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A Study of BMS-986218 or BMS-986218 Plus Nivolumab in Combination With Docetaxel in Participants With Metastatic Castration-resistant Prostate Cancer

Primary Purpose

Prostatic Neoplasms, Castration-Resistant

Status
Recruiting
Phase
Phase 2
Locations
International
Study Type
Interventional
Intervention
BMS-986218
Docetaxel
Nivolumab
Sponsored by
Bristol-Myers Squibb
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional treatment trial for Prostatic Neoplasms, Castration-Resistant focused on measuring BMS-986218, BMS-936558, Docetaxel, Metastatic, MDX1106, Nivolumab, ONO-4538, TAXOTERE

Eligibility Criteria

18 Years - undefined (Adult, Older Adult)MaleDoes not accept healthy volunteers

Inclusion Criteria:

  • Histologic confirmation of carcinoma of the prostate without small cell features
  • Documented prostate cancer progression by Prostate Cancer Working Group 3 (PCWG3) criteria while castrate
  • Evidence of metastatic disease documented by either bone lesions on radionuclide bone scan and/or soft tissue lesions on computed tomography (CT)/magnetic resonance imaging (MRI)
  • Eastern Cooperative Oncology Group (ECOG) performance status 0 to 1
  • Ongoing androgen deprivation therapy (ADT) with a gonadotropin-releasing hormone (GnRH) agonist/antagonist or bilateral orchiectomy (i.e., surgical or medical castration) confirmed by testosterone level ≤ 1.73 nmol/L (50 ng/dL) at the screening visit
  • Chemotherapy-naive for metastatic castration-resistant prostate cancer (mCRPC) and have received at least one novel antiandrogen therapy (NAT)

Exclusion Criteria:

  • Concurrent malignancy (present during screening) requiring treatment or history of prior malignancy active within 2 years prior to treatment assignment in Part 1 or randomization in Part 2
  • Untreated central nervous system (CNS) metastases
  • Leptomeningeal metastases
  • Active, known or suspected autoimmune disease

Other protocol-defined inclusion/exclusion criteria apply

Sites / Locations

  • Arizona Oncology - Tucson - Wilmot Road LocationRecruiting
  • Kaiser Permanente Los Angeles Medical Center
  • Rocky Mountain Cancer Centers - LittletonRecruiting
  • Yale School Of Medicine
  • Medical Oncology Hematology Consultants - NewarkRecruiting
  • The Winship Cancer Institute of Emory University
  • Northwest Georgia Oncology Centers, P.C.Recruiting
  • The University of Chicago Medical Center - Duchossois Center for Advanced Medicine
  • University Of Iowa Hospitals And Clinics
  • University of Iowa Hospitals and Clinics
  • The Johns Hopkins Hospital
  • Washington University School of Medicine in St. Louis
  • Columbia University Medical Center - Herbert Irving Pavilion LocationRecruiting
  • Duke Cancer Institute
  • Oncology Hematology Care, Inc. - EastgateRecruiting
  • Willamette Valley Cancer InstituteRecruiting
  • Texas Oncology-Beaumont Mamie McFaddin Ward Cancer CenterRecruiting
  • Texas OncologyRecruiting
  • Texas Oncology - Denton NorthRecruiting
  • Texas OncologyRecruiting
  • Texas Oncology - Fort Worth Cancer CenterRecruiting
  • The University of Texas - MD Anderson Cancer Center - Genitourinary (GU) Cancer CenterRecruiting
  • Texas Oncology - McKinneyRecruiting
  • Texas Oncology- TylerRecruiting
  • Virginia Oncology Associates - HamptonRecruiting
  • Medical College of Wisconsin
  • Local Institution - 0070
  • Local Institution - 0055
  • Local Institution - 0025
  • Local Institution - 0039
  • Local Institution - 0046
  • Local Institution - 0041
  • Local Institution - 0062
  • Local Institution - 0019
  • Local Institution - 0066
  • Local Institution - 0078
  • Local Institution - 0067
  • Local Institution - 0083
  • Local Institution - 0028
  • Local Institution - 0015
  • Local Institution - 0086
  • Local Institution - 0011
  • Local Institution - 0080
  • Local Institution - 0031
  • Local Institution - 0023
  • Local Institution - 0008
  • Local Institution - 0076
  • Local Institution - 0012
  • Local Institution - 0049
  • Local Institution - 0003
  • Local Institution - 0014
  • Local Institution - 0081
  • Local Institution - 0010
  • Local Institution - 0027
  • Local Institution - 0007
  • Local Institution - 0054
  • Local Institution - 0032
  • Local Institution - 0077
  • Local Institution - 0069
  • Local Institution - 0037
  • Local Institution - 0021
  • Local Institution - 0071
  • Local Institution - 0016
  • Local Institution - 0029
  • Local Institution - 0072
  • Local Institution - 0074
  • Local Institution - 0002
  • Local Institution - 0009
  • Local Institution - 0079
  • Local Institution - 0068
  • Local Institution - 0017
  • Local Institution - 0075
  • Local Institution - 0065
  • Local Institution - 0064
  • Local Institution - 0030
  • Local Institution - 0048
  • Local Institution - 0053
  • Local Institution - 0051
  • Local Institution - 0073
  • Local Institution - 0013
  • Local Institution - 0035
  • Local Institution - 0063

Arms of the Study

Arm 1

Arm 2

Arm 3

Arm 4

Arm 5

Arm 6

Arm Type

Experimental

Experimental

Experimental

Experimental

Experimental

Experimental

Arm Label

Arm 1A: Docetaxel + BMS-986218

Arm 1B: Docetaxel + BMS-986218 + Nivolumab

Arm 2A: Docetaxel

Arm 2B: Docetaxel + BMS-986218

Arm 2C: Docetaxel + BMS-986218 + Nivolumab

Arm 2D (Optional Crossover): BMS-986218 + Nivolumab

Arm Description

Outcomes

Primary Outcome Measures

Number of participants with adverse events (AEs)
Part 1
Number of deaths
Part 1
Radiographic progression-free survival (rPFS) assessed by blinded independent central review (BICR) per Prostate Cancer Working Group 3 (PCWG3)
Part 2

Secondary Outcome Measures

Objective response rate per Prostate Cancer Working Group 3 (ORR-PCWG3)
Part 2
Time to response per Prostate Cancer Working Group 3 (TTR-PCWG3) as determined by BICR
Part 2
Duration of response per Prostate Cancer Working Group 3 (DOR-PCWG3) as determined by BICR
Part 2
Prostate-specific antigen response rate (PSA-RR)
Part 2
Time to prostate-specific antigen progression (TTP-PSA) per PCWG3
Part 2
Overall survival (OS)
Part 2
Number of participants with adverse events (AEs)
Part 2
Number of deaths
Part 2

Full Information

First Posted
December 10, 2021
Last Updated
October 18, 2023
Sponsor
Bristol-Myers Squibb
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1. Study Identification

Unique Protocol Identification Number
NCT05169684
Brief Title
A Study of BMS-986218 or BMS-986218 Plus Nivolumab in Combination With Docetaxel in Participants With Metastatic Castration-resistant Prostate Cancer
Official Title
A Phase 2, Open-label, Randomized Controlled Trial of BMS-986218 or BMS-986218 Plus Nivolumab in Combination With Docetaxel in Participants With Metastatic Castration-resistant Prostate Cancer
Study Type
Interventional

2. Study Status

Record Verification Date
October 2023
Overall Recruitment Status
Recruiting
Study Start Date
February 14, 2022 (Actual)
Primary Completion Date
February 12, 2026 (Anticipated)
Study Completion Date
February 13, 2026 (Anticipated)

3. Sponsor/Collaborators

Responsible Party, by Official Title
Sponsor
Name of the Sponsor
Bristol-Myers Squibb

4. Oversight

Studies a U.S. FDA-regulated Drug Product
Yes
Studies a U.S. FDA-regulated Device Product
No
Data Monitoring Committee
Yes

5. Study Description

Brief Summary
The purpose of this study is to assess the safety, efficacy, tolerability, and toxicity of docetaxel alone, in combination with BMS-986218, or in combination with nivolumab plus BMS-986218 in men who have metastatic castration-resistant prostate cancer (mCRPC) that progressed after novel antiandrogen therapy and have not received chemotherapy for mCRPC.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Prostatic Neoplasms, Castration-Resistant
Keywords
BMS-986218, BMS-936558, Docetaxel, Metastatic, MDX1106, Nivolumab, ONO-4538, TAXOTERE

7. Study Design

Primary Purpose
Treatment
Study Phase
Phase 2
Interventional Study Model
Sequential Assignment
Masking
None (Open Label)
Allocation
Randomized
Enrollment
204 (Anticipated)

8. Arms, Groups, and Interventions

Arm Title
Arm 1A: Docetaxel + BMS-986218
Arm Type
Experimental
Arm Title
Arm 1B: Docetaxel + BMS-986218 + Nivolumab
Arm Type
Experimental
Arm Title
Arm 2A: Docetaxel
Arm Type
Experimental
Arm Title
Arm 2B: Docetaxel + BMS-986218
Arm Type
Experimental
Arm Title
Arm 2C: Docetaxel + BMS-986218 + Nivolumab
Arm Type
Experimental
Arm Title
Arm 2D (Optional Crossover): BMS-986218 + Nivolumab
Arm Type
Experimental
Intervention Type
Biological
Intervention Name(s)
BMS-986218
Intervention Description
Specified dose on specified days
Intervention Type
Drug
Intervention Name(s)
Docetaxel
Other Intervention Name(s)
TAXOTERE
Intervention Description
Specified dose on specified days
Intervention Type
Biological
Intervention Name(s)
Nivolumab
Other Intervention Name(s)
BMS-936558, MDX1106, ONO-4538
Intervention Description
Specified dose on specified days
Primary Outcome Measure Information:
Title
Number of participants with adverse events (AEs)
Description
Part 1
Time Frame
Up to 2 years
Title
Number of deaths
Description
Part 1
Time Frame
Up to 2 years
Title
Radiographic progression-free survival (rPFS) assessed by blinded independent central review (BICR) per Prostate Cancer Working Group 3 (PCWG3)
Description
Part 2
Time Frame
Up to 4 years
Secondary Outcome Measure Information:
Title
Objective response rate per Prostate Cancer Working Group 3 (ORR-PCWG3)
Description
Part 2
Time Frame
Up to 4 years
Title
Time to response per Prostate Cancer Working Group 3 (TTR-PCWG3) as determined by BICR
Description
Part 2
Time Frame
Up to 4 years
Title
Duration of response per Prostate Cancer Working Group 3 (DOR-PCWG3) as determined by BICR
Description
Part 2
Time Frame
Up to 4 years
Title
Prostate-specific antigen response rate (PSA-RR)
Description
Part 2
Time Frame
Up to 4 years
Title
Time to prostate-specific antigen progression (TTP-PSA) per PCWG3
Description
Part 2
Time Frame
Up to 4 years
Title
Overall survival (OS)
Description
Part 2
Time Frame
Up to 4 years
Title
Number of participants with adverse events (AEs)
Description
Part 2
Time Frame
Up to 2 years
Title
Number of deaths
Description
Part 2
Time Frame
Up to 2 years

10. Eligibility

Sex
Male
Minimum Age & Unit of Time
18 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria: Histologic confirmation of carcinoma of the prostate without small cell features Documented prostate cancer progression by Prostate Cancer Working Group 3 (PCWG3) criteria while castrate Evidence of metastatic disease documented by either bone lesions on radionuclide bone scan and/or soft tissue lesions on computed tomography (CT)/magnetic resonance imaging (MRI) Eastern Cooperative Oncology Group (ECOG) performance status 0 to 1 Ongoing androgen deprivation therapy (ADT) with a gonadotropin-releasing hormone (GnRH) agonist/antagonist or bilateral orchiectomy (i.e., surgical or medical castration) confirmed by testosterone level ≤ 1.73 nmol/L (50 ng/dL) at the screening visit Chemotherapy-naive for metastatic castration-resistant prostate cancer (mCRPC) and have received at least one novel antiandrogen therapy (NAT) Exclusion Criteria: Concurrent malignancy (present during screening) requiring treatment or history of prior malignancy active within 2 years prior to treatment assignment in Part 1 or randomization in Part 2 Untreated central nervous system (CNS) metastases Leptomeningeal metastases Active, known or suspected autoimmune disease Other protocol-defined inclusion/exclusion criteria apply
Central Contact Person:
First Name & Middle Initial & Last Name or Official Title & Degree
BMS Study Connect Contact Center www.BMSStudyConnect.com
Phone
855-907-3286
Email
Clinical.Trials@bms.com
First Name & Middle Initial & Last Name or Official Title & Degree
First line of the email MUST contain NCT # and Site #.
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Bristol-Myers Squibb
Organizational Affiliation
Bristol-Myers Squibb
Official's Role
Study Director
Facility Information:
Facility Name
Arizona Oncology - Tucson - Wilmot Road Location
City
Tucson
State/Province
Arizona
ZIP/Postal Code
85711-2701
Country
United States
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Aung Bajaj, Site 0043
Facility Name
Kaiser Permanente Los Angeles Medical Center
City
Los Angeles
State/Province
California
ZIP/Postal Code
90027-5969
Country
United States
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Helen Moon, Site 0033
Phone
951-353-3323
Facility Name
Rocky Mountain Cancer Centers - Littleton
City
Littleton
State/Province
Colorado
ZIP/Postal Code
80120-4413
Country
United States
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Manojkumar Bupathi, Site 0024
Phone
303-418-7639
Facility Name
Yale School Of Medicine
City
New Haven
State/Province
Connecticut
ZIP/Postal Code
06510-3206
Country
United States
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Daniel Petrylak, Site 0082
Phone
718-939-8655
Facility Name
Medical Oncology Hematology Consultants - Newark
City
Newark
State/Province
Delaware
ZIP/Postal Code
19713-2055
Country
United States
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Jamal Misleh, Site 0044
Facility Name
The Winship Cancer Institute of Emory University
City
Atlanta
State/Province
Georgia
ZIP/Postal Code
30322-1013
Country
United States
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Bradley Carthon, Site 0047
Phone
404-686-8210
Facility Name
Northwest Georgia Oncology Centers, P.C.
City
Marietta
State/Province
Georgia
ZIP/Postal Code
30060
Country
United States
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Steven McCune, Site 0004
Phone
770-281-5162
Facility Name
The University of Chicago Medical Center - Duchossois Center for Advanced Medicine
City
Chicago
State/Province
Illinois
ZIP/Postal Code
60637-1426
Country
United States
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Akash Patnaik, Site 0036
Phone
507-358-5327
Facility Name
University Of Iowa Hospitals And Clinics
City
Iowa City
State/Province
Iowa
ZIP/Postal Code
52242
Country
United States
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Rohan Garje, Site 0084
Phone
319-356-1770
Facility Name
University of Iowa Hospitals and Clinics
City
Iowa City
State/Province
Iowa
ZIP/Postal Code
52242
Country
United States
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Yousef Zakharia, Site 0085
Phone
319-384-8076
Facility Name
The Johns Hopkins Hospital
City
Baltimore
State/Province
Maryland
ZIP/Postal Code
21287
Country
United States
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Mark Markowski, Site 0061
Phone
410-614-4459
Facility Name
Washington University School of Medicine in St. Louis
City
Saint Louis
State/Province
Missouri
ZIP/Postal Code
63110-1010
Country
United States
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Russell Pachynski, Site 0001
Phone
314-286-2341
Facility Name
Columbia University Medical Center - Herbert Irving Pavilion Location
City
New York
State/Province
New York
ZIP/Postal Code
10032-3729
Country
United States
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Karie Runcie, Site 0006
Phone
212-305-8923
Facility Name
Duke Cancer Institute
City
Durham
State/Province
North Carolina
ZIP/Postal Code
27710
Country
United States
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Michael Harrison, Site 0005
Phone
919-668-4615
Facility Name
Oncology Hematology Care, Inc. - Eastgate
City
Cincinnati
State/Province
Ohio
ZIP/Postal Code
45245-1995
Country
United States
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Mark Johns, Site 0058
Facility Name
Willamette Valley Cancer Institute
City
Eugene
State/Province
Oregon
ZIP/Postal Code
97477
Country
United States
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Joseph Fiorillo, Site 0040
Phone
541-683-5001
Facility Name
Texas Oncology-Beaumont Mamie McFaddin Ward Cancer Center
City
Beaumont
State/Province
Texas
ZIP/Postal Code
77702
Country
United States
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Scott Mckenney, Site 0026
Phone
409-899-7180
Facility Name
Texas Oncology
City
Bedford
State/Province
Texas
ZIP/Postal Code
76022-6920
Country
United States
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Henrik Bo Illum, Site 0022
Phone
817-359-9000
Facility Name
Texas Oncology - Denton North
City
Denton
State/Province
Texas
ZIP/Postal Code
76201-4315
Country
United States
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Charles Kurkul, Site 0050
Facility Name
Texas Oncology
City
Flower Mound
State/Province
Texas
ZIP/Postal Code
75028
Country
United States
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Michael Park, Site 0034
Phone
000-000-0000
Facility Name
Texas Oncology - Fort Worth Cancer Center
City
Fort Worth
State/Province
Texas
ZIP/Postal Code
76104-2150
Country
United States
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Stephen Richey, Site 0057
Phone
817-413-1500
Facility Name
The University of Texas - MD Anderson Cancer Center - Genitourinary (GU) Cancer Center
City
Houston
State/Province
Texas
ZIP/Postal Code
77030-4004
Country
United States
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Sumit Subudhi, Site 0042
Phone
713-563-7213
Facility Name
Texas Oncology - McKinney
City
McKinney
State/Province
Texas
ZIP/Postal Code
75071-8106
Country
United States
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Monte Jones, Site 0045
Phone
972-867-3577
Facility Name
Texas Oncology- Tyler
City
Tyler
State/Province
Texas
ZIP/Postal Code
75702-8363
Country
United States
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Donald Richards, Site 0038
Phone
903-579-9800
Facility Name
Virginia Oncology Associates - Hampton
City
Hampton
State/Province
Virginia
ZIP/Postal Code
23666-5963
Country
United States
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Mark Fleming, Site 0056
Phone
757-873-9833
Facility Name
Medical College of Wisconsin
City
Milwaukee
State/Province
Wisconsin
ZIP/Postal Code
53226
Country
United States
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Deepak Kilari, Site 0060
Facility Name
Local Institution - 0070
City
Pergamino
State/Province
B
ZIP/Postal Code
B2700
Country
Argentina
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0070
Facility Name
Local Institution - 0055
City
Buenos Aires
State/Province
C
ZIP/Postal Code
C1417DTB
Country
Argentina
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0055
Facility Name
Local Institution - 0025
City
San Miguel De Tocuman
State/Province
T
ZIP/Postal Code
T4000IAK
Country
Argentina
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0025
Facility Name
Local Institution - 0039
City
Buenos Aires
ZIP/Postal Code
1426
Country
Argentina
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0039
Facility Name
Local Institution - 0046
City
Buenos Aires
ZIP/Postal Code
C1426ANZ
Country
Argentina
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0046
Facility Name
Local Institution - 0041
City
MarDel Lata
ZIP/Postal Code
B7600FZD
Country
Argentina
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0041
Facility Name
Local Institution - 0062
City
San Juan
ZIP/Postal Code
5400
Country
Argentina
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0062
Facility Name
Local Institution - 0019
City
Darlinghurst
State/Province
New South Wales
ZIP/Postal Code
2010
Country
Australia
Individual Site Status
Withdrawn
Facility Name
Local Institution - 0066
City
Elizabeth Vale
State/Province
South Australia
ZIP/Postal Code
5112
Country
Australia
Individual Site Status
Withdrawn
Facility Name
Local Institution - 0078
City
Heidelberg
State/Province
Victoria
ZIP/Postal Code
3084
Country
Australia
Individual Site Status
Withdrawn
Facility Name
Local Institution - 0067
City
Hamilton
State/Province
Ontario
ZIP/Postal Code
L8V 5C2
Country
Canada
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0067
Facility Name
Local Institution - 0083
City
Ottawa
State/Province
Ontario
ZIP/Postal Code
K1H 8L6
Country
Canada
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0083
Facility Name
Local Institution - 0028
City
Toronto
State/Province
Ontario
ZIP/Postal Code
M5G 2M9
Country
Canada
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0028
Facility Name
Local Institution - 0015
City
Québec
State/Province
Quebec
ZIP/Postal Code
G1R 3S3
Country
Canada
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0015
Facility Name
Local Institution - 0086
City
Angers
ZIP/Postal Code
49100
Country
France
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0086
Facility Name
Local Institution - 0011
City
Besancon
ZIP/Postal Code
25000
Country
France
Individual Site Status
Active, not recruiting
Facility Name
Local Institution - 0080
City
Bordeaux
ZIP/Postal Code
33076
Country
France
Individual Site Status
Active, not recruiting
Facility Name
Local Institution - 0031
City
Brest
ZIP/Postal Code
29609
Country
France
Individual Site Status
Active, not recruiting
Facility Name
Local Institution - 0023
City
Clermont-Ferrand CEDEX 01
ZIP/Postal Code
63011
Country
France
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0023
Facility Name
Local Institution - 0008
City
Lyon
ZIP/Postal Code
69008
Country
France
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0008
Facility Name
Local Institution - 0076
City
Marseille
ZIP/Postal Code
13009
Country
France
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0076
Facility Name
Local Institution - 0012
City
Nice CEDEX 2
ZIP/Postal Code
06189
Country
France
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0012
Facility Name
Local Institution - 0049
City
St Quentin
ZIP/Postal Code
02321
Country
France
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0049
Facility Name
Local Institution - 0003
City
Toulouse
ZIP/Postal Code
31100
Country
France
Individual Site Status
Active, not recruiting
Facility Name
Local Institution - 0014
City
Villejuif Cedex
ZIP/Postal Code
94800
Country
France
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0014
Facility Name
Local Institution - 0081
City
Thessaloniki
State/Province
B
ZIP/Postal Code
541 24
Country
Greece
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0081
Facility Name
Local Institution - 0010
City
Athens
State/Province
I
ZIP/Postal Code
115 28
Country
Greece
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0010
Facility Name
Local Institution - 0027
City
Athina
State/Province
I
ZIP/Postal Code
115 25
Country
Greece
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0027
Facility Name
Local Institution - 0007
City
Athina
State/Province
I
ZIP/Postal Code
115 28
Country
Greece
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0007
Facility Name
Local Institution - 0054
City
Marousi
State/Province
I
ZIP/Postal Code
151 25
Country
Greece
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0054
Facility Name
Local Institution - 0032
City
Peiraias
State/Province
I
ZIP/Postal Code
185 47
Country
Greece
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0032
Facility Name
Local Institution - 0077
City
Athens
ZIP/Postal Code
155 62
Country
Greece
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0077
Facility Name
Local Institution - 0069
City
Thessaloniki
ZIP/Postal Code
54645
Country
Greece
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0069
Facility Name
Local Institution - 0037
City
Milano
State/Province
MI
ZIP/Postal Code
20162
Country
Italy
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0037
Facility Name
Local Institution - 0021
City
Rozzano
State/Province
MI
ZIP/Postal Code
20089
Country
Italy
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0021
Facility Name
Local Institution - 0071
City
Meldola
ZIP/Postal Code
47014
Country
Italy
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0071
Facility Name
Local Institution - 0016
City
Modena
ZIP/Postal Code
41124
Country
Italy
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0016
Facility Name
Local Institution - 0029
City
Pozzuoli
ZIP/Postal Code
80078
Country
Italy
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0029
Facility Name
Local Institution - 0072
City
Roma
ZIP/Postal Code
152
Country
Italy
Individual Site Status
Withdrawn
Facility Name
Local Institution - 0074
City
Dordrecht
State/Province
ZH
ZIP/Postal Code
3318 AT
Country
Netherlands
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0074
Facility Name
Local Institution - 0002
City
Rotterdam
State/Province
ZH
ZIP/Postal Code
3015 GD
Country
Netherlands
Individual Site Status
Withdrawn
Facility Name
Local Institution - 0009
City
Rotterdam
ZIP/Postal Code
3045 PM
Country
Netherlands
Individual Site Status
Withdrawn
Facility Name
Local Institution - 0079
City
Madrid
State/Province
M
ZIP/Postal Code
28040
Country
Spain
Individual Site Status
Withdrawn
Facility Name
Local Institution - 0068
City
Badajoz
ZIP/Postal Code
06006
Country
Spain
Individual Site Status
Withdrawn
Facility Name
Local Institution - 0017
City
Santander-Cantabria
ZIP/Postal Code
39008
Country
Spain
Individual Site Status
Withdrawn
Facility Name
Local Institution - 0075
City
Brighton
State/Province
BNH
ZIP/Postal Code
BN2 5BE
Country
United Kingdom
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0075
Facility Name
Local Institution - 0065
City
Bristol
State/Province
BST
ZIP/Postal Code
BS2 8ED
Country
United Kingdom
Individual Site Status
Withdrawn
Facility Name
Local Institution - 0064
City
Blackburn
State/Province
LAN
ZIP/Postal Code
BB2 3HH
Country
United Kingdom
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0064
Facility Name
Local Institution - 0030
City
Preston
State/Province
LAN
ZIP/Postal Code
PR2 9HT
Country
United Kingdom
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0030
Facility Name
Local Institution - 0048
City
London
State/Province
LND
ZIP/Postal Code
W6 8RF
Country
United Kingdom
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0048
Facility Name
Local Institution - 0053
City
Guildford
State/Province
SRY
ZIP/Postal Code
GU2 7XX
Country
United Kingdom
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0053
Facility Name
Local Institution - 0051
City
Torquay
State/Province
TOB
ZIP/Postal Code
TQ2 7AA
Country
United Kingdom
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0051
Facility Name
Local Institution - 0073
City
West Midlands
State/Province
WLV
ZIP/Postal Code
WV10 0QP
Country
United Kingdom
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0073
Facility Name
Local Institution - 0013
City
Huddersfield
ZIP/Postal Code
HD3 3EA
Country
United Kingdom
Individual Site Status
Withdrawn
Facility Name
Local Institution - 0035
City
Sutton
ZIP/Postal Code
SM2 5PT
Country
United Kingdom
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0035
Facility Name
Local Institution - 0063
City
Truro
ZIP/Postal Code
TR1 3LJ
Country
United Kingdom
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Site 0063

12. IPD Sharing Statement

Links:
URL
https://www.bms.com/researchers-and-partners/clinical-trials-and-research.html
Description
BMS Clinical Trial Information
URL
https://www.bmsstudyconnect.com/us/en/home.html
Description
BMS Clinical Trial Patient Recruiting

Learn more about this trial

A Study of BMS-986218 or BMS-986218 Plus Nivolumab in Combination With Docetaxel in Participants With Metastatic Castration-resistant Prostate Cancer

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