Effect of Colchicine On Left Ventricle Function After Anterior Myocardial Infarction Assessed By Speckle Tracking
Anterior MI, Colchicine
About this trial
This is an interventional treatment trial for Anterior MI
Eligibility Criteria
Inclusion Criteria:
▪︎Anterior S-T segment elevation myocardial infarction with time of presentation less than 12 hours.
Exclusion Criteria:
- Severe renal impairment.
- Cardiac arrest.
- Cardiogenic shock.
Sites / Locations
- Ain Shams University hospitals
Arms of the Study
Arm 1
Arm 2
Active Comparator
No Intervention
Colchicine 0.5 mg oral tablet
Standard anti ischemic treatment
100 patients presented with anterior Myocardial infarction undergoing primary Percutaneous coronary intervention will receive colchicine tablet 1mg loading dose and colchicine 0.5 mg maintance dose for 6 months and will do longitudinal strain pattern echocardiography to asses left ventricles systolic function
100 patients presented with anterior myocardial infarction undergoing primary percutaneous coronary intervention will do longitudinal strain pattern echocardiography to asses left ventricles systolic function