RESET-psychotherapy: the Effectiveness of Trauma-focused Therapy in Patients With Depression and Childhood Trauma
Major Depressive Disorder, Childhood Trauma
About this trial
This is an interventional treatment trial for Major Depressive Disorder focused on measuring Depression, Childhood trauma, Trauma-focused, Psychotherapy, Treatment, EMDR, Imagery rescripting
Eligibility Criteria
Inclusion Criteria:
- Moderate to severe depression, defined by a score ≥ 26 on the Inventory of Depressive Symptomatology - Self Rated (IDS-SR)
- DSM-5 diagnosis of MDD confirmed with the Dutch translation of the MINI-S for DSM-5
Moderate to severe childhood trauma (CT) before the age of 18, defined by a score above validated cut-off on one or more of the following domains of the 28-item Childhood Trauma Questionnaire Short Form (CTQ-SF):
- physical neglect: score ≥ 10
- emotional neglect: score ≥ 15
- sexual abuse: score ≥ 8
- physical abuse: score ≥10
- emotional abuse: score ≥ 13
- Sufficient mastery of Dutch language
Exclusion Criteria:
- Previous TFT on CT
- Other lifetime severe psychiatric comorbidity (bipolar disorder, psychotic disorder)
- Current alcohol/drug dependence
- Primary diagnosis of post-traumatic stress disorder (PTSD) or Acute Stress Disorder (ASD)
- Lifetime diagnosis of borderline personality disorder (BPD)
Sites / Locations
- GGZ inGeestRecruiting
- HSK GroepRecruiting
- Altrecht
Arms of the Study
Arm 1
Arm 2
Active Comparator
Experimental
Treatment as usual (TAU)
Treatment as usual (TAU) + Trauma-focused therapy (TFT)
Participants will receive an evidence-based psychotherapeutic intervention combined with/or pharmacotherapy (TAU)
Participants will receive 6 to 10, 60-90 minute TFT sessions delivered over a period of 12 weeks, in addition to TAU.