A Study of Acute Respiratory Infections in Global Outpatient Setting (ARGOS)
Acute Respiratory Infection
About this trial
This is an interventional other trial for Acute Respiratory Infection focused on measuring Respiratory syncytial virus (RSV), Flu, COVID-19
Eligibility Criteria
Inclusion Criteria:
- Present to the general physician (GP)/specialist outpatient settings/respiratory clinics or in Emergency department (ED) settings with symptoms suggestive of a diagnosis of Acute Respiratory Infections (ARI)
- For inclusion in the home-based follow-up phases, must test positive for respiratory syncytial virus (RSV) and/or influenza and/or Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) per a molecular-based diagnostic assay (polymerase chain reaction [PCR]-based) using a nasal swab (nasopharyngeal or similar) sample. Co-infections are permitted to be enrolled in the study
- Must be able to read, understand, and complete questionnaires
- Must be willing to provide verifiable identification, has means to be contacted and to contact the investigator during the study
- Willing and able to adhere to the specifications in this protocol
Exclusion Criteria:
- Has a clinical condition other than those as specified in study protocol which, in the opinion of the investigator, could prevent, confound, or limit the protocol-specified assessments
- Received an investigational drug (including investigational vaccines) within 3 months before the start of the study or the first data collection time-point
- Is currently enrolled or plans to participate in another investigational study on RSV, influenza or SARS-CoV-2 during the current study
- Is, in the opinion of the investigator, unlikely to adhere to the requirements of the study, or is unlikely to complete the full course of observation
- Cannot communicate reliably with the investigator
Sites / Locations
- Central Alabama Research
- Lakeview Clinical Research
- Synexus Clinical Research US, Inc
- Fiel Family and Sports Medicine Clinical Research Advantage
- Harrisburg Family Medical Center
- Innovative Research of West Florida, Incorporated
- New Life Medical Research Center, Inc.
- Best Quality Research Inc
- PharmaDUX Clinical Medical Research, LLC
- Homestead Associates in Research,Inc
- Alma Clinical Research
- Research Institute of South Florida Inc
- Pines Care Research Center Inc
- Santos Research Center
- Columbus Regional Research Institute
- IACT Health
- Snake River Research, PLLC
- Washington University School of Medicine
- Montana Medical Research
- Healor Primary Care
- Las Vegas Medical Research
- Santa Rosa Medical Centers of Nevada
- Urgent Care Clinical Trials at AFC Urgent Care
- Montefiore Medical Center
- American Health Network, LLC
- Duke University Medical Center
- DayStar Clinical Research, Inc.
- Urgent Care Clinical Trials at AFC Urgent Care
- Premier Family Physicians
- Next Level Urgent Care
- Southwest Family Medicine Associates
- Urgent Care Clinical Trials Fort Worth
- Southwest Clinical Trials
- Renovatio Clinical
- Benchmark Research
- CCT Research at Olympus Family Medicine
- CCT Research at South Ogden Family Medicine
- Clinical Research Partners, LLC
- IACT Health
- ALTA Clinical Research Inc.
- CHU Grenoble
- Hopital Edouard Herriot - CHU Lyon
- CHU Nimes - Hôpital Carémeau
- Fujita Health University Hospital
- Hanasaki Clinic
- Miyagikoseikyokai Saka General Hospital
- Inje University Busan Paik Hospital
- Korea University Ansan Hospital
- Gachon University Gil Medical Center
- Hallym University Kangnam Sacred Heart Hospital
- Klinik Kesihatan Putrajaya Presint 9
- Klinik Kesihatan Kuang
- Klinik Kesihatan Masjid Tanah
- Hospital Miri
- Gabinet Lekarski Pediatryczno-Alergologiczny
- NEURO-MEDIC Janusz Zbrojkiewicz Poradnia Wielospecjalistyczna
- ETG Lodz
- EMC Instytut Medyczny SA PL CERTUS
- NZOZ Leczniczo-Rehabilitacyjny Ośrodek Medycyny Rodzinnej
- Cs Algeciras Norte
- Hosp. Gral. Univ. de Alicante
- Eap Sardenya
- Cap Apenins - Montigala
- Cap Canet de Mar
- Hosp. Clinico San Carlos
- Kaohsiung Medical University Chung-Ho Memorial Hospital
- Taipei Medical University Shuang Ho Hospital
- Taipei Medical University
- Taipei Veterans General Hospital
- Tri-Service General Hospital
- Taipei Municipal Wanfang Hospital
- The Adam Practice
Arms of the Study
Arm 1
Other
Participants with Acute Respiratory Infections (ARI) in Outpatient Setting
Participants presenting with ARIs in an outpatient setting who are at high risk of progressing to severe disease will be screened for viral respiratory pathogens (respiratory syncytial virus [RSV], Influenza, severe acute respiratory syndrome coronavirus 2 [SARS-COV-2]) by collecting a nasal swab. If a participant is positive for RSV and/or influenza virus and/or SARS-CoV-2 based on a study test or standard-of-care (SOC) polymerase chain reaction (PCR)-based test, the participant will be eligible for enrollment in the study in the home-based short-term and long-term follow-up phases.