Transcutaneous Electrical Nerve Stimulation for Endometriosis-related Chronic Pain
Endometriosis-related Pain
About this trial
This is an interventional treatment trial for Endometriosis-related Pain focused on measuring Endometriosis, Chronic pain, Transcutaneous electrical nerve stimulation
Eligibility Criteria
Inclusion Criteria:
- Age ≥18 years
- Consents to participation in the study
- Verified endometriosis (by laparoscopy or ultrasound).
- Chronic endometriosis-related pain (> 3 months), available for TENS treatment
- Functioning, stable endometriosis-specific hormonal drug therapy. The endometriosis-specific drug therapy must be unchanged for the last 3 months and no gynecological surgical procedures for the treatment of endometriosis are planned during the next 7 months (during study participation). The endometriosis-specific drug therapy does not refer to analgesic therapy for symptom relief of endometriosis-related pain.
Exclusion Criteria:
- Patient with inability to understand and use written and spoken Swedish
- Patient with pacemaker and/or ICD or other electronic implants
- Patient with impaired sensation over the painful area
- Malignant disease with an expected survival <12 months
- Alcohol or substance abuse
- Serious untreated psychiatric illness and/or psychological condition that is the primary determinant of the patient's condition
- Participating in another intervention study with possible impact on current study outcome measures
- Patient who is using >90 morphine equivalents/day
- Patient who is electro-acupuncture
- Pregnancy
Sites / Locations
- Pain Centre, Department of Anaesthesiology and Intensive Care Medicine Östra, Sahlgrenska University Hospital, Region Västra GötalandRecruiting
Arms of the Study
Arm 1
Arm 2
Arm 3
Active Comparator
Active Comparator
Active Comparator
TENS (transcutaneous electrical nerve stimulation)
Conventional analgesic treatment
External control group
Patients with endometriosis-related chronic frequent pain and high pain intensity (≥ 4 according to Numeric Rating Scale, NRS) randomized to transcutaneous electrical nerve stimulation as add-on treatment in addition to conventional analgesic treatment. Treatment with transcutaneous electrical nerve stimulation (TENS) during 16 weeks.
Patients with endometriosis related chronic frequent pain and high pain intensity (≥ 4 according to Numeric Rating Scale, NRS) randomized to conventional analgesic treatment for 8 weeks. After 8 weeks the patients are treated with transcutaneous electrical nerve stimulation (TENS) during 16 weeks.
Patients with endometriosis-related pain that is not frequent or without high pain intensity (< 4 according to Numeric Rating Scale, NRS) constitute an external control group. The patients are treated with transcutaneous electrical nerve stimulation as add-on treatment in addition to conventional analgesic treatment. Treatment with transcutaneous electrical nerve stimulation (TENS) during 16 weeks.