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Effectiveness of Egg Versus Whey Protein Powder During Resistance Training

Primary Purpose

Muscle Atrophy

Status
Recruiting
Phase
Not Applicable
Locations
Canada
Study Type
Interventional
Intervention
Whole egg powder
Whey protein powder
Maltodextrin placebo
Sponsored by
University of Saskatchewan
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional other trial for Muscle Atrophy

Eligibility Criteria

18 Years - 35 Years (Adult)All SexesAccepts Healthy Volunteers

Inclusion Criteria:

  • Resistance training experience for at least one year

Exclusion Criteria:

  • Having taken any nutritional supplements the past 30 days
  • Currently using anabolic steroids
  • Currently taking corticosteroids
  • Allergies to dairy or egg products
  • Identifying any medical conditions as determined by the "Get Active Questionnaire"

Sites / Locations

  • University of ReginaRecruiting
  • University of SaskatchewanRecruiting

Arms of the Study

Arm 1

Arm 2

Arm 3

Arm Type

Experimental

Active Comparator

Placebo Comparator

Arm Label

Whole egg powder

Whey protein powder

Maltodextrin placebo

Arm Description

Dietary supplementation with whole egg powder after resistance training sessions

Dietary supplementation with whey protein powder after resistance training sessions

Dietary supplementation with maltodextrin placebo after resistance training sessions

Outcomes

Primary Outcome Measures

Change in lean tissue mass
Lean tissue mass measured by DXA

Secondary Outcome Measures

Change in fat mass
Fat mass measured by DXA
Change in biceps muscle thickness
biceps muscle thickness measured by ultrasound
Change in triceps muscle thickness
triceps muscle thickness measured by ultrasound
Change in quadriceps muscle thickness
quadriceps muscle thickness measured by ultrasound
Change in hamstrings muscle thickness
hamstrings muscle thickness measured by ultrasound
Change in bench press strength
Bench press strength (kg)
Change in leg squat strength
Leg squat strength (kg)
Change in knee extension strength
Isokinetic knee extension torque
Change in fasting glucose
Fasting glucose

Full Information

First Posted
January 11, 2022
Last Updated
June 2, 2023
Sponsor
University of Saskatchewan
Collaborators
Egg Farmers of Canada
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1. Study Identification

Unique Protocol Identification Number
NCT05206253
Brief Title
Effectiveness of Egg Versus Whey Protein Powder During Resistance Training
Official Title
Egg Versus Whey Protein as the Optimal Supplement for Fitness-conscious People
Study Type
Interventional

2. Study Status

Record Verification Date
June 2023
Overall Recruitment Status
Recruiting
Study Start Date
May 30, 2022 (Actual)
Primary Completion Date
August 31, 2023 (Anticipated)
Study Completion Date
August 31, 2023 (Anticipated)

3. Sponsor/Collaborators

Responsible Party, by Official Title
Principal Investigator
Name of the Sponsor
University of Saskatchewan
Collaborators
Egg Farmers of Canada

4. Oversight

Studies a U.S. FDA-regulated Drug Product
No
Studies a U.S. FDA-regulated Device Product
No
Data Monitoring Committee
No

5. Study Description

Brief Summary
Consumption of whole eggs has recently been shown to stimulate muscle protein synthesis to a greater degree than consumption of egg whites after a resistance training session. It is theorized that the egg yoke contains bio-active nutrients that enhance the protein provided by egg whites. The study will evaluate the effect of whole egg powder compared to whey protein powder and placebo over 12 weeks of resistance training in men and women who are participating in resistance training programs.
Detailed Description
Consuming whole eggs after resistance training sessions appears to be more effective for simulating muscle protein synthesis that simply consuming egg whites. The egg yolks might enhance the effect of protein derived from egg whites. The study will compare post-exercise supplementation with about 30 grams of protein derived from whole egg powder versus whey protein powder and placebo (maltodextrin) over a 12-week resistance training program. Resistance-trained men and women (n=120) will be randomized to consume either the whole-egg powder, whey protein powder or maltodextrin after resistance training 6 times per week for 12 weeks. The primary outcome measure is change in lean tissue mass. Secondary measures include change in fat mass, change in arm and leg muscle thickness, change in bench press, squat, and knee extension strength, and change in fasting blood glucose.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Muscle Atrophy

7. Study Design

Primary Purpose
Other
Study Phase
Not Applicable
Interventional Study Model
Parallel Assignment
Masking
ParticipantCare ProviderInvestigatorOutcomes Assessor
Allocation
Randomized
Enrollment
120 (Anticipated)

8. Arms, Groups, and Interventions

Arm Title
Whole egg powder
Arm Type
Experimental
Arm Description
Dietary supplementation with whole egg powder after resistance training sessions
Arm Title
Whey protein powder
Arm Type
Active Comparator
Arm Description
Dietary supplementation with whey protein powder after resistance training sessions
Arm Title
Maltodextrin placebo
Arm Type
Placebo Comparator
Arm Description
Dietary supplementation with maltodextrin placebo after resistance training sessions
Intervention Type
Dietary Supplement
Intervention Name(s)
Whole egg powder
Intervention Description
Nutritional supplementation during a 12 week resistance training program
Intervention Type
Dietary Supplement
Intervention Name(s)
Whey protein powder
Intervention Description
Nutritional supplementation during a 12 week resistance training program
Intervention Type
Dietary Supplement
Intervention Name(s)
Maltodextrin placebo
Intervention Description
Nutritional supplementation during a 12 week resistance training program
Primary Outcome Measure Information:
Title
Change in lean tissue mass
Description
Lean tissue mass measured by DXA
Time Frame
12 weeks
Secondary Outcome Measure Information:
Title
Change in fat mass
Description
Fat mass measured by DXA
Time Frame
12 weeks
Title
Change in biceps muscle thickness
Description
biceps muscle thickness measured by ultrasound
Time Frame
12 weeks
Title
Change in triceps muscle thickness
Description
triceps muscle thickness measured by ultrasound
Time Frame
12 weeks
Title
Change in quadriceps muscle thickness
Description
quadriceps muscle thickness measured by ultrasound
Time Frame
12 weeks
Title
Change in hamstrings muscle thickness
Description
hamstrings muscle thickness measured by ultrasound
Time Frame
12 weeks
Title
Change in bench press strength
Description
Bench press strength (kg)
Time Frame
12 weeks
Title
Change in leg squat strength
Description
Leg squat strength (kg)
Time Frame
12 weeks
Title
Change in knee extension strength
Description
Isokinetic knee extension torque
Time Frame
12 weeks
Title
Change in fasting glucose
Description
Fasting glucose
Time Frame
12 weeks

10. Eligibility

Sex
All
Minimum Age & Unit of Time
18 Years
Maximum Age & Unit of Time
35 Years
Accepts Healthy Volunteers
Accepts Healthy Volunteers
Eligibility Criteria
Inclusion Criteria: Resistance training experience for at least one year Exclusion Criteria: Having taken any nutritional supplements the past 30 days Currently using anabolic steroids Currently taking corticosteroids Allergies to dairy or egg products Identifying any medical conditions as determined by the "Get Active Questionnaire"
Central Contact Person:
First Name & Middle Initial & Last Name or Official Title & Degree
Philip Chilibeck, Ph.D.
Phone
306-966-1072
Email
phil.chilibeck@usask.ca
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Philip Chilibeck, Ph.D.
Organizational Affiliation
University of Saskatchewan
Official's Role
Principal Investigator
First Name & Middle Initial & Last Name & Degree
Darren Candow, Ph.D.
Organizational Affiliation
University of Regina
Official's Role
Principal Investigator
Facility Information:
Facility Name
University of Regina
City
Regina
State/Province
Saskatchewan
ZIP/Postal Code
S4S 0A2
Country
Canada
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Darren Candow, PhD
Phone
306-585-4906
Email
darren.candow@uregina.ca
First Name & Middle Initial & Last Name & Degree
Darren Candow, PhD
Facility Name
University of Saskatchewan
City
Saskatoon
State/Province
Saskatchewan
ZIP/Postal Code
S7N5B2
Country
Canada
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Philip Chilibeck, PhD
Phone
306-966-1072
Email
phil.chilibeck@usask.ca
First Name & Middle Initial & Last Name & Degree
John Ko, M.Sc
Phone
306-966-1305
Email
jongbum.ko@usask.ca
First Name & Middle Initial & Last Name & Degree
Philip Chilibeck, PhD

12. IPD Sharing Statement

Plan to Share IPD
No

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Effectiveness of Egg Versus Whey Protein Powder During Resistance Training

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