano NiguardaRecruiting
  • Azienda Ospedaliera Universitaria Federico IIRecruiting
  • A.O. Policlinico Universitario P. GiacconeRecruiting
  • Policlinico UmbertoRecruiting
  • Fondazione Policlinico Universitario A. Gemelli IRCCS - Universita Cattolica del Sacro CuoreRecruiting
  • Academic Medical Center - Department of Vascular MedicineRecruiting
  • Rijnstate ArnhemRecruiting
  • Albert Schweitzer ziekenhuisRecruiting
  • Ziekenhuis Gelderse ValleiRecruiting
  • Radboud UMCRecruiting
  • Erasmus MCRecruiting
  • Universitair Medisch Centrum UtrechtRecruiting
  • Auckland City HospitalRecruiting
  • New Zealand Clinical ResearchRecruiting
  • Wellington Regional HospitalRecruiting
  • Lipid ClinicRecruiting
  • SalviaRecruiting
  • Praktyka Lekarska Ewa KrzyzagorskaRecruiting
  • ClinMedica Research Sp.z o.o.Recruiting
  • Futuremeds sp. z o.oRecruiting
  • Instytut Centrum Zdrowia Matki Polki KlinikaRecruiting
  • Centro Hospitalar do Baixo Vouga Hospital Infante D. PedroRecruiting
  • Centro Hospitalar e Universitário de Coimbra, EPERecruiting
  • Hospital Egas Moniz - Centro Hospitalar de Lisboa OcidentalRecruiting
  • Centro Hospitalar Universitário de São João Consultas Externas de Endocrinologia K13Recruiting
  • Centro HospitalarRecruiting
  • Nemocnica s poliklinikou BreznoRecruiting
  • Vychodoslovensky Ustav srdcovych a cievnych chorob a.s.Recruiting
  • Human-Care s.r.o.Recruiting
  • Cardio D&RRecruiting
  • Iatros InternationalRecruiting
  • Unitas HospitalRecruiting
  • Dr Jan Engelbrecht and Ass. IncRecruiting
  • TREAD Research - Department of CardiologyRecruiting
  • University of Cape town - Lipid FactoryRecruiting
  • Chatsmed Garden HospitalRecruiting
  • Hospital Abente y LagoRecruiting
  • Hospital de la Santa Creu i de Sant PauRecruiting
  • Hospital Clinic BarcelonaRecruiting
  • Institut d'Investigació i Innovació Parc Taulí (I3PT) Departament Medicina UniversitatRecruiting
  • Hospital Universitari de BellvitgeRecruiting
  • Hospital Universitario Reina SofiaRecruiting
  • Hospital UniversitarioRecruiting
  • Hospital Virgen del Rocio Edificio Centro de Diagnostico y Tratamiento (CDT)Recruiting
  • Hospital Universitari Sant Joan de Reus.Recruiting
  • Sahlgrenska, University HospitalRecruiting
  • Karolinska University Hospital HuddingeRecruiting
  • Hacettepe University Medical FacultyRecruiting
  • Kocaeli University Faculty of MedicineRecruiting
  • Necmettin Erbakan University Meram Medical FacultyRecruiting
  • Oak Tree Surgery and Pensilva Health CentreRecruiting
  • Newquay Health CentreRecruiting
  • Panthera BiopartnersRecruiting
  • Panthera BiopartnersRecruiting
  • Huddersfield Royal InfirmaryRecruiting
  • Sandwell General HospitalRecruiting
  • Waterloo Medical CentreRecruiting
  • PantheraRecruiting
  • Hull Royal InfirmaryRecruiting
  • PantheraRecruiting
  • PantheraRecruiting

Arms of the Study

Arm 1

Arm 2

Arm Type

Experimental

Placebo Comparator

Arm Label

Olezarsen

Placebo

Arm Description

Olezarsen will be administered once every 4 weeks by subcutaneous (SC) injection from Week 1 through Week 49.

Olezarsen-matching placebo will be administered once every 4 weeks by SC injection from Week 1 through Week 49.

Outcomes

Primary Outcome Measures

Percent Change from Baseline in Fasting TG at 6 Months (Average of Weeks 25 and 27) Compared to Placebo

Secondary Outcome Measures

Percent Change from Baseline in Fasting TG at 12 Months (Average of Weeks 51 and 53) Compared to Placebo
Proportion of Participants Who Achieve Fasting TG Less Than (<) 500 milligrams per deciliter (mg/dL) (5.7 millimoles per liter [mmol/L]) at 6 and 12 Months Compared to Placebo
Proportion of Participants Who Achieve Fasting TG < 880 mg/dL (10 mmol/L) at 6 and 12 Months Compared to Placebo in the Subgroup of Participants with Baseline TG ≥ 880 mg/dL
Proportion of Participants Who Achieve Fasting TG < 1000 mg/dL (11.29 mmol/L) at 6 and 12 Months Compared to Placebo in the Subgroup of Participants with Baseline TG ≥ 1000 mg/dL
Percent Change from Baseline in Fasting Apolipoprotein C-III (ApoC-III) at 6 and 12 Months Compared to Placebo
Percent Change from Baseline in Fasting Very Low-Density Lipoprotein Cholesterol (VLDL-C) at 6 and 12 Months Compared to Placebo
Percent Change from Baseline in Fasting Non-High-Density Lipoprotein-Cholesterol (Non-HDL-C) at 6 and 12 Months Compared to Placebo
Percent Change from Baseline in Fasting High-Density Lipoprotein-Cholesterol (HDL-C) at 6 and 12 Months Compared to Placebo
Adjudicated Acute Pancreatitis Event Rate During the Treatment Period Compared to Placebo, in Participants with ≥ 2 Events of Adjudicated Acute Pancreatitis in 5 Years Prior to Enrollment
Adjudicated Acute Pancreatitis Event Rate from Week 13 to Week 53 Compared to Placebo in Participants with ≥ 2 Events of Adjudicated Acute Pancreatitis in 5 Years Prior to Enrollment
Adjudicated Acute Pancreatitis Event Rate During the Treatment Period Compared to Placebo
Adjudicated Acute Pancreatitis Event Rate from Week 13 to Week 53 Compared to Placebo

Full Information

First Posted
October 4, 2021
Last Updated
October 18, 2023
Sponsor
Ionis Pharmaceuticals, Inc.
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1. Study Identification

Unique Protocol Identification Number
NCT05079919
Brief Title
A Study of Olezarsen (ISIS 678354) Administered to Participants With Severe Hypertriglyceridemia
Official Title
A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study of ISIS 678354 Administered Subcutaneously to Patients With Severe Hypertriglyceridemia
Study Type
Interventional

2. Study Status

Record Verification Date
October 2023
Overall Recruitment Status
Recruiting
Study Start Date
October 25, 2021 (Actual)
Primary Completion Date
October 2024 (Anticipated)
Study Completion Date
February 2025 (Anticipated)

3. Sponsor/Collaborators

Responsible Party, by Official Title
Sponsor
Name of the Sponsor
Ionis Pharmaceuticals, Inc.

4. Oversight

Studies a U.S. FDA-regulated Drug Product
Yes
Studies a U.S. FDA-regulated Device Product
No
Data Monitoring Committee
No

5. Study Description

Brief Summary
The purpose of the study is to evaluate the efficacy of olezarsen as compared to placebo on the percent change in fasting triglycerides (TG) from baseline.
Detailed Description
This is a multi-center, randomized, double-blind, placebo-controlled study in up to approximately 540 participants. Participants will be randomized to receive olezarsen or placebo in a 53-week treatment period. The length of participation in the study will be approximately 78 weeks, which includes an up to 12-week screening period, a 53-week treatment period, and a 13-week post-treatment evaluation period or transition to open-label extension (OLE) study with up to 1-year treatment. The Screening Period was extended with no impact to overall study timelines. Endpoints added to provide assessment on the pancreatitis rate after olezarsen reaches steady state levels.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Severe Hypertriglyceridemia
Keywords
ISIS 678354, Fasting Triglycerides, Apolipoprotein C-III, Very Low-Density Lipoprotein Cholesterol, High-Density Lipoprotein-Cholesterol, Non-High-Density Lipoprotein-Cholesterol, Olezarsen

7. Study Design

Primary Purpose
Treatment
Study Phase
Phase 3
Interventional Study Model
Parallel Assignment
Masking
ParticipantCare ProviderInvestigator
Allocation
Randomized
Enrollment
540 (Anticipated)

8. Arms, Groups, and Interventions

Arm Title
Olezarsen
Arm Type
Experimental
Arm Description
Olezarsen will be administered once every 4 weeks by subcutaneous (SC) injection from Week 1 through Week 49.
Arm Title
Placebo
Arm Type
Placebo Comparator
Arm Description
Olezarsen-matching placebo will be administered once every 4 weeks by SC injection from Week 1 through Week 49.
Intervention Type
Drug
Intervention Name(s)
Olezarsen
Other Intervention Name(s)
AKCEA-APOCIII-LRx, ISIS 678354
Intervention Description
Olezarsen will be administered by SC injection.
Intervention Type
Drug
Intervention Name(s)
Placebo
Intervention Description
Olezarsen-matching placebo will be administered by SC injection.
Primary Outcome Measure Information:
Title
Percent Change from Baseline in Fasting TG at 6 Months (Average of Weeks 25 and 27) Compared to Placebo
Time Frame
Baseline and Month 6
Secondary Outcome Measure Information:
Title
Percent Change from Baseline in Fasting TG at 12 Months (Average of Weeks 51 and 53) Compared to Placebo
Time Frame
Baseline and Month 12
Title
Proportion of Participants Who Achieve Fasting TG Less Than (<) 500 milligrams per deciliter (mg/dL) (5.7 millimoles per liter [mmol/L]) at 6 and 12 Months Compared to Placebo
Time Frame
Month 6 and 12
Title
Proportion of Participants Who Achieve Fasting TG < 880 mg/dL (10 mmol/L) at 6 and 12 Months Compared to Placebo in the Subgroup of Participants with Baseline TG ≥ 880 mg/dL
Time Frame
Month 6 and 12
Title
Proportion of Participants Who Achieve Fasting TG < 1000 mg/dL (11.29 mmol/L) at 6 and 12 Months Compared to Placebo in the Subgroup of Participants with Baseline TG ≥ 1000 mg/dL
Time Frame
Month 6 and Month 12
Title
Percent Change from Baseline in Fasting Apolipoprotein C-III (ApoC-III) at 6 and 12 Months Compared to Placebo
Time Frame
Baseline, Month 6 and 12
Title
Percent Change from Baseline in Fasting Very Low-Density Lipoprotein Cholesterol (VLDL-C) at 6 and 12 Months Compared to Placebo
Time Frame
Baseline, Month 6 and 12
Title
Percent Change from Baseline in Fasting Non-High-Density Lipoprotein-Cholesterol (Non-HDL-C) at 6 and 12 Months Compared to Placebo
Time Frame
Baseline, Month 6 and 12
Title
Percent Change from Baseline in Fasting High-Density Lipoprotein-Cholesterol (HDL-C) at 6 and 12 Months Compared to Placebo
Time Frame
Baseline, Month 6 and 12
Title
Adjudicated Acute Pancreatitis Event Rate During the Treatment Period Compared to Placebo, in Participants with ≥ 2 Events of Adjudicated Acute Pancreatitis in 5 Years Prior to Enrollment
Time Frame
Week 1 through Week 53
Title
Adjudicated Acute Pancreatitis Event Rate from Week 13 to Week 53 Compared to Placebo in Participants with ≥ 2 Events of Adjudicated Acute Pancreatitis in 5 Years Prior to Enrollment
Time Frame
Week 13 through Week 53
Title
Adjudicated Acute Pancreatitis Event Rate During the Treatment Period Compared to Placebo
Time Frame
Week 1 through Week 53
Title
Adjudicated Acute Pancreatitis Event Rate from Week 13 to Week 53 Compared to Placebo
Time Frame
Week 13 through Week 53

10. Eligibility

Sex
All
Minimum Age & Unit of Time
18 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Key Inclusion Criteria: Fasting TG ≥ 500 mg/dL (5.65 mmol/L) at Screening and Qualification Patients must be on lipid-lowering therapy that should adhere to standard of care (SOC) per local guidelines. Lipid-lowering medications should be optimized and stabilized for at least 4 weeks prior to Screening to minimize changes in these medications during the study. Key Exclusion Criteria: Hemoglobin A1c (HbA1c) ≥ 9.5% at Screening Alanine aminotransferase or aspartate aminotransferase > 3.0 × upper limit of normal Total bilirubin > upper limit of normal unless due to Gilbert's syndrome Estimated GFR < 30 mL/min/1.73 m^2
Central Contact Person:
First Name & Middle Initial & Last Name or Official Title & Degree
Ionis Pharmaceuticals
Phone
(844) 980-5110
Email
ionisNCT05079919study@clinicaltrialmedia.com
Facility Information:
Facility Name
Accel Research Sites Network
City
Birmingham
State/Province
Alabama
ZIP/Postal Code
35216
Country
United States
Individual Site Status
Recruiting
Facility Name
Mayo Clinic
City
Scottsdale
State/Province
Arizona
ZIP/Postal Code
85259
Country
United States
Individual Site Status
Recruiting
Facility Name
Velocity Clinical Research
City
Chula Vista
State/Province
California
ZIP/Postal Code
91911
Country
United States
Individual Site Status
Recruiting
Facility Name
Diabetes/Lipid Management & Research Center
City
Huntington Beach
State/Province
California
ZIP/Postal Code
92648
Country
United States
Individual Site Status
Recruiting
Facility Name
University of California, San Diego (UCSD)
City
La Jolla
State/Province
California
ZIP/Postal Code
92037
Country
United States
Individual Site Status
Recruiting
Facility Name
LA Universal Research Center, Inc.
City
Los Angeles
State/Province
California
ZIP/Postal Code
90057
Country
United States
Individual Site Status
Recruiting
Facility Name
America Clinical Trials
City
Tarzana
State/Province
California
ZIP/Postal Code
91356
Country
United States
Individual Site Status
Recruiting
Facility Name
Excel Medical Clinical Trials, LLC
City
Boca Raton
State/Province
Florida
ZIP/Postal Code
33434
Country
United States
Individual Site Status
Recruiting
Facility Name
Southeast Clinical Research LLC
City
Chiefland
State/Province
Florida
ZIP/Postal Code
32626
Country
United States
Individual Site Status
Recruiting
Facility Name
Westside Center for Clinical Research
City
Jacksonville
State/Province
Florida
ZIP/Postal Code
32205
Country
United States
Individual Site Status
Recruiting
Facility Name
Finlay Medical Research
City
Miami
State/Province
Florida
ZIP/Postal Code
33126
Country
United States
Individual Site Status
Recruiting
Facility Name
Innovia Research Center, INC
City
Miramar
State/Province
Florida
ZIP/Postal Code
33027
Country
United States
Individual Site Status
Recruiting
Facility Name
Ocala Cardiovascular Research
City
Ocala
State/Province
Florida
ZIP/Postal Code
34471
Country
United States
Individual Site Status
Recruiting
Facility Name
IMA Clinical Research
City
Saint Petersburg
State/Province
Florida
ZIP/Postal Code
33709
Country
United States
Individual Site Status
Recruiting
Facility Name
VICIS Clinical Research
City
Tampa
State/Province
Florida
ZIP/Postal Code
33614
Country
United States
Individual Site Status
Recruiting
Facility Name
Bayside Clinical Research
City
Trinity
State/Province
Florida
ZIP/Postal Code
34655
Country
United States
Individual Site Status
Recruiting
Facility Name
IACT Health
City
Columbus
State/Province
Georgia
ZIP/Postal Code
31904
Country
United States
Individual Site Status
Recruiting
Facility Name
IMA Clinical Research Chicago
City
Chicago
State/Province
Illinois
ZIP/Postal Code
60602
Country
United States
Individual Site Status
Recruiting
Facility Name
Affinity Health
City
Oak Brook
State/Province
Illinois
ZIP/Postal Code
60523
Country
United States
Individual Site Status
Recruiting
Facility Name
West Broadway Clinic
City
Council Bluffs
State/Province
Iowa
ZIP/Postal Code
51501
Country
United States
Individual Site Status
Recruiting
Facility Name
Kansas University Medical Center
City
Kansas City
State/Province
Kansas
ZIP/Postal Code
66160
Country
United States
Individual Site Status
Recruiting
Facility Name
Clinical Trials of America, LLC
City
Monroe
State/Province
Louisiana
ZIP/Postal Code
71201
Country
United States
Individual Site Status
Recruiting
Facility Name
Continental Clinical Solutions
City
Towson
State/Province
Maryland
ZIP/Postal Code
21204
Country
United States
Individual Site Status
Recruiting
Facility Name
University of Michigan Hospital and Health Systems/ Dept. of Pharmacy-Research Pharmacy
City
Ann Arbor
State/Province
Michigan
ZIP/Postal Code
48109
Country
United States
Individual Site Status
Recruiting
Facility Name
Aa Mrc, Llc
City
Flint
State/Province
Michigan
ZIP/Postal Code
48504
Country
United States
Individual Site Status
Recruiting
Facility Name
Washington University School of Medicine
City
Saint Louis
State/Province
Missouri
ZIP/Postal Code
63110
Country
United States
Individual Site Status
Recruiting
Facility Name
IMA Clinical Research
City
Saint Louis
State/Province
Missouri
ZIP/Postal Code
63117
Country
United States
Individual Site Status
Recruiting
Facility Name
Bryan Medical Center Clinical Research
City
Lincoln
State/Province
Nebraska
ZIP/Postal Code
68506
Country
United States
Individual Site Status
Recruiting
Facility Name
Palm Research Center, INC.
City
Las Vegas
State/Province
Nevada
ZIP/Postal Code
89148
Country
United States
Individual Site Status
Recruiting
Facility Name
Hudson County Clinical Trials Research Center
City
Union City
State/Province
New Jersey
ZIP/Postal Code
07087
Country
United States
Individual Site Status
Recruiting
Facility Name
Modern Medicine
City
Brooklyn
State/Province
New York
ZIP/Postal Code
11235
Country
United States
Individual Site Status
Recruiting
Facility Name
Northwell Health
City
Great Neck
State/Province
New York
ZIP/Postal Code
11021
Country
United States
Individual Site Status
Recruiting
Facility Name
NYU Langone
City
New York
State/Province
New York
ZIP/Postal Code
10016
Country
United States
Individual Site Status
Recruiting
Facility Name
Columbia University
City
New York
State/Province
New York
ZIP/Postal Code
10032
Country
United States
Individual Site Status
Recruiting
Facility Name
Circuit Clinical
City
Niagara Falls
State/Province
New York
ZIP/Postal Code
14304
Country
United States
Individual Site Status
Recruiting
Facility Name
Modern Medical
City
Syosset
State/Province
New York
ZIP/Postal Code
11791
Country
United States
Individual Site Status
Recruiting
Facility Name
Novant Health Cancer Institute Elizabeth Investigational Drug Services
City
Charlotte
State/Province
North Carolina
ZIP/Postal Code
28204
Country
United States
Individual Site Status
Recruiting
Facility Name
Cone Medical Center
City
Greensboro
State/Province
North Carolina
ZIP/Postal Code
27401
Country
United States
Individual Site Status
Recruiting
Facility Name
Clinical Trials of America, LLC
City
Mount Airy
State/Province
North Carolina
ZIP/Postal Code
27030
Country
United States
Individual Site Status
Recruiting
Facility Name
Wake Forest University Health Sciences
City
Salem
State/Province
North Carolina
ZIP/Postal Code
27157
Country
United States
Individual Site Status
Recruiting
Facility Name
Aventiv Research
City
Columbus
State/Province
Ohio
ZIP/Postal Code
43213
Country
United States
Individual Site Status
Recruiting
Facility Name
Summit Research Group, LLC
City
Munroe Falls
State/Province
Ohio
ZIP/Postal Code
44262
Country
United States
Individual Site Status
Recruiting
Facility Name
Hightower Clinical Trial Services
City
Oklahoma City
State/Province
Oklahoma
ZIP/Postal Code
73102
Country
United States
Individual Site Status
Recruiting
Facility Name
Velocity Clinical Research
City
Medford
State/Province
Oregon
ZIP/Postal Code
97504
Country
United States
Individual Site Status
Recruiting
Facility Name
The Miriam Hospital
City
Providence
State/Province
Rhode Island
ZIP/Postal Code
02906
Country
United States
Individual Site Status
Recruiting
Facility Name
Health Concepts
City
Rapid City
State/Province
South Dakota
ZIP/Postal Code
57702
Country
United States
Individual Site Status
Recruiting
Facility Name
Chattanooga Research & Medicine, PLLC
City
Chattanooga
State/Province
Tennessee
ZIP/Postal Code
37404
Country
United States
Individual Site Status
Recruiting
Facility Name
Velocity Clinical Research
City
Cedar Park
State/Province
Texas
ZIP/Postal Code
78613
Country
United States
Individual Site Status
Recruiting
Facility Name
University of Texas Southwestern
City
Dallas
State/Province
Texas
ZIP/Postal Code
75390
Country
United States
Individual Site Status
Recruiting
Facility Name
Baylor College of Medicine
City
Houston
State/Province
Texas
ZIP/Postal Code
77030
Country
United States
Individual Site Status
Recruiting
Facility Name
Medicus Alliance Clinical Research
City
Sugar Land
State/Province
Texas
ZIP/Postal Code
77478
Country
United States
Individual Site Status
Recruiting
Facility Name
Velocity Clinical
City
West Jordan
State/Province
Utah
ZIP/Postal Code
84088
Country
United States
Individual Site Status
Recruiting
Facility Name
Manassas Clinical Research Center
City
Manassas
State/Province
Virginia
ZIP/Postal Code
20110
Country
United States
Individual Site Status
Recruiting
Facility Name
York Clinical Research LLC
City
Norfolk
State/Province
Virginia
ZIP/Postal Code
23510
Country
United States
Individual Site Status
Recruiting
Facility Name
West Virginia University Heart and Vascular Institute
City
Morgantown
State/Province
West Virginia
ZIP/Postal Code
26506
Country
United States
Individual Site Status
Recruiting
Facility Name
Royal Prince Alfred Hospital
City
Camperdown
State/Province
New South Wales
ZIP/Postal Code
2050
Country
Australia
Individual Site Status
Recruiting
Facility Name
Royal North Shoe Hospital
City
Saint Leonards
State/Province
New South Wales
ZIP/Postal Code
2065
Country
Australia
Individual Site Status
Recruiting
Facility Name
Dr. Heart Pty Ltd at Cholesterol Care Australia
City
Woolloongabba
State/Province
Queensland
ZIP/Postal Code
4102
Country
Australia
Individual Site Status
Recruiting
Facility Name
Monash Medical Centre
City
Clayton S.
State/Province
Victoria
ZIP/Postal Code
3168
Country
Australia
Individual Site Status
Recruiting
Facility Name
The Alfred Hospital
City
Melbourne
State/Province
Victoria
ZIP/Postal Code
3004
Country
Australia
Individual Site Status
Recruiting
Facility Name
Royal Adelaide Hospital
City
Adelaide
ZIP/Postal Code
5000
Country
Australia
Individual Site Status
Recruiting
Facility Name
MHAT Blagoevgrad AD
City
Blagoevgrad
ZIP/Postal Code
2700
Country
Bulgaria
Individual Site Status
Recruiting
Facility Name
Medical Center Doctor Staykov EOOD
City
Burgas
ZIP/Postal Code
8008
Country
Bulgaria
Individual Site Status
Recruiting
Facility Name
Medical Center Diamedical 2013 OOD
City
Dimitrovgrad
ZIP/Postal Code
6400
Country
Bulgaria
Individual Site Status
Recruiting
Facility Name
MHAT "Dr. Tota Venkova" AD
City
Gabrovo
ZIP/Postal Code
5300
Country
Bulgaria
Individual Site Status
Recruiting
Facility Name
Medical Center "Hera" EOOD
City
Montana
ZIP/Postal Code
3400
Country
Bulgaria
Individual Site Status
Recruiting
Facility Name
SHAT "Special Medic" Ltd
City
Plovdiv
ZIP/Postal Code
4000
Country
Bulgaria
Individual Site Status
Recruiting
Facility Name
Medical Center Rusemed EOOD
City
Ruse
ZIP/Postal Code
7000
Country
Bulgaria
Individual Site Status
Recruiting
Facility Name
DCC 1 Sliven
City
Sliven
ZIP/Postal Code
8800
Country
Bulgaria
Individual Site Status
Recruiting
Facility Name
Gabriela Zhelyazkova
City
Sliven
ZIP/Postal Code
8800
Country
Bulgaria
Individual Site Status
Recruiting
Facility Name
Medical Center Smolyan Clinical Research OOD
City
Smolyan
ZIP/Postal Code
4700
Country
Bulgaria
Individual Site Status
Recruiting
Facility Name
Medical Center Endomedical EOOD
City
Sofia
ZIP/Postal Code
1606
Country
Bulgaria
Individual Site Status
Recruiting
Facility Name
Medical Centar "KALIMAT"
City
Sofia
ZIP/Postal Code
1680
Country
Bulgaria
Individual Site Status
Recruiting
Facility Name
MC Doctor Kalchev OOD
City
Sofia
ZIP/Postal Code
1700
Country
Bulgaria
Individual Site Status
Recruiting
Facility Name
UMHAT Sofiamed OOD
City
Sofia
ZIP/Postal Code
1797
Country
Bulgaria
Individual Site Status
Recruiting
Facility Name
New Rehabilitation Center
City
Stara Zagora
ZIP/Postal Code
6000
Country
Bulgaria
Individual Site Status
Recruiting
Facility Name
UMHAT Prof. Dr. Stoyan Kirkovich AD, Clinic of Cardiology
City
Stara Zagora
ZIP/Postal Code
6000
Country
Bulgaria
Individual Site Status
Recruiting
Facility Name
Medical Centre Nevromedics EOOD
City
Veliko Tarnovo
ZIP/Postal Code
5006
Country
Bulgaria
Individual Site Status
Recruiting
Facility Name
Arc Biosystems
City
Vancouver
State/Province
British Columbia
ZIP/Postal Code
V6Z 2C7
Country
Canada
Individual Site Status
Recruiting
Facility Name
Canadian Phase Onward Inc
City
Toronto
State/Province
Ontario
ZIP/Postal Code
M3J 0K2
Country
Canada
Individual Site Status
Recruiting
Facility Name
Ecogene-21
City
Chicoutimi
State/Province
Quebec
ZIP/Postal Code
G7H 7K9
Country
Canada
Individual Site Status
Recruiting
Facility Name
Institut de recherches cliniques de Montréal (IRCM)
City
Montréal
State/Province
Quebec
ZIP/Postal Code
H2W 1R7
Country
Canada
Individual Site Status
Recruiting
Facility Name
Clinique des Maladies Lipidiques de Quebec Inc.
City
Québec
State/Province
Quebec
ZIP/Postal Code
G1V 4W2
Country
Canada
Individual Site Status
Recruiting
Facility Name
MEDICUS SERVICES s.r.o.
City
Brandýs Nad Labem
ZIP/Postal Code
250 01
Country
Czechia
Individual Site Status
Recruiting
Facility Name
EDUMED s.r.o.
City
Hradec Králové
ZIP/Postal Code
500 02
Country
Czechia
Individual Site Status
Recruiting
Facility Name
Fakultní nemocnice Hradec Králové
City
Hradec Králové
ZIP/Postal Code
500-05
Country
Czechia
Individual Site Status
Recruiting
Facility Name
EDUMED s.r.o.
City
Náchod
ZIP/Postal Code
547 01
Country
Czechia
Individual Site Status
Recruiting
Facility Name
Fakultni nemocnice Ostrava
City
Ostrava
ZIP/Postal Code
70852
Country
Czechia
Individual Site Status
Recruiting
Facility Name
Vseobecna fakultni nemocnice
City
Prague
ZIP/Postal Code
128 08
Country
Czechia
Individual Site Status
Recruiting
Facility Name
Lekarna Poliklinika Hurka
City
Prague
ZIP/Postal Code
15800
Country
Czechia
Individual Site Status
Recruiting
Facility Name
Interni Ambulance
City
Uherské Hradiště
ZIP/Postal Code
686 01
Country
Czechia
Individual Site Status
Recruiting
Facility Name
Aalborg University Hospital
City
Aalborg
ZIP/Postal Code
9000
Country
Denmark
Individual Site Status
Recruiting
Facility Name
Aarhus University Hospital
City
Aarhus
ZIP/Postal Code
8200
Country
Denmark
Individual Site Status
Recruiting
Facility Name
Esbjerg Hospital
City
Esbjerg
ZIP/Postal Code
6700
Country
Denmark
Individual Site Status
Recruiting
Facility Name
Bispebjerg Hospital
City
Frederiksberg
ZIP/Postal Code
2000
Country
Denmark
Individual Site Status
Recruiting
Facility Name
Herlev Hospital
City
Herlev
ZIP/Postal Code
2730
Country
Denmark
Individual Site Status
Recruiting
Facility Name
Godstrup Regional Hospital
City
Herning
ZIP/Postal Code
7400
Country
Denmark
Individual Site Status
Recruiting
Facility Name
Regionshospitalet Viborg
City
Viborg
ZIP/Postal Code
8800
Country
Denmark
Individual Site Status
Recruiting
Facility Name
Turku University Hospital
City
Turku
ZIP/Postal Code
20520
Country
Finland
Individual Site Status
Recruiting
Facility Name
Ylitornio Health Care Center
City
Ylitornio
ZIP/Postal Code
95600
Country
Finland
Individual Site Status
Recruiting
Facility Name
Hôpital Louis Pradel
City
Bron
ZIP/Postal Code
69677
Country
France
Individual Site Status
Recruiting
Facility Name
CHU Dijon Bourgogne
City
Dijon
ZIP/Postal Code
21079
Country
France
Individual Site Status
Recruiting
Facility Name
Hopital de la Conception
City
Marseille
ZIP/Postal Code
13005
Country
France
Individual Site Status
Recruiting
Facility Name
CHU Montpellier - Hôpital Lapeyronie
City
Montpellier
ZIP/Postal Code
34295
Country
France
Individual Site Status
Recruiting
Facility Name
Hopital Pitie Salpetriere APHP
City
Paris
ZIP/Postal Code
75013
Country
France
Individual Site Status
Recruiting
Facility Name
CHU Nantes - Hopital Nord Laennec
City
Saint-Herblain
ZIP/Postal Code
44093
Country
France
Individual Site Status
Recruiting
Facility Name
Stoffwechselcentrum Charite Campus Virchow
City
Berlin
ZIP/Postal Code
13353
Country
Germany
Individual Site Status
Recruiting
Facility Name
Universitaetsklinikum Carl Gustav Carus an der TU Dresden
City
Dresden
ZIP/Postal Code
1307
Country
Germany
Individual Site Status
Recruiting
Facility Name
St. Josefskrankenhaus,
City
Heidelberg
ZIP/Postal Code
69115
Country
Germany
Individual Site Status
Recruiting
Facility Name
Uniklinik Köln
City
Köln
ZIP/Postal Code
50937
Country
Germany
Individual Site Status
Recruiting
Facility Name
Praxis Dr. med. Taggeselle
City
Markkleeberg
ZIP/Postal Code
04416
Country
Germany
Individual Site Status
Recruiting
Facility Name
BKS Research Kft
City
Hatvan
State/Province
Heves
ZIP/Postal Code
3000
Country
Hungary
Individual Site Status
Recruiting
Facility Name
Medifarma 98 Kft
City
Nyíregyháza
State/Province
Szabolcs-Szatmar-Bereg
ZIP/Postal Code
4400
Country
Hungary
Individual Site Status
Recruiting
Facility Name
CRU Hungary Kft
City
Borsod
ZIP/Postal Code
3860
Country
Hungary
Individual Site Status
Recruiting
Facility Name
Semmelweis Egyetem Kardiológiai Rehabilitacio
City
Budapest
ZIP/Postal Code
H-1085
Country
Hungary
Individual Site Status
Recruiting
Facility Name
Belinus BT
City
Debrecen
ZIP/Postal Code
4025
Country
Hungary
Individual Site Status
Recruiting
Facility Name
Debreceni Egyetem Klinikai Kozpont Belgyogyaszat A epulet
City
Debrecen
ZIP/Postal Code
4032
Country
Hungary
Individual Site Status
Recruiting
Facility Name
IPR Hungary Kft.
City
Miskolc
ZIP/Postal Code
H-3530
Country
Hungary
Individual Site Status
Recruiting
Facility Name
Borbanya Praxis Eü KFT
City
Nyíregyháza
ZIP/Postal Code
4405
Country
Hungary
Individual Site Status
Recruiting
Facility Name
Fejer Megyei Szent Gyorgy Egyetemi Oktato Korhaz
City
Szekesfehervar
ZIP/Postal Code
8000
Country
Hungary
Individual Site Status
Recruiting
Facility Name
DRC Gyogyszervizsgalo Kozpont Kft
City
Veszprém
ZIP/Postal Code
8230
Country
Hungary
Individual Site Status
Recruiting
Facility Name
SOROKA Medical Center
City
Be'er Sheva
ZIP/Postal Code
8410101
Country
Israel
Individual Site Status
Recruiting
Facility Name
Lady Davis Carmel Medical Center
City
Haifa
ZIP/Postal Code
3436212
Country
Israel
Individual Site Status
Recruiting
Facility Name
Shaare Zedek Medical Center
City
Jerusalem
ZIP/Postal Code
9103102
Country
Israel
Individual Site Status
Recruiting
Facility Name
Hadassah Hebrew University Ein Kerm MC
City
Jerusalem
ZIP/Postal Code
91120
Country
Israel
Individual Site Status
Recruiting
Facility Name
Rabin Medical Center
City
Petach Tikva
ZIP/Postal Code
4941492
Country
Israel
Individual Site Status
Recruiting
Facility Name
Kaplan Medical Center
City
Reẖovot
ZIP/Postal Code
7661041
Country
Israel
Individual Site Status
Recruiting
Facility Name
Sheba Medical Center
City
Tel HaShomer
ZIP/Postal Code
5265601
Country
Israel
Individual Site Status
Recruiting
Facility Name
IRCCS Azienda Ospedaliero Universitaria di Bologna Policlinico di SantOrsola
City
Bologna
ZIP/Postal Code
40138
Country
Italy
Individual Site Status
Recruiting
Facility Name
Ospdale E. Bassini
City
Milano
ZIP/Postal Code
20092
Country
Italy
Individual Site Status
Recruiting
Facility Name
ASST Grande Ospedale Metropolitano Niguarda
City
Milano
ZIP/Postal Code
20162
Country
Italy
Individual Site Status
Recruiting
Facility Name
Azienda Ospedaliera Universitaria Federico II
City
Napoli
ZIP/Postal Code
80131
Country
Italy
Individual Site Status
Recruiting
Facility Name
A.O. Policlinico Universitario P. Giaccone
City
Palermo
ZIP/Postal Code
90127
Country
Italy
Individual Site Status
Recruiting
Facility Name
Policlinico Umberto
City
Roma
ZIP/Postal Code
00161
Country
Italy
Individual Site Status
Recruiting
Facility Name
Fondazione Policlinico Universitario A. Gemelli IRCCS - Universita Cattolica del Sacro Cuore
City
Roma
ZIP/Postal Code
00168
Country
Italy
Individual Site Status
Recruiting
Facility Name
Academic Medical Center - Department of Vascular Medicine
City
Amsterdam
ZIP/Postal Code
1105 AZ
Country
Netherlands
Individual Site Status
Recruiting
Facility Name
Rijnstate Arnhem
City
Arnhem
ZIP/Postal Code
6815 AD
Country
Netherlands
Individual Site Status
Recruiting
Facility Name
Albert Schweitzer ziekenhuis
City
Dordrecht
ZIP/Postal Code
3318 AT
Country
Netherlands
Individual Site Status
Recruiting
Facility Name
Ziekenhuis Gelderse Vallei
City
Ede
ZIP/Postal Code
6716 RP
Country
Netherlands
Individual Site Status
Recruiting
Facility Name
Radboud UMC
City
Nijmegen
ZIP/Postal Code
6525 GA
Country
Netherlands
Individual Site Status
Recruiting
Facility Name
Erasmus MC
City
Rotterdam
ZIP/Postal Code
3015 GD
Country
Netherlands
Individual Site Status
Recruiting
Facility Name
Universitair Medisch Centrum Utrecht
City
Utrecht
ZIP/Postal Code
3584 CX
Country
Netherlands
Individual Site Status
Recruiting
Facility Name
Auckland City Hospital
City
Grafton
State/Province
Auckland
ZIP/Postal Code
1010
Country
New Zealand
Individual Site Status
Recruiting
Facility Name
New Zealand Clinical Research
City
Christchurch
ZIP/Postal Code
8011
Country
New Zealand
Individual Site Status
Recruiting
Facility Name
Wellington Regional Hospital
City
Newtown
ZIP/Postal Code
6021
Country
New Zealand
Individual Site Status
Recruiting
Facility Name
Lipid Clinic
City
Oslo
ZIP/Postal Code
0586
Country
Norway
Individual Site Status
Recruiting
Facility Name
Salvia
City
Katowice
ZIP/Postal Code
40-772
Country
Poland
Individual Site Status
Recruiting
Facility Name
Praktyka Lekarska Ewa Krzyzagorska
City
Poznan
ZIP/Postal Code
61-655
Country
Poland
Individual Site Status
Recruiting
Facility Name
ClinMedica Research Sp.z o.o.
City
Skierniewice
ZIP/Postal Code
96-100
Country
Poland
Individual Site Status
Recruiting
Facility Name
Futuremeds sp. z o.o
City
Wroclaw
ZIP/Postal Code
50-088
Country
Poland
Individual Site Status
Recruiting
Facility Name
Instytut Centrum Zdrowia Matki Polki Klinika
City
Łódz
ZIP/Postal Code
93-338
Country
Poland
Individual Site Status
Recruiting
Facility Name
Centro Hospitalar do Baixo Vouga Hospital Infante D. Pedro
City
Aveiro
ZIP/Postal Code
3814-501
Country
Portugal
Individual Site Status
Recruiting
Facility Name
Centro Hospitalar e Universitário de Coimbra, EPE
City
Coimbra
ZIP/Postal Code
3004-561
Country
Portugal
Individual Site Status
Recruiting
Facility Name
Hospital Egas Moniz - Centro Hospitalar de Lisboa Ocidental
City
Lisbon
ZIP/Postal Code
1349-019
Country
Portugal
Individual Site Status
Recruiting
Facility Name
Centro Hospitalar Universitário de São João Consultas Externas de Endocrinologia K13
City
Porto
ZIP/Postal Code
4200-319
Country
Portugal
Individual Site Status
Recruiting
Facility Name
Centro Hospitalar
City
Vila Nova De Gaia
ZIP/Postal Code
4434-502
Country
Portugal
Individual Site Status
Recruiting
Facility Name
Nemocnica s poliklinikou Brezno
City
Brezno
ZIP/Postal Code
97701
Country
Slovakia
Individual Site Status
Recruiting
Facility Name
Vychodoslovensky Ustav srdcovych a cievnych chorob a.s.
City
Kosice
ZIP/Postal Code
040 11
Country
Slovakia
Individual Site Status
Recruiting
Facility Name
Human-Care s.r.o.
City
Košice
ZIP/Postal Code
040 01
Country
Slovakia
Individual Site Status
Recruiting
Facility Name
Cardio D&R
City
Košice
ZIP/Postal Code
040 22
Country
Slovakia
Individual Site Status
Recruiting
Facility Name
Iatros International
City
Bloemfontein
State/Province
Free State
ZIP/Postal Code
9301
Country
South Africa
Individual Site Status
Recruiting
Facility Name
Unitas Hospital
City
Centurion
State/Province
Gauteng
ZIP/Postal Code
157
Country
South Africa
Individual Site Status
Recruiting
Facility Name
Dr Jan Engelbrecht and Ass. Inc
City
Cape Town
State/Province
Western Cape
ZIP/Postal Code
7130
Country
South Africa
Individual Site Status
Recruiting
Facility Name
TREAD Research - Department of Cardiology
City
Parow
State/Province
Western Cape
ZIP/Postal Code
7500
Country
South Africa
Individual Site Status
Recruiting
Facility Name
University of Cape town - Lipid Factory
City
Cape Town
ZIP/Postal Code
7925
Country
South Africa
Individual Site Status
Recruiting
Facility Name
Chatsmed Garden Hospital
City
Chatsworth
ZIP/Postal Code
4092
Country
South Africa
Individual Site Status
Recruiting
Facility Name
Hospital Abente y Lago
City
A Coruña
ZIP/Postal Code
15001
Country
Spain
Individual Site Status
Recruiting
Facility Name
Hospital de la Santa Creu i de Sant Pau
City
Barcelona
ZIP/Postal Code
08041
Country
Spain
Individual Site Status
Recruiting
Facility Name
Hospital Clinic Barcelona
City
Barcelona
ZIP/Postal Code
8063
Country
Spain
Individual Site Status
Recruiting
Facility Name
Institut d'Investigació i Innovació Parc Taulí (I3PT) Departament Medicina Universitat
City
Barcelona
ZIP/Postal Code
8208
Country
Spain
Individual Site Status
Recruiting
Facility Name
Hospital Universitari de Bellvitge
City
Barcelona
ZIP/Postal Code
8907
Country
Spain
Individual Site Status
Recruiting
Facility Name
Hospital Universitario Reina Sofia
City
Córdoba
ZIP/Postal Code
14004
Country
Spain
Individual Site Status
Recruiting
Facility Name
Hospital Universitario
City
Madrid
ZIP/Postal Code
28041
Country
Spain
Individual Site Status
Recruiting
Facility Name
Hospital Virgen del Rocio Edificio Centro de Diagnostico y Tratamiento (CDT)
City
Sevilla
ZIP/Postal Code
41013
Country
Spain
Individual Site Status
Recruiting
Facility Name
Hospital Universitari Sant Joan de Reus.
City
Tarragona
ZIP/Postal Code
43204
Country
Spain
Individual Site Status
Recruiting
Facility Name
Sahlgrenska, University Hospital
City
Goteborg
State/Province
Västra Götalands Län
ZIP/Postal Code
413 45
Country
Sweden
Individual Site Status
Recruiting
Facility Name
Karolinska University Hospital Huddinge
City
Stockholm
ZIP/Postal Code
14186
Country
Sweden
Individual Site Status
Recruiting
Facility Name
Hacettepe University Medical Faculty
City
Ankara
ZIP/Postal Code
06230
Country
Turkey
Individual Site Status
Recruiting
Facility Name
Kocaeli University Faculty of Medicine
City
Kocaeli
ZIP/Postal Code
41380
Country
Turkey
Individual Site Status
Recruiting
Facility Name
Necmettin Erbakan University Meram Medical Faculty
City
Konya
ZIP/Postal Code
42280
Country
Turkey
Individual Site Status
Recruiting
Facility Name
Oak Tree Surgery and Pensilva Health Centre
City
Liskeard
State/Province
Cornwall
ZIP/Postal Code
PL14 3XA
Country
United Kingdom
Individual Site Status
Recruiting
Facility Name
Newquay Health Centre
City
Newquay
State/Province
Cornwall
ZIP/Postal Code
TR7 1RU
Country
United Kingdom
Individual Site Status
Recruiting
Facility Name
Panthera Biopartners
City
Rochdale
State/Province
England
ZIP/Postal Code
OL11 4AU
Country
United Kingdom
Individual Site Status
Recruiting
Facility Name
Panthera Biopartners
City
Sheffield
State/Province
England
ZIP/Postal Code
S2 5FX
Country
United Kingdom
Individual Site Status
Recruiting
Facility Name
Huddersfield Royal Infirmary
City
Lindley
State/Province
Huddersfield
ZIP/Postal Code
HD3 3EA
Country
United Kingdom
Individual Site Status
Recruiting
Facility Name
Sandwell General Hospital
City
Lyne
State/Province
West Bromwich
ZIP/Postal Code
B71 4HJ
Country
United Kingdom
Individual Site Status
Recruiting
Facility Name
Waterloo Medical Centre
City
Blackpool
ZIP/Postal Code
FY4 3AD
Country
United Kingdom
Individual Site Status
Recruiting
Facility Name
Panthera
City
Glasgow
ZIP/Postal Code
G51 4TY
Country
United Kingdom
Individual Site Status
Recruiting
Facility Name
Hull Royal Infirmary
City
Hull
ZIP/Postal Code
HU3 2JZ
Country
United Kingdom
Individual Site Status
Recruiting
Facility Name
Panthera
City
London
ZIP/Postal Code
EN3 4GS
Country
United Kingdom
Individual Site Status
Recruiting
Facility Name
Panthera
City
Preston
ZIP/Postal Code
PR2 9QB
Country
United Kingdom
Individual Site Status
Recruiting

12. IPD Sharing Statement

Plan to Share IPD
No

Learn more about this trial

A Study of Olezarsen (ISIS 678354) Administered to Participants With Severe Hypertriglyceridemia

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