Strategies for Endocervical Canal Investigation in Women With Abnormal Screening Cytology and Negative Colposcopy
Diagnoses Disease, Screening, HSIL of Cervix
About this trial
This is an interventional prevention trial for Diagnoses Disease focused on measuring Diagnostic Methods, Additional Endocervical Brushing, Endocervical canal curettage, Screening and Prevention Cervical Cancer, Precancer lesion
Eligibility Criteria
Inclusion Criteria:
- women aged 25 years or older with altered cytology (ASC-H+) and attended the care unit and who consented to participate in the study by signing the Informed Consent Form
- Non-pregnant
Exclusion Criteria:
- colposcopy with abnormal findings;
- total hysterectomy (extirpation of the cervix);
- cervical stenosis or imperviousness near the external orifice.
Sites / Locations
- Hospital de Cancer de Barretos
- Sandra Moretti Jusselino Maniçoba Palopoli
- Hospital de Cancer de Barretos
- Hospital de Cancer de Barretos
Arms of the Study
Arm 1
Arm 2
Arm 3
Active Comparator
Active Comparator
Active Comparator
Endocervical cytology performed by liquid-based cytology
Endocervical cell block from a canal sample preserved in a buffered formalin base
Endocervical curettage
Endocervical sample collected by brushing and preserved in a liquid base, and evaluated as cytology.
Endocervical sample collected by brushing and preserved in a buffered formalin base for obtaining a "cell block", and evaluated similarly as histology.
Endocervical curettage sample preserved in buffered formalin and evaluated by histology.